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The map label for this gene is tsr [H]

Identifier: 120609124

GI number: 120609124

Start: 453036

End: 454892

Strand: Reverse

Name: tsr [H]

Synonym: Aave_0421

Alternate gene names: 120609124

Gene position: 454892-453036 (Counterclockwise)

Preceding gene: 120609127

Following gene: 120609123

Centisome position: 8.5

GC content: 69.95

Gene sequence:

>1857_bases
ATGTTCCATAGCCTTCGCGCCCGCCTCATCGGGATCTGCATCGCCATCACCGCCCTGTCGCTCATCGCGCTGGCGCTGGC
CACCTTCTTCGTCGTGCGCGGCAATACGCTTTCAGGCCTGGACGAACGCATCGGCCAGCTCACGCGCCTGCATGCCGGCG
AACTGACCGAGTGGGTCAAGGAAAAGCAGCGCATCACCTCTTCCCTGAAAACGGCCGTCGGCCAGGCCGAGCCGGTGCCC
TTCCTCCTCGCGGCCAAGCAGGCCGGCGCGTTCGACGACACCTACTTCGTCTATGCCGACAAGCGCAACATCTTCGCGCA
CCCCATGCCGGAGGGCTATGACGGCACCGCGCGCCCCTGGTACAGGCAGGCGGTCCAGGCCGGCGGACCGGCCCTCACGC
CGGCCTACGTGGACGCCAGCACGGGCAAGCTCACCATCAGCTTCGTCGAGCCCGTCGGTCCCGCCGGACAACCCACCGCC
GTCATCGGCACCGACATGCACCTGGACACCGTGACCCGCAAGGTCAACGCGATCCACCCCATGGAGAAGAGCTTCGCCTT
CCTGCTGGACGGGCAGGGCAACATCCTCGCGCATGCCAAGGCCGAACTGGCCCTGAAGCCCGTCACCGCGATCTCCCCGG
CCCTGGACGGGGCGCAGATCGCGCGACTCGCTTCGGACGGCGGACGTGCCGACATCTCCATCGACGACGCCCCCACCATG
CTCTATGCCGCGAAGGTGGAAGGCACGCCCTGGATCCTGGCCATCGCCATCGACCGCGCCGAAGCCACCCGCCCCGTGCG
CGAACTCCTCAACGTCGCCGTCGCCATCACCGTGCTGTGCATGCTCGCCGCCGTCGGCCTGCTCACCTACGCCGTCAGCC
GCCAGCTGCGCCGCCTCGCCGTCGTGCGCGACGCCCTGGAGGACATCGCATCCGGCGAAGGCGACCTCACCCGCCGCCTC
GACACCCACGGCAGCGACGAGCTCACCCAGATCTCCCGCGCCTTCAACCACTTCGTGGACAAGATCGCCGCCGTCCTCGT
GCGCATCCGCGCCTCCTCCGAAGCCGTGCGCCTGGCCACCAGCGAGATCGCCAGCGGCAACCAGGACCTCTCCGGCCGCA
CCGAGCAGCAGGCCAGCTCCCTGGAGGAGACCGCCGCCGCCATGGAACAGCTCACCGCCACCGTCCAGCAGAACGCCGAG
AACGCCCGCCAGGCCAACCACCTGGCCGCCAACGCTTCGCAGATCGCCGCCCACGGCGGCACCGTCGTCGGCCAGGTCGT
GCAGACCATGGGCGGCATCGATGCCTCCTCGCGCAAGATCGTGGACATCATCGGCGTCATCGATTCCATCGCCTTCCAGA
CCAACATCCTCGCCCTCAACGCCGCCGTCGAGGCCGCACGCGCCGGCGAGCAGGGCCGGGGTTTCGCCGTCGTCGCCTCC
GAGGTCCGCACCCTCGCGCAGCGATCGGCCACCGCCGCCAAGGAGATCAAGTCCCTCATCGACGACTCCGTGCAGCAGGT
CAACGCCGGCAGCCGCCTCGTGCAGGACGCCGGCTCCACCATGCAGGAGGTCGTCGAGAGCGTGCAGCGCGTCACCGCCA
TCGTCGCCGAGATCAGCAGCGCCAGCCAGGAGCAGAGCACCGGCATCGCCGAGATCGGCAGCGCCGTCAGCCAGATGGAC
CAGAGCACCCAGCAGAACGCCGCCCTCGTCGAGCAGGCCACCGCCGCCGCCCAGTCGCTGCAGCAGCAGGCCCACCAGCT
CGCCGATGCCGTGGCCGGCTTCAGGCTCGAGGCCCATGGCTCCGCCACCCACGCGCCACGCCATCCGGCGCTCGGCGCGC
CTGCCGGACGCGCCTGA

Upstream 100 bases:

>100_bases
TCCACCATGCAGAACAAATGTTTCATTCTGTTGATAAAGTTCAGCAATAAACGATAACCGGCGATCCCCCTGCCACAGGC
CGTCCCCCTGGAGTCCGTCG

Downstream 100 bases:

>100_bases
AAAGGTACTCGCGGCCGTGGCTGGCACGGCAGGCGCCGTGGCGGCGATGATGGAGGCATGATGACCTCCCCATCCACTCC
ACCCTCCCCCGCCACGGCCA

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: MCP-I; Serine chemoreceptor protein [H]

Number of amino acids: Translated: 618; Mature: 618

Protein sequence:

>618_residues
MFHSLRARLIGICIAITALSLIALALATFFVVRGNTLSGLDERIGQLTRLHAGELTEWVKEKQRITSSLKTAVGQAEPVP
FLLAAKQAGAFDDTYFVYADKRNIFAHPMPEGYDGTARPWYRQAVQAGGPALTPAYVDASTGKLTISFVEPVGPAGQPTA
VIGTDMHLDTVTRKVNAIHPMEKSFAFLLDGQGNILAHAKAELALKPVTAISPALDGAQIARLASDGGRADISIDDAPTM
LYAAKVEGTPWILAIAIDRAEATRPVRELLNVAVAITVLCMLAAVGLLTYAVSRQLRRLAVVRDALEDIASGEGDLTRRL
DTHGSDELTQISRAFNHFVDKIAAVLVRIRASSEAVRLATSEIASGNQDLSGRTEQQASSLEETAAAMEQLTATVQQNAE
NARQANHLAANASQIAAHGGTVVGQVVQTMGGIDASSRKIVDIIGVIDSIAFQTNILALNAAVEAARAGEQGRGFAVVAS
EVRTLAQRSATAAKEIKSLIDDSVQQVNAGSRLVQDAGSTMQEVVESVQRVTAIVAEISSASQEQSTGIAEIGSAVSQMD
QSTQQNAALVEQATAAAQSLQQQAHQLADAVAGFRLEAHGSATHAPRHPALGAPAGRA

Sequences:

>Translated_618_residues
MFHSLRARLIGICIAITALSLIALALATFFVVRGNTLSGLDERIGQLTRLHAGELTEWVKEKQRITSSLKTAVGQAEPVP
FLLAAKQAGAFDDTYFVYADKRNIFAHPMPEGYDGTARPWYRQAVQAGGPALTPAYVDASTGKLTISFVEPVGPAGQPTA
VIGTDMHLDTVTRKVNAIHPMEKSFAFLLDGQGNILAHAKAELALKPVTAISPALDGAQIARLASDGGRADISIDDAPTM
LYAAKVEGTPWILAIAIDRAEATRPVRELLNVAVAITVLCMLAAVGLLTYAVSRQLRRLAVVRDALEDIASGEGDLTRRL
DTHGSDELTQISRAFNHFVDKIAAVLVRIRASSEAVRLATSEIASGNQDLSGRTEQQASSLEETAAAMEQLTATVQQNAE
NARQANHLAANASQIAAHGGTVVGQVVQTMGGIDASSRKIVDIIGVIDSIAFQTNILALNAAVEAARAGEQGRGFAVVAS
EVRTLAQRSATAAKEIKSLIDDSVQQVNAGSRLVQDAGSTMQEVVESVQRVTAIVAEISSASQEQSTGIAEIGSAVSQMD
QSTQQNAALVEQATAAAQSLQQQAHQLADAVAGFRLEAHGSATHAPRHPALGAPAGRA
>Mature_618_residues
MFHSLRARLIGICIAITALSLIALALATFFVVRGNTLSGLDERIGQLTRLHAGELTEWVKEKQRITSSLKTAVGQAEPVP
FLLAAKQAGAFDDTYFVYADKRNIFAHPMPEGYDGTARPWYRQAVQAGGPALTPAYVDASTGKLTISFVEPVGPAGQPTA
VIGTDMHLDTVTRKVNAIHPMEKSFAFLLDGQGNILAHAKAELALKPVTAISPALDGAQIARLASDGGRADISIDDAPTM
LYAAKVEGTPWILAIAIDRAEATRPVRELLNVAVAITVLCMLAAVGLLTYAVSRQLRRLAVVRDALEDIASGEGDLTRRL
DTHGSDELTQISRAFNHFVDKIAAVLVRIRASSEAVRLATSEIASGNQDLSGRTEQQASSLEETAAAMEQLTATVQQNAE
NARQANHLAANASQIAAHGGTVVGQVVQTMGGIDASSRKIVDIIGVIDSIAFQTNILALNAAVEAARAGEQGRGFAVVAS
EVRTLAQRSATAAKEIKSLIDDSVQQVNAGSRLVQDAGSTMQEVVESVQRVTAIVAEISSASQEQSTGIAEIGSAVSQMD
QSTQQNAALVEQATAAAQSLQQQAHQLADAVAGFRLEAHGSATHAPRHPALGAPAGRA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=365, Percent_Identity=53.972602739726, Blast_Score=309, Evalue=3e-85,
Organism=Escherichia coli, GI1788195, Length=297, Percent_Identity=58.5858585858586, Blast_Score=298, Evalue=8e-82,
Organism=Escherichia coli, GI1787690, Length=323, Percent_Identity=53.8699690402477, Blast_Score=294, Evalue=1e-80,
Organism=Escherichia coli, GI1788194, Length=306, Percent_Identity=54.9019607843137, Blast_Score=290, Evalue=2e-79,
Organism=Escherichia coli, GI1789453, Length=321, Percent_Identity=39.2523364485981, Blast_Score=200, Evalue=3e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 64961; Mature: 64961

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFHSLRARLIGICIAITALSLIALALATFFVVRGNTLSGLDERIGQLTRLHAGELTEWVK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
EKQRITSSLKTAVGQAEPVPFLLAAKQAGAFDDTYFVYADKRNIFAHPMPEGYDGTARPW
HHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCHH
YRQAVQAGGPALTPAYVDASTGKLTISFVEPVGPAGQPTAVIGTDMHLDTVTRKVNAIHP
HHHHHHCCCCCCCCCEEECCCCEEEEEEECCCCCCCCCCEEEECCCHHHHHHHHHHHCCC
MEKSFAFLLDGQGNILAHAKAELALKPVTAISPALDGAQIARLASDGGRADISIDDAPTM
HHHCEEEEECCCCCEEEECHHHHHCCCHHHHCCCCCHHHHHHHHCCCCCEEEEECCCCCE
LYAAKVEGTPWILAIAIDRAEATRPVRELLNVAVAITVLCMLAAVGLLTYAVSRQLRRLA
EEEEEECCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVRDALEDIASGEGDLTRRLDTHGSDELTQISRAFNHFVDKIAAVLVRIRASSEAVRLAT
HHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
SEIASGNQDLSGRTEQQASSLEETAAAMEQLTATVQQNAENARQANHLAANASQIAAHGG
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCC
TVVGQVVQTMGGIDASSRKIVDIIGVIDSIAFQTNILALNAAVEAARAGEQGRGFAVVAS
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
EVRTLAQRSATAAKEIKSLIDDSVQQVNAGSRLVQDAGSTMQEVVESVQRVTAIVAEISS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASQEQSTGIAEIGSAVSQMDQSTQQNAALVEQATAAAQSLQQQAHQLADAVAGFRLEAHG
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECC
SATHAPRHPALGAPAGRA
CCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MFHSLRARLIGICIAITALSLIALALATFFVVRGNTLSGLDERIGQLTRLHAGELTEWVK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
EKQRITSSLKTAVGQAEPVPFLLAAKQAGAFDDTYFVYADKRNIFAHPMPEGYDGTARPW
HHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCHH
YRQAVQAGGPALTPAYVDASTGKLTISFVEPVGPAGQPTAVIGTDMHLDTVTRKVNAIHP
HHHHHHCCCCCCCCCEEECCCCEEEEEEECCCCCCCCCCEEEECCCHHHHHHHHHHHCCC
MEKSFAFLLDGQGNILAHAKAELALKPVTAISPALDGAQIARLASDGGRADISIDDAPTM
HHHCEEEEECCCCCEEEECHHHHHCCCHHHHCCCCCHHHHHHHHCCCCCEEEEECCCCCE
LYAAKVEGTPWILAIAIDRAEATRPVRELLNVAVAITVLCMLAAVGLLTYAVSRQLRRLA
EEEEEECCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVRDALEDIASGEGDLTRRLDTHGSDELTQISRAFNHFVDKIAAVLVRIRASSEAVRLAT
HHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
SEIASGNQDLSGRTEQQASSLEETAAAMEQLTATVQQNAENARQANHLAANASQIAAHGG
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCC
TVVGQVVQTMGGIDASSRKIVDIIGVIDSIAFQTNILALNAAVEAARAGEQGRGFAVVAS
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
EVRTLAQRSATAAKEIKSLIDDSVQQVNAGSRLVQDAGSTMQEVVESVQRVTAIVAEISS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASQEQSTGIAEIGSAVSQMDQSTQQNAALVEQATAAAQSLQQQAHQLADAVAGFRLEAHG
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECC
SATHAPRHPALGAPAGRA
CCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6402709; 7610040; 9278503; 8384293; 6213619; 2033064; 10466731 [H]