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The map label for this gene is foxA [H]

Identifier: 120608900

GI number: 120608900

Start: 217000

End: 219132

Strand: Reverse

Name: foxA [H]

Synonym: Aave_0192

Alternate gene names: 120608900

Gene position: 219132-217000 (Counterclockwise)

Preceding gene: 120608901

Following gene: 120608899

Centisome position: 4.09

GC content: 71.35

Gene sequence:

>2133_bases
ATGCCCCGCCGCGCCCCGCTGGCGCGGGCCGTGCTGGCACTCGCCGCCAGCCTTTCCGCCCAGCACGTGGCCCACGCGCA
GGAGGCCGCCACGGCCCCTGCGGCCCCCACCGCCACGCTGCAGGAAGTGCGCGTGCAGGATGCCACCGACGGCTCCGGCT
ACCAGGGCGCGCAGCGCCAGACCGCGGCCACGCGCACCGACACGCCCCTGGTCGAGACGCCGCAGGCCGTGCGCGTGGTG
CCGCGCCAGTTGCTCGAAGACCTGGGGGCCAGGCGCCTGGCCGATACGGTGGACTTCGTGAGCGGCGTGACCCGCATGAA
CGACTTCGGCGGTACCTGGGACAACTATGCGATCCGCGGCTTCAGCAACACCGAAGGCGGCTCGCTGCTGAACGGCTTCG
CCTCCGGCCGCGGCTACGGCCCGCAACGCGACGCGGCCACCATCGAGCGGGTGGAGTTCCTCAAGGGCCCGGCCGCCGCG
CTCTACGGCAGCAGCGAGCCCGGCGGCACGCTCAACGTGGTCACCAAGAAGCCGCAGTTCACCGCCGCGCGCACCGCCGG
CCTGCAGATCGGCACGCTGGGCATGCGCCGCGCCACGCTGGACCTGACCGGCCCGGCCACGCAGAACCTGGCCTACCGGC
TGAACGTGGCGGCCGAGGACGGCGCCAGCCGCACGGGCCTCGTGGACAACCGCAAGTACGTGGTCGCCCCCGCCTTCGCC
TGGACGCTGGGCGCCGATACGGTGCTGCAGTACGAGGCGGAGATCATCCGCATCCGCACCCCGCTGGACCGGGGCGTGGT
GCAGGTGAACGGCAACGCCCTGGCCCTGCCCGCCGACCGCTTCCTGCAGGAGCCCGACCGCGGCAACCTGCACGTGAACG
GCGACACGCACCAGCTCACGCTGGACCACGACCTGGGCGGCGGCTGGCGCACGCGCCTGGGCGGCACTTATCGCGAAACC
GAGTTCCACGGCAATGCCGTGGACTTCGGCACGGGCCAGATCGGGCTGCTCGCGGCCAACGGCCGCACGCTGTCGCGCAC
CGACAGCTGGCGCACCCTGCCCTCGCGCGACGTGTCGGTGCAGGCCGAGCTGGAAGGCAAGTTCAGCACCGGCAGCCTGC
GCCACACCGTGCTGGCCGGCCTGGAGTCCTGGCGCCTCTACATGGGGCAGGACATCCGCTATTCCGCGCAGAAATACCCG
ATCGACATCTACGATCCGGTCTATGGCACCGTGCCGCGCGGCCCGCTGGTGCAGGGCTACCTGCAGGACGACCGCCTGCG
CGCCACCGGCCTGTTCCTGCAGGACCAGATCGACCTGACGCCGCGCTGGAAGCTGATGGCCGGCCTGCGCTTCGACCGCT
TCCACGAGGATTTCGTCAACTGGATGACGAATGCGCGCCAGAACCAGCAGCATTCCTCGGCCACGCCGCGCGTGGGCCTG
AGCTACATGGTGACGCCGGACAGCTCGGTGTACGTGTCCTACGGCCGTTCGTTCCGGCCCAATGCCGGCACCGACGCCGC
AGGCAATTCCTTCGATCCGCAGGAGGGCAAGGCCTGGGAGGCCGGCGCCAAGTGGCAATCGCCCGACCAGCGCCTGAACG
CCTCGATGGCCGTGTTCGACATCCGCAAGACCAACGTGCTCACGCGCGACCCCGCCAACGGCAATTTCAGCGTGGCGGCG
GGCGAAGTGCGCAGCCGCGGCATCGAGACCGACGTGGCGGGCAAGCTGGACGCGCACTGGCGCCTGACGGCCAATGCCGC
CTTCACCGACACCGAGGTGCTGCGCGACAACAATCCTGCCCTCGTGGGCAAGCGCCTGCTGGGCGTCCCGCGCGTGAGCG
CCGGCCTGTTCGCCATCCGCGAAGACCGCCTGGCCTCGGGCGGACGCTACGGCGTGGGCGCGGGCCTGGTGCACGTGGGC
GAGCGCACCGGCACCGCCACCGACACCTACCGGCTGCCCGCCTACACCACGGCACGCCTCACGGGCTACTGGCAGATCGA
CCCGCGCACCCGGCTCACGCTGGACATCCACAACCTGTTCGACAAGCACTACGCCGCCGCCTCGTGGAACGCGATCGCGG
TCATCCCGGGCATGGGGCGGCAGGTGGTGGCGGGGGTGCAGGTCAAGTTCTGA

Upstream 100 bases:

>100_bases
ACTTCCCGCGCCGGAGCTCCCTCCGGCCCTGCTGCACATGCCCGCTTTCTCGTCGCTTTCCACACCGGCCGCCGTGGCCG
CGGCCAATTCGCGCCCCGCC

Downstream 100 bases:

>100_bases
GCCCCAGGCAGCCTGCAGGGCGGCCGTCCCAGGCGGCGCCGGTGGGGGCCCTGCGCGCGATGCGCGGTAACCTTGCCGGC
GTACGACGCGAACGGAAGGC

Product: TonB-dependent siderophore receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 710; Mature: 709

Protein sequence:

>710_residues
MPRRAPLARAVLALAASLSAQHVAHAQEAATAPAAPTATLQEVRVQDATDGSGYQGAQRQTAATRTDTPLVETPQAVRVV
PRQLLEDLGARRLADTVDFVSGVTRMNDFGGTWDNYAIRGFSNTEGGSLLNGFASGRGYGPQRDAATIERVEFLKGPAAA
LYGSSEPGGTLNVVTKKPQFTAARTAGLQIGTLGMRRATLDLTGPATQNLAYRLNVAAEDGASRTGLVDNRKYVVAPAFA
WTLGADTVLQYEAEIIRIRTPLDRGVVQVNGNALALPADRFLQEPDRGNLHVNGDTHQLTLDHDLGGGWRTRLGGTYRET
EFHGNAVDFGTGQIGLLAANGRTLSRTDSWRTLPSRDVSVQAELEGKFSTGSLRHTVLAGLESWRLYMGQDIRYSAQKYP
IDIYDPVYGTVPRGPLVQGYLQDDRLRATGLFLQDQIDLTPRWKLMAGLRFDRFHEDFVNWMTNARQNQQHSSATPRVGL
SYMVTPDSSVYVSYGRSFRPNAGTDAAGNSFDPQEGKAWEAGAKWQSPDQRLNASMAVFDIRKTNVLTRDPANGNFSVAA
GEVRSRGIETDVAGKLDAHWRLTANAAFTDTEVLRDNNPALVGKRLLGVPRVSAGLFAIREDRLASGGRYGVGAGLVHVG
ERTGTATDTYRLPAYTTARLTGYWQIDPRTRLTLDIHNLFDKHYAAASWNAIAVIPGMGRQVVAGVQVKF

Sequences:

>Translated_710_residues
MPRRAPLARAVLALAASLSAQHVAHAQEAATAPAAPTATLQEVRVQDATDGSGYQGAQRQTAATRTDTPLVETPQAVRVV
PRQLLEDLGARRLADTVDFVSGVTRMNDFGGTWDNYAIRGFSNTEGGSLLNGFASGRGYGPQRDAATIERVEFLKGPAAA
LYGSSEPGGTLNVVTKKPQFTAARTAGLQIGTLGMRRATLDLTGPATQNLAYRLNVAAEDGASRTGLVDNRKYVVAPAFA
WTLGADTVLQYEAEIIRIRTPLDRGVVQVNGNALALPADRFLQEPDRGNLHVNGDTHQLTLDHDLGGGWRTRLGGTYRET
EFHGNAVDFGTGQIGLLAANGRTLSRTDSWRTLPSRDVSVQAELEGKFSTGSLRHTVLAGLESWRLYMGQDIRYSAQKYP
IDIYDPVYGTVPRGPLVQGYLQDDRLRATGLFLQDQIDLTPRWKLMAGLRFDRFHEDFVNWMTNARQNQQHSSATPRVGL
SYMVTPDSSVYVSYGRSFRPNAGTDAAGNSFDPQEGKAWEAGAKWQSPDQRLNASMAVFDIRKTNVLTRDPANGNFSVAA
GEVRSRGIETDVAGKLDAHWRLTANAAFTDTEVLRDNNPALVGKRLLGVPRVSAGLFAIREDRLASGGRYGVGAGLVHVG
ERTGTATDTYRLPAYTTARLTGYWQIDPRTRLTLDIHNLFDKHYAAASWNAIAVIPGMGRQVVAGVQVKF
>Mature_709_residues
PRRAPLARAVLALAASLSAQHVAHAQEAATAPAAPTATLQEVRVQDATDGSGYQGAQRQTAATRTDTPLVETPQAVRVVP
RQLLEDLGARRLADTVDFVSGVTRMNDFGGTWDNYAIRGFSNTEGGSLLNGFASGRGYGPQRDAATIERVEFLKGPAAAL
YGSSEPGGTLNVVTKKPQFTAARTAGLQIGTLGMRRATLDLTGPATQNLAYRLNVAAEDGASRTGLVDNRKYVVAPAFAW
TLGADTVLQYEAEIIRIRTPLDRGVVQVNGNALALPADRFLQEPDRGNLHVNGDTHQLTLDHDLGGGWRTRLGGTYRETE
FHGNAVDFGTGQIGLLAANGRTLSRTDSWRTLPSRDVSVQAELEGKFSTGSLRHTVLAGLESWRLYMGQDIRYSAQKYPI
DIYDPVYGTVPRGPLVQGYLQDDRLRATGLFLQDQIDLTPRWKLMAGLRFDRFHEDFVNWMTNARQNQQHSSATPRVGLS
YMVTPDSSVYVSYGRSFRPNAGTDAAGNSFDPQEGKAWEAGAKWQSPDQRLNASMAVFDIRKTNVLTRDPANGNFSVAAG
EVRSRGIETDVAGKLDAHWRLTANAAFTDTEVLRDNNPALVGKRLLGVPRVSAGLFAIREDRLASGGRYGVGAGLVHVGE
RTGTATDTYRLPAYTTARLTGYWQIDPRTRLTLDIHNLFDKHYAAASWNAIAVIPGMGRQVVAGVQVKF

Specific function: Ferrioxamine binding and uptake, in association with the tonB protein. May play a role in intestinal colonization [H]

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1786344, Length=757, Percent_Identity=27.2126816380449, Blast_Score=207, Evalue=2e-54,
Organism=Escherichia coli, GI1787024, Length=709, Percent_Identity=24.9647390691114, Blast_Score=146, Evalue=5e-36,
Organism=Escherichia coli, GI1787344, Length=717, Percent_Identity=23.7099023709902, Blast_Score=107, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 77093; Mature: 76962

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: PS01156 TONB_DEPENDENT_REC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRRAPLARAVLALAASLSAQHVAHAQEAATAPAAPTATLQEVRVQDATDGSGYQGAQRQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHEEECCCCCCCCCCCCHH
TAATRTDTPLVETPQAVRVVPRQLLEDLGARRLADTVDFVSGVTRMNDFGGTWDNYAIRG
HCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
FSNTEGGSLLNGFASGRGYGPQRDAATIERVEFLKGPAAALYGSSEPGGTLNVVTKKPQF
CCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCEEECCCCCCCEEEEEECCCCC
TAARTAGLQIGTLGMRRATLDLTGPATQNLAYRLNVAAEDGASRTGLVDNRKYVVAPAFA
CHHHHCCEEEECCCCEEEEEEECCCCCCCEEEEEEEEECCCCCCCCCCCCCEEEEEEEEE
WTLGADTVLQYEAEIIRIRTPLDRGVVQVNGNALALPADRFLQEPDRGNLHVNGDTHQLT
EECCCCCEEEEEEEEEEEECCCCCCEEEECCCEEEECHHHHHCCCCCCCEEECCCEEEEE
LDHDLGGGWRTRLGGTYRETEFHGNAVDFGTGQIGLLAANGRTLSRTDSWRTLPSRDVSV
EECCCCCCHHHHCCCCEEECCCCCCEEECCCCCEEEEEECCCEECCCCCCCCCCCCCCEE
QAELEGKFSTGSLRHTVLAGLESWRLYMGQDIRYSAQKYPIDIYDPVYGTVPRGPLVQGY
EEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCEECCCCCCEEEECCCCCCCCCCCCEECC
LQDDRLRATGLFLQDQIDLTPRWKLMAGLRFDRFHEDFVNWMTNARQNQQHSSATPRVGL
CCCCCEEEEEEEEEECCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCE
SYMVTPDSSVYVSYGRSFRPNAGTDAAGNSFDPQEGKAWEAGAKWQSPDQRLNASMAVFD
EEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCEEEEEE
IRKTNVLTRDPANGNFSVAAGEVRSRGIETDVAGKLDAHWRLTANAAFTDTEVLRDNNPA
EECCCEEEECCCCCCEEEEECHHHHCCCCCCCCCCCCCEEEEEECCCCCCHHHHCCCCCH
LVGKRLLGVPRVSAGLFAIREDRLASGGRYGVGAGLVHVGERTGTATDTYRLPAYTTARL
HHHHHHHCCCCCCCCEEEEEHHHHCCCCCCCCCCCEEEECCCCCCCCCEEECCCEEEEEE
TGYWQIDPRTRLTLDIHNLFDKHYAAASWNAIAVIPGMGRQVVAGVQVKF
EEEEEECCCCEEEEEHHHHHHHHHHCCCCCEEEEECCCCCEEEEEEEEEC
>Mature Secondary Structure 
PRRAPLARAVLALAASLSAQHVAHAQEAATAPAAPTATLQEVRVQDATDGSGYQGAQRQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHEEECCCCCCCCCCCCHH
TAATRTDTPLVETPQAVRVVPRQLLEDLGARRLADTVDFVSGVTRMNDFGGTWDNYAIRG
HCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
FSNTEGGSLLNGFASGRGYGPQRDAATIERVEFLKGPAAALYGSSEPGGTLNVVTKKPQF
CCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCEEECCCCCCCEEEEEECCCCC
TAARTAGLQIGTLGMRRATLDLTGPATQNLAYRLNVAAEDGASRTGLVDNRKYVVAPAFA
CHHHHCCEEEECCCCEEEEEEECCCCCCCEEEEEEEEECCCCCCCCCCCCCEEEEEEEEE
WTLGADTVLQYEAEIIRIRTPLDRGVVQVNGNALALPADRFLQEPDRGNLHVNGDTHQLT
EECCCCCEEEEEEEEEEEECCCCCCEEEECCCEEEECHHHHHCCCCCCCEEECCCEEEEE
LDHDLGGGWRTRLGGTYRETEFHGNAVDFGTGQIGLLAANGRTLSRTDSWRTLPSRDVSV
EECCCCCCHHHHCCCCEEECCCCCCEEECCCCCEEEEEECCCEECCCCCCCCCCCCCCEE
QAELEGKFSTGSLRHTVLAGLESWRLYMGQDIRYSAQKYPIDIYDPVYGTVPRGPLVQGY
EEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCEECCCCCCEEEECCCCCCCCCCCCEECC
LQDDRLRATGLFLQDQIDLTPRWKLMAGLRFDRFHEDFVNWMTNARQNQQHSSATPRVGL
CCCCCEEEEEEEEEECCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCE
SYMVTPDSSVYVSYGRSFRPNAGTDAAGNSFDPQEGKAWEAGAKWQSPDQRLNASMAVFD
EEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCEEEEEE
IRKTNVLTRDPANGNFSVAAGEVRSRGIETDVAGKLDAHWRLTANAAFTDTEVLRDNNPA
EECCCEEEECCCCCCEEEEECHHHHCCCCCCCCCCCCCEEEEEECCCCCCHHHHCCCCCH
LVGKRLLGVPRVSAGLFAIREDRLASGGRYGVGAGLVHVGERTGTATDTYRLPAYTTARL
HHHHHHHCCCCCCCCEEEEEHHHHCCCCCCCCCCCEEEECCCCCCCCCEEECCCEEEEEE
TGYWQIDPRTRLTLDIHNLFDKHYAAASWNAIAVIPGMGRQVVAGVQVKF
EEEEEECCCCEEEEEHHHHHHHHHHCCCCCEEEEECCCCCEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677609; 10103258; 7642488 [H]