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The map label for this gene is pabC [H]

Identifier: 120598609

GI number: 120598609

Start: 2063882

End: 2064691

Strand: Direct

Name: pabC [H]

Synonym: Sputw3181_1793

Alternate gene names: 120598609

Gene position: 2063882-2064691 (Clockwise)

Preceding gene: 120598608

Following gene: 120598610

Centisome position: 43.83

GC content: 44.2

Gene sequence:

>810_bases
GTGATTTGGGTGAATGGTGTGTTGCAGGGGAGTATTGATCCTTCCGATCGGGGACTTACTTACGGTGATGGTCTGTTTGC
AACCATGCGAACGAGCCATGACGGTATTTTGTTTTTAAATGCACATCAATCACGCTTAACCGATGGTGCCGCAAGACTCG
GTTTTGAATGGCGCATGGGCAGTGCGCTTTATCAGCAACTTGAGGATTTGGCCAGACAGTATCCCCATCATTGTATTAAA
CTTTTGGTTTCAAGAGGTGTTGGTGGGAGAGGTTATACACCACCACAAGCTGTTAATGTTACTGAAGTCGTCTCTGTGCA
TCCGATTCCTAGCCATTATGCACATTGGCAAAAAAACGGTATCAACCTTAAAACATCCCCTGTTCGCCTAGGTATACAGC
CATTATTGGCAGGGATTAAACACCTTAATCGTCTTGAACAAGTACTGATTAAAGCTCAGCTTTTACCGAGTAACGTCGAT
GATTGGTTAGTCTTAGATACTGAGGCGAAGGTGATTGAATCTTCGATGGCAAATATCTTTTTTATCAAAGACAATGAGGT
TATTACGCCATCTTTAGCCCAATGTGGTGTGTCTGGCGTGATGCGTGAGCAGGTGATTAATGCCTTGCTCGAACAACAGT
TCAATATTCAATGTTTGCCATTTGGCGCCGAGCGTTTAGGGGAGTTTGACTCGGCATTTATCACTAACAGTGTTTTAGGT
GTTGTGGATGTACTGGCGATAGATTCGCTTAAGTTCACTCGATCCCCTATAACCGCCAACCTTAGACAGACACTTTCACT
CACACTATGA

Upstream 100 bases:

>100_bases
TAAGTGGCCCAGTGGCACGTCCCTATAACACCCGTAAAAATGCCAAGTATAAAGATCAACAAGAAGCGGTCGCTAGCCGC
ATAAGTCAGGACTAACATCC

Downstream 100 bases:

>100_bases
AAAAACTGATCCTGATTGCCAGTTCAACTCTACTTACCTTACTGACATTAGTTTGTTTAGTGGGTTACTGGGGTTATCAA
ACTATTGTTGATTATAGTAA

Product: aminotransferase, class IV

Products: NA

Alternate protein names: 4-amino-4-deoxychorismate lyase; ADC lyase; ADCL [H]

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MIWVNGVLQGSIDPSDRGLTYGDGLFATMRTSHDGILFLNAHQSRLTDGAARLGFEWRMGSALYQQLEDLARQYPHHCIK
LLVSRGVGGRGYTPPQAVNVTEVVSVHPIPSHYAHWQKNGINLKTSPVRLGIQPLLAGIKHLNRLEQVLIKAQLLPSNVD
DWLVLDTEAKVIESSMANIFFIKDNEVITPSLAQCGVSGVMREQVINALLEQQFNIQCLPFGAERLGEFDSAFITNSVLG
VVDVLAIDSLKFTRSPITANLRQTLSLTL

Sequences:

>Translated_269_residues
MIWVNGVLQGSIDPSDRGLTYGDGLFATMRTSHDGILFLNAHQSRLTDGAARLGFEWRMGSALYQQLEDLARQYPHHCIK
LLVSRGVGGRGYTPPQAVNVTEVVSVHPIPSHYAHWQKNGINLKTSPVRLGIQPLLAGIKHLNRLEQVLIKAQLLPSNVD
DWLVLDTEAKVIESSMANIFFIKDNEVITPSLAQCGVSGVMREQVINALLEQQFNIQCLPFGAERLGEFDSAFITNSVLG
VVDVLAIDSLKFTRSPITANLRQTLSLTL
>Mature_269_residues
MIWVNGVLQGSIDPSDRGLTYGDGLFATMRTSHDGILFLNAHQSRLTDGAARLGFEWRMGSALYQQLEDLARQYPHHCIK
LLVSRGVGGRGYTPPQAVNVTEVVSVHPIPSHYAHWQKNGINLKTSPVRLGIQPLLAGIKHLNRLEQVLIKAQLLPSNVD
DWLVLDTEAKVIESSMANIFFIKDNEVITPSLAQCGVSGVMREQVINALLEQQFNIQCLPFGAERLGEFDSAFITNSVLG
VVDVLAIDSLKFTRSPITANLRQTLSLTL

Specific function: Converts 4-amino-4-deoxychorismate into 4-aminobenzoate (PABA) and pyruvate [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787338, Length=257, Percent_Identity=39.2996108949416, Blast_Score=181, Evalue=3e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017824
- InterPro:   IPR001544
- InterPro:   IPR018300 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =4.1.3.38 [H]

Molecular weight: Translated: 29667; Mature: 29667

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: PS00770 AA_TRANSFER_CLASS_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIWVNGVLQGSIDPSDRGLTYGDGLFATMRTSHDGILFLNAHQSRLTDGAARLGFEWRMG
CEEECEEEECCCCCCCCCCEECCCEEEEEECCCCCEEEEECCHHHHHHHHHHCCCCCHHH
SALYQQLEDLARQYPHHCIKLLVSRGVGGRGYTPPQAVNVTEVVSVHPIPSHYAHWQKNG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHEEEECCCCHHHHHHHCCC
INLKTSPVRLGIQPLLAGIKHLNRLEQVLIKAQLLPSNVDDWLVLDTEAKVIESSMANIF
CCEECCCHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHCCCEEE
FIKDNEVITPSLAQCGVSGVMREQVINALLEQQFNIQCLPFGAERLGEFDSAFITNSVLG
EEECCCEECCHHHHHCHHHHHHHHHHHHHHHCCCCEEEEECCHHHHCCHHHHHHHHHHHH
VVDVLAIDSLKFTRSPITANLRQTLSLTL
HHHHHHHCCCHHCCCCCHHHHHHHHEECC
>Mature Secondary Structure
MIWVNGVLQGSIDPSDRGLTYGDGLFATMRTSHDGILFLNAHQSRLTDGAARLGFEWRMG
CEEECEEEECCCCCCCCCCEECCCEEEEEECCCCCEEEEECCHHHHHHHHHHCCCCCHHH
SALYQQLEDLARQYPHHCIKLLVSRGVGGRGYTPPQAVNVTEVVSVHPIPSHYAHWQKNG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHEEEECCCCHHHHHHHCCC
INLKTSPVRLGIQPLLAGIKHLNRLEQVLIKAQLLPSNVDDWLVLDTEAKVIESSMANIF
CCEECCCHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHCCCEEE
FIKDNEVITPSLAQCGVSGVMREQVINALLEQQFNIQCLPFGAERLGEFDSAFITNSVLG
EEECCCEECCHHHHHCHHHHHHHHHHHHHHHCCCCEEEEECCHHHHCCHHHHHHHHHHHH
VVDVLAIDSLKFTRSPITANLRQTLSLTL
HHHHHHHCCCHHCCCCCHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1644759; 8905232; 9278503; 2071583; 2251281; 10876155 [H]