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The map label for this gene is infC [H]

Identifier: 120611522

GI number: 120611522

Start: 3148863

End: 3149384

Strand: Reverse

Name: infC [H]

Synonym: Aave_2858

Alternate gene names: 120611522

Gene position: 3149384-3148863 (Counterclockwise)

Preceding gene: 120611523

Following gene: 120611521

Centisome position: 58.84

GC content: 64.37

Gene sequence:

>522_bases
ATGGCTCCCGAGGTTCGCCTCTCCGGGCCGGACAACGAGCCGCTCGGGGTGGTCAGCCTCATGGAAGCCCTCCGCATGGC
GGGCGAGCTGGATGTGGACCTGGTGGAGATTGCCGCTACGGCCAACCCTCCCGTGTGCCGCCTTGTGGACTATGGAAAGT
TCAAGTACCAAGAGCAGAAGCGCGCGGCCGAGGCCAAGGCCAAGCAGACGGTCATCGAAATCAAGGAAGTGAAGTTCCGT
CCCGGTACGGACGACGGCGACTACAACATCAAGCTGCGCAACATCCGCCGTTTCCTCGCCGAAGGCGACAAGTGCAAGAT
CACGCTGCGCTTCCGCGGGCGTGAAATCACCCACCAGGAAATCGGCCTCGCGCTGCTCAACCGCATCCGCGACGACCTCG
GTGACACCATCGTGGTCGAGCAGTTCCCGAAGCTCGAAGGGCGCCAGATGATCATGATGATCGCGCCCGGCAAGCGCAAG
CCCGCCGCGAAGGCGGTGGCGGAAGGGGCGCCGGCCACCTGA

Upstream 100 bases:

>100_bases
TTTTTCGTGGCTTGTTGATTGAAGGAATACAGCCATCGCTACTGAATTTCGTGACCGTCGCCAGCGCGAGGAGCGCAAGC
ACCGCCTGAACCGTGAAATC

Downstream 100 bases:

>100_bases
GTGGCGGGCCAGGAGTGTCTCCGGATGCATGCGAGTGCATCCGGGCATGGCATGGGTCTCGTACCCTGCCGCGGCCGTCC
ATGGCGGCCGCAAAAGAAGT

Product: translation initiation factor 3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 173; Mature: 172

Protein sequence:

>173_residues
MAPEVRLSGPDNEPLGVVSLMEALRMAGELDVDLVEIAATANPPVCRLVDYGKFKYQEQKRAAEAKAKQTVIEIKEVKFR
PGTDDGDYNIKLRNIRRFLAEGDKCKITLRFRGREITHQEIGLALLNRIRDDLGDTIVVEQFPKLEGRQMIMMIAPGKRK
PAAKAVAEGAPAT

Sequences:

>Translated_173_residues
MAPEVRLSGPDNEPLGVVSLMEALRMAGELDVDLVEIAATANPPVCRLVDYGKFKYQEQKRAAEAKAKQTVIEIKEVKFR
PGTDDGDYNIKLRNIRRFLAEGDKCKITLRFRGREITHQEIGLALLNRIRDDLGDTIVVEQFPKLEGRQMIMMIAPGKRK
PAAKAVAEGAPAT
>Mature_172_residues
APEVRLSGPDNEPLGVVSLMEALRMAGELDVDLVEIAATANPPVCRLVDYGKFKYQEQKRAAEAKAKQTVIEIKEVKFRP
GTDDGDYNIKLRNIRRFLAEGDKCKITLRFRGREITHQEIGLALLNRIRDDLGDTIVVEQFPKLEGRQMIMMIAPGKRKP
AAKAVAEGAPAT

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=160, Percent_Identity=62.5, Blast_Score=195, Evalue=1e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 19244; Mature: 19112

Theoretical pI: Translated: 9.14; Mature: 9.14

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPEVRLSGPDNEPLGVVSLMEALRMAGELDVDLVEIAATANPPVCRLVDYGKFKYQEQK
CCCCEECCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEEECCCCHHHHHHH
RAAEAKAKQTVIEIKEVKFRPGTDDGDYNIKLRNIRRFLAEGDKCKITLRFRGREITHQE
HHHHHHHHHHHHHHHHEEECCCCCCCCEEEEHHHHHHHHHCCCEEEEEEEECCCCCCHHH
IGLALLNRIRDDLGDTIVVEQFPKLEGRQMIMMIAPGKRKPAAKAVAEGAPAT
HHHHHHHHHHHHHCCEEEEECCCCCCCCEEEEEECCCCCCCHHHHHHCCCCCC
>Mature Secondary Structure 
APEVRLSGPDNEPLGVVSLMEALRMAGELDVDLVEIAATANPPVCRLVDYGKFKYQEQK
CCCEECCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEEECCCCHHHHHHH
RAAEAKAKQTVIEIKEVKFRPGTDDGDYNIKLRNIRRFLAEGDKCKITLRFRGREITHQE
HHHHHHHHHHHHHHHHEEECCCCCCCCEEEEHHHHHHHHHCCCEEEEEEEECCCCCCHHH
IGLALLNRIRDDLGDTIVVEQFPKLEGRQMIMMIAPGKRKPAAKAVAEGAPAT
HHHHHHHHHHHHHCCEEEEECCCCCCCCEEEEEECCCCCCCHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]