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The map label for this gene is insF1 [H]

Identifier: 120598848

GI number: 120598848

Start: 2349978

End: 2350727

Strand: Direct

Name: insF1 [H]

Synonym: Sputw3181_2038

Alternate gene names: 120598848

Gene position: 2349978-2350727 (Clockwise)

Preceding gene: 120598846

Following gene: 120598849

Centisome position: 49.91

GC content: 50.93

Gene sequence:

>750_bases
ATGAAGCGTGCCGAGCGTGCCGAGCGTGATGCGCTGATAAAGGAAGCGTTTGACGACGCCAAAGCTCGTAACGGCTCCAG
GCGCATTCAGGTTGACCTTGCTGAGCATGGCAAGAAACCGGATGTAAAAACCATACTGAACAGCATGGAGCGCCAGGGTT
TAGTGGCTAAAGCGGCCCGCAAGTTTAAAGTGACGACCGACAGCAAGCATTCGCTGCAAGTCGCCCCAAACTTGCTTGAG
CAGGACTTTAGCGCAACAGGCCCGAACCAGAAATGGGTCGGTGATATCACGTACCTGATGACCAGCGAAGGCTGGCTGTA
TCTGGCGGTAATCATTGATCTGTACTCGCGGGCAGTAATTGGCTGGTCGATGAGCAACCGTATGACAGCAGATCTGGTAT
GCAGCGCATTGAACATGGCGTTGTTCCGTCGCGGCTTCCCAAAATCGGTGATCGTTCATAGTGATCGAGGCAGCCAGTAC
TGCTCGCATGATTACCGTGACTTGATTAAAAAGCACCAATTAGTGCAAAGCATGAGCCGCAAAGGAAACTGCTGGGACGT
CAACGCCTGTGCGGAAAGCTTCTTCCACTCATTGAAAGTTGAAGCAATCCAGGACGAGCCGATAATGGATCGGGAAACCA
TGCGCCAACACGTTTTTGAATACATTGAGGTTGATTACGACAAGACCAGAAGGCATAGTGCTCTTAGCTATCTCAGCCCA
GAGAATTTTGAATTGAAGAACAGTGCTTAG

Upstream 100 bases:

>100_bases
ATATTCATACATTTTCTCTGCATTAAGCTAATTTTGAATTATAAGTGGCAGGTTAACGTAACTAGCAAGTAAAAGCGGCC
TGACACCGCGCCCAAGGGCT

Downstream 100 bases:

>100_bases
TGAAACAAAACCGGTAACCACCGAACGCGACACAAAGCGCATTAAATCGCCCAGCTTAAACAAACCAATTTTGTATTGTA
GCATTAGCAGGCAAAAATTA

Product: integrase catalytic subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MKRAERAERDALIKEAFDDAKARNGSRRIQVDLAEHGKKPDVKTILNSMERQGLVAKAARKFKVTTDSKHSLQVAPNLLE
QDFSATGPNQKWVGDITYLMTSEGWLYLAVIIDLYSRAVIGWSMSNRMTADLVCSALNMALFRRGFPKSVIVHSDRGSQY
CSHDYRDLIKKHQLVQSMSRKGNCWDVNACAESFFHSLKVEAIQDEPIMDRETMRQHVFEYIEVDYDKTRRHSALSYLSP
ENFELKNSA

Sequences:

>Translated_249_residues
MKRAERAERDALIKEAFDDAKARNGSRRIQVDLAEHGKKPDVKTILNSMERQGLVAKAARKFKVTTDSKHSLQVAPNLLE
QDFSATGPNQKWVGDITYLMTSEGWLYLAVIIDLYSRAVIGWSMSNRMTADLVCSALNMALFRRGFPKSVIVHSDRGSQY
CSHDYRDLIKKHQLVQSMSRKGNCWDVNACAESFFHSLKVEAIQDEPIMDRETMRQHVFEYIEVDYDKTRRHSALSYLSP
ENFELKNSA
>Mature_249_residues
MKRAERAERDALIKEAFDDAKARNGSRRIQVDLAEHGKKPDVKTILNSMERQGLVAKAARKFKVTTDSKHSLQVAPNLLE
QDFSATGPNQKWVGDITYLMTSEGWLYLAVIIDLYSRAVIGWSMSNRMTADLVCSALNMALFRRGFPKSVIVHSDRGSQY
CSHDYRDLIKKHQLVQSMSRKGNCWDVNACAESFFHSLKVEAIQDEPIMDRETMRQHVFEYIEVDYDKTRRHSALSYLSP
ENFELKNSA

Specific function: Involved in the transposition of the insertion sequence IS3 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=192, Percent_Identity=38.5416666666667, Blast_Score=135, Evalue=2e-32,
Organism=Escherichia coli, GI1788405, Length=244, Percent_Identity=59.4262295081967, Blast_Score=290, Evalue=5e-80,
Organism=Escherichia coli, GI1787263, Length=244, Percent_Identity=59.4262295081967, Blast_Score=290, Evalue=5e-80,
Organism=Escherichia coli, GI1786753, Length=244, Percent_Identity=59.4262295081967, Blast_Score=290, Evalue=5e-80,
Organism=Escherichia coli, GI1786570, Length=244, Percent_Identity=59.4262295081967, Blast_Score=290, Evalue=5e-80,
Organism=Escherichia coli, GI1786490, Length=244, Percent_Identity=59.4262295081967, Blast_Score=290, Evalue=5e-80,
Organism=Escherichia coli, GI1789981, Length=229, Percent_Identity=36.6812227074236, Blast_Score=136, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 28539; Mature: 28539

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRAERAERDALIKEAFDDAKARNGSRRIQVDLAEHGKKPDVKTILNSMERQGLVAKAAR
CCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHCCCCCCHHHHHHHHHHCCHHHHHHH
KFKVTTDSKHSLQVAPNLLEQDFSATGPNQKWVGDITYLMTSEGWLYLAVIIDLYSRAVI
HEECCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHEEEEEECCCHHHHHHHHHHHHHHHH
GWSMSNRMTADLVCSALNMALFRRGFPKSVIVHSDRGSQYCSHDYRDLIKKHQLVQSMSR
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHC
KGNCWDVNACAESFFHSLKVEAIQDEPIMDRETMRQHVFEYIEVDYDKTRRHSALSYLSP
CCCCEEHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
ENFELKNSA
CCCCCCCCC
>Mature Secondary Structure
MKRAERAERDALIKEAFDDAKARNGSRRIQVDLAEHGKKPDVKTILNSMERQGLVAKAAR
CCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHCCCCCCHHHHHHHHHHCCHHHHHHH
KFKVTTDSKHSLQVAPNLLEQDFSATGPNQKWVGDITYLMTSEGWLYLAVIIDLYSRAVI
HEECCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHEEEEEECCCHHHHHHHHHHHHHHHH
GWSMSNRMTADLVCSALNMALFRRGFPKSVIVHSDRGSQYCSHDYRDLIKKHQLVQSMSR
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHC
KGNCWDVNACAESFFHSLKVEAIQDEPIMDRETMRQHVFEYIEVDYDKTRRHSALSYLSP
CCCCEEHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
ENFELKNSA
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2987844; 9278503 [H]