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The map label for this gene is glpR [H]

Identifier: 120609303

GI number: 120609303

Start: 660436

End: 661200

Strand: Reverse

Name: glpR [H]

Synonym: Aave_0603

Alternate gene names: 120609303

Gene position: 661200-660436 (Counterclockwise)

Preceding gene: 120609329

Following gene: 120609302

Centisome position: 12.35

GC content: 69.15

Gene sequence:

>765_bases
GTGAACACCAATCCCCGACAGCTCCTGCTTCTCGAAGAAGTCCGCGCCCGCCAGACGGCCACGGTCGAACAGCTTGCGGA
TACGCTGGGCGTGACCCTGCAGACCGTGCGCCGCGACATCCAGAAGCTCGCCGACAGCGGTTTGCTGCTGCGCTTCCACG
GCGGCGTGCGGGTGCCCAGCTCCACCACGGAGAACCTGGGCCACACCCAGCGTGAAACCCTGCATGCCGAAGGCAAGGCG
CGCATCGCCCGGGCCGTGGCCCAGGCAGTGCCGCACAACTGCTCGCTGATCCTGAACATCGGCACCACCACCGAGGCGAT
CGCGCGGGCGCTGCTGCACCACCGGGGGCTGCGCGTGATCACGAACAACCTGAACGTGGCGGCGATCCTGGCGGGCAATC
CGGACTGCGAAGTGATCGTGGCCGGCGGCGTGGTGCGTGCGCGGGACCGCGGCATCGTGGGCGAGGCGGCGGTGGACTTC
ATCCGCCAGTTCAAGGTGGACATCGCGCTCATCGGCATCTCGGGCATCGAGCCGGACGGCTCGCTGCGCGACTTCGACCT
GCGGGAAGTGAAAGTGGCGCAGACCATCATCGCCCAGGCCCGCGAGGTGTGGCTGGCCACGGACCACAGCAAGTTCGACC
GGCCCGCCATGGTGCAGGTGGCGACCCTGGCGCAGATCGACCGGCTCTTCACGGACGCGCGCCCCCCCGATCCCTTTCCT
GCCCTGCTGCGCGACGCCGGGGTGGAACTCGACGTGGCGGAGTGA

Upstream 100 bases:

>100_bases
TTGCCTCCAGGTTTACCCTTGGTTTTTTCTTTTTCGTTCGTTTTAAAGTCGGGTCTCTGCCGTTCCGAACCTTTTCCACG
GACGGCCACCCTACCCTCGC

Downstream 100 bases:

>100_bases
GCCCGCCATCTCCCCCTCCCATTTCAACATCGCATACCCCCCGGACGCCATGACCTATCTGCTCGCCCTCGACCAAGGCA
CCTCCAGCTCGCGCAGCATC

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MNTNPRQLLLLEEVRARQTATVEQLADTLGVTLQTVRRDIQKLADSGLLLRFHGGVRVPSSTTENLGHTQRETLHAEGKA
RIARAVAQAVPHNCSLILNIGTTTEAIARALLHHRGLRVITNNLNVAAILAGNPDCEVIVAGGVVRARDRGIVGEAAVDF
IRQFKVDIALIGISGIEPDGSLRDFDLREVKVAQTIIAQAREVWLATDHSKFDRPAMVQVATLAQIDRLFTDARPPDPFP
ALLRDAGVELDVAE

Sequences:

>Translated_254_residues
MNTNPRQLLLLEEVRARQTATVEQLADTLGVTLQTVRRDIQKLADSGLLLRFHGGVRVPSSTTENLGHTQRETLHAEGKA
RIARAVAQAVPHNCSLILNIGTTTEAIARALLHHRGLRVITNNLNVAAILAGNPDCEVIVAGGVVRARDRGIVGEAAVDF
IRQFKVDIALIGISGIEPDGSLRDFDLREVKVAQTIIAQAREVWLATDHSKFDRPAMVQVATLAQIDRLFTDARPPDPFP
ALLRDAGVELDVAE
>Mature_254_residues
MNTNPRQLLLLEEVRARQTATVEQLADTLGVTLQTVRRDIQKLADSGLLLRFHGGVRVPSSTTENLGHTQRETLHAEGKA
RIARAVAQAVPHNCSLILNIGTTTEAIARALLHHRGLRVITNNLNVAAILAGNPDCEVIVAGGVVRARDRGIVGEAAVDF
IRQFKVDIALIGISGIEPDGSLRDFDLREVKVAQTIIAQAREVWLATDHSKFDRPAMVQVATLAQIDRLFTDARPPDPFP
ALLRDAGVELDVAE

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=253, Percent_Identity=43.8735177865613, Blast_Score=224, Evalue=4e-60,
Organism=Escherichia coli, GI87082344, Length=247, Percent_Identity=42.5101214574899, Blast_Score=204, Evalue=5e-54,
Organism=Escherichia coli, GI1788069, Length=234, Percent_Identity=30.3418803418803, Blast_Score=120, Evalue=6e-29,
Organism=Escherichia coli, GI226510968, Length=249, Percent_Identity=30.9236947791165, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1789519, Length=250, Percent_Identity=26, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1789059, Length=252, Percent_Identity=26.5873015873016, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1790753, Length=244, Percent_Identity=27.8688524590164, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI1787063, Length=235, Percent_Identity=27.6595744680851, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1787540, Length=233, Percent_Identity=27.0386266094421, Blast_Score=77, Evalue=7e-16,
Organism=Escherichia coli, GI1789170, Length=232, Percent_Identity=23.2758620689655, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1790635, Length=148, Percent_Identity=33.7837837837838, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 27611; Mature: 27611

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTNPRQLLLLEEVRARQTATVEQLADTLGVTLQTVRRDIQKLADSGLLLRFHGGVRVPS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCEECCC
STTENLGHTQRETLHAEGKARIARAVAQAVPHNCSLILNIGTTTEAIARALLHHRGLRVI
CCHHHCCCHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCCCEEE
TNNLNVAAILAGNPDCEVIVAGGVVRARDRGIVGEAAVDFIRQFKVDIALIGISGIEPDG
ECCCCEEEEEECCCCCEEEEECCEEEECCCCCCHHHHHHHHHHHHHEEEEEEECCCCCCC
SLRDFDLREVKVAQTIIAQAREVWLATDHSKFDRPAMVQVATLAQIDRLFTDARPPDPFP
CCCCCCHHHHHHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHH
ALLRDAGVELDVAE
HHHHHCCCEEEECC
>Mature Secondary Structure
MNTNPRQLLLLEEVRARQTATVEQLADTLGVTLQTVRRDIQKLADSGLLLRFHGGVRVPS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCEECCC
STTENLGHTQRETLHAEGKARIARAVAQAVPHNCSLILNIGTTTEAIARALLHHRGLRVI
CCHHHCCCHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCCCEEE
TNNLNVAAILAGNPDCEVIVAGGVVRARDRGIVGEAAVDFIRQFKVDIALIGISGIEPDG
ECCCCEEEEEECCCCCEEEEECCEEEECCCCCCHHHHHHHHHHHHHEEEEEEECCCCCCC
SLRDFDLREVKVAQTIIAQAREVWLATDHSKFDRPAMVQVATLAQIDRLFTDARPPDPFP
CCCCCCHHHHHHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHH
ALLRDAGVELDVAE
HHHHHCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8752340; 10984043 [H]