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The map label for this gene is yafC [H]

Identifier: 120608988

GI number: 120608988

Start: 316949

End: 317845

Strand: Reverse

Name: yafC [H]

Synonym: Aave_0285

Alternate gene names: 120608988

Gene position: 317845-316949 (Counterclockwise)

Preceding gene: 120608991

Following gene: 120608987

Centisome position: 5.94

GC content: 72.24

Gene sequence:

>897_bases
ATGAAAACCACCCTGGAAGAACTGCAGGCCTTCGCCGCCGTGGTGGACGCAGGCTCGGTCACCGCCGCCGCTGCGCAACT
GGAGCAGACGGCATCGGGCGTCAGCCGGGCGCTGGCACGCCTGGAGAAAAAGCTCGACACGACGCTGCTGCGCCGTACCA
CGCGCCGCATCGGGCTCACGGAGGAAGGCCAGGCCTTCCTCACGCGCACCCGCGCGATCCTCGCGGCGCTCGACGAAGCG
GAAGAGCACATGGCCGCGCGCCGGGGGCAGCCCGCGGGACGCCTGCGCGTGAACGCGGCCACGCCGTTCATGCTTCACGT
GGTGGCACCGCTGGTGCCGGCCTTCCGCGACGCCTACCCGCAGATCGCCCTGGAGCTGGACACCGACGAGCGCAACATCG
ACCTGCTGGAGCGGCGCACGGACGTCGCCATCCGCATCGGTGCCCTGCGCGACTCCACGCTGCATGCGCGCCCGCTGGGC
TCCAGCCGCCTGCGCGTGCTCGCCAGCCCTGCCTACGTGGCCACGCACGGCCGGCCGAAGTCGGCAGCGGCCCTGGCGCA
GCACACCCTGCTGGGGTTCACCCAGCCCGAGGCGCTCAACCTCTGGCCCCTGCGCGGCCCGCACGGCGACGCATGGGCCG
CCACGCCGGACATCGCGGCCTCCAGCGGCGAAACCCTGCGCCAGCTCGCGCTGCAGGGCACCGGCATCGCCTGCCTGGCG
GACTTCATGACCGCGCGGGACCGCGAGCGCGGCGACCTCGTACAACTGCTGGCCCGGGACACGGCCGATGTGCGGCAGCC
CATCAGCGCGGTGTACTACCGCAACACGCAGCTCGCTTCGCGCATCGCCTGCTTCCTGGATTTCCTGGCCGCACGGCTGG
CCGAACCCGGACATTGA

Upstream 100 bases:

>100_bases
GGGATCACAGATCGATGCCAGGAGTGTGGGTGCTTCACCTTTGCGGAAAAAGCCTGTGATCGGCAGAATATATTTGCCTT
AGAGTCAACAATCCATCCTC

Downstream 100 bases:

>100_bases
GAAAACCCTGTAGGACCGCATCGGGTCCTGCGGGCAGGCTTGCGCGAGCGCAAGGCCGCGCGACCCGGCGGCGCTTCAAT
GGCGCCATGCGCACCAAGGA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MKTTLEELQAFAAVVDAGSVTAAAAQLEQTASGVSRALARLEKKLDTTLLRRTTRRIGLTEEGQAFLTRTRAILAALDEA
EEHMAARRGQPAGRLRVNAATPFMLHVVAPLVPAFRDAYPQIALELDTDERNIDLLERRTDVAIRIGALRDSTLHARPLG
SSRLRVLASPAYVATHGRPKSAAALAQHTLLGFTQPEALNLWPLRGPHGDAWAATPDIAASSGETLRQLALQGTGIACLA
DFMTARDRERGDLVQLLARDTADVRQPISAVYYRNTQLASRIACFLDFLAARLAEPGH

Sequences:

>Translated_298_residues
MKTTLEELQAFAAVVDAGSVTAAAAQLEQTASGVSRALARLEKKLDTTLLRRTTRRIGLTEEGQAFLTRTRAILAALDEA
EEHMAARRGQPAGRLRVNAATPFMLHVVAPLVPAFRDAYPQIALELDTDERNIDLLERRTDVAIRIGALRDSTLHARPLG
SSRLRVLASPAYVATHGRPKSAAALAQHTLLGFTQPEALNLWPLRGPHGDAWAATPDIAASSGETLRQLALQGTGIACLA
DFMTARDRERGDLVQLLARDTADVRQPISAVYYRNTQLASRIACFLDFLAARLAEPGH
>Mature_298_residues
MKTTLEELQAFAAVVDAGSVTAAAAQLEQTASGVSRALARLEKKLDTTLLRRTTRRIGLTEEGQAFLTRTRAILAALDEA
EEHMAARRGQPAGRLRVNAATPFMLHVVAPLVPAFRDAYPQIALELDTDERNIDLLERRTDVAIRIGALRDSTLHARPLG
SSRLRVLASPAYVATHGRPKSAAALAQHTLLGFTQPEALNLWPLRGPHGDAWAATPDIAASSGETLRQLALQGTGIACLA
DFMTARDRERGDLVQLLARDTADVRQPISAVYYRNTQLASRIACFLDFLAARLAEPGH

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=290, Percent_Identity=46.2068965517241, Blast_Score=277, Evalue=6e-76,
Organism=Escherichia coli, GI1789639, Length=296, Percent_Identity=32.0945945945946, Blast_Score=144, Evalue=5e-36,
Organism=Escherichia coli, GI87081978, Length=297, Percent_Identity=31.986531986532, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1789440, Length=297, Percent_Identity=28.2828282828283, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI145693193, Length=296, Percent_Identity=29.0540540540541, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1787128, Length=297, Percent_Identity=26.2626262626263, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1787589, Length=293, Percent_Identity=25.938566552901, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1789173, Length=260, Percent_Identity=30.7692307692308, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1788481, Length=295, Percent_Identity=24.0677966101695, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1786448, Length=271, Percent_Identity=26.1992619926199, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI87082132, Length=250, Percent_Identity=24.8, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1787806, Length=171, Percent_Identity=27.4853801169591, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1787879, Length=162, Percent_Identity=32.0987654320988, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32294; Mature: 32294

Theoretical pI: Translated: 9.19; Mature: 9.19

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTTLEELQAFAAVVDAGSVTAAAAQLEQTASGVSRALARLEKKLDTTLLRRTTRRIGLT
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
EEGQAFLTRTRAILAALDEAEEHMAARRGQPAGRLRVNAATPFMLHVVAPLVPAFRDAYP
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCC
QIALELDTDERNIDLLERRTDVAIRIGALRDSTLHARPLGSSRLRVLASPAYVATHGRPK
CEEEEECCCCCCHHHHHHCCCEEEEEECCCCCCCCCCCCCCCHHEEEECCCEEEECCCCH
SAAALAQHTLLGFTQPEALNLWPLRGPHGDAWAATPDIAASSGETLRQLALQGTGIACLA
HHHHHHHHHHHCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHH
DFMTARDRERGDLVQLLARDTADVRQPISAVYYRNTQLASRIACFLDFLAARLAEPGH
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKTTLEELQAFAAVVDAGSVTAAAAQLEQTASGVSRALARLEKKLDTTLLRRTTRRIGLT
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
EEGQAFLTRTRAILAALDEAEEHMAARRGQPAGRLRVNAATPFMLHVVAPLVPAFRDAYP
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCC
QIALELDTDERNIDLLERRTDVAIRIGALRDSTLHARPLGSSRLRVLASPAYVATHGRPK
CEEEEECCCCCCHHHHHHCCCEEEEEECCCCCCCCCCCCCCCHHEEEECCCEEEECCCCH
SAAALAQHTLLGFTQPEALNLWPLRGPHGDAWAATPDIAASSGETLRQLALQGTGIACLA
HHHHHHHHHHHCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHH
DFMTARDRERGDLVQLLARDTADVRQPISAVYYRNTQLASRIACFLDFLAARLAEPGH
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]