Click here to switch to the map view.

The map label for this gene is yfcG [H]

Identifier: 120609492

GI number: 120609492

Start: 860126

End: 860839

Strand: Reverse

Name: yfcG [H]

Synonym: Aave_0798

Alternate gene names: 120609492

Gene position: 860839-860126 (Counterclockwise)

Preceding gene: 120609497

Following gene: 120609488

Centisome position: 16.08

GC content: 69.33

Gene sequence:

>714_bases
ATGACCGACGACGTGCTCGCCGCCTTCCCCATCACCCGCAAGTGGCCCGCCCGCCACCCCGACCGGCTGCAGCTCTATTC
GCTGCCCACGCCCAACGGCGTGAAGGCCTCCATCCTGCTGGAGGAGACCGGCCTGCCCTATGAAGCGCACCTCGTGCGCT
TCGACCAGGACGACCAAACCTCGCCGGAATTCCTCTCGCTCAATCCCAACAACAAGATCCCGGCCATCCTGGACCCGGAC
GGCCCCGGCGGCCAGCCCCTGGCGCTGTTCGAGTCCGGCGCCATCCTGGTCTATCTGGCCGACAAGACCGGCCGCTTCCT
GGCCCCCGCGGGCGCGCAGCGCTATGCCGCGCTGCAGTGGCTGATGTGGCAGATGGGCGGCGTCGGCCCCATGTTCGGCC
AGCTCGGCTTCTTCCACAAGTTCGCCGGCAAGGACTACGAGGACAAGCGCCCGCGCGACCGCTACGTGGCCGAGAGCCGT
CGCCTGCTGGGCGTGCTGGACCGCCACCTGGCCGACGGCCGCGCCTGGATGGTGGGCGAGGACTACACCATCGCCGACAT
CGCGGTGTTCCCGTGGGTACGCAACCTCGTGGGCTTCTACGAGGCGGGCGAGCTGGTGGAGTTCGACCGGTTCACCCATG
TGCGCCGGGTGCTGGATGCCTTCGTGGCCCGGCCCGCCGTGGCGCGCGGACTGGAGATTCCCGTGAGAAGCTAG

Upstream 100 bases:

>100_bases
GGCAGGCGCGGCATGGCCCCTCGCCGGCAGGGGCCGGCCGGGCGCGCGATGATGGCGCCCTCCATCCCCTGCGCCCATCC
CTTAGCCCCGAGGAGTTCAG

Downstream 100 bases:

>100_bases
GCCATCGCGAGCCCGGCGAGCCCCGCGGCGAGGATGACGGGGATGACGCCCACCCGCCAGCGCATCAGCGCCACCGCCGA
AGCCGCCCCGATGAGCAGCA

Product: glutathione S-transferase domain-containing protein

Products: NA

Alternate protein names: GST-like protein yfcG [H]

Number of amino acids: Translated: 237; Mature: 236

Protein sequence:

>237_residues
MTDDVLAAFPITRKWPARHPDRLQLYSLPTPNGVKASILLEETGLPYEAHLVRFDQDDQTSPEFLSLNPNNKIPAILDPD
GPGGQPLALFESGAILVYLADKTGRFLAPAGAQRYAALQWLMWQMGGVGPMFGQLGFFHKFAGKDYEDKRPRDRYVAESR
RLLGVLDRHLADGRAWMVGEDYTIADIAVFPWVRNLVGFYEAGELVEFDRFTHVRRVLDAFVARPAVARGLEIPVRS

Sequences:

>Translated_237_residues
MTDDVLAAFPITRKWPARHPDRLQLYSLPTPNGVKASILLEETGLPYEAHLVRFDQDDQTSPEFLSLNPNNKIPAILDPD
GPGGQPLALFESGAILVYLADKTGRFLAPAGAQRYAALQWLMWQMGGVGPMFGQLGFFHKFAGKDYEDKRPRDRYVAESR
RLLGVLDRHLADGRAWMVGEDYTIADIAVFPWVRNLVGFYEAGELVEFDRFTHVRRVLDAFVARPAVARGLEIPVRS
>Mature_236_residues
TDDVLAAFPITRKWPARHPDRLQLYSLPTPNGVKASILLEETGLPYEAHLVRFDQDDQTSPEFLSLNPNNKIPAILDPDG
PGGQPLALFESGAILVYLADKTGRFLAPAGAQRYAALQWLMWQMGGVGPMFGQLGFFHKFAGKDYEDKRPRDRYVAESRR
LLGVLDRHLADGRAWMVGEDYTIADIAVFPWVRNLVGFYEAGELVEFDRFTHVRRVLDAFVARPAVARGLEIPVRS

Specific function: Has disulfide bond reductase activity (in vitro). Has low hydroperoxidase activity with cumene hydroperoxide. Has very low glutathione-S-transferase activity (in vitro) [H]

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1788640, Length=210, Percent_Identity=42.8571428571429, Blast_Score=157, Evalue=7e-40,
Organism=Escherichia coli, GI87082195, Length=222, Percent_Identity=42.3423423423423, Blast_Score=156, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6324100, Length=241, Percent_Identity=31.5352697095436, Blast_Score=96, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: NA

Molecular weight: Translated: 26625; Mature: 26494

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDDVLAAFPITRKWPARHPDRLQLYSLPTPNGVKASILLEETGLPYEAHLVRFDQDDQT
CCCCEEEECCCCCCCCCCCCCCEEEEECCCCCCCEEEEEEECCCCCEEEEEEEECCCCCC
SPEFLSLNPNNKIPAILDPDGPGGQPLALFESGAILVYLADKTGRFLAPAGAQRYAALQW
CCCEEEECCCCCCCEEECCCCCCCCEEEEEECCEEEEEEECCCCCEECCCCHHHHHHHHH
LMWQMGGVGPMFGQLGFFHKFAGKDYEDKRPRDRYVAESRRLLGVLDRHLADGRAWMVGE
HHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEC
DYTIADIAVFPWVRNLVGFYEAGELVEFDRFTHVRRVLDAFVARPAVARGLEIPVRS
CCEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCC
>Mature Secondary Structure 
TDDVLAAFPITRKWPARHPDRLQLYSLPTPNGVKASILLEETGLPYEAHLVRFDQDDQT
CCCEEEECCCCCCCCCCCCCCEEEEECCCCCCCEEEEEEECCCCCEEEEEEEECCCCCC
SPEFLSLNPNNKIPAILDPDGPGGQPLALFESGAILVYLADKTGRFLAPAGAQRYAALQW
CCCEEEECCCCCCCEEECCCCCCCCEEEEEECCEEEEEEECCCCCEECCCCHHHHHHHHH
LMWQMGGVGPMFGQLGFFHKFAGKDYEDKRPRDRYVAESRRLLGVLDRHLADGRAWMVGE
HHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEC
DYTIADIAVFPWVRNLVGFYEAGELVEFDRFTHVRRVLDAFVARPAVARGLEIPVRS
CCEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]