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The map label for this gene is suhB [H]

Identifier: 120610748

GI number: 120610748

Start: 2271301

End: 2272242

Strand: Reverse

Name: suhB [H]

Synonym: Aave_2070

Alternate gene names: 120610748

Gene position: 2272242-2271301 (Counterclockwise)

Preceding gene: 120610749

Following gene: 120610747

Centisome position: 42.45

GC content: 68.47

Gene sequence:

>942_bases
ATGTCGTCCAATCTGCACCCCATGCTCAACGTGGCCATCAAGGCCGCTCGCGCCGCAGGCGCCATCATCAACCGCGCGGC
GCTCGACGTCGAGGCGGTGCGCGTTTCGCAGAAGCAGATCAACGACTTCGTGACCGAGGTGGACCACGCGAGCGAACAGG
CCATCATCGAGACCCTGCTCACCGCCTACCCGGGCCACGGCATCCTCGCCGAGGAATCGGGCAGCCAGTACGGCGCGAAG
GATTCGGAATTCATCTGGGTCATCGACCCGCTGGACGGCACGACCAACTTCATCCACGGCTTTCCCGTCTATTGCGTGAG
CATCGCGCTCATGGTGCGCGGCAAGGTCGAGCAGGCCGTCATCTACGACCCCACCCGCAACGACCTCTTCACGGCCACCA
AGGGTCGCGGCGCCTACCTGAACGAGCGCCGCATCCGGGTGTCCAAGCGCACCCAGCTCAAGGAAAGCCTGCTGTCCACC
GGCTTCCCGTTCCGCCCGGGCGACAACTTCAAGACCTACCTGCACATCATGTCCGACGTGATGCAGCGCACGGCCGGCCT
GCGCCGCCCCGGCGCGGCCGCGCTGGACCTCGCCTACGTGGCGGCCGGCTTCACCGAAGGCTTCTTCGAGACGGGCCTGT
CCATCTGGGACGTGGCGGCCGGCTCGCTGCTGGTGACCGAGGCCGGCGGCCTGGTGGGCAACTTCACGGGCGAGGCCGAC
TTCCTGGAGCAGCGCGAGTGCCTGGCGGCCACGCCGCGCATCTACGGCCAGCTGGTGCCGATCCTCTGCAGGTACAGCAA
GTTCGCCAGCGCGGGCGACAAGGCCGCCGTGCGGCAGGCCGTGCGCAACGACACGCCGGCCGGCGAGGCCCTCGCGGAGC
CCGTGGAATCGCAGGCAACGGACACGGAAGGCAGCGAAGAGGCGCCGCGCGCGCCGTTCTGA

Upstream 100 bases:

>100_bases
GAAATCCGGCAAGGGCGCTAAAATACCCGGCCATCACGTCCGCATCGCCGGGCGATCCCCCTTGCCGCCCCCTGCGGCGC
CAGCTCCTTCCTCACAATTC

Downstream 100 bases:

>100_bases
ACGGCCTTCGCCCCCCGGGCAGCCCCATCGCTGGCGGGGGCTCCGGCACGGCTGAGTTCGCGGTTTCTGGCAGCATCCGG
AAAGCCGCCACCCTCCTCCG

Product: inositol monophosphatase

Products: NA

Alternate protein names: I-1-Pase; IMPase; Inositol-1-phosphatase [H]

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MSSNLHPMLNVAIKAARAAGAIINRAALDVEAVRVSQKQINDFVTEVDHASEQAIIETLLTAYPGHGILAEESGSQYGAK
DSEFIWVIDPLDGTTNFIHGFPVYCVSIALMVRGKVEQAVIYDPTRNDLFTATKGRGAYLNERRIRVSKRTQLKESLLST
GFPFRPGDNFKTYLHIMSDVMQRTAGLRRPGAAALDLAYVAAGFTEGFFETGLSIWDVAAGSLLVTEAGGLVGNFTGEAD
FLEQRECLAATPRIYGQLVPILCRYSKFASAGDKAAVRQAVRNDTPAGEALAEPVESQATDTEGSEEAPRAPF

Sequences:

>Translated_313_residues
MSSNLHPMLNVAIKAARAAGAIINRAALDVEAVRVSQKQINDFVTEVDHASEQAIIETLLTAYPGHGILAEESGSQYGAK
DSEFIWVIDPLDGTTNFIHGFPVYCVSIALMVRGKVEQAVIYDPTRNDLFTATKGRGAYLNERRIRVSKRTQLKESLLST
GFPFRPGDNFKTYLHIMSDVMQRTAGLRRPGAAALDLAYVAAGFTEGFFETGLSIWDVAAGSLLVTEAGGLVGNFTGEAD
FLEQRECLAATPRIYGQLVPILCRYSKFASAGDKAAVRQAVRNDTPAGEALAEPVESQATDTEGSEEAPRAPF
>Mature_312_residues
SSNLHPMLNVAIKAARAAGAIINRAALDVEAVRVSQKQINDFVTEVDHASEQAIIETLLTAYPGHGILAEESGSQYGAKD
SEFIWVIDPLDGTTNFIHGFPVYCVSIALMVRGKVEQAVIYDPTRNDLFTATKGRGAYLNERRIRVSKRTQLKESLLSTG
FPFRPGDNFKTYLHIMSDVMQRTAGLRRPGAAALDLAYVAAGFTEGFFETGLSIWDVAAGSLLVTEAGGLVGNFTGEADF
LEQRECLAATPRIYGQLVPILCRYSKFASAGDKAAVRQAVRNDTPAGEALAEPVESQATDTEGSEEAPRAPF

Specific function: Unknown

COG id: COG0483

COG function: function code G; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI7657236, Length=257, Percent_Identity=37.7431906614786, Blast_Score=154, Evalue=8e-38,
Organism=Homo sapiens, GI5031789, Length=264, Percent_Identity=32.9545454545455, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI221625487, Length=264, Percent_Identity=32.9545454545455, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI221625507, Length=153, Percent_Identity=33.9869281045752, Blast_Score=100, Evalue=2e-21,
Organism=Escherichia coli, GI1788882, Length=250, Percent_Identity=51.6, Blast_Score=257, Evalue=6e-70,
Organism=Escherichia coli, GI1790659, Length=150, Percent_Identity=31.3333333333333, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI193202572, Length=252, Percent_Identity=35.3174603174603, Blast_Score=148, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI193202570, Length=253, Percent_Identity=35.5731225296443, Blast_Score=145, Evalue=4e-35,
Organism=Saccharomyces cerevisiae, GI6320493, Length=220, Percent_Identity=38.6363636363636, Blast_Score=139, Evalue=5e-34,
Organism=Saccharomyces cerevisiae, GI6321836, Length=225, Percent_Identity=34.2222222222222, Blast_Score=116, Evalue=4e-27,
Organism=Drosophila melanogaster, GI21357303, Length=258, Percent_Identity=35.2713178294574, Blast_Score=160, Evalue=1e-39,
Organism=Drosophila melanogaster, GI21357329, Length=273, Percent_Identity=34.4322344322344, Blast_Score=152, Evalue=3e-37,
Organism=Drosophila melanogaster, GI24664922, Length=270, Percent_Identity=32.2222222222222, Blast_Score=140, Evalue=8e-34,
Organism=Drosophila melanogaster, GI21357957, Length=248, Percent_Identity=31.0483870967742, Blast_Score=117, Evalue=7e-27,
Organism=Drosophila melanogaster, GI24664926, Length=220, Percent_Identity=30, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24664918, Length=239, Percent_Identity=30.1255230125523, Blast_Score=108, Evalue=6e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550
- InterPro:   IPR022337 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.25 [H]

Molecular weight: Translated: 33821; Mature: 33689

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS00629 IMP_1 ; PS00630 IMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSNLHPMLNVAIKAARAAGAIINRAALDVEAVRVSQKQINDFVTEVDHASEQAIIETLL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
TAYPGHGILAEESGSQYGAKDSEFIWVIDPLDGTTNFIHGFPVYCVSIALMVRGKVEQAV
HHCCCCCEEECCCCCCCCCCCCCEEEEEECCCCCCHHHCCHHHHHHHHHHHHHCCCCCEE
IYDPTRNDLFTATKGRGAYLNERRIRVSKRTQLKESLLSTGFPFRPGDNFKTYLHIMSDV
EECCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
MQRTAGLRRPGAAALDLAYVAAGFTEGFFETGLSIWDVAAGSLLVTEAGGLVGNFTGEAD
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCEEEEECCCCEECCCCCHH
FLEQRECLAATPRIYGQLVPILCRYSKFASAGDKAAVRQAVRNDTPAGEALAEPVESQAT
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCC
DTEGSEEAPRAPF
CCCCCCCCCCCCC
>Mature Secondary Structure 
SSNLHPMLNVAIKAARAAGAIINRAALDVEAVRVSQKQINDFVTEVDHASEQAIIETLL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
TAYPGHGILAEESGSQYGAKDSEFIWVIDPLDGTTNFIHGFPVYCVSIALMVRGKVEQAV
HHCCCCCEEECCCCCCCCCCCCCEEEEEECCCCCCHHHCCHHHHHHHHHHHHHCCCCCEE
IYDPTRNDLFTATKGRGAYLNERRIRVSKRTQLKESLLSTGFPFRPGDNFKTYLHIMSDV
EECCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
MQRTAGLRRPGAAALDLAYVAAGFTEGFFETGLSIWDVAAGSLLVTEAGGLVGNFTGEAD
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCEEEEECCCCEECCCCCHH
FLEQRECLAATPRIYGQLVPILCRYSKFASAGDKAAVRQAVRNDTPAGEALAEPVESQAT
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCC
DTEGSEEAPRAPF
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]