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The map label for this gene is nudL [H]

Identifier: 120610568

GI number: 120610568

Start: 2043615

End: 2044340

Strand: Direct

Name: nudL [H]

Synonym: Aave_1888

Alternate gene names: 120610568

Gene position: 2043615-2044340 (Clockwise)

Preceding gene: 120610567

Following gene: 120610569

Centisome position: 38.18

GC content: 71.63

Gene sequence:

>726_bases
ATGTCCTCTTCCCCATCCACCGCGGCCGCAGCCACTGCCGGGCCGCTGACGGCCCTGCCAGGATTCGATCCCCGGACGGT
TCCGGTGCTGGGGACCGACGCCCACCTGCCCGCCGTGCCGGCCGCTGCGTGGGCGCCCGAGGCGCTGCGCCGGCGCTTCG
CCGCGCCGCCGTCCTGGACGCCCGACGTGCTGCGCGAGAGGGCCATGACGACCCGCGCGCCGCGCGATGCGGCCGTGCTG
CTGGCGATCATGCTGCGCGATGAGCCGACCGTGCTGCTGACGGAGCGCACCGCGCATCTGTCCAACCATTCGGGGCAGGT
GGCCTTCCCGGGCGGACGCGTCGATCCGGGCGATGCGGACGCCGCTGCCGCCGCGCTGCGCGAGGCGCGCGAAGAAGTGG
GCCTCGACAGCGGCAGGGCGGAGGTGCTGGGCACGCTGCCCGTCTATGCCACCGGCACGGCCTTCCTCGTCACGCCCGTG
GTGGCGCTGGTCCAACCGGAAGGCAGCTTCCAACCCAATCCTTATGAAGTGGCCGATATCTTCGAGGTGCCGCTGGCCTT
CCTGCTGGACCCGTCGAACCACCGGCGCCATGCCCTCGACATCGGCGGTGCCCTGCGCGAGTGGTTCTCCATGCCCTACA
CCGATCCGGCGACGGGCAAGGACCACTTCATCTGGGGTGCCACGGCGGGCATGCTGCGCAATTTCTACCGCTTCCTGCTG
GCCTGA

Upstream 100 bases:

>100_bases
CCGAAGCCGCTACAGGGTCCTGTAGCGGCTTTTTTCTTGGCCGCCGCGCTGCGCCCCCGGGGCGCGCGCATTTATCTGCC
CACGCCGTAGGACCCGACGC

Downstream 100 bases:

>100_bases
GCCGGCGGCGTGCCGGTAGCGGGTCGGCCGCAATGTTTCCTGTGGTTACGGCCCAGTATGATTGCCGGCATGAGCTTCTT
TGCCATCCTCATGGCGTTGC

Product: NUDIX hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 241; Mature: 240

Protein sequence:

>241_residues
MSSSPSTAAAATAGPLTALPGFDPRTVPVLGTDAHLPAVPAAAWAPEALRRRFAAPPSWTPDVLRERAMTTRAPRDAAVL
LAIMLRDEPTVLLTERTAHLSNHSGQVAFPGGRVDPGDADAAAAALREAREEVGLDSGRAEVLGTLPVYATGTAFLVTPV
VALVQPEGSFQPNPYEVADIFEVPLAFLLDPSNHRRHALDIGGALREWFSMPYTDPATGKDHFIWGATAGMLRNFYRFLL
A

Sequences:

>Translated_241_residues
MSSSPSTAAAATAGPLTALPGFDPRTVPVLGTDAHLPAVPAAAWAPEALRRRFAAPPSWTPDVLRERAMTTRAPRDAAVL
LAIMLRDEPTVLLTERTAHLSNHSGQVAFPGGRVDPGDADAAAAALREAREEVGLDSGRAEVLGTLPVYATGTAFLVTPV
VALVQPEGSFQPNPYEVADIFEVPLAFLLDPSNHRRHALDIGGALREWFSMPYTDPATGKDHFIWGATAGMLRNFYRFLL
A
>Mature_240_residues
SSSPSTAAAATAGPLTALPGFDPRTVPVLGTDAHLPAVPAAAWAPEALRRRFAAPPSWTPDVLRERAMTTRAPRDAAVLL
AIMLRDEPTVLLTERTAHLSNHSGQVAFPGGRVDPGDADAAAAALREAREEVGLDSGRAEVLGTLPVYATGTAFLVTPVV
ALVQPEGSFQPNPYEVADIFEVPLAFLLDPSNHRRHALDIGGALREWFSMPYTDPATGKDHFIWGATAGMLRNFYRFLLA

Specific function: Probably mediates the hydrolysis of some nucleoside diphosphate derivatives [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI157785656, Length=155, Percent_Identity=40.6451612903226, Blast_Score=104, Evalue=7e-23,
Organism=Homo sapiens, GI32469515, Length=110, Percent_Identity=44.5454545454545, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1788115, Length=178, Percent_Identity=43.8202247191011, Blast_Score=102, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17536993, Length=161, Percent_Identity=31.6770186335404, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17510677, Length=136, Percent_Identity=36.0294117647059, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI18859683, Length=205, Percent_Identity=33.6585365853659, Blast_Score=83, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR000059 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: NA

Molecular weight: Translated: 25683; Mature: 25552

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSSPSTAAAATAGPLTALPGFDPRTVPVLGTDAHLPAVPAAAWAPEALRRRFAAPPSWT
CCCCCCCCHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCCCHHCCHHHHHHHHCCCCCCC
PDVLRERAMTTRAPRDAAVLLAIMLRDEPTVLLTERTAHLSNHSGQVAFPGGRVDPGDAD
HHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEECHHHHCCCCCEEECCCCCCCCCCHH
AAAAALREAREEVGLDSGRAEVLGTLPVYATGTAFLVTPVVALVQPEGSFQPNPYEVADI
HHHHHHHHHHHHHCCCCCCHHEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHH
FEVPLAFLLDPSNHRRHALDIGGALREWFSMPYTDPATGKDHFIWGATAGMLRNFYRFLL
HHHHHHEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECHHHHHHHHHHHHHC
A
C
>Mature Secondary Structure 
SSSPSTAAAATAGPLTALPGFDPRTVPVLGTDAHLPAVPAAAWAPEALRRRFAAPPSWT
CCCCCCCHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCCCHHCCHHHHHHHHCCCCCCC
PDVLRERAMTTRAPRDAAVLLAIMLRDEPTVLLTERTAHLSNHSGQVAFPGGRVDPGDAD
HHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEECHHHHCCCCCEEECCCCCCCCCCHH
AAAAALREAREEVGLDSGRAEVLGTLPVYATGTAFLVTPVVALVQPEGSFQPNPYEVADI
HHHHHHHHHHHHHCCCCCCHHEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHH
FEVPLAFLLDPSNHRRHALDIGGALREWFSMPYTDPATGKDHFIWGATAGMLRNFYRFLL
HHHHHHEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECHHHHHHHHHHHHHC
A
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]