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The map label for this gene is foxA [H]

Identifier: 120610732

GI number: 120610732

Start: 2249307

End: 2251418

Strand: Reverse

Name: foxA [H]

Synonym: Aave_2054

Alternate gene names: 120610732

Gene position: 2251418-2249307 (Counterclockwise)

Preceding gene: 120610733

Following gene: 120610731

Centisome position: 42.06

GC content: 71.97

Gene sequence:

>2112_bases
ATGCGGAACATCGGTCTGGCGCTGCTGCTGGGCAGCACGGGCGCCCCGGCGCAGGAAGGGCCTGCCCCCGCGCCCACCCT
GGGCACGGTGGAAGTCCGGGCCGAGCGCGCGGCGCCCGGCAGCTCGCTGGGGCTGGACATCCCGCAGGACGTGGGCTCCC
GCCTGGGCCTCACGCCCCGCGAGACTCCCGCCAGCGTCAGCGCCATGGACGCGGAGGACATCGCCGGCCGCGACCTCACC
CGCGCCCAGGATGTCGCCACGCGCATGCCGGGCATCACCGAATCGCCGGCGCCGGGCAATGGCGGCACATCGCTGTCCGC
ACGGGGCTTCGTGGGGCACAACTCCGTCGCCCAGCTGATCGACGGAACGCGTCTGGCCGTCGCCGCGGGCACCGTGACCT
ACCCGTTCTCCACCTGGCCGCTGGCCTCGGTCGAAGTCCTGCGCGGGCCCGCGTCGGTGCTGTACGGCGACGGGGCCATC
GGCGCGGCGGTGAACTACGTCACGCGCAAGCCCGCCTGGAACCGGACGCACCGCGAGGCATTCCTGACAGCGGGCTCGCA
TGGGCAACGGCAGGGCGGCGTCGGCTTGCGCGGCCCCGTCAACGACGCCGCCGCCTACTCGGTCTATCTCGACGCCGCCG
GCGGCGACGGCTACCGGGCACTGGAGGAAGTGGAGCGCCGCAACTACGCGCTGGCACTGTCCGTCAGGCCCGCGTCCGGA
CTGGCGGCCACCTTCTCGCTGGACGGCGGAATGAACGACGATGCGCGCTACTTCGGTACACCGCTGCGCGGCGGAAGCTT
CGACGACCGGGTACGACGCATCAACTACAACGTTTCGGACGCGGTCGTGCGCTACGACGACCGGCTCTGGCGCGCGAAGG
TGGAATACCGTGCCGGCCCGGACGTGCGGCTGCGCAACGAGACCTACCACGCGACCTCGGAGCGCCACTGGCGCAACGCC
GAATCCTATGGCTTCGACCGCACCGGCGGCTCCGTCATCCGCTCGGACTACCTGGAGATCCTGCACGACCTGCAGCAGAC
CGGCAACCGGCTGGACGTGAGCATCGACGGCTCGGTCGCCGGCCTTCCGAACCGCTTCGTCGCCGGCGTGGACTGGCACC
GCACCAGGCTCCTGCACACCAACAATGCACCCTACCGCGGGGCCAGTGCGGTCGATCCCTACGCCTTCGACCCCGGCGTC
TTCGACAGCCCCGACCCCACCAAGCCCGGGCGGCAGGCCCGGCTGCGGACGACCGCGCTCTACGCCGAGAACGCCCTGGA
CCTGGCCCCGCGATGGAAGCTGGTGGGCGGACTGCGCCACGAGCGCACCAGGCTCGATGACGACAACCTGCGAACGGCCG
TGCGCCAGCGCAAATCCTACGCCCCCACGACGGGCCGGATCGGCCTGGTGTGGACGGCCAGCGAGACCCTGTCTTTCTAC
GGCCAGTACGCCACCGGCACCGATCCGCTGAGCGGCGCGCTGTCCCTGCCCGGCGGCGGCACGGTCTTCGACCTGACCCG
CGGGCGGCAGGCCGAGGTGGGCGCCAAAGGCCTGCTGCCCGCCATCCGCGGCGAGTGGACCGCCGCGGCTTACCGGATCG
ACAAACGCCACCTGCTCTCGCGCGATCCCGACGAGCCGGGCGTCGTCCGGCAGGTCGGGCACCAGTCCTCCACCGGGCTC
GAACTGGCGTTCGCCGCGGAACCGGTGTCCGGCTGGACCGTGGACGCCAATGCCGCATGGCTGCGGGCCCGCTATGAGGA
CTTCGACGAGGCGAGCGGCGGCACGGCGGTATCGCGACGCGGGAACGTGCCGGTCGGCGTGCCGGAGCGCACGGCCCATC
TCTGGACCACCTACCGCCTCGCCCCCCGATGGCGTGCCGGCGCGGGACTGCGCTATGTCGGTGCGCGGTTCACCAACGCG
GCGAACTCGGGCCGGTTGCCCGGCTACACCGTGGCCGATGCTTCGCTGGCGTACGAGCATTCCTCCGCGCTGCGGCTCAT
GCTGTCGGTACGGAACCTGGCCGATCGCACGTATCCGGTGTCCGGCTCCGGTTCGACCTGGCTGCTGGGAGCGCCGAGGA
CCGTGCAACTGACCCTCCGCGCGACGTTCTGA

Upstream 100 bases:

>100_bases
CGCCTGGCGGGCTTCAGCTCCATGGCGCTGTGGACGGGCGTGGTCGTCCTCGGCCGCTGGATCGGCTTCGTCTGATTCCC
CGCGGGACGGCGGAAACGGC

Downstream 100 bases:

>100_bases
CCCGCCGTGGCACCCGCCTCCCTCAAGCCAGGCCTGGCCTGGCTGCACAAATGGCTCGGCATTCCGCTGGCGCTGCTCTT
CTCCATGTGGTTCGCCAGCG

Product: TonB-dependent siderophore receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 703; Mature: 703

Protein sequence:

>703_residues
MRNIGLALLLGSTGAPAQEGPAPAPTLGTVEVRAERAAPGSSLGLDIPQDVGSRLGLTPRETPASVSAMDAEDIAGRDLT
RAQDVATRMPGITESPAPGNGGTSLSARGFVGHNSVAQLIDGTRLAVAAGTVTYPFSTWPLASVEVLRGPASVLYGDGAI
GAAVNYVTRKPAWNRTHREAFLTAGSHGQRQGGVGLRGPVNDAAAYSVYLDAAGGDGYRALEEVERRNYALALSVRPASG
LAATFSLDGGMNDDARYFGTPLRGGSFDDRVRRINYNVSDAVVRYDDRLWRAKVEYRAGPDVRLRNETYHATSERHWRNA
ESYGFDRTGGSVIRSDYLEILHDLQQTGNRLDVSIDGSVAGLPNRFVAGVDWHRTRLLHTNNAPYRGASAVDPYAFDPGV
FDSPDPTKPGRQARLRTTALYAENALDLAPRWKLVGGLRHERTRLDDDNLRTAVRQRKSYAPTTGRIGLVWTASETLSFY
GQYATGTDPLSGALSLPGGGTVFDLTRGRQAEVGAKGLLPAIRGEWTAAAYRIDKRHLLSRDPDEPGVVRQVGHQSSTGL
ELAFAAEPVSGWTVDANAAWLRARYEDFDEASGGTAVSRRGNVPVGVPERTAHLWTTYRLAPRWRAGAGLRYVGARFTNA
ANSGRLPGYTVADASLAYEHSSALRLMLSVRNLADRTYPVSGSGSTWLLGAPRTVQLTLRATF

Sequences:

>Translated_703_residues
MRNIGLALLLGSTGAPAQEGPAPAPTLGTVEVRAERAAPGSSLGLDIPQDVGSRLGLTPRETPASVSAMDAEDIAGRDLT
RAQDVATRMPGITESPAPGNGGTSLSARGFVGHNSVAQLIDGTRLAVAAGTVTYPFSTWPLASVEVLRGPASVLYGDGAI
GAAVNYVTRKPAWNRTHREAFLTAGSHGQRQGGVGLRGPVNDAAAYSVYLDAAGGDGYRALEEVERRNYALALSVRPASG
LAATFSLDGGMNDDARYFGTPLRGGSFDDRVRRINYNVSDAVVRYDDRLWRAKVEYRAGPDVRLRNETYHATSERHWRNA
ESYGFDRTGGSVIRSDYLEILHDLQQTGNRLDVSIDGSVAGLPNRFVAGVDWHRTRLLHTNNAPYRGASAVDPYAFDPGV
FDSPDPTKPGRQARLRTTALYAENALDLAPRWKLVGGLRHERTRLDDDNLRTAVRQRKSYAPTTGRIGLVWTASETLSFY
GQYATGTDPLSGALSLPGGGTVFDLTRGRQAEVGAKGLLPAIRGEWTAAAYRIDKRHLLSRDPDEPGVVRQVGHQSSTGL
ELAFAAEPVSGWTVDANAAWLRARYEDFDEASGGTAVSRRGNVPVGVPERTAHLWTTYRLAPRWRAGAGLRYVGARFTNA
ANSGRLPGYTVADASLAYEHSSALRLMLSVRNLADRTYPVSGSGSTWLLGAPRTVQLTLRATF
>Mature_703_residues
MRNIGLALLLGSTGAPAQEGPAPAPTLGTVEVRAERAAPGSSLGLDIPQDVGSRLGLTPRETPASVSAMDAEDIAGRDLT
RAQDVATRMPGITESPAPGNGGTSLSARGFVGHNSVAQLIDGTRLAVAAGTVTYPFSTWPLASVEVLRGPASVLYGDGAI
GAAVNYVTRKPAWNRTHREAFLTAGSHGQRQGGVGLRGPVNDAAAYSVYLDAAGGDGYRALEEVERRNYALALSVRPASG
LAATFSLDGGMNDDARYFGTPLRGGSFDDRVRRINYNVSDAVVRYDDRLWRAKVEYRAGPDVRLRNETYHATSERHWRNA
ESYGFDRTGGSVIRSDYLEILHDLQQTGNRLDVSIDGSVAGLPNRFVAGVDWHRTRLLHTNNAPYRGASAVDPYAFDPGV
FDSPDPTKPGRQARLRTTALYAENALDLAPRWKLVGGLRHERTRLDDDNLRTAVRQRKSYAPTTGRIGLVWTASETLSFY
GQYATGTDPLSGALSLPGGGTVFDLTRGRQAEVGAKGLLPAIRGEWTAAAYRIDKRHLLSRDPDEPGVVRQVGHQSSTGL
ELAFAAEPVSGWTVDANAAWLRARYEDFDEASGGTAVSRRGNVPVGVPERTAHLWTTYRLAPRWRAGAGLRYVGARFTNA
ANSGRLPGYTVADASLAYEHSSALRLMLSVRNLADRTYPVSGSGSTWLLGAPRTVQLTLRATF

Specific function: Ferrioxamine binding and uptake, in association with the tonB protein. May play a role in intestinal colonization [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1786344, Length=764, Percent_Identity=22.5130890052356, Blast_Score=95, Evalue=2e-20,
Organism=Escherichia coli, GI1787024, Length=324, Percent_Identity=26.2345679012346, Blast_Score=78, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 75522; Mature: 75522

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: PS00178 AA_TRNA_LIGASE_I ; PS01156 TONB_DEPENDENT_REC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNIGLALLLGSTGAPAQEGPAPAPTLGTVEVRAERAAPGSSLGLDIPQDVGSRLGLTPR
CCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHCCCCCC
ETPASVSAMDAEDIAGRDLTRAQDVATRMPGITESPAPGNGGTSLSARGFVGHNSVAQLI
CCCCCEEECCHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCCHHHHHH
DGTRLAVAAGTVTYPFSTWPLASVEVLRGPASVLYGDGAIGAAVNYVTRKPAWNRTHREA
CCCEEEEEECEEECCCCCCCCCHHHHHCCCCCEEECCCCHHHHHHHHHCCCCCCCCHHHH
FLTAGSHGQRQGGVGLRGPVNDAAAYSVYLDAAGGDGYRALEEVERRNYALALSVRPASG
EEECCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHCCEEEEEEECCCCC
LAATFSLDGGMNDDARYFGTPLRGGSFDDRVRRINYNVSDAVVRYDDRLWRAKVEYRAGP
EEEEEEECCCCCCCHHHCCCCCCCCCHHHHHEEECCCHHHHEEEECCCEEEEEEEECCCC
DVRLRNETYHATSERHWRNAESYGFDRTGGSVIRSDYLEILHDLQQTGNRLDVSIDGSVA
CEEECCCCEECCCHHHCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCC
GLPNRFVAGVDWHRTRLLHTNNAPYRGASAVDPYAFDPGVFDSPDPTKPGRQARLRTTAL
CCCCHHEECCCHHEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHEEEEEE
YAENALDLAPRWKLVGGLRHERTRLDDDNLRTAVRQRKSYAPTTGRIGLVWTASETLSFY
ECCCCCCCCCCHHHHCCCHHHHCCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHH
GQYATGTDPLSGALSLPGGGTVFDLTRGRQAEVGAKGLLPAIRGEWTAAAYRIDKRHLLS
CCCCCCCCCCCCEEECCCCCEEEEECCCCCCCCCCCCCCHHHCCCCCCEEEEECHHHHHC
RDPDEPGVVRQVGHQSSTGLELAFAAEPVSGWTVDANAAWLRARYEDFDEASGGTAVSRR
CCCCCCCHHHHHCCCCCCCEEEEEEECCCCCEEECCCCCEEHHHHHHHHCCCCCCEEECC
GNVPVGVPERTAHLWTTYRLAPRWRAGAGLRYVGARFTNAANSGRLPGYTVADASLAYEH
CCCCCCCCCCCEEEEEEEEECCCCCCCCCEEEECHHHCCCCCCCCCCCEEEECCHHHHHH
SSALRLMLSVRNLADRTYPVSGSGSTWLLGAPRTVQLTLRATF
HHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCEEEEEEEECC
>Mature Secondary Structure
MRNIGLALLLGSTGAPAQEGPAPAPTLGTVEVRAERAAPGSSLGLDIPQDVGSRLGLTPR
CCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHCCCCCC
ETPASVSAMDAEDIAGRDLTRAQDVATRMPGITESPAPGNGGTSLSARGFVGHNSVAQLI
CCCCCEEECCHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCCHHHHHH
DGTRLAVAAGTVTYPFSTWPLASVEVLRGPASVLYGDGAIGAAVNYVTRKPAWNRTHREA
CCCEEEEEECEEECCCCCCCCCHHHHHCCCCCEEECCCCHHHHHHHHHCCCCCCCCHHHH
FLTAGSHGQRQGGVGLRGPVNDAAAYSVYLDAAGGDGYRALEEVERRNYALALSVRPASG
EEECCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHCCEEEEEEECCCCC
LAATFSLDGGMNDDARYFGTPLRGGSFDDRVRRINYNVSDAVVRYDDRLWRAKVEYRAGP
EEEEEEECCCCCCCHHHCCCCCCCCCHHHHHEEECCCHHHHEEEECCCEEEEEEEECCCC
DVRLRNETYHATSERHWRNAESYGFDRTGGSVIRSDYLEILHDLQQTGNRLDVSIDGSVA
CEEECCCCEECCCHHHCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCC
GLPNRFVAGVDWHRTRLLHTNNAPYRGASAVDPYAFDPGVFDSPDPTKPGRQARLRTTAL
CCCCHHEECCCHHEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHEEEEEE
YAENALDLAPRWKLVGGLRHERTRLDDDNLRTAVRQRKSYAPTTGRIGLVWTASETLSFY
ECCCCCCCCCCHHHHCCCHHHHCCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHH
GQYATGTDPLSGALSLPGGGTVFDLTRGRQAEVGAKGLLPAIRGEWTAAAYRIDKRHLLS
CCCCCCCCCCCCEEECCCCCEEEEECCCCCCCCCCCCCCHHHCCCCCCEEEEECHHHHHC
RDPDEPGVVRQVGHQSSTGLELAFAAEPVSGWTVDANAAWLRARYEDFDEASGGTAVSRR
CCCCCCCHHHHHCCCCCCCEEEEEEECCCCCEEECCCCCEEHHHHHHHHCCCCCCEEECC
GNVPVGVPERTAHLWTTYRLAPRWRAGAGLRYVGARFTNAANSGRLPGYTVADASLAYEH
CCCCCCCCCCCEEEEEEEEECCCCCCCCCEEEECHHHCCCCCCCCCCCEEEECCHHHHHH
SSALRLMLSVRNLADRTYPVSGSGSTWLLGAPRTVQLTLRATF
HHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677609; 10103258; 7642488 [H]