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The map label for this gene is hmrR2 [H]

Identifier: 120608745

GI number: 120608745

Start: 35531

End: 35935

Strand: Reverse

Name: hmrR2 [H]

Synonym: Aave_0032

Alternate gene names: 120608745

Gene position: 35935-35531 (Counterclockwise)

Preceding gene: 120608746

Following gene: 120608744

Centisome position: 0.67

GC content: 72.35

Gene sequence:

>405_bases
GTGGTCGATCCCGTGCCCATCGGCACGGCCGCCGCGCGGGCGGGCGTCTCGCAGCGCATGGTCCGCCACTACGAGGCCCT
CGGCCTGCTGCGGGACGTGGCGCGCACGGACAGCGGCTACCGCCAGTACACCGAGAGGGATGTCCACACCCTGCGCTTCA
TCCGCCGCGCGCGCGACCTGGGCTTCTCCATGGAAGAGATCGCCACCCTGCTCGGGCTCTGGCAGGACCAGCGCCGCGCC
AGCCGCGAGGTCAAGCGCATCGCCCAGGCCCACATCGACGACCTGGGCCGCCGCATCGCCGCCATGCAGGCCATGCAGCG
CTCGCTGCAGCAGCTGGTGGGCTGCTGCCAGGGGGACGGGCGGCCGGACTGTCCGATCCTGGATGATCTGGCGGGCGTGA
ACTGA

Upstream 100 bases:

>100_bases
GAGGGCTACACCGTCGCTGCATGAGCGCGGTACCGAAACGACGCCGCGCCCGGCCCGCAGGCCCGCCGTCCGGCATGGCA
CAGGCCCCCCAGCCACGACG

Downstream 100 bases:

>100_bases
ACGCCGTGCGTCACCCTCGCGGCAGGACCGGGCCGTGCAATGCGATATACCTGACGCCATCACCCGCAGGGGCCCGGACG
TGCATCACGGCCCCTTGTTC

Product: MerR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 134; Mature: 134

Protein sequence:

>134_residues
MVDPVPIGTAAARAGVSQRMVRHYEALGLLRDVARTDSGYRQYTERDVHTLRFIRRARDLGFSMEEIATLLGLWQDQRRA
SREVKRIAQAHIDDLGRRIAAMQAMQRSLQQLVGCCQGDGRPDCPILDDLAGVN

Sequences:

>Translated_134_residues
MVDPVPIGTAAARAGVSQRMVRHYEALGLLRDVARTDSGYRQYTERDVHTLRFIRRARDLGFSMEEIATLLGLWQDQRRA
SREVKRIAQAHIDDLGRRIAAMQAMQRSLQQLVGCCQGDGRPDCPILDDLAGVN
>Mature_134_residues
MVDPVPIGTAAARAGVSQRMVRHYEALGLLRDVARTDSGYRQYTERDVHTLRFIRRARDLGFSMEEIATLLGLWQDQRRA
SREVKRIAQAHIDDLGRRIAAMQAMQRSLQQLVGCCQGDGRPDCPILDDLAGVN

Specific function: Transcriptional regulator involved in acid tolerance. Binds copper [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786695, Length=126, Percent_Identity=35.7142857142857, Blast_Score=97, Evalue=5e-22,
Organism=Escherichia coli, GI1789687, Length=127, Percent_Identity=40.9448818897638, Blast_Score=89, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011789
- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 15061; Mature: 15061

Theoretical pI: Translated: 8.90; Mature: 8.90

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDPVPIGTAAARAGVSQRMVRHYEALGLLRDVARTDSGYRQYTERDVHTLRFIRRARDL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHC
GFSMEEIATLLGLWQDQRRASREVKRIAQAHIDDLGRRIAAMQAMQRSLQQLVGCCQGDG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
RPDCPILDDLAGVN
CCCCCHHHHHCCCC
>Mature Secondary Structure
MVDPVPIGTAAARAGVSQRMVRHYEALGLLRDVARTDSGYRQYTERDVHTLRFIRRARDL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHC
GFSMEEIATLLGLWQDQRRASREVKRIAQAHIDDLGRRIAAMQAMQRSLQQLVGCCQGDG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
RPDCPILDDLAGVN
CCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481431 [H]