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The map label for this gene is chvG [H]

Identifier: 120599092

GI number: 120599092

Start: 2635426

End: 2637585

Strand: Direct

Name: chvG [H]

Synonym: Sputw3181_2288

Alternate gene names: 120599092

Gene position: 2635426-2637585 (Clockwise)

Preceding gene: 120599091

Following gene: 120599093

Centisome position: 55.97

GC content: 47.82

Gene sequence:

>2160_bases
ATGACACGTTTTCCCTTCGGCTTACGCACAAAAGTCATTGGCCTTAGCCTATTTTTACTCTGCCTACCTTGGCTTGGGTA
TCAATATGTTTGGGAGATGGAAAAGTACTTACGCCATGGTCAAGAACGTACTTTAGAAGGAACCACACAGGCGCTTGCAA
CTGCGCTGCACGAGCGCCCAAAGCTGTTTGATGGCCAAGCGAGCTTTTTAAAGCAAGTGGAAAAAAGTCGCGATCTCTAC
GCCTATCCACTGGCGGGAGCAATATTACTCGATGGAAAACTTAACGAGTGGCAGGAATATCAGCACAGATTTATCCAATA
CGGAGAGGCGAATCAAATCATGCGCGCCGATCCAACCACGCCCTTAACCTTAAGTTTTACCCATATGGTCGGCCAATATG
ATGGTTACCTGTACGCCTTTTTCCAAGTAGTTGACCCTAATGTGGTGTTTCGCGGCAAAAATGCCCTCAGTGTCGATAGA
AATGATCACTTATCCATCGCCACATTGTCACCCGACAATAAATTCAAACGCTATATTGTTGCCACCACTCAGCCAGGCTG
GATCAGCGCCTTCGAATTACCCGCTAATCCTAAGCTGACGGTGCCTGTCACCCCGGAAGTGCGTATCCAAGGACAATGGG
CAACAACCGATGTGGGCTACAATATTGAGCTGCGTATTCCCCTTAATATGGTCGGTAGCAAACTCGGCTTTGCCATTGCC
GATGTGAATGACAGTAAATATCGCGACATCACCGCAATTGTGGGTACATCCGCCTTGGACACCGTCGATAAACTCGGCAC
TGTATTAGTTCCATCACCAGAAATTGAAAGTATTATCAAAGGGATGAGTCACTATAGCTCAAGAGTATGGGTGGTAGACA
AACATGGGCGGGTATTAGCGAAATCCGGAGATCTGCGCGCGAATAGCAGTGTCTGGACCCGCACCTTAGAAGATGAAACA
CCAGGCTCACTCTGGGGAAGCTTTAAACGGGATTATCTGCATCCCCTGTATTACAAAATTCTGACAAAACCACCCAAGGA
TTTTATTGATTCGCTGCAGGATTCTACTGAACTTGATGGCAGCCATATCCAAAAAGCGCTCTCGGGTCAGCAAAGTTCGA
CTTGGCGCTTAACCCCAGATAACAAAGCGGTAGTACTCGCCGCTGCGAGCCCTATCTGGATTGATAACAATGTGATGGGC
GCCGTCGTTGCCGAAGAAACCACCCACGGTATTCGTACTCTACGTAACCGTGCCTTGGAAAAACTCTTTAACGTGATCTT
GACCATTATGAGCATGGGCACACTGGCGCTGTTCTTCTTTGCTTCGAGTATTTCAAACCGAATTCGCAAACTGCGGGATG
AGGCAGAAAATGCCATCGACAGCCAAGGTCGAGTGCGCAATAACCTTAAACCGTCAAAGGCTCGGGATGAAATTGGCGAT
CTTTCGCGTAGTTTTTCGAGTATCGTCGGACGCCTAGGCCAATACACCCATTATTTGGAAAATATGTCGTCGCGCCTCTC
CCACGAACTCCGTACCCCCGTCGCCGTAGTGCGATCGTCCCTTGAGCATTTAAACCTGCAAACCTTAGATCAAGATGCGC
AAAAATATGTCGACCGCGCGCAGGAAGGCGTGAGCCGCTTAAGCATGATGCTCAATAATATGAGCGAAGCAACGCGCCTA
GAGCAAAGTTTATTGCAGGCTGATATCACTAAGTTTCCACTGTCTCAAGTGATCAGCGGTTGTATGCAGGGGTATCAAAT
CACTTATCCTGAACAACGATTTAGCGTAAAAGTGCCAGAACAGCCGCTGATGATGCAAGGCGTACCCGAATATATCGCTC
AGTTAATGGATAAGCTTATCGCCAACGCGATTGAGTTTTGTCACAAGGATAGCGCCATTGAAGTGACGCTCACCCAAGTA
GGTAAACAAGCCACATTACTGATCAGTAACTTAGGGCCTGAACTCCCAATTGATATGTCGGAGCAGATTTTCGATTCTAT
GGTGTCAGTGCGGATAAATCAGGCTCAAGATAAACCGCACCTCGGCTTAGGCTTATATATTGCGCGGCTAGTCGCTGAGT
TCCATCAAGGCAAAATTCTCGCCCGTAACCGTAGCGAACACGATGGTGTGGATATCCTAGTCACACTGCCATTAAATTAA

Upstream 100 bases:

>100_bases
CTGCTCCTGAATTTGATTGTATCGATACGGTTTATGGCATGGGCTACCGCTGGGACAGCCTAGCCTAAGTAATGATGGGA
TCTGCTTTGATGTATAACCT

Downstream 100 bases:

>100_bases
CAAATTAAGTAGGTCCTTGGTCAAAGTGAGGCTTCCTTTAGAGCAGAACCTATCGACAAATGGCACAGGAGCGAAGAACA
TGAGCCAAACTCATCACTTC

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: Histidine kinase sensory protein ExoS [H]

Number of amino acids: Translated: 719; Mature: 718

Protein sequence:

>719_residues
MTRFPFGLRTKVIGLSLFLLCLPWLGYQYVWEMEKYLRHGQERTLEGTTQALATALHERPKLFDGQASFLKQVEKSRDLY
AYPLAGAILLDGKLNEWQEYQHRFIQYGEANQIMRADPTTPLTLSFTHMVGQYDGYLYAFFQVVDPNVVFRGKNALSVDR
NDHLSIATLSPDNKFKRYIVATTQPGWISAFELPANPKLTVPVTPEVRIQGQWATTDVGYNIELRIPLNMVGSKLGFAIA
DVNDSKYRDITAIVGTSALDTVDKLGTVLVPSPEIESIIKGMSHYSSRVWVVDKHGRVLAKSGDLRANSSVWTRTLEDET
PGSLWGSFKRDYLHPLYYKILTKPPKDFIDSLQDSTELDGSHIQKALSGQQSSTWRLTPDNKAVVLAAASPIWIDNNVMG
AVVAEETTHGIRTLRNRALEKLFNVILTIMSMGTLALFFFASSISNRIRKLRDEAENAIDSQGRVRNNLKPSKARDEIGD
LSRSFSSIVGRLGQYTHYLENMSSRLSHELRTPVAVVRSSLEHLNLQTLDQDAQKYVDRAQEGVSRLSMMLNNMSEATRL
EQSLLQADITKFPLSQVISGCMQGYQITYPEQRFSVKVPEQPLMMQGVPEYIAQLMDKLIANAIEFCHKDSAIEVTLTQV
GKQATLLISNLGPELPIDMSEQIFDSMVSVRINQAQDKPHLGLGLYIARLVAEFHQGKILARNRSEHDGVDILVTLPLN

Sequences:

>Translated_719_residues
MTRFPFGLRTKVIGLSLFLLCLPWLGYQYVWEMEKYLRHGQERTLEGTTQALATALHERPKLFDGQASFLKQVEKSRDLY
AYPLAGAILLDGKLNEWQEYQHRFIQYGEANQIMRADPTTPLTLSFTHMVGQYDGYLYAFFQVVDPNVVFRGKNALSVDR
NDHLSIATLSPDNKFKRYIVATTQPGWISAFELPANPKLTVPVTPEVRIQGQWATTDVGYNIELRIPLNMVGSKLGFAIA
DVNDSKYRDITAIVGTSALDTVDKLGTVLVPSPEIESIIKGMSHYSSRVWVVDKHGRVLAKSGDLRANSSVWTRTLEDET
PGSLWGSFKRDYLHPLYYKILTKPPKDFIDSLQDSTELDGSHIQKALSGQQSSTWRLTPDNKAVVLAAASPIWIDNNVMG
AVVAEETTHGIRTLRNRALEKLFNVILTIMSMGTLALFFFASSISNRIRKLRDEAENAIDSQGRVRNNLKPSKARDEIGD
LSRSFSSIVGRLGQYTHYLENMSSRLSHELRTPVAVVRSSLEHLNLQTLDQDAQKYVDRAQEGVSRLSMMLNNMSEATRL
EQSLLQADITKFPLSQVISGCMQGYQITYPEQRFSVKVPEQPLMMQGVPEYIAQLMDKLIANAIEFCHKDSAIEVTLTQV
GKQATLLISNLGPELPIDMSEQIFDSMVSVRINQAQDKPHLGLGLYIARLVAEFHQGKILARNRSEHDGVDILVTLPLN
>Mature_718_residues
TRFPFGLRTKVIGLSLFLLCLPWLGYQYVWEMEKYLRHGQERTLEGTTQALATALHERPKLFDGQASFLKQVEKSRDLYA
YPLAGAILLDGKLNEWQEYQHRFIQYGEANQIMRADPTTPLTLSFTHMVGQYDGYLYAFFQVVDPNVVFRGKNALSVDRN
DHLSIATLSPDNKFKRYIVATTQPGWISAFELPANPKLTVPVTPEVRIQGQWATTDVGYNIELRIPLNMVGSKLGFAIAD
VNDSKYRDITAIVGTSALDTVDKLGTVLVPSPEIESIIKGMSHYSSRVWVVDKHGRVLAKSGDLRANSSVWTRTLEDETP
GSLWGSFKRDYLHPLYYKILTKPPKDFIDSLQDSTELDGSHIQKALSGQQSSTWRLTPDNKAVVLAAASPIWIDNNVMGA
VVAEETTHGIRTLRNRALEKLFNVILTIMSMGTLALFFFASSISNRIRKLRDEAENAIDSQGRVRNNLKPSKARDEIGDL
SRSFSSIVGRLGQYTHYLENMSSRLSHELRTPVAVVRSSLEHLNLQTLDQDAQKYVDRAQEGVSRLSMMLNNMSEATRLE
QSLLQADITKFPLSQVISGCMQGYQITYPEQRFSVKVPEQPLMMQGVPEYIAQLMDKLIANAIEFCHKDSAIEVTLTQVG
KQATLLISNLGPELPIDMSEQIFDSMVSVRINQAQDKPHLGLGLYIARLVAEFHQGKILARNRSEHDGVDILVTLPLN

Specific function: Member of a two-component regulatory system ChvG(ExoS)/ChvI involved in regulating the production of succinoglycan. Activates ChvI by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=248, Percent_Identity=23.3870967741935, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1786912, Length=217, Percent_Identity=26.7281105990783, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1790346, Length=275, Percent_Identity=24.7272727272727, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 80825; Mature: 80693

Theoretical pI: Translated: 7.32; Mature: 7.32

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRFPFGLRTKVIGLSLFLLCLPWLGYQYVWEMEKYLRHGQERTLEGTTQALATALHERP
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCHHHHHHHHHHHHHHCC
KLFDGQASFLKQVEKSRDLYAYPLAGAILLDGKLNEWQEYQHRFIQYGEANQIMRADPTT
CCCCCHHHHHHHHHHCCCEEEECCCCEEEECCCCCHHHHHHHHHHHCCCCCCEEECCCCC
PLTLSFTHMVGQYDGYLYAFFQVVDPNVVFRGKNALSVDRNDHLSIATLSPDNKFKRYIV
CEEEEHHHHHHCCCCCEEEEEEEECCCEEEECCCEEECCCCCCEEEEEECCCCCCEEEEE
ATTQPGWISAFELPANPKLTVPVTPEVRIQGQWATTDVGYNIELRIPLNMVGSKLGFAIA
EECCCCCEEEEECCCCCEEEEECCCCEEEECEEEEECCCEEEEEEECHHHHHHHHCEEEE
DVNDSKYRDITAIVGTSALDTVDKLGTVLVPSPEIESIIKGMSHYSSRVWVVDKHGRVLA
CCCCCCHHHHHHHHCCHHHHHHHHCCEEECCCCCHHHHHHHHHHHCCEEEEEECCCEEEE
KSGDLRANSSVWTRTLEDETPGSLWGSFKRDYLHPLYYKILTKPPKDFIDSLQDSTELDG
ECCCCCCCCHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCH
SHIQKALSGQQSSTWRLTPDNKAVVLAAASPIWIDNNVMGAVVAEETTHGIRTLRNRALE
HHHHHHHCCCCCCEEEECCCCCEEEEEECCCEEECCCCEEEEEEHHHHHHHHHHHHHHHH
KLFNVILTIMSMGTLALFFFASSISNRIRKLRDEAENAIDSQGRVRNNLKPSKARDEIGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCHHHHHHHH
LSRSFSSIVGRLGQYTHYLENMSSRLSHELRTPVAVVRSSLEHLNLQTLDQDAQKYVDRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCHHHHHHHHHHHHHHH
QEGVSRLSMMLNNMSEATRLEQSLLQADITKFPLSQVISGCMQGYQITYPEQRFSVKVPE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCEEECCCCCCEEECCC
QPLMMQGVPEYIAQLMDKLIANAIEFCHKDSAIEVTLTQVGKQATLLISNLGPELPIDMS
CCHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHCCCHHEEEEECCCCCCCCCCH
EQIFDSMVSVRINQAQDKPHLGLGLYIARLVAEFHQGKILARNRSEHDGVDILVTLPLN
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCEEEECCCCCCCCCEEEEEECCC
>Mature Secondary Structure 
TRFPFGLRTKVIGLSLFLLCLPWLGYQYVWEMEKYLRHGQERTLEGTTQALATALHERP
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCHHHHHHHHHHHHHHCC
KLFDGQASFLKQVEKSRDLYAYPLAGAILLDGKLNEWQEYQHRFIQYGEANQIMRADPTT
CCCCCHHHHHHHHHHCCCEEEECCCCEEEECCCCCHHHHHHHHHHHCCCCCCEEECCCCC
PLTLSFTHMVGQYDGYLYAFFQVVDPNVVFRGKNALSVDRNDHLSIATLSPDNKFKRYIV
CEEEEHHHHHHCCCCCEEEEEEEECCCEEEECCCEEECCCCCCEEEEEECCCCCCEEEEE
ATTQPGWISAFELPANPKLTVPVTPEVRIQGQWATTDVGYNIELRIPLNMVGSKLGFAIA
EECCCCCEEEEECCCCCEEEEECCCCEEEECEEEEECCCEEEEEEECHHHHHHHHCEEEE
DVNDSKYRDITAIVGTSALDTVDKLGTVLVPSPEIESIIKGMSHYSSRVWVVDKHGRVLA
CCCCCCHHHHHHHHCCHHHHHHHHCCEEECCCCCHHHHHHHHHHHCCEEEEEECCCEEEE
KSGDLRANSSVWTRTLEDETPGSLWGSFKRDYLHPLYYKILTKPPKDFIDSLQDSTELDG
ECCCCCCCCHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCH
SHIQKALSGQQSSTWRLTPDNKAVVLAAASPIWIDNNVMGAVVAEETTHGIRTLRNRALE
HHHHHHHCCCCCCEEEECCCCCEEEEEECCCEEECCCCEEEEEEHHHHHHHHHHHHHHHH
KLFNVILTIMSMGTLALFFFASSISNRIRKLRDEAENAIDSQGRVRNNLKPSKARDEIGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCHHHHHHHH
LSRSFSSIVGRLGQYTHYLENMSSRLSHELRTPVAVVRSSLEHLNLQTLDQDAQKYVDRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCHHHHHHHHHHHHHHH
QEGVSRLSMMLNNMSEATRLEQSLLQADITKFPLSQVISGCMQGYQITYPEQRFSVKVPE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCEEECCCCCCEEECCC
QPLMMQGVPEYIAQLMDKLIANAIEFCHKDSAIEVTLTQVGKQATLLISNLGPELPIDMS
CCHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHCCCHHEEEEECCCCCCCCCCH
EQIFDSMVSVRINQAQDKPHLGLGLYIARLVAEFHQGKILARNRSEHDGVDILVTLPLN
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCEEEECCCCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9422587; 11481430; 7559334 [H]