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The map label for this gene is hypB [H]

Identifier: 120598981

GI number: 120598981

Start: 2506642

End: 2507424

Strand: Direct

Name: hypB [H]

Synonym: Sputw3181_2173

Alternate gene names: 120598981

Gene position: 2506642-2507424 (Clockwise)

Preceding gene: 120598980

Following gene: 120598982

Centisome position: 53.24

GC content: 46.1

Gene sequence:

>783_bases
ATGTGTAAAGACTGCGGCTGCTCTCTTACCCGCCACGAACATGATCATCTCGGCGCGCATTCACATAACCACGAGCACCA
CCATCCTGAACTGCACACGAATCCCCAGTTAAACGATAAAAAAACCTTATCGGTTATTCACAAAATTCTCGACAAAAATG
ATGTTGAAGCGGGCCATAATCGTGCTCATTTCGAGGCGCATAATATTACCGCCTTTAATTTGATGAGCAGTCCTGGCAGT
GGTAAAACCACGCTTTTAGAAAACCTCAAAGAATACACCACGCTTAACTATGCGGTGATTGAAGGCGATTTAGAAACCTC
GCGCGATGCTGATCGTCTCATCGCGAAAGGTATTAAAGCCTACCAAATTCAAACCGGATCGGCTTGTCACCTTGATGCCT
TCATGGTTCACGGCGCCCTGCACCACTTACCCCTTGAAGGCTTAGATATTTGTTTTGTGGAAAACGTCGGCAACCTCGTT
TGTCCTGCAAGCTATGATGTGGGCACCCATAAAAATATCGTGCTGCTATCCGTACCAGAGGGCGATGATAAGATTGAAAA
ATATCCGGTAATGTTCCGCCGCGCCGATGTCGTTTTTATCACTAAGTGCGATCTGCTGCCCTATTTTGATTTCAATCTAG
CCGAAGCCAGAGCCCAGCTAAAAAAACTCAATCCAGATACCCAAATCATTGAAGTCTCAATTAAAGATGGCGACTCAATG
CAGGCCGTTGCCCAGTGGCTTAAGGACAATATTCGCCAAACATCTGTGGGAGAGTCGCAATAA

Upstream 100 bases:

>100_bases
ACATTAGCGTAACCAAATTTAACGATTTGCCCATAATATTATGGTGACGGGGTAAGCTAAATCCAAGGGTCATCATAATG
CCTAAAGGAGTGATAACACT

Downstream 100 bases:

>100_bases
TGTGCTTATCCATTCCTTCCCAAGTCGTGGCCATTGATGCCGAGCGCCAGAGTGTCACCGTCGACACCTTAGGGGTTCGC
CGCGATGTCAGTAGTCATTT

Product: hydrogenase accessory protein HypB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MCKDCGCSLTRHEHDHLGAHSHNHEHHHPELHTNPQLNDKKTLSVIHKILDKNDVEAGHNRAHFEAHNITAFNLMSSPGS
GKTTLLENLKEYTTLNYAVIEGDLETSRDADRLIAKGIKAYQIQTGSACHLDAFMVHGALHHLPLEGLDICFVENVGNLV
CPASYDVGTHKNIVLLSVPEGDDKIEKYPVMFRRADVVFITKCDLLPYFDFNLAEARAQLKKLNPDTQIIEVSIKDGDSM
QAVAQWLKDNIRQTSVGESQ

Sequences:

>Translated_260_residues
MCKDCGCSLTRHEHDHLGAHSHNHEHHHPELHTNPQLNDKKTLSVIHKILDKNDVEAGHNRAHFEAHNITAFNLMSSPGS
GKTTLLENLKEYTTLNYAVIEGDLETSRDADRLIAKGIKAYQIQTGSACHLDAFMVHGALHHLPLEGLDICFVENVGNLV
CPASYDVGTHKNIVLLSVPEGDDKIEKYPVMFRRADVVFITKCDLLPYFDFNLAEARAQLKKLNPDTQIIEVSIKDGDSM
QAVAQWLKDNIRQTSVGESQ
>Mature_260_residues
MCKDCGCSLTRHEHDHLGAHSHNHEHHHPELHTNPQLNDKKTLSVIHKILDKNDVEAGHNRAHFEAHNITAFNLMSSPGS
GKTTLLENLKEYTTLNYAVIEGDLETSRDADRLIAKGIKAYQIQTGSACHLDAFMVHGALHHLPLEGLDICFVENVGNLV
CPASYDVGTHKNIVLLSVPEGDDKIEKYPVMFRRADVVFITKCDLLPYFDFNLAEARAQLKKLNPDTQIIEVSIKDGDSM
QAVAQWLKDNIRQTSVGESQ

Specific function: Plays a role in both the hydrogenase and the urease nickel cofactor insertion step [H]

COG id: COG0378

COG function: function code OK; Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypB/hupM family [H]

Homologues:

Organism=Escherichia coli, GI1789082, Length=216, Percent_Identity=44.9074074074074, Blast_Score=187, Evalue=5e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR004392
- InterPro:   IPR012202 [H]

Pfam domain/function: PF02492 cobW [H]

EC number: NA

Molecular weight: Translated: 29059; Mature: 29059

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCKDCGCSLTRHEHDHLGAHSHNHEHHHPELHTNPQLNDKKTLSVIHKILDKNDVEAGHN
CCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCC
RAHFEAHNITAFNLMSSPGSGKTTLLENLKEYTTLNYAVIEGDLETSRDADRLIAKGIKA
CCEEEECCEEEEEEECCCCCCHHHHHHHHHHHHEEEEEEEECCCCCCCHHHHHHHCCCEE
YQIQTGSACHLDAFMVHGALHHLPLEGLDICFVENVGNLVCPASYDVGTHKNIVLLSVPE
EEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCEECCCCCCCCCCCCEEEEECCC
GDDKIEKYPVMFRRADVVFITKCDLLPYFDFNLAEARAQLKKLNPDTQIIEVSIKDGDSM
CCCHHHHCCCEEEECCEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCH
QAVAQWLKDNIRQTSVGESQ
HHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MCKDCGCSLTRHEHDHLGAHSHNHEHHHPELHTNPQLNDKKTLSVIHKILDKNDVEAGHN
CCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCC
RAHFEAHNITAFNLMSSPGSGKTTLLENLKEYTTLNYAVIEGDLETSRDADRLIAKGIKA
CCEEEECCEEEEEEECCCCCCHHHHHHHHHHHHEEEEEEEECCCCCCCHHHHHHHCCCEE
YQIQTGSACHLDAFMVHGALHHLPLEGLDICFVENVGNLVCPASYDVGTHKNIVLLSVPE
EEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCEECCCCCCCCCCCCEEEEECCC
GDDKIEKYPVMFRRADVVFITKCDLLPYFDFNLAEARAQLKKLNPDTQIIEVSIKDGDSM
CCCHHHHCCCEEEECCEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCH
QAVAQWLKDNIRQTSVGESQ
HHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682; 11123699 [H]