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The map label for this gene is soxB [H]

Identifier: 120611470

GI number: 120611470

Start: 3080143

End: 3081543

Strand: Direct

Name: soxB [H]

Synonym: Aave_2806

Alternate gene names: 120611470

Gene position: 3080143-3081543 (Clockwise)

Preceding gene: 120611469

Following gene: 120611479

Centisome position: 57.54

GC content: 71.02

Gene sequence:

>1401_bases
ATGACCGCCGGCCTGCTGCCCCGGCGCCACGCGCCGTCCCTGCGTTCCGTCCTGACCGAAAAGCGAGATCCATCCATGCA
ACAGCCGCTGCGCCTCATCGAAACGCCCTCCCCCTTGCCCACCAGTGCCGATGCCGTCGTGATCGGCGGAGGAATCATCG
GCGTGTTCGCCGCCTACTATCTGGCCCGCAGGGGCATGTCGGTCGCGCTGGTCGAAAAGGGCGTCATCGGCGCCGAACAG
TCCAGCCGCAACTGGGGCTGGTGCCGCCAGCAGAACCGGGACGCGCGCGAACTGCCCATGGCCACGAAAAGCCTGGAGCT
CTGGGAACAGTTCGCCGCCGATTCCGGAGAGGACACGGGCTTCCGGCGCTGCGGCCTGTTCTACCTGAGCAACGACGAAG
CCGAACTCGACCGCTGGGCCCGCTGGGGCGTCTTCGCGAAATCCGCCGGCGTCACCACGCACATGTTGAGCGCCGAGGAA
GCCACGCGGCGCGGCAGCGCGACGGGCCGCCCCTGGAAGGGCGGCGTGCTCTCTCCCAGCGACGGCACTGCCGATCCCGC
CAAGGCCGCTCCGGCCGCCGCCACCGCATTCATGAAGCTCGGAGGTACCGTGCACCAGAACTGCGCGGCCCGGGGCATCG
AGCTGCAGGGCGGACGCGTCAGCGGCGTGGTCACCGAGGCCGGAACCATCCGGACCCGCACCGCCATCTATGCCGGGGGC
GCATGGGCGTCCTCGTTCTGCCGCCAATTGGGAATCCGCTTTCCCCAGGCTACGGTCCGCCAGTCCATCGTGCGCGTTTC
GGCGATCGCCGAGGCGCTGCCCGACACACTGCACACGGCGGGCGTGTCCCTCACCCGCCGCAGCGACGGCAGCTACACGC
TGGCCATCAGCGGGCGCGGCCGGGTGGATCCCACGCCGCAGTTGCTGCGCTTCGCGCCGCAATTCGTGCCGATGTTCGCC
AAGCGCTGGCGCAACGTGTTCCCCGGTGGCCTGGAGGGCATCCGGAGCGGCCACGAAACGCTGAGCCGCTGGCGCCTGGA
TGCTCCGACGCCGATGGAGCGCATCCGCGTGCTTGATCCGAAGGCGGATCCTGCGGCCGTCCGGGAAACCCACCGCCGGG
CCGTCGCCCTGCTGCCCGCGCTGCGGGAGGCGCGCATCGCCAACGCCTGGGCCGGTTACGTGGACAGCACGCCCGACGGC
GTGCCGGGCATCGGCGAGGTGCAGGGCATCCCCGGGTTCATCCTGGCCGCGGGGTTCTCGGGCCACGGCTTCGGCATCGG
GCCGGGGGCGGGCCACCTGATCGCCGACCTCGCCAGCGGCGACACGCCCCTCTTCGATCCCCGCCCCTACGACCCCGAGC
GGTTCAGGCACTCGGCGTGGGGCAAGGTCGCGGACTTCTAA

Upstream 100 bases:

>100_bases
GCTACAAGCGCTCGGGCAACGGACGCGAATACGGCGTCGAGGGGCTCCACGAGTACCTCGAAACCAAAGCCATCCTGGGA
TGGGCCGGAGGCGCACCCGC

Downstream 100 bases:

>100_bases
GCCGCAGGGCGGCCCGACGCGTCAGAAGTCCACCTTCACCCCCACCTTCAGGCTGCGCCCTGGCAACGGCGCTTTCGGGA
ACGCCGTGGTCGTCAGGATC

Product: FAD dependent oxidoreductase

Products: NA

Alternate protein names: Sarcosine oxidase subunit B [H]

Number of amino acids: Translated: 466; Mature: 465

Protein sequence:

>466_residues
MTAGLLPRRHAPSLRSVLTEKRDPSMQQPLRLIETPSPLPTSADAVVIGGGIIGVFAAYYLARRGMSVALVEKGVIGAEQ
SSRNWGWCRQQNRDARELPMATKSLELWEQFAADSGEDTGFRRCGLFYLSNDEAELDRWARWGVFAKSAGVTTHMLSAEE
ATRRGSATGRPWKGGVLSPSDGTADPAKAAPAAATAFMKLGGTVHQNCAARGIELQGGRVSGVVTEAGTIRTRTAIYAGG
AWASSFCRQLGIRFPQATVRQSIVRVSAIAEALPDTLHTAGVSLTRRSDGSYTLAISGRGRVDPTPQLLRFAPQFVPMFA
KRWRNVFPGGLEGIRSGHETLSRWRLDAPTPMERIRVLDPKADPAAVRETHRRAVALLPALREARIANAWAGYVDSTPDG
VPGIGEVQGIPGFILAAGFSGHGFGIGPGAGHLIADLASGDTPLFDPRPYDPERFRHSAWGKVADF

Sequences:

>Translated_466_residues
MTAGLLPRRHAPSLRSVLTEKRDPSMQQPLRLIETPSPLPTSADAVVIGGGIIGVFAAYYLARRGMSVALVEKGVIGAEQ
SSRNWGWCRQQNRDARELPMATKSLELWEQFAADSGEDTGFRRCGLFYLSNDEAELDRWARWGVFAKSAGVTTHMLSAEE
ATRRGSATGRPWKGGVLSPSDGTADPAKAAPAAATAFMKLGGTVHQNCAARGIELQGGRVSGVVTEAGTIRTRTAIYAGG
AWASSFCRQLGIRFPQATVRQSIVRVSAIAEALPDTLHTAGVSLTRRSDGSYTLAISGRGRVDPTPQLLRFAPQFVPMFA
KRWRNVFPGGLEGIRSGHETLSRWRLDAPTPMERIRVLDPKADPAAVRETHRRAVALLPALREARIANAWAGYVDSTPDG
VPGIGEVQGIPGFILAAGFSGHGFGIGPGAGHLIADLASGDTPLFDPRPYDPERFRHSAWGKVADF
>Mature_465_residues
TAGLLPRRHAPSLRSVLTEKRDPSMQQPLRLIETPSPLPTSADAVVIGGGIIGVFAAYYLARRGMSVALVEKGVIGAEQS
SRNWGWCRQQNRDARELPMATKSLELWEQFAADSGEDTGFRRCGLFYLSNDEAELDRWARWGVFAKSAGVTTHMLSAEEA
TRRGSATGRPWKGGVLSPSDGTADPAKAAPAAATAFMKLGGTVHQNCAARGIELQGGRVSGVVTEAGTIRTRTAIYAGGA
WASSFCRQLGIRFPQATVRQSIVRVSAIAEALPDTLHTAGVSLTRRSDGSYTLAISGRGRVDPTPQLLRFAPQFVPMFAK
RWRNVFPGGLEGIRSGHETLSRWRLDAPTPMERIRVLDPKADPAAVRETHRRAVALLPALREARIANAWAGYVDSTPDGV
PGIGEVQGIPGFILAAGFSGHGFGIGPGAGHLIADLASGDTPLFDPRPYDPERFRHSAWGKVADF

Specific function: Catalyzes the oxidative demethylation of sarcosine to yield glycine, hydrogen peroxide and 5,10- methylenetetrahydrofolate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the soxB family [H]

Homologues:

Organism=Homo sapiens, GI197927446, Length=434, Percent_Identity=27.4193548387097, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI21361378, Length=434, Percent_Identity=27.4193548387097, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI24797151, Length=421, Percent_Identity=24.4655581947743, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI194306651, Length=420, Percent_Identity=21.6666666666667, Blast_Score=76, Evalue=9e-14,
Organism=Drosophila melanogaster, GI20130091, Length=437, Percent_Identity=24.9427917620137, Blast_Score=108, Evalue=7e-24,
Organism=Drosophila melanogaster, GI28571104, Length=437, Percent_Identity=24.0274599542334, Blast_Score=85, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR006278 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.5.3.1 [H]

Molecular weight: Translated: 50038; Mature: 49907

Theoretical pI: Translated: 10.31; Mature: 10.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAGLLPRRHAPSLRSVLTEKRDPSMQQPLRLIETPSPLPTSADAVVIGGGIIGVFAAYY
CCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCEEEECCHHHHHHHHHH
LARRGMSVALVEKGVIGAEQSSRNWGWCRQQNRDARELPMATKSLELWEQFAADSGEDTG
HHHCCCEEEEECCCCCCCCCCCCCCCHHHHCCCCHHHCCCHHHHHHHHHHHHCCCCCCCC
FRRCGLFYLSNDEAELDRWARWGVFAKSAGVTTHMLSAEEATRRGSATGRPWKGGVLSPS
CEEEEEEEEECCHHHHHHHHHHHHHHHCCCCHHHHHCHHHHHHCCCCCCCCCCCCCCCCC
DGTADPAKAAPAAATAFMKLGGTVHQNCAARGIELQGGRVSGVVTEAGTIRTRTAIYAGG
CCCCCCHHCCHHHHHHHHHHCCHHHHHHHHCCEEECCCEEEEEEECCCCEEEEEEEEECC
AWASSFCRQLGIRFPQATVRQSIVRVSAIAEALPDTLHTAGVSLTRRSDGSYTLAISGRG
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEECCCC
RVDPTPQLLRFAPQFVPMFAKRWRNVFPGGLEGIRSGHETLSRWRLDAPTPMERIRVLDP
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHEEECC
KADPAAVRETHRRAVALLPALREARIANAWAGYVDSTPDGVPGIGEVQGIPGFILAAGFS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCC
GHGFGIGPGAGHLIADLASGDTPLFDPRPYDPERFRHSAWGKVADF
CCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TAGLLPRRHAPSLRSVLTEKRDPSMQQPLRLIETPSPLPTSADAVVIGGGIIGVFAAYY
CCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCEEEECCHHHHHHHHHH
LARRGMSVALVEKGVIGAEQSSRNWGWCRQQNRDARELPMATKSLELWEQFAADSGEDTG
HHHCCCEEEEECCCCCCCCCCCCCCCHHHHCCCCHHHCCCHHHHHHHHHHHHCCCCCCCC
FRRCGLFYLSNDEAELDRWARWGVFAKSAGVTTHMLSAEEATRRGSATGRPWKGGVLSPS
CEEEEEEEEECCHHHHHHHHHHHHHHHCCCCHHHHHCHHHHHHCCCCCCCCCCCCCCCCC
DGTADPAKAAPAAATAFMKLGGTVHQNCAARGIELQGGRVSGVVTEAGTIRTRTAIYAGG
CCCCCCHHCCHHHHHHHHHHCCHHHHHHHHCCEEECCCEEEEEEECCCCEEEEEEEEECC
AWASSFCRQLGIRFPQATVRQSIVRVSAIAEALPDTLHTAGVSLTRRSDGSYTLAISGRG
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEECCCC
RVDPTPQLLRFAPQFVPMFAKRWRNVFPGGLEGIRSGHETLSRWRLDAPTPMERIRVLDP
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHEEECC
KADPAAVRETHRRAVALLPALREARIANAWAGYVDSTPDGVPGIGEVQGIPGFILAAGFS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCC
GHGFGIGPGAGHLIADLASGDTPLFDPRPYDPERFRHSAWGKVADF
CCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]