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The map label for this gene is mltB [H]

Identifier: 120610834

GI number: 120610834

Start: 2372882

End: 2373967

Strand: Reverse

Name: mltB [H]

Synonym: Aave_2160

Alternate gene names: 120610834

Gene position: 2373967-2372882 (Counterclockwise)

Preceding gene: 120610835

Following gene: 120610833

Centisome position: 44.35

GC content: 71.45

Gene sequence:

>1086_bases
ATGCCTTTCGCCCGTTCCACCGCCCTTCTCGTCCTCGCCTGCGCCGCCACGATGGTCCTGCCGCCGGCCGCCATGGCCCA
GAAACCCGCCAGGAAGAAGGAGAAGCAGGCCGTCCCGGAGGTGCTCTACGCGCAGCGTCCCGAGGCCTTGCGCTTCGCCG
ACGACCTGGCCGAGCGCCGCGGCCTGGACCGCGAGTGGGTGCGGCAGGCCATCGGGCAGGCGCGGTTCCTGCCGCAGGTG
CCGCGCCTCATGCTGCCGGCGCCCAGGGGCACCGCCAAGAACTGGGCCGCCTACCGCGCCCGGTTCGTGGAGCCGGTGCG
CATCCGCGCGGGCGTGCGCTTCTGGAACGAGCATGCCGACACGCTGGCGCGCGCCGAGCGCGAATACGGCGTGCCGGCCT
CGATCATCGTCGGCATCCTGGGCGTGGAGACGCTCTACGGGCAGCACATGGGCAGCTTCCGCGTGATGGACGCGCTCGCC
ACGCTGGCCTTCGATTTTCCGGCCGCGCACCCGCGCGCCACGGAGCGGCAGGCCTTCTTCCGGGGCGAATTGGAGCAGTT
CCTGAGCCTGGCCGACCGCACGGGCACCGATCCCTTCGTCCTGCGCGGCAGCTACGCGGGCGCCATGGGCATGGGCCAGT
TCATGCCTACCAGTTGGGCACGCTGGGCGGTGGATTTCGACGGCGACGGCCGCATCGACCTGTTCAACAGCACTGCCGAC
GCGATCGGCTCGGTCGCCAACTACTTCCAGGCCCACGGCTGGGTGAGCGGGCTGCCCACGCATTACGCCGTGGCCTTCGA
CGACAACGGCCTGCGCCTGCCCGAACTGCTCGCGCCCGACATCCTGCCCACGTTCACCGCCGCCGGGATGCAGGAGCGCG
GCGCCCGCCCCCTGCCGGCGGACGGCGCCGCCACGCAGCCCGACGCCGCCGGCCCCCTGGCGCTGATCGAGTTGCAGAAC
GGCAACGCCCCGGCCGCATACGTGGCCGGCACGCGCAATTTCTACGTGGTCACGCGCTACAACTGGTCGAGCTATTACGC
GATGGCGGTGATCGATCTCGGGCAGGAAGTGTCGGCGGCGCGGTAG

Upstream 100 bases:

>100_bases
GCGCGGCCTGCGCTGGCCCTCGTCCGGCCCCCCTTCTGCGCAGCACTGATCCCGGGCCAGGCCCGCCGCCGTTTTCCTGT
ACTCGACCCTGCCTTCCGCG

Downstream 100 bases:

>100_bases
CGCGCTGCGCATGCGCGGGACGGCATCGGGTCTCTGACCTGCATCAAGGCCCATGGATTTCGCGCCCCCCCTCGGGCCTG
CGTCATCCAAAATAGATTCA

Product: lytic murein transglycosylase B

Products: Muramic Acid Residue [C]

Alternate protein names: 35 kDa soluble lytic transglycosylase; Murein hydrolase B; Slt35 [H]

Number of amino acids: Translated: 361; Mature: 360

Protein sequence:

>361_residues
MPFARSTALLVLACAATMVLPPAAMAQKPARKKEKQAVPEVLYAQRPEALRFADDLAERRGLDREWVRQAIGQARFLPQV
PRLMLPAPRGTAKNWAAYRARFVEPVRIRAGVRFWNEHADTLARAEREYGVPASIIVGILGVETLYGQHMGSFRVMDALA
TLAFDFPAAHPRATERQAFFRGELEQFLSLADRTGTDPFVLRGSYAGAMGMGQFMPTSWARWAVDFDGDGRIDLFNSTAD
AIGSVANYFQAHGWVSGLPTHYAVAFDDNGLRLPELLAPDILPTFTAAGMQERGARPLPADGAATQPDAAGPLALIELQN
GNAPAAYVAGTRNFYVVTRYNWSSYYAMAVIDLGQEVSAAR

Sequences:

>Translated_361_residues
MPFARSTALLVLACAATMVLPPAAMAQKPARKKEKQAVPEVLYAQRPEALRFADDLAERRGLDREWVRQAIGQARFLPQV
PRLMLPAPRGTAKNWAAYRARFVEPVRIRAGVRFWNEHADTLARAEREYGVPASIIVGILGVETLYGQHMGSFRVMDALA
TLAFDFPAAHPRATERQAFFRGELEQFLSLADRTGTDPFVLRGSYAGAMGMGQFMPTSWARWAVDFDGDGRIDLFNSTAD
AIGSVANYFQAHGWVSGLPTHYAVAFDDNGLRLPELLAPDILPTFTAAGMQERGARPLPADGAATQPDAAGPLALIELQN
GNAPAAYVAGTRNFYVVTRYNWSSYYAMAVIDLGQEVSAAR
>Mature_360_residues
PFARSTALLVLACAATMVLPPAAMAQKPARKKEKQAVPEVLYAQRPEALRFADDLAERRGLDREWVRQAIGQARFLPQVP
RLMLPAPRGTAKNWAAYRARFVEPVRIRAGVRFWNEHADTLARAEREYGVPASIIVGILGVETLYGQHMGSFRVMDALAT
LAFDFPAAHPRATERQAFFRGELEQFLSLADRTGTDPFVLRGSYAGAMGMGQFMPTSWARWAVDFDGDGRIDLFNSTADA
IGSVANYFQAHGWVSGLPTHYAVAFDDNGLRLPELLAPDILPTFTAAGMQERGARPLPADGAATQPDAAGPLALIELQNG
NAPAAYVAGTRNFYVVTRYNWSSYYAMAVIDLGQEVSAAR

Specific function: Murein-degrading enzyme. Catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N- acetylglucosamine residues in peptidoglycan. May play a role in recycling of muropeptides during cell elongation and/or cell division [H]

COG id: COG2951

COG function: function code M; Membrane-bound lytic murein transglycosylase B

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor; Periplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789053, Length=328, Percent_Identity=42.6829268292683, Blast_Score=236, Evalue=2e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011757 [H]

Pfam domain/function: NA

EC number: 3.2.1.- [C]

Molecular weight: Translated: 39506; Mature: 39375

Theoretical pI: Translated: 8.39; Mature: 8.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFARSTALLVLACAATMVLPPAAMAQKPARKKEKQAVPEVLYAQRPEALRFADDLAERR
CCCCHHHHHHHHHHHHHHHCCCHHHHHCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
GLDREWVRQAIGQARFLPQVPRLMLPAPRGTAKNWAAYRARFVEPVRIRAGVRFWNEHAD
CCCHHHHHHHHHHHHHCCCCCHHCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHH
TLARAEREYGVPASIIVGILGVETLYGQHMGSFRVMDALATLAFDFPAAHPRATERQAFF
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
RGELEQFLSLADRTGTDPFVLRGSYAGAMGMGQFMPTSWARWAVDFDGDGRIDLFNSTAD
HHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEECCHHH
AIGSVANYFQAHGWVSGLPTHYAVAFDDNGLRLPELLAPDILPTFTAAGMQERGARPLPA
HHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCHHHHCCHHHHHHHHHCHHHCCCCCCCC
DGAATQPDAAGPLALIELQNGNAPAAYVAGTRNFYVVTRYNWSSYYAMAVIDLGQEVSAA
CCCCCCCCCCCCEEEEEEECCCCCEEEEECCCCEEEEEEECCCCEEEEHEECCCCHHHCC
R
C
>Mature Secondary Structure 
PFARSTALLVLACAATMVLPPAAMAQKPARKKEKQAVPEVLYAQRPEALRFADDLAERR
CCCHHHHHHHHHHHHHHHCCCHHHHHCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
GLDREWVRQAIGQARFLPQVPRLMLPAPRGTAKNWAAYRARFVEPVRIRAGVRFWNEHAD
CCCHHHHHHHHHHHHHCCCCCHHCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHH
TLARAEREYGVPASIIVGILGVETLYGQHMGSFRVMDALATLAFDFPAAHPRATERQAFF
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
RGELEQFLSLADRTGTDPFVLRGSYAGAMGMGQFMPTSWARWAVDFDGDGRIDLFNSTAD
HHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEECCHHH
AIGSVANYFQAHGWVSGLPTHYAVAFDDNGLRLPELLAPDILPTFTAAGMQERGARPLPA
HHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCHHHHCCHHHHHHHHHCHHHCCCCCCCC
DGAATQPDAAGPLALIELQNGNAPAAYVAGTRNFYVVTRYNWSSYYAMAVIDLGQEVSAA
CCCCCCCCCCCCEEEEEEECCCCCEEEEECCCCEEEEEEECCCCEEEEHEECCCCHHHCC
R
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic Bond [C]

General reaction: Cleavage Bond [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7476170; 7789526; 9205837; 9278503; 3553176; 9761817; 10570954; 10545329; 10684641 [H]