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The map label for this gene is aidB [H]

Identifier: 120610521

GI number: 120610521

Start: 1995008

End: 1996723

Strand: Reverse

Name: aidB [H]

Synonym: Aave_1841

Alternate gene names: 120610521

Gene position: 1996723-1995008 (Counterclockwise)

Preceding gene: 120610523

Following gene: 120610520

Centisome position: 37.3

GC content: 70.75

Gene sequence:

>1716_bases
ATGCCGCAGCCTTTCCGGGCGGCCGATTCCCATCCGGTTCCGGATGGCCACGGCCGCAATCTGTTCGACACCGACACCGA
ACTGCAGTCCCTGCTGGCGCTCTATCTGCCGGACGCGCTCTATACCCACATGCGGCCGCACTTCGAGCGGCTGGGCGGTC
TCGCGGGGGGCCTGCTGGATGACCTGGCCGGCACCGCCGACCGGAATCCCCCGGTGCTCGAGCACCGGACGCGCACCGGC
CTCGACGTCCAGCGCATCGTCAAGCATCCGGCCTACGTGGAGATGGAACGTTTGGCGCTCAGCGAGTTCGGCCTCGGAGC
CATGTCCCACCGCGAGGAAACGCTGGGCTGGCAGGGCCCCATGCCGGCGCTGGTCAAGTACGTCCTGACCTACCTCTTCG
TGCAGGCCGAGTTCGGCCTGTGCTGCCCGGTCTCCATGACCGACTCGCTGACGCGCACGCTGCGCAGGTTCGGCAGCCCG
GAACTGCTGGCCCGCTATCTGCCGGCCCTCACGTCGCTCGATTTCGACGAACTGGCGCAGGGCGCCATGTTCATGACCGA
ACAGGGTGCCGGCTCCGACATCGCCGCCACCGCCACGCGGGCCACGCCCGCCGCGGACGGCAGCTGGCGCCTGACCGGAG
ACAAGTGGTTCTGCTCGAATCCCGACGCCGGGTTCGCGATGGTGCTGGCCCGCATCGACGGGGCACCGGAGGGCCTGAAG
GGGGTATCGCTCTTCCTGCTGCCGCGCCGCCTGGAGGACGGGAGCCTCAACCATTACCGCATCGTCCGGTTGAAAGACAA
GCTGGGCACGCGCTCCATGGCAAGCGGCGAGATCCGGCTCGCGGGCGCGGTGGCCCACCTCGTGGGCGAGGAAGGCCGGG
GCTTCGTGCAGATGGCCGACATGGTGAACAACTCGCGCCTGTCCAACGGCGTGCGCGCCGCGGGGCTGATGCGGCGGGCG
GTCTCCGAGGCCGAATTCGTCGCTTCCGAACGCCGTGCCTTCGGCCGTGCACTGCAGGACATGCCGCTCATGCGCCGCCA
GCTCGACAAGCTGCGCGTGCCGGCGGAGCAGGCCCGGACCATGGTGTTCCAGACCGCCCGTGCGCTCGCACGCTCGGACG
CGGGCGAGAAGGATGCCTATGCCCTGCTGCGCATCCTCACGCCGCTCATCAAGTTCCGAGCGTGCCGCGACGCGCGCAAG
GTGACCGGAGATGCGATGGAAGTGCGCGGCGGCTGCGGCTACATCGAGGAGTTCAGCGACGCGCGCCTGGTGCGCGACGC
GCACCTGGGCTCGATCTGGGAAGGCACGAGCAACATCGTCGCGCTGGACGTTCTGCGCGCCATCCGCCGGGAAGGCTCGC
TGCCCGTGCTGTCCGCGCACAACGCCGCGCTGCTGGAGGATGCCGCATTGCCCCCGGCCTTCGCCGCTGCCCTGGCCCAC
AGCTTCGAGCGCGCCTGCGCACTGGCCGAAACAGCGCTGCAGGACGACGGCGGCGAGGTGCTGGCCCGCCAGGCAGCGTC
CGCGCTCTACCACTGCACCAGCGCCATCGCCATGGCCTGGGAGGCGGCCAAGACCGGCTCGGCAGCGCGCATGCACTGGG
CCCGGATGGCGCTGTGGCACCGCGTGCTGCCGCGCGATCCCCTGCGGCCCGACTTGCCGCCTGCCGAATGGCAGGACCGC
CGCGGCGCGGCACGGGAGGCCGCCGCAACGGCCTGA

Upstream 100 bases:

>100_bases
CGGTATGGCGATAGGAGCTTCGAATGGCGCAAGACCTAATCGATATTAGACACGAATGGCCACGCGGCGAAGAATGGGAA
ATCGACAAGGAGACACCACG

Downstream 100 bases:

>100_bases
GCCATCCGCCCCCACAACCACAACCACAACGGAGACAAAGCAAGATGAAGAAACGCACCCTGATGTCCGCAGCCTGCGCC
CTGCTGGCGGCCTCTTTCCT

Product: acyl-CoA dehydrogenase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 571; Mature: 570

Protein sequence:

>571_residues
MPQPFRAADSHPVPDGHGRNLFDTDTELQSLLALYLPDALYTHMRPHFERLGGLAGGLLDDLAGTADRNPPVLEHRTRTG
LDVQRIVKHPAYVEMERLALSEFGLGAMSHREETLGWQGPMPALVKYVLTYLFVQAEFGLCCPVSMTDSLTRTLRRFGSP
ELLARYLPALTSLDFDELAQGAMFMTEQGAGSDIAATATRATPAADGSWRLTGDKWFCSNPDAGFAMVLARIDGAPEGLK
GVSLFLLPRRLEDGSLNHYRIVRLKDKLGTRSMASGEIRLAGAVAHLVGEEGRGFVQMADMVNNSRLSNGVRAAGLMRRA
VSEAEFVASERRAFGRALQDMPLMRRQLDKLRVPAEQARTMVFQTARALARSDAGEKDAYALLRILTPLIKFRACRDARK
VTGDAMEVRGGCGYIEEFSDARLVRDAHLGSIWEGTSNIVALDVLRAIRREGSLPVLSAHNAALLEDAALPPAFAAALAH
SFERACALAETALQDDGGEVLARQAASALYHCTSAIAMAWEAAKTGSAARMHWARMALWHRVLPRDPLRPDLPPAEWQDR
RGAAREAAATA

Sequences:

>Translated_571_residues
MPQPFRAADSHPVPDGHGRNLFDTDTELQSLLALYLPDALYTHMRPHFERLGGLAGGLLDDLAGTADRNPPVLEHRTRTG
LDVQRIVKHPAYVEMERLALSEFGLGAMSHREETLGWQGPMPALVKYVLTYLFVQAEFGLCCPVSMTDSLTRTLRRFGSP
ELLARYLPALTSLDFDELAQGAMFMTEQGAGSDIAATATRATPAADGSWRLTGDKWFCSNPDAGFAMVLARIDGAPEGLK
GVSLFLLPRRLEDGSLNHYRIVRLKDKLGTRSMASGEIRLAGAVAHLVGEEGRGFVQMADMVNNSRLSNGVRAAGLMRRA
VSEAEFVASERRAFGRALQDMPLMRRQLDKLRVPAEQARTMVFQTARALARSDAGEKDAYALLRILTPLIKFRACRDARK
VTGDAMEVRGGCGYIEEFSDARLVRDAHLGSIWEGTSNIVALDVLRAIRREGSLPVLSAHNAALLEDAALPPAFAAALAH
SFERACALAETALQDDGGEVLARQAASALYHCTSAIAMAWEAAKTGSAARMHWARMALWHRVLPRDPLRPDLPPAEWQDR
RGAAREAAATA
>Mature_570_residues
PQPFRAADSHPVPDGHGRNLFDTDTELQSLLALYLPDALYTHMRPHFERLGGLAGGLLDDLAGTADRNPPVLEHRTRTGL
DVQRIVKHPAYVEMERLALSEFGLGAMSHREETLGWQGPMPALVKYVLTYLFVQAEFGLCCPVSMTDSLTRTLRRFGSPE
LLARYLPALTSLDFDELAQGAMFMTEQGAGSDIAATATRATPAADGSWRLTGDKWFCSNPDAGFAMVLARIDGAPEGLKG
VSLFLLPRRLEDGSLNHYRIVRLKDKLGTRSMASGEIRLAGAVAHLVGEEGRGFVQMADMVNNSRLSNGVRAAGLMRRAV
SEAEFVASERRAFGRALQDMPLMRRQLDKLRVPAEQARTMVFQTARALARSDAGEKDAYALLRILTPLIKFRACRDARKV
TGDAMEVRGGCGYIEEFSDARLVRDAHLGSIWEGTSNIVALDVLRAIRREGSLPVLSAHNAALLEDAALPPAFAAALAHS
FERACALAETALQDDGGEVLARQAASALYHCTSAIAMAWEAAKTGSAARMHWARMALWHRVLPRDPLRPDLPPAEWQDRR
GAAREAAATA

Specific function: May help to prevent alkylation damage by protecting DNA and destroying alkylating agents [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501859, Length=323, Percent_Identity=28.4829721362229, Blast_Score=109, Evalue=7e-24,
Organism=Homo sapiens, GI4557233, Length=322, Percent_Identity=27.9503105590062, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI21361497, Length=295, Percent_Identity=26.1016949152542, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI226958412, Length=308, Percent_Identity=25.3246753246753, Blast_Score=91, Evalue=4e-18,
Organism=Homo sapiens, GI226958414, Length=308, Percent_Identity=25.3246753246753, Blast_Score=91, Evalue=4e-18,
Organism=Homo sapiens, GI4557235, Length=297, Percent_Identity=27.2727272727273, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI76496475, Length=297, Percent_Identity=27.2727272727273, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI4501857, Length=303, Percent_Identity=27.3927392739274, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI187960098, Length=297, Percent_Identity=28.6195286195286, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI4557231, Length=297, Percent_Identity=28.6195286195286, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI7656849, Length=312, Percent_Identity=24.3589743589744, Blast_Score=76, Evalue=9e-14,
Organism=Escherichia coli, GI87082384, Length=415, Percent_Identity=34.4578313253012, Blast_Score=197, Evalue=2e-51,
Organism=Escherichia coli, GI87081958, Length=303, Percent_Identity=28.3828382838284, Blast_Score=92, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI86563381, Length=443, Percent_Identity=33.1828442437923, Blast_Score=219, Evalue=3e-57,
Organism=Caenorhabditis elegans, GI86563383, Length=443, Percent_Identity=33.1828442437923, Blast_Score=219, Evalue=3e-57,
Organism=Caenorhabditis elegans, GI17508101, Length=313, Percent_Identity=28.1150159744409, Blast_Score=115, Evalue=8e-26,
Organism=Caenorhabditis elegans, GI17538396, Length=302, Percent_Identity=28.8079470198675, Blast_Score=105, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI17506239, Length=313, Percent_Identity=27.4760383386581, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17551932, Length=300, Percent_Identity=30, Blast_Score=89, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17505929, Length=311, Percent_Identity=29.5819935691318, Blast_Score=89, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17570075, Length=267, Percent_Identity=26.9662921348315, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17533517, Length=309, Percent_Identity=26.2135922330097, Blast_Score=79, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17534899, Length=297, Percent_Identity=25.2525252525253, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17569725, Length=295, Percent_Identity=25.7627118644068, Blast_Score=75, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI71985184, Length=294, Percent_Identity=25.5102040816327, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71990804, Length=214, Percent_Identity=26.1682242990654, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71982178, Length=193, Percent_Identity=32.1243523316062, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24666513, Length=315, Percent_Identity=26.6666666666667, Blast_Score=105, Evalue=7e-23,
Organism=Drosophila melanogaster, GI281363737, Length=307, Percent_Identity=26.3843648208469, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI21355753, Length=303, Percent_Identity=27.0627062706271, Blast_Score=97, Evalue=4e-20,
Organism=Drosophila melanogaster, GI21356377, Length=370, Percent_Identity=25.9459459459459, Blast_Score=86, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24660351, Length=292, Percent_Identity=27.7397260273973, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24646207, Length=271, Percent_Identity=24.7232472324723, Blast_Score=76, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M [H]

EC number: NA

Molecular weight: Translated: 62327; Mature: 62196

Theoretical pI: Translated: 7.42; Mature: 7.42

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQPFRAADSHPVPDGHGRNLFDTDTELQSLLALYLPDALYTHMRPHFERLGGLAGGLLD
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLAGTADRNPPVLEHRTRTGLDVQRIVKHPAYVEMERLALSEFGLGAMSHREETLGWQGP
HHCCCCCCCCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCC
MPALVKYVLTYLFVQAEFGLCCPVSMTDSLTRTLRRFGSPELLARYLPALTSLDFDELAQ
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHC
GAMFMTEQGAGSDIAATATRATPAADGSWRLTGDKWFCSNPDAGFAMVLARIDGAPEGLK
CCEEEECCCCCCCHHHHCCCCCCCCCCCEEECCCEEEECCCCCCHHHHHHHHCCCCCCCC
GVSLFLLPRRLEDGSLNHYRIVRLKDKLGTRSMASGEIRLAGAVAHLVGEEGRGFVQMAD
CCEEEEECCCCCCCCCCCEEEEEEHHHCCCCCCCCCCEEHHHHHHHHHCCCCCCHHHHHH
MVNNSRLSNGVRAAGLMRRAVSEAEFVASERRAFGRALQDMPLMRRQLDKLRVPAEQART
HHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
MVFQTARALARSDAGEKDAYALLRILTPLIKFRACRDARKVTGDAMEVRGGCGYIEEFSD
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHH
ARLVRDAHLGSIWEGTSNIVALDVLRAIRREGSLPVLSAHNAALLEDAALPPAFAAALAH
HHHHHHHHCCCHHCCCCCHHHHHHHHHHHHCCCCCEEECCCHHHHHHCCCCHHHHHHHHH
SFERACALAETALQDDGGEVLARQAASALYHCTSAIAMAWEAAKTGSAARMHWARMALWH
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
RVLPRDPLRPDLPPAEWQDRRGAAREAAATA
HHCCCCCCCCCCCCCCHHHHCCHHHHHHCCC
>Mature Secondary Structure 
PQPFRAADSHPVPDGHGRNLFDTDTELQSLLALYLPDALYTHMRPHFERLGGLAGGLLD
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLAGTADRNPPVLEHRTRTGLDVQRIVKHPAYVEMERLALSEFGLGAMSHREETLGWQGP
HHCCCCCCCCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCC
MPALVKYVLTYLFVQAEFGLCCPVSMTDSLTRTLRRFGSPELLARYLPALTSLDFDELAQ
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHC
GAMFMTEQGAGSDIAATATRATPAADGSWRLTGDKWFCSNPDAGFAMVLARIDGAPEGLK
CCEEEECCCCCCCHHHHCCCCCCCCCCCEEECCCEEEECCCCCCHHHHHHHHCCCCCCCC
GVSLFLLPRRLEDGSLNHYRIVRLKDKLGTRSMASGEIRLAGAVAHLVGEEGRGFVQMAD
CCEEEEECCCCCCCCCCCEEEEEEHHHCCCCCCCCCCEEHHHHHHHHHCCCCCCHHHHHH
MVNNSRLSNGVRAAGLMRRAVSEAEFVASERRAFGRALQDMPLMRRQLDKLRVPAEQART
HHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
MVFQTARALARSDAGEKDAYALLRILTPLIKFRACRDARKVTGDAMEVRGGCGYIEEFSD
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHH
ARLVRDAHLGSIWEGTSNIVALDVLRAIRREGSLPVLSAHNAALLEDAALPPAFAAALAH
HHHHHHHHCCCHHCCCCCHHHHHHHHHHHHCCCCCEEECCCHHHHHHCCCCHHHHHHHHH
SFERACALAETALQDDGGEVLARQAASALYHCTSAIAMAWEAAKTGSAARMHWARMALWH
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
RVLPRDPLRPDLPPAEWQDRRGAAREAAATA
HHCCCCCCCCCCCCCCHHHHCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7961409; 7610040; 9278503 [H]