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The map label for this gene is thrB [H]

Identifier: 120610608

GI number: 120610608

Start: 2090040

End: 2091014

Strand: Reverse

Name: thrB [H]

Synonym: Aave_1928

Alternate gene names: 120610608

Gene position: 2091014-2090040 (Counterclockwise)

Preceding gene: 120610609

Following gene: 120610607

Centisome position: 39.06

GC content: 70.67

Gene sequence:

>975_bases
ATGGCCGTTTTCACCGAAGTCTCCAAGAAAGAGGCGCGCGATCTGCTGCGCCGTTTGCAGCTGGGCACCCTGGAGTCGCT
GCGCGGCATCGAAGGCGGCATCGAGAACACGAACTACTTCCTCACCAGCGACCAGGGCGAGTACGTGCTCACGCTGTTCG
AGCGCCTGACCGCCGAGCAGTTGCCGTTCTACCTGCACCTGATGAAGCACCTCGCGCAGGCGGGGATTCCCGTGCCGGAC
CCGCGCGGCGACCGCCATGGGAACATCCTGCACTCCGTCGCGGGCAAGCCCGCCGCCGTGGTGAACAAGTTGCCCGGCAG
GAGCCAGCTCGCGCCCGGGCCGGTGCACTGCGCGGCGGTGGGCGGCATGCTGGCCCGCATGCATCTGGCCGGCCGGGACT
ACGAGCGCCGGCAGCCCAACCTGCGCGGCCTGGCCTGGTGGAACGAGACGGTGCCCGTGGTGCTGCCCCACATCGGCGAG
GCCCAGCGCACCCTGCTGCGCTCCGAACTGGCCTACCAGAACCATGTCGCCGCCTCCGCGGGCTACGCGGCGCTGCCGCG
CGGCCCGGTCCATGCCGACCTGTTCCGCGACAACGCGATGTTCGACGGCGAGGCCCTGACCGGCTTCTTCGACTTCTATT
TCGCGGGCGTGGACACCTGGCTGTTCGACCTGGCGGTGTGCCTGAACGACTGGTGCATCGACTGGCCCACCGGTCTCCAC
GAATCCGGGCGCGCCGCGGCCATGCTGGATGCCTACCAGGCGGTGCGACCGCTGTCGGCCGACGAGCGGGCCCTGCTGCC
CGCGATGCTGCGCGCCGGCGCGCTGCGCTTCTGGATCTCCCGGCTGTGGGATTTCCACCTGCCGCGCGAGGCCAGCCTGC
TCACGCCGCACGATCCGGCGCACTTCGAGCGGGTGCTGCGCGGCCGCATCGCCCGGCCGCTGCATGCGCGCGCGGGCGGC
GGATTCGAGGAATGA

Upstream 100 bases:

>100_bases
GGGCACGGCATCCTCCCCGCAGGGCGCCTGCCGCGCCGTCCGGCCCCGGCTGCCTTCCCGCCCTTTTCTTTCGTCTTTCC
GCTCTTCTCCCCGCCAAGCA

Downstream 100 bases:

>100_bases
GCGCACCGGCCGCCGGCCACCGTGGCGGCGCGGCCACATGAAACCCGCCGGCGCGCCCGGAAACCCGCGCCCGCCCGGCC
CATCCGTCCCTTCGGCGCGA

Product: homoserine kinase

Products: NA

Alternate protein names: HK; HSK [H]

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MAVFTEVSKKEARDLLRRLQLGTLESLRGIEGGIENTNYFLTSDQGEYVLTLFERLTAEQLPFYLHLMKHLAQAGIPVPD
PRGDRHGNILHSVAGKPAAVVNKLPGRSQLAPGPVHCAAVGGMLARMHLAGRDYERRQPNLRGLAWWNETVPVVLPHIGE
AQRTLLRSELAYQNHVAASAGYAALPRGPVHADLFRDNAMFDGEALTGFFDFYFAGVDTWLFDLAVCLNDWCIDWPTGLH
ESGRAAAMLDAYQAVRPLSADERALLPAMLRAGALRFWISRLWDFHLPREASLLTPHDPAHFERVLRGRIARPLHARAGG
GFEE

Sequences:

>Translated_324_residues
MAVFTEVSKKEARDLLRRLQLGTLESLRGIEGGIENTNYFLTSDQGEYVLTLFERLTAEQLPFYLHLMKHLAQAGIPVPD
PRGDRHGNILHSVAGKPAAVVNKLPGRSQLAPGPVHCAAVGGMLARMHLAGRDYERRQPNLRGLAWWNETVPVVLPHIGE
AQRTLLRSELAYQNHVAASAGYAALPRGPVHADLFRDNAMFDGEALTGFFDFYFAGVDTWLFDLAVCLNDWCIDWPTGLH
ESGRAAAMLDAYQAVRPLSADERALLPAMLRAGALRFWISRLWDFHLPREASLLTPHDPAHFERVLRGRIARPLHARAGG
GFEE
>Mature_323_residues
AVFTEVSKKEARDLLRRLQLGTLESLRGIEGGIENTNYFLTSDQGEYVLTLFERLTAEQLPFYLHLMKHLAQAGIPVPDP
RGDRHGNILHSVAGKPAAVVNKLPGRSQLAPGPVHCAAVGGMLARMHLAGRDYERRQPNLRGLAWWNETVPVVLPHIGEA
QRTLLRSELAYQNHVAASAGYAALPRGPVHADLFRDNAMFDGEALTGFFDFYFAGVDTWLFDLAVCLNDWCIDWPTGLHE
SGRAAAMLDAYQAVRPLSADERALLPAMLRAGALRFWISRLWDFHLPREASLLTPHDPAHFERVLRGRIARPLHARAGGG
FEE

Specific function: Unknown

COG id: COG2334

COG function: function code R; Putative homoserine kinase type II (protein kinase fold)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pseudomonas-type thrB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002575
- InterPro:   IPR005280
- InterPro:   IPR011009 [H]

Pfam domain/function: PF01636 APH [H]

EC number: =2.7.1.39 [H]

Molecular weight: Translated: 36037; Mature: 35905

Theoretical pI: Translated: 7.23; Mature: 7.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVFTEVSKKEARDLLRRLQLGTLESLRGIEGGIENTNYFLTSDQGEYVLTLFERLTAEQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHH
LPFYLHLMKHLAQAGIPVPDPRGDRHGNILHSVAGKPAAVVNKLPGRSQLAPGPVHCAAV
CHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCHHHHHCCCCCCCCCCCCHHHHHH
GGMLARMHLAGRDYERRQPNLRGLAWWNETVPVVLPHIGEAQRTLLRSELAYQNHVAASA
HHHHHHHHHHCCCHHHCCCCCCEEEEECCCCCEEECCCCHHHHHHHHHHHHHHHHHHHCC
GYAALPRGPVHADLFRDNAMFDGEALTGFFDFYFAGVDTWLFDLAVCLNDWCIDWPTGLH
CCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
ESGRAAAMLDAYQAVRPLSADERALLPAMLRAGALRFWISRLWDFHLPREASLLTPHDPA
CCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHH
HFERVLRGRIARPLHARAGGGFEE
HHHHHHHHHHCCCHHHCCCCCCCC
>Mature Secondary Structure 
AVFTEVSKKEARDLLRRLQLGTLESLRGIEGGIENTNYFLTSDQGEYVLTLFERLTAEQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHH
LPFYLHLMKHLAQAGIPVPDPRGDRHGNILHSVAGKPAAVVNKLPGRSQLAPGPVHCAAV
CHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCHHHHHCCCCCCCCCCCCHHHHHH
GGMLARMHLAGRDYERRQPNLRGLAWWNETVPVVLPHIGEAQRTLLRSELAYQNHVAASA
HHHHHHHHHHCCCHHHCCCCCCEEEEECCCCCEEECCCCHHHHHHHHHHHHHHHHHHHCC
GYAALPRGPVHADLFRDNAMFDGEALTGFFDFYFAGVDTWLFDLAVCLNDWCIDWPTGLH
CCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
ESGRAAAMLDAYQAVRPLSADERALLPAMLRAGALRFWISRLWDFHLPREASLLTPHDPA
CCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHH
HFERVLRGRIARPLHARAGGGFEE
HHHHHHHHHHCCCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA