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The map label for this gene is prc [H]

Identifier: 120598623

GI number: 120598623

Start: 2077674

End: 2079719

Strand: Direct

Name: prc [H]

Synonym: Sputw3181_1807

Alternate gene names: 120598623

Gene position: 2077674-2079719 (Clockwise)

Preceding gene: 120598622

Following gene: 120598624

Centisome position: 44.13

GC content: 41.84

Gene sequence:

>2046_bases
ATGCGAAAACTCACTTTGGCTATCTCGATTGCCACTGTTTTTGTCGGATTTTCGGCTTGGGCCGTACCACCCACGATTCA
AATCAGCGAGTTACCCACTCTCAAGCAAGAGGCACAACATAAGGTTGCCAGTAAGAGAGTGACGGACTTATATACTCGTT
CGCATTACCACAGATTCAACTTAGATGATGCGTTTTCAGCGCAAATCTTCGATCGCTATCTACAACAATTGGATTATCGC
CGCAATGTATTGACCCAAGCGGATGTAGATAGCTTTAAACCTTATATTAATCAATTCGATAACATGTTGATTTCCGGTGA
GCTTGAACCTGCATACAAGATGTTTGATGTAGTGCAAAAGCGCCGTTATGAAGGCTTTGTTTATGCCTTGTCATTATTGG
ATCAAGAAATTGATTTTACAGTTCCGGCTGATGTGTACGAATACGATAGGGAAGATGCTGCTTGGCCTAAGGATCAAGCT
GAGATCAATGAACTGTGGCGTCAACGTGTTAAATATGATGCGTTAAATCTTAAGTTAACAGGCAAAAAGTGGCCTGAGAT
CGTCGATATTTTACAAAAGCGCTATAACAACGCGATCAAACGTCTCACTCAAACAAACAGTGAAGATGTATTTCAAGGTG
TGATGAATGCTTTTTCCCGTAGCATAGAGCCACATACTAGCTACCTATCGCCACGCAATGCTGAGCGTTTCCAAATGGAA
ATGAACCTTAGTCTTGAAGGTATTGGTGCTCAATTGCAGCTTGAAGATGATTACACAGTGATCAAGAGTTTGATTGCGGG
CGGGCCTGCTGCTGGTAGCGAGAAGCTTTCACCCGAAGATAAAATTGTTGGTGTTGGTCAGGAGGGCGGCGAGATTGTCG
ATGTCATTGGTTGGCGTTTAGACGATGTTGTTGACCTTATAAAAGGGCCAAAAGGCAGTAAAGTGGTTCTGCAAATTCTA
CCTAAGAAGGGTGGCTCAAATGCAAAACCATTCAATTTGACCTTAGTACGTGACAAGATTCGCCTCGAAGATCGCGCGGC
AACATCAAAAGTGATTGAACCTAAAGAAGGTGAATACGCCAATCGTAAAGTGGGTGTTATTCAAATCCCTGGTTTCTACA
TGAATTTGTCGCAAGACGTTGAAAAAGAACTCGTTAAACTTAACGAAGCTAAAGTAGAAGGGATTGTTATCGACTTAAGA
GGAAACGGTGGTGGAGCGTTAACTGAGGCCGTATTGCTGACAGGACTCTTTATTAATATGGGGCCTGTCGTACAAATTCG
GGATGCCGATGGCCGAGTGTCAGCACACCGTGATAATGATGGTAAAACCAGCTATTCAGGCCCATTAACTGTGATGGTTG
ATCGTTATAGCGCCTCTGCATCTGAGATTTTCGCCGCTGCATTACAGGACTATGACCGAGCATTAATTGTGGGTGAATCA
AGTTTTGGTAAGGGCACGGTACAGCAACATAAGAGTTTAGGCCGTATTTACGATATGTATGATAAGCCTATTGGTCATGT
GCAGTACACTATTCAAAAATTTTATCGTATTAATGGTGGCAGCACCCAAATTAAAGGGGTCACTCCTAATATTGCTTATC
CAAGTGCATTAGAGCCAGGTGAGTATGGTGAAGCTGAAGAGAAAAATGCATTGCCATGGGATAAAGTTCCGGAAGCCCAA
TACAATAGATTAAGTGATGTAACGCCTGAGTTGGTTGTTAACTTAGAGAAGAAACACCTCAACCGAATTAAAGACAGCGT
AGAGTTTAATTATATCAATCAAGATATTGCTGAATTTAAAAAGCATCACAAAGAGAAGACCATTTCTTTAGTTGAGAGTG
AACGAATTGCTTCTCGTGAAGCTGATGAGAAAAAATTGTTAGATAGAACCAATGAACGCCGTGTTGCTCAAGGTTTGGCT
GTGGTTAAATCCATGGAAGACATTAAAGATACTACTGAAGCACCGGATCCATTTTTAGACGAAACCGCTTATATCACCTT
AGATATGATTGATGCTAAAAAGCTCGCTAAAACTAATGTGCAATAG

Upstream 100 bases:

>100_bases
AAAGAGGACATTCATGTTCAGCTTGATAGCGGTCTAACGATTAAAGTTAGAGCGGAACATATCCTGCTGTAATCATTTAT
TAAGACGGAGTAACTTGTTG

Downstream 100 bases:

>100_bases
GTGTGACTAAAGAGATATACCCCGTATTAAAACGCGCTTATGGCGCGTTTTTCTTATTAAGCTCAGAGTTAAAGGGATCG
AAATGACGCAAGCACAAGCC

Product: carboxy-terminal protease

Products: NA

Alternate protein names: C-terminal-processing peptidase; PRC protein; Protease Re [H]

Number of amino acids: Translated: 681; Mature: 681

Protein sequence:

>681_residues
MRKLTLAISIATVFVGFSAWAVPPTIQISELPTLKQEAQHKVASKRVTDLYTRSHYHRFNLDDAFSAQIFDRYLQQLDYR
RNVLTQADVDSFKPYINQFDNMLISGELEPAYKMFDVVQKRRYEGFVYALSLLDQEIDFTVPADVYEYDREDAAWPKDQA
EINELWRQRVKYDALNLKLTGKKWPEIVDILQKRYNNAIKRLTQTNSEDVFQGVMNAFSRSIEPHTSYLSPRNAERFQME
MNLSLEGIGAQLQLEDDYTVIKSLIAGGPAAGSEKLSPEDKIVGVGQEGGEIVDVIGWRLDDVVDLIKGPKGSKVVLQIL
PKKGGSNAKPFNLTLVRDKIRLEDRAATSKVIEPKEGEYANRKVGVIQIPGFYMNLSQDVEKELVKLNEAKVEGIVIDLR
GNGGGALTEAVLLTGLFINMGPVVQIRDADGRVSAHRDNDGKTSYSGPLTVMVDRYSASASEIFAAALQDYDRALIVGES
SFGKGTVQQHKSLGRIYDMYDKPIGHVQYTIQKFYRINGGSTQIKGVTPNIAYPSALEPGEYGEAEEKNALPWDKVPEAQ
YNRLSDVTPELVVNLEKKHLNRIKDSVEFNYINQDIAEFKKHHKEKTISLVESERIASREADEKKLLDRTNERRVAQGLA
VVKSMEDIKDTTEAPDPFLDETAYITLDMIDAKKLAKTNVQ

Sequences:

>Translated_681_residues
MRKLTLAISIATVFVGFSAWAVPPTIQISELPTLKQEAQHKVASKRVTDLYTRSHYHRFNLDDAFSAQIFDRYLQQLDYR
RNVLTQADVDSFKPYINQFDNMLISGELEPAYKMFDVVQKRRYEGFVYALSLLDQEIDFTVPADVYEYDREDAAWPKDQA
EINELWRQRVKYDALNLKLTGKKWPEIVDILQKRYNNAIKRLTQTNSEDVFQGVMNAFSRSIEPHTSYLSPRNAERFQME
MNLSLEGIGAQLQLEDDYTVIKSLIAGGPAAGSEKLSPEDKIVGVGQEGGEIVDVIGWRLDDVVDLIKGPKGSKVVLQIL
PKKGGSNAKPFNLTLVRDKIRLEDRAATSKVIEPKEGEYANRKVGVIQIPGFYMNLSQDVEKELVKLNEAKVEGIVIDLR
GNGGGALTEAVLLTGLFINMGPVVQIRDADGRVSAHRDNDGKTSYSGPLTVMVDRYSASASEIFAAALQDYDRALIVGES
SFGKGTVQQHKSLGRIYDMYDKPIGHVQYTIQKFYRINGGSTQIKGVTPNIAYPSALEPGEYGEAEEKNALPWDKVPEAQ
YNRLSDVTPELVVNLEKKHLNRIKDSVEFNYINQDIAEFKKHHKEKTISLVESERIASREADEKKLLDRTNERRVAQGLA
VVKSMEDIKDTTEAPDPFLDETAYITLDMIDAKKLAKTNVQ
>Mature_681_residues
MRKLTLAISIATVFVGFSAWAVPPTIQISELPTLKQEAQHKVASKRVTDLYTRSHYHRFNLDDAFSAQIFDRYLQQLDYR
RNVLTQADVDSFKPYINQFDNMLISGELEPAYKMFDVVQKRRYEGFVYALSLLDQEIDFTVPADVYEYDREDAAWPKDQA
EINELWRQRVKYDALNLKLTGKKWPEIVDILQKRYNNAIKRLTQTNSEDVFQGVMNAFSRSIEPHTSYLSPRNAERFQME
MNLSLEGIGAQLQLEDDYTVIKSLIAGGPAAGSEKLSPEDKIVGVGQEGGEIVDVIGWRLDDVVDLIKGPKGSKVVLQIL
PKKGGSNAKPFNLTLVRDKIRLEDRAATSKVIEPKEGEYANRKVGVIQIPGFYMNLSQDVEKELVKLNEAKVEGIVIDLR
GNGGGALTEAVLLTGLFINMGPVVQIRDADGRVSAHRDNDGKTSYSGPLTVMVDRYSASASEIFAAALQDYDRALIVGES
SFGKGTVQQHKSLGRIYDMYDKPIGHVQYTIQKFYRINGGSTQIKGVTPNIAYPSALEPGEYGEAEEKNALPWDKVPEAQ
YNRLSDVTPELVVNLEKKHLNRIKDSVEFNYINQDIAEFKKHHKEKTISLVESERIASREADEKKLLDRTNERRVAQGLA
VVKSMEDIKDTTEAPDPFLDETAYITLDMIDAKKLAKTNVQ

Specific function: Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 (PBP3). May be involved in protection of the bacterium from thermal and osmotic stresses [H]

COG id: COG0793

COG function: function code M; Periplasmic protease

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Periplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1788134, Length=663, Percent_Identity=53.393665158371, Blast_Score=670, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR005151
- InterPro:   IPR004447
- InterPro:   IPR020992 [H]

Pfam domain/function: PF11818 DUF3340; PF00595 PDZ; PF03572 Peptidase_S41 [H]

EC number: =3.4.21.102 [H]

Molecular weight: Translated: 76745; Mature: 76745

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKLTLAISIATVFVGFSAWAVPPTIQISELPTLKQEAQHKVASKRVTDLYTRSHYHRFN
CCEEEEEHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCEECC
LDDAFSAQIFDRYLQQLDYRRNVLTQADVDSFKPYINQFDNMLISGELEPAYKMFDVVQK
CCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHH
RRYEGFVYALSLLDQEIDFTVPADVYEYDREDAAWPKDQAEINELWRQRVKYDALNLKLT
HHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCEEEEEEC
GKKWPEIVDILQKRYNNAIKRLTQTNSEDVFQGVMNAFSRSIEPHTSYLSPRNAERFQME
CCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCEEEE
MNLSLEGIGAQLQLEDDYTVIKSLIAGGPAAGSEKLSPEDKIVGVGQEGGEIVDVIGWRL
ECCEEECCCCEEEECCCHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCCCHHHHHCCH
DDVVDLIKGPKGSKVVLQILPKKGGSNAKPFNLTLVRDKIRLEDRAATSKVIEPKEGEYA
HHHHHHHCCCCCCEEEEEEECCCCCCCCCCEEEEEEECHHHHHHHHHHHHCCCCCCCCCC
NRKVGVIQIPGFYMNLSQDVEKELVKLNEAKVEGIVIDLRGNGGGALTEAVLLTGLFINM
CCEEEEEECCCCEECCHHHHHHHHHHHCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHCC
GPVVQIRDADGRVSAHRDNDGKTSYSGPLTVMVDRYSASASEIFAAALQDYDRALIVGES
CCEEEEECCCCCEEECCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCEEEEECC
SFGKGTVQQHKSLGRIYDMYDKPIGHVQYTIQKFYRINGGSTQIKGVTPNIAYPSALEPG
CCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEECCCCEEEEECCCCCCCCCCCCCC
EYGEAEEKNALPWDKVPEAQYNRLSDVTPELVVNLEKKHLNRIKDSVEFNYINQDIAEFK
CCCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHCCHHHHHHHHHHHHEEEHHHHHHHHHH
KHHKEKTISLVESERIASREADEKKLLDRTNERRVAQGLAVVKSMEDIKDTTEAPDPFLD
HHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
ETAYITLDMIDAKKLAKTNVQ
CCEEEEEEECCHHHHHHCCCC
>Mature Secondary Structure
MRKLTLAISIATVFVGFSAWAVPPTIQISELPTLKQEAQHKVASKRVTDLYTRSHYHRFN
CCEEEEEHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCEECC
LDDAFSAQIFDRYLQQLDYRRNVLTQADVDSFKPYINQFDNMLISGELEPAYKMFDVVQK
CCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHH
RRYEGFVYALSLLDQEIDFTVPADVYEYDREDAAWPKDQAEINELWRQRVKYDALNLKLT
HHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCEEEEEEC
GKKWPEIVDILQKRYNNAIKRLTQTNSEDVFQGVMNAFSRSIEPHTSYLSPRNAERFQME
CCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCEEEE
MNLSLEGIGAQLQLEDDYTVIKSLIAGGPAAGSEKLSPEDKIVGVGQEGGEIVDVIGWRL
ECCEEECCCCEEEECCCHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCCCHHHHHCCH
DDVVDLIKGPKGSKVVLQILPKKGGSNAKPFNLTLVRDKIRLEDRAATSKVIEPKEGEYA
HHHHHHHCCCCCCEEEEEEECCCCCCCCCCEEEEEEECHHHHHHHHHHHHCCCCCCCCCC
NRKVGVIQIPGFYMNLSQDVEKELVKLNEAKVEGIVIDLRGNGGGALTEAVLLTGLFINM
CCEEEEEECCCCEECCHHHHHHHHHHHCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHCC
GPVVQIRDADGRVSAHRDNDGKTSYSGPLTVMVDRYSASASEIFAAALQDYDRALIVGES
CCEEEEECCCCCEEECCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCEEEEECC
SFGKGTVQQHKSLGRIYDMYDKPIGHVQYTIQKFYRINGGSTQIKGVTPNIAYPSALEPG
CCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEECCCCEEEEECCCCCCCCCCCCCC
EYGEAEEKNALPWDKVPEAQYNRLSDVTPELVVNLEKKHLNRIKDSVEFNYINQDIAEFK
CCCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHCCHHHHHHHHHHHHEEEHHHHHHHHHH
KHHKEKTISLVESERIASREADEKKLLDRTNERRVAQGLAVVKSMEDIKDTTEAPDPFLD
HHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
ETAYITLDMIDAKKLAKTNVQ
CCEEEEEEECCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1856173; 1729701; 9097040; 9278503; 1447154; 10049386; 7499412; 8576225 [H]