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The map label for this gene is rhmA [H]

Identifier: 120610758

GI number: 120610758

Start: 2281919

End: 2282761

Strand: Reverse

Name: rhmA [H]

Synonym: Aave_2080

Alternate gene names: 120610758

Gene position: 2282761-2281919 (Counterclockwise)

Preceding gene: 120610759

Following gene: 120610756

Centisome position: 42.65

GC content: 70.7

Gene sequence:

>843_bases
ATGCCCACCCGCTCCCCGCATTCGACCGGAAACCCACCGATGCCCGCACACAACCCCTTCAAAGCGGCCCTCGCCGCCCG
CCAGCCGCAGATCGGCCTCTGGCTCTCCATGGCCGATCCCTACCTCGCCGAGGCGGCCGCGACCACTGGCTACGACTGGC
TGCTGATCGACGGCGAGCATGCGCCCAACGACCTGCGCAGCACCCTCGGCGCGCTGCAGGCCGTGGCGCCCTACCCTTCG
CAACCCGTGGTGCGCATCGCCGAAGGCAGCACGGCCCTCATCAAGCAGGTGCTGGACATCGGTGCGCGTACGCTGCTGGT
GCCGATGGTGGACACGCCCGAACAGGCCCGCGCCATCGCCGCCGCCACGCAGTACCCGCCGCATGGCATCCGGGGCGTGG
GCAGCGCCGTCGGCCGCGTGTCGCAATGGAGCGGCCGGGCGGACTACCTGGCCGTGGCCGACGACGAGGTCTGCCTGCTG
GTGCAGGCCGAGACGGTGACCGCACTGCGCAACCTGCCCGCGATCTGCGCGGTGGAGGGCGTGCACGGCATCTTCATCGG
GCCGGCGGATCTGGCGGCCTCCATGGGCCACCGCGGCAACCCCGGCCACCCGGAAGTGCAGGCCGCGATCGAGGACGCCA
TGCGCACCATCGTCGCGAGCGGCAAGGCCGCGGGCACGCTGACCTCGGACCCGGCCCTGGCACAGCGCTACCTGGATCTG
GGCTGCACTTTTGTGGCGGTGGGTGTGGATGTGCTGATGTTCGTGGGCGCGGCGCGAAAGCTGCGTGCTCAGTTCAGCGG
GGCGGGTGATACGGTGTCTGCAAAACCCAACGCGGCCTATTGA

Upstream 100 bases:

>100_bases
TCGGCGGCGTGAAGGAATCCGGCTACGGCCGCGAGGGCTCCACCCACGGCCTGGACGATTACCTGCACACCAAGTACCTT
TGCCAGGGCGGGCTCGACTG

Downstream 100 bases:

>100_bases
TCGAAGCCTGGAACGAATGGCCCGGCCTGCGAAAGGCGCCATGGTCGGGATACAGCCGTCACCGGAGTACCAACGCTGAT
CACGCGGAATTCCTCGTTTC

Product: 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase

Products: NA

Alternate protein names: KDR aldolase; 2-dehydro-3-deoxyrhamnonate aldolase [H]

Number of amino acids: Translated: 280; Mature: 279

Protein sequence:

>280_residues
MPTRSPHSTGNPPMPAHNPFKAALAARQPQIGLWLSMADPYLAEAAATTGYDWLLIDGEHAPNDLRSTLGALQAVAPYPS
QPVVRIAEGSTALIKQVLDIGARTLLVPMVDTPEQARAIAAATQYPPHGIRGVGSAVGRVSQWSGRADYLAVADDEVCLL
VQAETVTALRNLPAICAVEGVHGIFIGPADLAASMGHRGNPGHPEVQAAIEDAMRTIVASGKAAGTLTSDPALAQRYLDL
GCTFVAVGVDVLMFVGAARKLRAQFSGAGDTVSAKPNAAY

Sequences:

>Translated_280_residues
MPTRSPHSTGNPPMPAHNPFKAALAARQPQIGLWLSMADPYLAEAAATTGYDWLLIDGEHAPNDLRSTLGALQAVAPYPS
QPVVRIAEGSTALIKQVLDIGARTLLVPMVDTPEQARAIAAATQYPPHGIRGVGSAVGRVSQWSGRADYLAVADDEVCLL
VQAETVTALRNLPAICAVEGVHGIFIGPADLAASMGHRGNPGHPEVQAAIEDAMRTIVASGKAAGTLTSDPALAQRYLDL
GCTFVAVGVDVLMFVGAARKLRAQFSGAGDTVSAKPNAAY
>Mature_279_residues
PTRSPHSTGNPPMPAHNPFKAALAARQPQIGLWLSMADPYLAEAAATTGYDWLLIDGEHAPNDLRSTLGALQAVAPYPSQ
PVVRIAEGSTALIKQVLDIGARTLLVPMVDTPEQARAIAAATQYPPHGIRGVGSAVGRVSQWSGRADYLAVADDEVCLLV
QAETVTALRNLPAICAVEGVHGIFIGPADLAASMGHRGNPGHPEVQAAIEDAMRTIVASGKAAGTLTSDPALAQRYLDLG
CTFVAVGVDVLMFVGAARKLRAQFSGAGDTVSAKPNAAY

Specific function: Catalyzes the reversible retro-aldol cleavage of 2-keto- 3-deoxy-L-rhamnonate (KDR) to pyruvate and lactaldehyde [H]

COG id: COG3836

COG function: function code G; 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HpcH/HpaI aldolase family. KDR aldolase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788578, Length=249, Percent_Identity=57.8313253012048, Blast_Score=288, Evalue=3e-79,
Organism=Escherichia coli, GI1789514, Length=249, Percent_Identity=46.1847389558233, Blast_Score=224, Evalue=6e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005000
- InterPro:   IPR015813 [H]

Pfam domain/function: PF03328 HpcH_HpaI [H]

EC number: 4.1.2.-

Molecular weight: Translated: 29086; Mature: 28955

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTRSPHSTGNPPMPAHNPFKAALAARQPQIGLWLSMADPYLAEAAATTGYDWLLIDGEH
CCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEECCCCHHHHHHHCCCCEEEEECCCC
APNDLRSTLGALQAVAPYPSQPVVRIAEGSTALIKQVLDIGARTLLVPMVDTPEQARAIA
CCHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHCCCCEEEEECCCCHHHHHHHH
AATQYPPHGIRGVGSAVGRVSQWSGRADYLAVADDEVCLLVQAETVTALRNLPAICAVEG
HHCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCEEEEEEHHHHHHHHCCCCEEEECC
VHGIFIGPADLAASMGHRGNPGHPEVQAAIEDAMRTIVASGKAAGTLTSDPALAQRYLDL
CCEEEECHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
GCTFVAVGVDVLMFVGAARKLRAQFSGAGDTVSAKPNAAY
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCC
>Mature Secondary Structure 
PTRSPHSTGNPPMPAHNPFKAALAARQPQIGLWLSMADPYLAEAAATTGYDWLLIDGEH
CCCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEECCCCHHHHHHHCCCCEEEEECCCC
APNDLRSTLGALQAVAPYPSQPVVRIAEGSTALIKQVLDIGARTLLVPMVDTPEQARAIA
CCHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHCCCCEEEEECCCCHHHHHHHH
AATQYPPHGIRGVGSAVGRVSQWSGRADYLAVADDEVCLLVQAETVTALRNLPAICAVEG
HHCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCEEEEEEHHHHHHHHCCCCEEEECC
VHGIFIGPADLAASMGHRGNPGHPEVQAAIEDAMRTIVASGKAAGTLTSDPALAQRYLDL
CCEEEECHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
GCTFVAVGVDVLMFVGAARKLRAQFSGAGDTVSAKPNAAY
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA