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The map label for this gene is yeiG [H]

Identifier: 120598652

GI number: 120598652

Start: 2117173

End: 2118015

Strand: Direct

Name: yeiG [H]

Synonym: Sputw3181_1836

Alternate gene names: 120598652

Gene position: 2117173-2118015 (Clockwise)

Preceding gene: 120598651

Following gene: 120598654

Centisome position: 44.97

GC content: 49.23

Gene sequence:

>843_bases
ATGACCATAGAAAATATCAGTTGTAACAAGAGTTTCGGCGGTTGGCATAAGCAGTATCGCCATCAATCTCAGGCGCTAAA
TTGCGAGATGCGCTTTGCGATTTATCTGCCGCCAGAGGCAGTCATTAAGCCAGTGCCTGTGCTGTATTGGCTCTCGGGCC
TAACCTGCACCGATGAAAACTTTATGCAGAAGGCGGGCGCCCAGCGCATGGCGGCCGAGCTTGGGATGGCGATAGTTGCC
CCCGATACCAGTCCTCGTGGTGATGATGTGCCCGATGCGGCGGATAAAGCCTACGACTTAGGCTTAGGCGCGGGTTTTTA
CCTCAATGCAACCAAGGCACCCTGGAATCGTCATTACAAAATGTACGATTACATAGTCCATGAGCTGCCAACTTTGATTG
AAGCGCATTTCCCTGTCACTACTCAGCGCGCTATCTCCGGCCATTCGATGGGCGGTCATGGTGCTTTGGTGATTGGGTTG
AGTAACCCGCACAGATACAGCTCAATTTCGGCTTTTAGCCCGATTTCGAATCCGAGTAATGCACCTTGGGGTATTAAAGC
CTTTAGCGAGTACTTAGGTGAAAATCGTGAACATTGGCGCCAGTATGATGCCTGTGAGTTGCTTAAGCTCGCGATTAGCG
AAGTGCCAGTACTAATTGACCAAGGTGAAGCTGACAGCTTTTTAGACACCCAATTGATGCCACAATCGCTGGTGGATATC
GCCCATGCCAAGGGTTATCCCTTAGATATGCGGATGCAGCCAGGTTACGATCATAGCTATTACTTTATAGCGAGCTTTAT
TGAAGAGCACCTTAAGTTCCATAGCTTGTACTTTAAGCCATAA

Upstream 100 bases:

>100_bases
GTTTGCTGTGTTGCCAACTGAGCAGACGATCAGCGCCATGACGAATGCTAAGATAAATGCTAAGACAAAACGCTAAAAGA
TTGAGCTTAAAAGGACTTGT

Downstream 100 bases:

>100_bases
ATAGCCGATTCGGTAGTCACGTCGATGCGCTAAAACAAAAATGCCGCAACTCACTGAGTTGCGGCATTTTTCATGGTGCG
ATTTAAGCGATTAACGAGAG

Product: carboxylesterase

Products: NA

Alternate protein names: FGH [H]

Number of amino acids: Translated: 280; Mature: 279

Protein sequence:

>280_residues
MTIENISCNKSFGGWHKQYRHQSQALNCEMRFAIYLPPEAVIKPVPVLYWLSGLTCTDENFMQKAGAQRMAAELGMAIVA
PDTSPRGDDVPDAADKAYDLGLGAGFYLNATKAPWNRHYKMYDYIVHELPTLIEAHFPVTTQRAISGHSMGGHGALVIGL
SNPHRYSSISAFSPISNPSNAPWGIKAFSEYLGENREHWRQYDACELLKLAISEVPVLIDQGEADSFLDTQLMPQSLVDI
AHAKGYPLDMRMQPGYDHSYYFIASFIEEHLKFHSLYFKP

Sequences:

>Translated_280_residues
MTIENISCNKSFGGWHKQYRHQSQALNCEMRFAIYLPPEAVIKPVPVLYWLSGLTCTDENFMQKAGAQRMAAELGMAIVA
PDTSPRGDDVPDAADKAYDLGLGAGFYLNATKAPWNRHYKMYDYIVHELPTLIEAHFPVTTQRAISGHSMGGHGALVIGL
SNPHRYSSISAFSPISNPSNAPWGIKAFSEYLGENREHWRQYDACELLKLAISEVPVLIDQGEADSFLDTQLMPQSLVDI
AHAKGYPLDMRMQPGYDHSYYFIASFIEEHLKFHSLYFKP
>Mature_279_residues
TIENISCNKSFGGWHKQYRHQSQALNCEMRFAIYLPPEAVIKPVPVLYWLSGLTCTDENFMQKAGAQRMAAELGMAIVAP
DTSPRGDDVPDAADKAYDLGLGAGFYLNATKAPWNRHYKMYDYIVHELPTLIEAHFPVTTQRAISGHSMGGHGALVIGLS
NPHRYSSISAFSPISNPSNAPWGIKAFSEYLGENREHWRQYDACELLKLAISEVPVLIDQGEADSFLDTQLMPQSLVDIA
HAKGYPLDMRMQPGYDHSYYFIASFIEEHLKFHSLYFKP

Specific function: Serine hydrolase involved in the detoxification of formaldehyde. Hydrolyzes S-formylglutathione to glutathione and formate [H]

COG id: COG0627

COG function: function code R; Predicted esterase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the esterase D family [H]

Homologues:

Organism=Homo sapiens, GI33413400, Length=281, Percent_Identity=51.9572953736655, Blast_Score=311, Evalue=6e-85,
Organism=Escherichia coli, GI1788477, Length=278, Percent_Identity=57.5539568345324, Blast_Score=338, Evalue=2e-94,
Organism=Escherichia coli, GI1786551, Length=273, Percent_Identity=54.2124542124542, Blast_Score=312, Evalue=1e-86,
Organism=Caenorhabditis elegans, GI17510185, Length=279, Percent_Identity=47.3118279569892, Blast_Score=253, Evalue=6e-68,
Organism=Saccharomyces cerevisiae, GI6322393, Length=283, Percent_Identity=42.756183745583, Blast_Score=224, Evalue=1e-59,
Organism=Drosophila melanogaster, GI45551932, Length=280, Percent_Identity=48.5714285714286, Blast_Score=278, Evalue=3e-75,
Organism=Drosophila melanogaster, GI24648347, Length=280, Percent_Identity=48.5714285714286, Blast_Score=278, Evalue=4e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000801
- InterPro:   IPR014186 [H]

Pfam domain/function: PF00756 Esterase [H]

EC number: =3.1.2.12 [H]

Molecular weight: Translated: 31464; Mature: 31333

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIENISCNKSFGGWHKQYRHQSQALNCEMRFAIYLPPEAVIKPVPVLYWLSGLTCTDEN
CCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEEEEECHHHHHCCCCHHHHHCCCCCCCHH
FMQKAGAQRMAAELGMAIVAPDTSPRGDDVPDAADKAYDLGLGAGFYLNATKAPWNRHYK
HHHHHHHHHHHHHHCEEEECCCCCCCCCCCCCHHHHHHHCCCCCCEEEECCCCCHHHHHH
MYDYIVHELPTLIEAHFPVTTQRAISGHSMGGHGALVIGLSNPHRYSSISAFSPISNPSN
HHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCC
APWGIKAFSEYLGENREHWRQYDACELLKLAISEVPVLIDQGEADSFLDTQLMPQSLVDI
CCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHH
AHAKGYPLDMRMQPGYDHSYYFIASFIEEHLKFHSLYFKP
HHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TIENISCNKSFGGWHKQYRHQSQALNCEMRFAIYLPPEAVIKPVPVLYWLSGLTCTDEN
CCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEEEEECHHHHHCCCCHHHHHCCCCCCCHH
FMQKAGAQRMAAELGMAIVAPDTSPRGDDVPDAADKAYDLGLGAGFYLNATKAPWNRHYK
HHHHHHHHHHHHHHCEEEECCCCCCCCCCCCCHHHHHHHCCCCCCEEEECCCCCHHHHHH
MYDYIVHELPTLIEAHFPVTTQRAISGHSMGGHGALVIGLSNPHRYSSISAFSPISNPSN
HHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCC
APWGIKAFSEYLGENREHWRQYDACELLKLAISEVPVLIDQGEADSFLDTQLMPQSLVDI
CCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHH
AHAKGYPLDMRMQPGYDHSYYFIASFIEEHLKFHSLYFKP
HHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA