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The map label for this gene is gntK [H]

Identifier: 120611461

GI number: 120611461

Start: 3070649

End: 3071278

Strand: Reverse

Name: gntK [H]

Synonym: Aave_2797

Alternate gene names: 120611461

Gene position: 3071278-3070649 (Counterclockwise)

Preceding gene: 120611463

Following gene: 120611460

Centisome position: 57.38

GC content: 72.54

Gene sequence:

>630_bases
ATGAACTCAACGGATAGCGCTATCCAAGGCAGGCCACTGCCTGCGGTGGTCGTGATGGGCGTGTCAGGCTGCGGCAAATC
CAGCGTCGCGGCCGCGGCCGCTGCGCTGCTGGGCTGGACCCTGCACGAAGGCGATGCCTACCATTCGCCCGAGAGCGTCG
CCAAGATGCGCGCGGGCCAGCCGCTCACCGACGAGGACCGGGCCGGCTGGCTGGACCGGCTCGCCCATCTTCTGGCGCAC
GCCGTGCACCCCGCCGATGCTGTCGGGCATGGGGGCATCGTGCTGACCTGCTCGGCGCTGCGCCGCCGCTACCGCGACCA
CCTGCGCGCCGCCGCGCCCGGGCTGCGCTTCGCGTTCCTGGAACTCGACTACGACGAAGCGCTCGCGCGCGTCAGCCACC
GGCCGGGCCATTTCTTCTCGCCCACGCTGGTCGCCAACCAGTTCGCCACGCTGGAATCGCCGCGAGGCGAACCCGGCGTG
CTCGCGCTGGACGCCACGCGGCCCATCCACGACCTGGGTGCCGCCATCGCGCATTGGCTGCACGGCGACGGCGGCGCAGA
GGCTGCCGCGCCATTCCCCCACGCCCCAGGCGCCCCTTGCGCGCCGGCCCCTTCCGGAGACACCGCATGA

Upstream 100 bases:

>100_bases
CGCTATCTTGCTCAGGGTTAACGACAGGGCAAGGCGATTGACCTCATTCATTCGACGGAGACGACGCGGCAGGCTTCCCC
GGGAAGCGTCCGCGATTTTT

Downstream 100 bases:

>100_bases
ACGACCACCCCGCGCGCGACAAACCCGCGCTCCAGCGCTTCGCGGAGCATTTCATGGTGCTGGCCCTGGCCGGCATGGTC
GTGGCCGTGTTCGTGAACGT

Product: gluconate kinase

Products: NA

Alternate protein names: Gluconate kinase 2 [H]

Number of amino acids: Translated: 209; Mature: 209

Protein sequence:

>209_residues
MNSTDSAIQGRPLPAVVVMGVSGCGKSSVAAAAAALLGWTLHEGDAYHSPESVAKMRAGQPLTDEDRAGWLDRLAHLLAH
AVHPADAVGHGGIVLTCSALRRRYRDHLRAAAPGLRFAFLELDYDEALARVSHRPGHFFSPTLVANQFATLESPRGEPGV
LALDATRPIHDLGAAIAHWLHGDGGAEAAAPFPHAPGAPCAPAPSGDTA

Sequences:

>Translated_209_residues
MNSTDSAIQGRPLPAVVVMGVSGCGKSSVAAAAAALLGWTLHEGDAYHSPESVAKMRAGQPLTDEDRAGWLDRLAHLLAH
AVHPADAVGHGGIVLTCSALRRRYRDHLRAAAPGLRFAFLELDYDEALARVSHRPGHFFSPTLVANQFATLESPRGEPGV
LALDATRPIHDLGAAIAHWLHGDGGAEAAAPFPHAPGAPCAPAPSGDTA
>Mature_209_residues
MNSTDSAIQGRPLPAVVVMGVSGCGKSSVAAAAAALLGWTLHEGDAYHSPESVAKMRAGQPLTDEDRAGWLDRLAHLLAH
AVHPADAVGHGGIVLTCSALRRRYRDHLRAAAPGLRFAFLELDYDEALARVSHRPGHFFSPTLVANQFATLESPRGEPGV
LALDATRPIHDLGAAIAHWLHGDGGAEAAAPFPHAPGAPCAPAPSGDTA

Specific function: Gluconate utilization system GNT-I. [C]

COG id: COG3265

COG function: function code G; Gluconate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gluconokinase gntK/gntV family [H]

Homologues:

Organism=Homo sapiens, GI299758445, Length=185, Percent_Identity=33.5135135135135, Blast_Score=102, Evalue=3e-22,
Organism=Escherichia coli, GI87082265, Length=154, Percent_Identity=39.6103896103896, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1790719, Length=156, Percent_Identity=36.5384615384615, Blast_Score=112, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI25146487, Length=160, Percent_Identity=41.25, Blast_Score=114, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6320454, Length=150, Percent_Identity=32, Blast_Score=83, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR006001 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.12 [H]

Molecular weight: Translated: 21698; Mature: 21698

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSTDSAIQGRPLPAVVVMGVSGCGKSSVAAAAAALLGWTLHEGDAYHSPESVAKMRAGQ
CCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCC
PLTDEDRAGWLDRLAHLLAHAVHPADAVGHGGIVLTCSALRRRYRDHLRAAAPGLRFAFL
CCCCCHHHHHHHHHHHHHHHHCCCHHHCCCCCEEEEHHHHHHHHHHHHHHHCCCCEEEEE
ELDYDEALARVSHRPGHFFSPTLVANQFATLESPRGEPGVLALDATRPIHDLGAAIAHWL
ECCHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHH
HGDGGAEAAAPFPHAPGAPCAPAPSGDTA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNSTDSAIQGRPLPAVVVMGVSGCGKSSVAAAAAALLGWTLHEGDAYHSPESVAKMRAGQ
CCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCC
PLTDEDRAGWLDRLAHLLAHAVHPADAVGHGGIVLTCSALRRRYRDHLRAAAPGLRFAFL
CCCCCHHHHHHHHHHHHHHHHCCCHHHCCCCCEEEEHHHHHHHHHHHHHHHCCCCEEEEE
ELDYDEALARVSHRPGHFFSPTLVANQFATLESPRGEPGVLALDATRPIHDLGAAIAHWL
ECCHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHH
HGDGGAEAAAPFPHAPGAPCAPAPSGDTA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9135111; 9278503; 8655507; 11468405 [H]