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The map label for this gene is fabG [C]

Identifier: 120611452

GI number: 120611452

Start: 3061255

End: 3061947

Strand: Reverse

Name: fabG [C]

Synonym: Aave_2788

Alternate gene names: 120611452

Gene position: 3061947-3061255 (Counterclockwise)

Preceding gene: 120611453

Following gene: 120611451

Centisome position: 57.2

GC content: 65.66

Gene sequence:

>693_bases
ATGAAGACACCCCCTGACCGGAACAAGGTATTGATTCTCGGAGCATCCCGCGGCCTGGGCCGCAGCCTGCTGGGCGCCTT
CGGCGCGGACGGCCATGCCGTGACCGCCGTCGCCAGGCGCTTCGACGGCAGCGAGGCCGAGCAGGCCGGACGCATCCTGA
CTGCAGATCTCACGCAGGAGGCGGGACTGGCGTCGGTGACCGCCGACATGCAGCGGGCCGACTATGACTGCATCATCTAT
GTGGCGGGCATCTGGGAGCAGCAAGGCTTCGAGCGCGCCTCGGAACAGGAGGTTCGCGGCATCGTCGCCACGAACATCAC
GGCACCGCTGATCATCGGCCAGCGGTTGCTCGCGCTGTGCGCTGCAACACCACCTCGCCGGCGCCACTATTTCCTTATCG
GGTCAACCAGCGGCCTCGACAACTCCGGTAGCACGTCATGTGCATATGTCGCGTCCAAGTTCGCGTTGCGAGGCCTGACG
CACTCGCTGCGCGAACAGGGAAGGCCGTTGCGCCTGCATGTCACCTGCCTTTCCCCGGGATCGATCCGCAGTGACCAGAG
CGGCCAGTCGTCCCACCCGGCGCGCATACCGCCGGACGACATCTACCAATTGATCCGCTGCATTCTCTCGCTGGACGACC
CGACCCTGGTGAAGGAGCTCGTCGTCCCGGCCATCGAGGACACCGACGTCTAG

Upstream 100 bases:

>100_bases
GTACCGTACGGCACGAGACCAGCGAGTGGACTGCCATCTGCTCAGACGCACCGTCGAATCGAACGGCATGCCAATGCCAC
CCTGCGCGAGGCTTTGAAAA

Downstream 100 bases:

>100_bases
GAGGATTTCATGCCGAACATCGCCATCATCCGTCCACCGCACACCTATCGGTACAACGATCTCGACGTGCGGGAGGACGC
CATCATCTCCTACTGGCTCG

Product: short-chain dehydrogenase/reductase SDR

Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]

Alternate protein names: Oxidoreductase; Short Chain Dehydrogenase Family Protein; Short Chain Dehydrogenase/Reductase; Oxidoreductase Short Chain Dehydrogenase/Reductase Family; Short Chain Dehydrogenase/Reductase Family Oxidoreductase; Short-Chain Dehydrogenase/Reductase Sdr; Dehydrogenase/Reductase

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MKTPPDRNKVLILGASRGLGRSLLGAFGADGHAVTAVARRFDGSEAEQAGRILTADLTQEAGLASVTADMQRADYDCIIY
VAGIWEQQGFERASEQEVRGIVATNITAPLIIGQRLLALCAATPPRRRHYFLIGSTSGLDNSGSTSCAYVASKFALRGLT
HSLREQGRPLRLHVTCLSPGSIRSDQSGQSSHPARIPPDDIYQLIRCILSLDDPTLVKELVVPAIEDTDV

Sequences:

>Translated_230_residues
MKTPPDRNKVLILGASRGLGRSLLGAFGADGHAVTAVARRFDGSEAEQAGRILTADLTQEAGLASVTADMQRADYDCIIY
VAGIWEQQGFERASEQEVRGIVATNITAPLIIGQRLLALCAATPPRRRHYFLIGSTSGLDNSGSTSCAYVASKFALRGLT
HSLREQGRPLRLHVTCLSPGSIRSDQSGQSSHPARIPPDDIYQLIRCILSLDDPTLVKELVVPAIEDTDV
>Mature_230_residues
MKTPPDRNKVLILGASRGLGRSLLGAFGADGHAVTAVARRFDGSEAEQAGRILTADLTQEAGLASVTADMQRADYDCIIY
VAGIWEQQGFERASEQEVRGIVATNITAPLIIGQRLLALCAATPPRRRHYFLIGSTSGLDNSGSTSCAYVASKFALRGLT
HSLREQGRPLRLHVTCLSPGSIRSDQSGQSSHPARIPPDDIYQLIRCILSLDDPTLVKELVVPAIEDTDV

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.1.1.100 [C]

Molecular weight: Translated: 24707; Mature: 24707

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTPPDRNKVLILGASRGLGRSLLGAFGADGHAVTAVARRFDGSEAEQAGRILTADLTQE
CCCCCCCCEEEEEECCCCCCHHHHHHHCCCCHHHHHHHHHCCCCCHHHCCCEEEECCHHC
AGLASVTADMQRADYDCIIYVAGIWEQQGFERASEQEVRGIVATNITAPLIIGQRLLALC
CCHHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
AATPPRRRHYFLIGSTSGLDNSGSTSCAYVASKFALRGLTHSLREQGRPLRLHVTCLSPG
HCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCC
SIRSDQSGQSSHPARIPPDDIYQLIRCILSLDDPTLVKELVVPAIEDTDV
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKTPPDRNKVLILGASRGLGRSLLGAFGADGHAVTAVARRFDGSEAEQAGRILTADLTQE
CCCCCCCCEEEEEECCCCCCHHHHHHHCCCCHHHHHHHHHCCCCCHHHCCCEEEECCHHC
AGLASVTADMQRADYDCIIYVAGIWEQQGFERASEQEVRGIVATNITAPLIIGQRLLALC
CCHHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
AATPPRRRHYFLIGSTSGLDNSGSTSCAYVASKFALRGLTHSLREQGRPLRLHVTCLSPG
HCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCC
SIRSDQSGQSSHPARIPPDDIYQLIRCILSLDDPTLVKELVVPAIEDTDV
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]

Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA