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The map label for this gene is argE [H]

Identifier: 120609463

GI number: 120609463

Start: 825865

End: 827025

Strand: Reverse

Name: argE [H]

Synonym: Aave_0769

Alternate gene names: 120609463

Gene position: 827025-825865 (Counterclockwise)

Preceding gene: 120609468

Following gene: 120609461

Centisome position: 15.45

GC content: 69.94

Gene sequence:

>1161_bases
ATGCTGTCCGAACACGCCCTCTCGCTCGCCCAGGCCCTGGTGCGCATGAATACCGTGAGCCACCGCTCCAACCTGGAGCT
CATCGATTTCATCCGCACGGAACTGGATCGCCTCGGCGTGAAGTGCCGGCTGACCTACGACGCAAGCAAGACCAAGGCCA
ATCTGTTCGCCACCCTGGGCGAGGGCAAGCCCGCGGGCATCATCCTCTCGGGCCACACCGACACCGTGCCCTGGGACGGC
CAGGACTGGAGCATGGACCCGCTCTCGGCCACGGTGCAAGGCGGCCGGCTCCACGGCCGGGGCAGCGCCGACATGAAGGC
CTTCATCGCCATCGCGCTGTCGCAGGCGCGCCAGTTCCTGGAAAGCGACGCGCCCTTCGCCATCCACTATGCCTTCAGCT
ACGACGAGGAAGTAGGCTGCTTCGGCGCGCGCGAACTCATCGCCGACATGCGCGAGGCCGGCGTGCGGCCGCTGGCCTGC
ATCGTGGGCGAACCCACCGACATGGTGCCGGCCATCGCGCACAAGGGGGTGTACCGCTACCGCTGCTGCGTGCGCGGCAA
GGAAGCGCACTCCTCGCTCACGCCGCATTCGGTGAACGCGATCGAGATGGCCGCGCGCGTGGTGGGTCGCGTGCGCGACA
TGGCCGAGGGCTTCGAGCGCGAGGAGCCGCGCTGGGACGGCTTCGACGTGCCGTTTTCCACCGCCAGCGTGGGCCAGTTC
CACGGCGGCATCGCCGACAACGTGGTGCCGCGCGACGCGGAGTTCCGCTACGAGTTCCGCGACCTGCCCACGGCCGACGC
GGCCCGCATGCAGGCCGAGGTGGTGGCCTATGCGCGCTGGCTGGAGCCCGCGATGCAGGCGGTGGCGCCGCAGGCGGGCA
TCACTTTCGACACCATCTGCGAGATCCCGAGCTTCCTCGGCAGCGCCGAGGCTCCCGTCACGCGCCTGGCCCAGCGCCTC
GCGGGCGAGGCCGGCACCACGCTCGTCGCCTTCGGCACCGAAGCCGGCCTCTTCAAGAATGCCGGCATCTCCACCGTGGT
CTGCGGCCCGGGCAGCATCCGGCAGGCCCACCAGCCCGATGAATACGTGAGCCTGGAGCAACTGGCCCGCTGCGAGGCCT
TCATGCGCGGCCTGGCGCAGACGCGCGCACTCGAGGGCTAG

Upstream 100 bases:

>100_bases
TGACGATGGAGTCGATGAGTTTCATAATGGATGCTTCCTTGGTCCAGAGAGTCTAGCCCTGCCTCCGCACGCGCACCAGA
CAGGGTTATTCCACCCCACG

Downstream 100 bases:

>100_bases
ACCTTCACCCGTCCGTCGCCGGTCAGCATCGACATCTCGACGAAGCGCGAGCCCGCGTGGCTGCTGCCGCTGAAGCTGAT
CGGATAGCCCGAGACCGTCG

Product: acetylornithine deacetylase

Products: NA

Alternate protein names: AO; Acetylornithinase; N-acetylornithinase; NAO [H]

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MLSEHALSLAQALVRMNTVSHRSNLELIDFIRTELDRLGVKCRLTYDASKTKANLFATLGEGKPAGIILSGHTDTVPWDG
QDWSMDPLSATVQGGRLHGRGSADMKAFIAIALSQARQFLESDAPFAIHYAFSYDEEVGCFGARELIADMREAGVRPLAC
IVGEPTDMVPAIAHKGVYRYRCCVRGKEAHSSLTPHSVNAIEMAARVVGRVRDMAEGFEREEPRWDGFDVPFSTASVGQF
HGGIADNVVPRDAEFRYEFRDLPTADAARMQAEVVAYARWLEPAMQAVAPQAGITFDTICEIPSFLGSAEAPVTRLAQRL
AGEAGTTLVAFGTEAGLFKNAGISTVVCGPGSIRQAHQPDEYVSLEQLARCEAFMRGLAQTRALEG

Sequences:

>Translated_386_residues
MLSEHALSLAQALVRMNTVSHRSNLELIDFIRTELDRLGVKCRLTYDASKTKANLFATLGEGKPAGIILSGHTDTVPWDG
QDWSMDPLSATVQGGRLHGRGSADMKAFIAIALSQARQFLESDAPFAIHYAFSYDEEVGCFGARELIADMREAGVRPLAC
IVGEPTDMVPAIAHKGVYRYRCCVRGKEAHSSLTPHSVNAIEMAARVVGRVRDMAEGFEREEPRWDGFDVPFSTASVGQF
HGGIADNVVPRDAEFRYEFRDLPTADAARMQAEVVAYARWLEPAMQAVAPQAGITFDTICEIPSFLGSAEAPVTRLAQRL
AGEAGTTLVAFGTEAGLFKNAGISTVVCGPGSIRQAHQPDEYVSLEQLARCEAFMRGLAQTRALEG
>Mature_386_residues
MLSEHALSLAQALVRMNTVSHRSNLELIDFIRTELDRLGVKCRLTYDASKTKANLFATLGEGKPAGIILSGHTDTVPWDG
QDWSMDPLSATVQGGRLHGRGSADMKAFIAIALSQARQFLESDAPFAIHYAFSYDEEVGCFGARELIADMREAGVRPLAC
IVGEPTDMVPAIAHKGVYRYRCCVRGKEAHSSLTPHSVNAIEMAARVVGRVRDMAEGFEREEPRWDGFDVPFSTASVGQF
HGGIADNVVPRDAEFRYEFRDLPTADAARMQAEVVAYARWLEPAMQAVAPQAGITFDTICEIPSFLGSAEAPVTRLAQRL
AGEAGTTLVAFGTEAGLFKNAGISTVVCGPGSIRQAHQPDEYVSLEQLARCEAFMRGLAQTRALEG

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. ArgE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790395, Length=346, Percent_Identity=32.0809248554913, Blast_Score=166, Evalue=2e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010169
- InterPro:   IPR001261
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.16 [H]

Molecular weight: Translated: 41910; Mature: 41910

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSEHALSLAQALVRMNTVSHRSNLELIDFIRTELDRLGVKCRLTYDASKTKANLFATLG
CCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEEEC
EGKPAGIILSGHTDTVPWDGQDWSMDPLSATVQGGRLHGRGSADMKAFIAIALSQARQFL
CCCCCEEEEECCCCCCCCCCCCCCCCCHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHH
ESDAPFAIHYAFSYDEEVGCFGARELIADMREAGVRPLACIVGEPTDMVPAIAHKGVYRY
HCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHCCHHEE
RCCVRGKEAHSSLTPHSVNAIEMAARVVGRVRDMAEGFEREEPRWDGFDVPFSTASVGQF
HHHHCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHH
HGGIADNVVPRDAEFRYEFRDLPTADAARMQAEVVAYARWLEPAMQAVAPQAGITFDTIC
CCCCCCCCCCCCCHHEEHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
EIPSFLGSAEAPVTRLAQRLAGEAGTTLVAFGTEAGLFKNAGISTVVCGPGSIRQAHQPD
HHHHHHCCCCCHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCEEEECCCCCCCCCCCH
EYVSLEQLARCEAFMRGLAQTRALEG
HHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLSEHALSLAQALVRMNTVSHRSNLELIDFIRTELDRLGVKCRLTYDASKTKANLFATLG
CCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEEEC
EGKPAGIILSGHTDTVPWDGQDWSMDPLSATVQGGRLHGRGSADMKAFIAIALSQARQFL
CCCCCEEEEECCCCCCCCCCCCCCCCCHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHH
ESDAPFAIHYAFSYDEEVGCFGARELIADMREAGVRPLACIVGEPTDMVPAIAHKGVYRY
HCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHCCHHEE
RCCVRGKEAHSSLTPHSVNAIEMAARVVGRVRDMAEGFEREEPRWDGFDVPFSTASVGQF
HHHHCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHH
HGGIADNVVPRDAEFRYEFRDLPTADAARMQAEVVAYARWLEPAMQAVAPQAGITFDTIC
CCCCCCCCCCCCCHHEEHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
EIPSFLGSAEAPVTRLAQRLAGEAGTTLVAFGTEAGLFKNAGISTVVCGPGSIRQAHQPD
HHHHHHCCCCCHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCEEEECCCCCCCCCCCH
EYVSLEQLARCEAFMRGLAQTRALEG
HHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9829957 [H]