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The map label for this gene is hipO [H]

Identifier: 120609464

GI number: 120609464

Start: 827101

End: 828312

Strand: Direct

Name: hipO [H]

Synonym: Aave_0770

Alternate gene names: 120609464

Gene position: 827101-828312 (Clockwise)

Preceding gene: 120609462

Following gene: 120609465

Centisome position: 15.45

GC content: 69.47

Gene sequence:

>1212_bases
ATGAAACTCATCGACTCCATCGTCACCGAGGCGGCAGGCATCGCCGCCGTGCGCCGCGACATCCACGCGCATCCCGAACT
GTGCTTCGAGGAAGTGCGCACGGCCGACATCGTGGCCGCCAAGCTCGCCGAGTGGGGCATTCCGGTCCACCGGGGGCTGG
GCAAGACGGGCGTCGTGGGCATCGTGCACGGCCGCGACGGCGGCGCCTCGGGCCGCGCGGTGGGCCTGCGCGCCGACATG
GACGCGCTGCCCATCACCGAATTCAACACCTTCTCGCACGCCAGCACCCACCCCGGCAAGATGCACGCCTGCGGCCACGA
CGGCCACACGGCCATGCTGCTCGGCGCGGCCCAGCATTTCGCGAAGCACCGCGACTTCGACGGCACCGTGTACCTGATCT
TCCAGCCGGCGGAAGAGGGCGGCGGCGGCGCGCGCGTGATGATCGAGGACGGCCTGTTCACCCAATTCCCGGTGGAGGCC
GTGTTCGGCATGCACAACTGGCCCGGCATGCGCGCCGGCCAGTTCGCGGTCAGCCCCGGCCCGGTCATGGCCTCGTCCAA
CGAATTCAGGATCGTCATCCGCGGCAAGGGCAGCCATGCCGCCATGCCGCACATGGGCATCGACCCGGTGCCCGTGGCCT
GCCAGATGGTGCAGGCGTTCCAGAACATCATCAGCCGCAACAAGAAGCCGGTCGATGCCGGCGTGATCTCGGTCACCATG
ATCCACACCGGCGAGGCCACCAACGTGGTGCCCGACAGCTGCGAACTGCAGGGCACGGTGCGCACCTTCACGCTGGAAGT
GCTCGACATGATCGAGCGCCGCATGCGGCAGGTGGCCGAGCACACCTGCGCCGCCCACGACGCGGTGTGCGAGTTCGAGT
TCCACCGCAACTACCCACCGACCGTGAATTCGCCGGCCGAGGCCGCGTTCGCGCGCCGCGTGATGGAGGGCATCGTGGGC
GCGGAGCACGTCTCCCCGCAGGAGCCCACCATGGGCGCGGAGGATTTCGCGTTCATGCTGCAGGCCAGGCCCGGCGCCTA
CTGCTTCATCGGCAACGGCGAAGGCACGCACCGCGAGATGGGCCATGGCGGCGGCCCCTGCACGCTGCACAACCCGAGCT
ACGACTTCAACGACGACCTGCTCCCGCTGGGCGCCACCTACTGGGTGGAACTGGCCCGGCAGTGGCTGTCGTCGCCGCGG
CCCGCCGCCTGA

Upstream 100 bases:

>100_bases
GCGAGAGGGCGTGTTCGGACAGCATCGTGGGGTGGAATAACCCTGTCTGGTGCGCGTGCGGAGGCAGGGCTAGACTCTCT
GGACCAAGGAAGCATCCATT

Downstream 100 bases:

>100_bases
CGCCGGGCGCGCCGCGGCCTGCATGCCGGGCCGTGGCGCACCTTCCGGCCGCTTCCTGTCCCTTCCCTTTCCGCTCCCCT
TCCCGCCGGCACTGCGGGCC

Product: amidohydrolase

Products: NA

Alternate protein names: Benzoylglycine amidohydrolase; Hippuricase [H]

Number of amino acids: Translated: 403; Mature: 403

Protein sequence:

>403_residues
MKLIDSIVTEAAGIAAVRRDIHAHPELCFEEVRTADIVAAKLAEWGIPVHRGLGKTGVVGIVHGRDGGASGRAVGLRADM
DALPITEFNTFSHASTHPGKMHACGHDGHTAMLLGAAQHFAKHRDFDGTVYLIFQPAEEGGGGARVMIEDGLFTQFPVEA
VFGMHNWPGMRAGQFAVSPGPVMASSNEFRIVIRGKGSHAAMPHMGIDPVPVACQMVQAFQNIISRNKKPVDAGVISVTM
IHTGEATNVVPDSCELQGTVRTFTLEVLDMIERRMRQVAEHTCAAHDAVCEFEFHRNYPPTVNSPAEAAFARRVMEGIVG
AEHVSPQEPTMGAEDFAFMLQARPGAYCFIGNGEGTHREMGHGGGPCTLHNPSYDFNDDLLPLGATYWVELARQWLSSPR
PAA

Sequences:

>Translated_403_residues
MKLIDSIVTEAAGIAAVRRDIHAHPELCFEEVRTADIVAAKLAEWGIPVHRGLGKTGVVGIVHGRDGGASGRAVGLRADM
DALPITEFNTFSHASTHPGKMHACGHDGHTAMLLGAAQHFAKHRDFDGTVYLIFQPAEEGGGGARVMIEDGLFTQFPVEA
VFGMHNWPGMRAGQFAVSPGPVMASSNEFRIVIRGKGSHAAMPHMGIDPVPVACQMVQAFQNIISRNKKPVDAGVISVTM
IHTGEATNVVPDSCELQGTVRTFTLEVLDMIERRMRQVAEHTCAAHDAVCEFEFHRNYPPTVNSPAEAAFARRVMEGIVG
AEHVSPQEPTMGAEDFAFMLQARPGAYCFIGNGEGTHREMGHGGGPCTLHNPSYDFNDDLLPLGATYWVELARQWLSSPR
PAA
>Mature_403_residues
MKLIDSIVTEAAGIAAVRRDIHAHPELCFEEVRTADIVAAKLAEWGIPVHRGLGKTGVVGIVHGRDGGASGRAVGLRADM
DALPITEFNTFSHASTHPGKMHACGHDGHTAMLLGAAQHFAKHRDFDGTVYLIFQPAEEGGGGARVMIEDGLFTQFPVEA
VFGMHNWPGMRAGQFAVSPGPVMASSNEFRIVIRGKGSHAAMPHMGIDPVPVACQMVQAFQNIISRNKKPVDAGVISVTM
IHTGEATNVVPDSCELQGTVRTFTLEVLDMIERRMRQVAEHTCAAHDAVCEFEFHRNYPPTVNSPAEAAFARRVMEGIVG
AEHVSPQEPTMGAEDFAFMLQARPGAYCFIGNGEGTHREMGHGGGPCTLHNPSYDFNDDLLPLGATYWVELARQWLSSPR
PAA

Specific function: Required But Not Essential For Aminobenzoyl-Glutamate Utilization. May Participate In Hydrolysis Of Aminobenzoyl- Glutamate To Aminobenzoate, Either Alone Or In Combination With Abgb. [C]

COG id: COG1473

COG function: function code R; Metal-dependent amidase/aminoacylase/carboxypeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20 family [H]

Homologues:

Organism=Escherichia coli, GI87081880, Length=431, Percent_Identity=27.3781902552204, Blast_Score=95, Evalue=7e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017439
- InterPro:   IPR010168
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.32 [H]

Molecular weight: Translated: 43444; Mature: 43444

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLIDSIVTEAAGIAAVRRDIHAHPELCFEEVRTADIVAAKLAEWGIPVHRGLGKTGVVG
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCEEE
IVHGRDGGASGRAVGLRADMDALPITEFNTFSHASTHPGKMHACGHDGHTAMLLGAAQHF
EEECCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCEEEEHHHHHHH
AKHRDFDGTVYLIFQPAEEGGGGARVMIEDGLFTQFPVEAVFGMHNWPGMRAGQFAVSPG
HHHCCCCCEEEEEEEECCCCCCEEEEEEECCCCCCCCHHHHHCCCCCCCCCCCCEEECCC
PVMASSNEFRIVIRGKGSHAAMPHMGIDPVPVACQMVQAFQNIISRNKKPVDAGVISVTM
CEEECCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEE
IHTGEATNVVPDSCELQGTVRTFTLEVLDMIERRMRQVAEHTCAAHDAVCEFEFHRNYPP
EECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCC
TVNSPAEAAFARRVMEGIVGAEHVSPQEPTMGAEDFAFMLQARPGAYCFIGNGEGTHREM
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHEEEEECCCCCEEEEECCCCCHHHC
GHGGGPCTLHNPSYDFNDDLLPLGATYWVELARQWLSSPRPAA
CCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKLIDSIVTEAAGIAAVRRDIHAHPELCFEEVRTADIVAAKLAEWGIPVHRGLGKTGVVG
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCEEE
IVHGRDGGASGRAVGLRADMDALPITEFNTFSHASTHPGKMHACGHDGHTAMLLGAAQHF
EEECCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCEEEEHHHHHHH
AKHRDFDGTVYLIFQPAEEGGGGARVMIEDGLFTQFPVEAVFGMHNWPGMRAGQFAVSPG
HHHCCCCCEEEEEEEECCCCCCEEEEEEECCCCCCCCHHHHHCCCCCCCCCCCCEEECCC
PVMASSNEFRIVIRGKGSHAAMPHMGIDPVPVACQMVQAFQNIISRNKKPVDAGVISVTM
CEEECCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEE
IHTGEATNVVPDSCELQGTVRTFTLEVLDMIERRMRQVAEHTCAAHDAVCEFEFHRNYPP
EECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCC
TVNSPAEAAFARRVMEGIVGAEHVSPQEPTMGAEDFAFMLQARPGAYCFIGNGEGTHREM
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHEEEEECCCCCEEEEECCCCCHHHC
GHGGGPCTLHNPSYDFNDDLLPLGATYWVELARQWLSSPRPAA
CCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7730270; 10688204 [H]