Click here to switch to the map view.

The map label for this gene is ycbL [H]

Identifier: 120608985

GI number: 120608985

Start: 314233

End: 314955

Strand: Reverse

Name: ycbL [H]

Synonym: Aave_0282

Alternate gene names: 120608985

Gene position: 314955-314233 (Counterclockwise)

Preceding gene: 120608987

Following gene: 120608984

Centisome position: 5.88

GC content: 70.82

Gene sequence:

>723_bases
ATGGCCAGGCGGCGTCCTTCCATCGGCGGGCGGCATACTCGGCCTCTCGCCCACCCCTTGTGCCGGCCCTCGTCTTCAGT
TCCCATGCTCCACTACCACACCCACCCCGTCACCGCCTTCCAGCAGAACTGCTCGCTTGTCTGGTGCGATGCCACGCAGG
CGGCCGCCGTGATCGACCCCGGCGGCGACCTCGACCAGGTGCTCGCGGAGGTGGAGCGCCGCGGCCTGCGGCTGGAGCAG
ATCTGGCTGACGCACGCCCACATCGACCATGCCGGCGGCGCGGGCGAACTGGCCGAGCGGCTCTCGCTGCCGATCACGGG
CCCCCACCCGGGCGACCAGTTCTGGATCGACGGGCTGCCGCAGCAGAGCGCGATGTTCGGGTTCCCGCCCGCCCGGCCCT
TCACGCCCACGCGCTGGCTGCACGACGGCGACACGGTGCAGATCGGCAACGAGACGCTGCACGTGCGGCACTGCCCTGGC
CACACGCCTGGCCACGTGGTGTTCCATGCGCCGCAGATCCAGCGCTGCTTCGTGGGGGACGTGCTGTTCGCCGGCAGCAT
CGGCCGCACGGACTTCCCCCAGGGCAACCACCAGGACCTGATCGACAGCATCGTGCAGCGCCTGTGGCCCATGGGCGACG
AGACGGTGTTCATTCCCGGCCACGGGCCGGAGAGCACCTTCGGGCGCGAACGGCGCAGCAATCCCTACGTGGGCGGCACC
TGA

Upstream 100 bases:

>100_bases
TTCACCCCATCGGGTCGCGAGAATGAATGAAAGCCTTCCATGGCCCCGGGGCATGGCGGTTCTTTCGGGAAAGGGGGGAT
TCTAGGGCGCTGCGTGGGCG

Downstream 100 bases:

>100_bases
GCGGCCCTCCACGGCCGGGTATCCGCCCGGCCTTGATGCCGGTCAACGTCCCGAGAGCGGGGTACGGGCATTCTTCCAGG
CAGGCCTGATGGCACCGCGC

Product: beta-lactamase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 239

Protein sequence:

>240_residues
MARRRPSIGGRHTRPLAHPLCRPSSSVPMLHYHTHPVTAFQQNCSLVWCDATQAAAVIDPGGDLDQVLAEVERRGLRLEQ
IWLTHAHIDHAGGAGELAERLSLPITGPHPGDQFWIDGLPQQSAMFGFPPARPFTPTRWLHDGDTVQIGNETLHVRHCPG
HTPGHVVFHAPQIQRCFVGDVLFAGSIGRTDFPQGNHQDLIDSIVQRLWPMGDETVFIPGHGPESTFGRERRSNPYVGGT

Sequences:

>Translated_240_residues
MARRRPSIGGRHTRPLAHPLCRPSSSVPMLHYHTHPVTAFQQNCSLVWCDATQAAAVIDPGGDLDQVLAEVERRGLRLEQ
IWLTHAHIDHAGGAGELAERLSLPITGPHPGDQFWIDGLPQQSAMFGFPPARPFTPTRWLHDGDTVQIGNETLHVRHCPG
HTPGHVVFHAPQIQRCFVGDVLFAGSIGRTDFPQGNHQDLIDSIVQRLWPMGDETVFIPGHGPESTFGRERRSNPYVGGT
>Mature_239_residues
ARRRPSIGGRHTRPLAHPLCRPSSSVPMLHYHTHPVTAFQQNCSLVWCDATQAAAVIDPGGDLDQVLAEVERRGLRLEQI
WLTHAHIDHAGGAGELAERLSLPITGPHPGDQFWIDGLPQQSAMFGFPPARPFTPTRWLHDGDTVQIGNETLHVRHCPGH
TPGHVVFHAPQIQRCFVGDVLFAGSIGRTDFPQGNHQDLIDSIVQRLWPMGDETVFIPGHGPESTFGRERRSNPYVGGT

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=189, Percent_Identity=31.2169312169312, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI116642887, Length=194, Percent_Identity=29.8969072164948, Blast_Score=64, Evalue=9e-11,
Organism=Escherichia coli, GI1787158, Length=208, Percent_Identity=54.8076923076923, Blast_Score=254, Evalue=5e-69,
Organism=Caenorhabditis elegans, GI17538952, Length=197, Percent_Identity=27.4111675126904, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 26468; Mature: 26337

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARRRPSIGGRHTRPLAHPLCRPSSSVPMLHYHTHPVTAFQQNCSLVWCDATQAAAVIDP
CCCCCCCCCCCCCCCHHHHHCCCCCCCCEEEEECCCCHHHHCCCCEEEECCCCCEEEECC
GGDLDQVLAEVERRGLRLEQIWLTHAHIDHAGGAGELAERLSLPITGPHPGDQFWIDGLP
CCCHHHHHHHHHHCCCEEEEEEEEHHEECCCCCHHHHHHHHCCCCCCCCCCCCEEECCCC
QQSAMFGFPPARPFTPTRWLHDGDTVQIGNETLHVRHCPGHTPGHVVFHAPQIQRCFVGD
CCCCCCCCCCCCCCCCCCEECCCCEEEECCEEEEEEECCCCCCCEEEEECCCCCHHHHHH
VLFAGSIGRTDFPQGNHQDLIDSIVQRLWPMGDETVFIPGHGPESTFGRERRSNPYVGGT
HHEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHCHHHCCCCCCCCC
>Mature Secondary Structure 
ARRRPSIGGRHTRPLAHPLCRPSSSVPMLHYHTHPVTAFQQNCSLVWCDATQAAAVIDP
CCCCCCCCCCCCCCHHHHHCCCCCCCCEEEEECCCCHHHHCCCCEEEECCCCCEEEECC
GGDLDQVLAEVERRGLRLEQIWLTHAHIDHAGGAGELAERLSLPITGPHPGDQFWIDGLP
CCCHHHHHHHHHHCCCEEEEEEEEHHEECCCCCHHHHHHHHCCCCCCCCCCCCEEECCCC
QQSAMFGFPPARPFTPTRWLHDGDTVQIGNETLHVRHCPGHTPGHVVFHAPQIQRCFVGD
CCCCCCCCCCCCCCCCCCEECCCCEEEECCEEEEEEECCCCCCCEEEEECCCCCHHHHHH
VLFAGSIGRTDFPQGNHQDLIDSIVQRLWPMGDETVFIPGHGPESTFGRERRSNPYVGGT
HHEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHCHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]