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The map label for this gene is rsuA [C]

Identifier: 120609486

GI number: 120609486

Start: 853172

End: 853975

Strand: Reverse

Name: rsuA [C]

Synonym: Aave_0792

Alternate gene names: 120609486

Gene position: 853975-853172 (Counterclockwise)

Preceding gene: 120609487

Following gene: 120609485

Centisome position: 15.95

GC content: 74.13

Gene sequence:

>804_bases
ATGCATGATCTTTCCCCCGATGGCACCGGCGCCGGAGAAGCCGGCCACATCCGCCTGTCGAAGCGCGTCGCCGAGATGCG
CGGCTGCTCCCGCCGCGAGGCCGAGTGGCTCATCGAAGGCGGCTGGGTGCAGGTGGACGGGCGGATGACCGAGGCGCCGG
GCGCCCGTGTCCGCCCGGACCAGGACGTCGTGGTCGCGCAGAACGCCAAGGCCGAGGAGGCGCCGCCCGTCACCCTCCTG
CTGCACAAGCCCGCCGGCTGGGAGGCCGGCATCGGCCACGGCCCCGCCGGCGATCCGCGCCAGGCGCGCAGCGGCGGGGC
TCCCGACGCCGGCACGCTGCTGGAGCCCGGCCGCCGGTACGTGGGCGACAGCCCGCCCGTGCGGGTGCTGCAGCGGCATT
TCAGGCAGCAGGAGTGCTTCACGCCGCTGGCCGACGCGGCCAGCGGGCTCGTGGTCTATACGCAGGACCGGCGCATGGCG
CGCCGCCTGGCCGAAGACATCGAACTGCTCGAACAGGAATGCATCGCCACGGTGGACGGCCGCATCGCCGAGGGCGGCCT
CGAACGGCTCTGCCGGGGGCTGGAGTTCAACGGCCGGCCCCTGCCGCCGGCCAAGGTGAGCTGGCAGAGCGAGACGCGGC
TGCGCTTCGCGCTCAAGGGCATCCGCCCGGGGCAGATCCCCGCGATGTGCGAGGCCGTCGGCCTGCAGGTGACGGCGCTC
AAGCGGCTGCGCATCGGCCGCGTCTCGCTCGCCAGGGTGCCCGAAGGGCAGTGGCGCTACCTGCTGCCCTGGGAGCGCTT
CTGA

Upstream 100 bases:

>100_bases
GTGCGCCACGCCTATGCCGACGTGCCCGAGCGGCTGTGGCCCGTGGCGCAGCGCTCCCTGCTGGCCCACGTGGAGCGCCT
GCGCGCGCTGGAGGCCGGCC

Downstream 100 bases:

>100_bases
TTCGCCCGCCGCCGCGATAAACTGCCGGGCTCTTCGAGGGAGGCACATCCATGGATCAACGCGTCGAGCCCCACGTGGCA
CGCATGGCGTCATCGTTCAC

Product: RNA-binding S4 domain-containing protein

Products: pseudouridine 5'-phosphate; H2O [C]

Alternate protein names: Pseudouridylate Synthase; Pseudouridine Synthase Rsu; Ribosomal Large Subunit Pseudouridine Synthase F; RNA Pseudouridylate Synthase; S4 Domain-Containing Protein; Pseudouridine Synthase Family Protein; Ribosomal Large Subunit Pseudouridine Synthase B; Ribosomal Small Subunit Pseudouridylate Synthase; RNA Pseudouridylate Synthase Family Protein; Pseudouridylate Synthase Protein; RNA Pseudouridine Synthase Family Protein; Ribosomal Large Subunit Pseudouridine Synthase; Propable; 16S Pseudouridylate Synthase; Arginine/Proline Rich Protein

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MHDLSPDGTGAGEAGHIRLSKRVAEMRGCSRREAEWLIEGGWVQVDGRMTEAPGARVRPDQDVVVAQNAKAEEAPPVTLL
LHKPAGWEAGIGHGPAGDPRQARSGGAPDAGTLLEPGRRYVGDSPPVRVLQRHFRQQECFTPLADAASGLVVYTQDRRMA
RRLAEDIELLEQECIATVDGRIAEGGLERLCRGLEFNGRPLPPAKVSWQSETRLRFALKGIRPGQIPAMCEAVGLQVTAL
KRLRIGRVSLARVPEGQWRYLLPWERF

Sequences:

>Translated_267_residues
MHDLSPDGTGAGEAGHIRLSKRVAEMRGCSRREAEWLIEGGWVQVDGRMTEAPGARVRPDQDVVVAQNAKAEEAPPVTLL
LHKPAGWEAGIGHGPAGDPRQARSGGAPDAGTLLEPGRRYVGDSPPVRVLQRHFRQQECFTPLADAASGLVVYTQDRRMA
RRLAEDIELLEQECIATVDGRIAEGGLERLCRGLEFNGRPLPPAKVSWQSETRLRFALKGIRPGQIPAMCEAVGLQVTAL
KRLRIGRVSLARVPEGQWRYLLPWERF
>Mature_267_residues
MHDLSPDGTGAGEAGHIRLSKRVAEMRGCSRREAEWLIEGGWVQVDGRMTEAPGARVRPDQDVVVAQNAKAEEAPPVTLL
LHKPAGWEAGIGHGPAGDPRQARSGGAPDAGTLLEPGRRYVGDSPPVRVLQRHFRQQECFTPLADAASGLVVYTQDRRMA
RRLAEDIELLEQECIATVDGRIAEGGLERLCRGLEFNGRPLPPAKVSWQSETRLRFALKGIRPGQIPAMCEAVGLQVTAL
KRLRIGRVSLARVPEGQWRYLLPWERF

Specific function: Responsible For Synthesis Of Pseudouridine From Uracil-516 In 16s Ribosomal RNA. [C]

COG id: COG1187

COG function: function code J; 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 4.2.1.70 [C]

Molecular weight: Translated: 29354; Mature: 29354

Theoretical pI: Translated: 8.76; Mature: 8.76

Prosite motif: PS50889 S4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHDLSPDGTGAGEAGHIRLSKRVAEMRGCSRREAEWLIEGGWVQVDGRMTEAPGARVRPD
CCCCCCCCCCCCCCCEEHHHHHHHHHHCCCCCCCCEEEECCEEEECCEEECCCCCCCCCC
QDVVVAQNAKAEEAPPVTLLLHKPAGWEAGIGHGPAGDPRQARSGGAPDAGTLLEPGRRY
CCEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCHHH
VGDSPPVRVLQRHFRQQECFTPLADAASGLVVYTQDRRMARRLAEDIELLEQECIATVDG
CCCCCCHHHHHHHHHHHHHCCCHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCC
RIAEGGLERLCRGLEFNGRPLPPAKVSWQSETRLRFALKGIRPGQIPAMCEAVGLQVTAL
CHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHEEHHCCCCCCCCCHHHHHHHCCHHHHH
KRLRIGRVSLARVPEGQWRYLLPWERF
HHHHHCCEEEEECCCCCEEEECCCCCC
>Mature Secondary Structure
MHDLSPDGTGAGEAGHIRLSKRVAEMRGCSRREAEWLIEGGWVQVDGRMTEAPGARVRPD
CCCCCCCCCCCCCCCEEHHHHHHHHHHCCCCCCCCEEEECCEEEECCEEECCCCCCCCCC
QDVVVAQNAKAEEAPPVTLLLHKPAGWEAGIGHGPAGDPRQARSGGAPDAGTLLEPGRRY
CCEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCHHH
VGDSPPVRVLQRHFRQQECFTPLADAASGLVVYTQDRRMARRLAEDIELLEQECIATVDG
CCCCCCHHHHHHHHHHHHHCCCHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCC
RIAEGGLERLCRGLEFNGRPLPPAKVSWQSETRLRFALKGIRPGQIPAMCEAVGLQVTAL
CHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHEEHHCCCCCCCCCHHHHHHHCCHHHHH
KRLRIGRVSLARVPEGQWRYLLPWERF
HHHHHCCEEEEECCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: uracil; D-ribose phosphate [C]

Specific reaction: uracil + D-ribose phosphate = pseudouridine 5'-phosphate + H2O [C]

General reaction: addition of H2O; elimination of H2O; C-O bond cleavage [C]

Inhibitor: 1-(Tetrahydro-2-furanyl)-5-fluorouracil; 5-fluorouracil [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA