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The map label for this gene is corA [H]

Identifier: 120598566

GI number: 120598566

Start: 2012136

End: 2013083

Strand: Direct

Name: corA [H]

Synonym: Sputw3181_1749

Alternate gene names: 120598566

Gene position: 2012136-2013083 (Clockwise)

Preceding gene: 120598565

Following gene: 120598568

Centisome position: 42.74

GC content: 41.14

Gene sequence:

>948_bases
ATGATTACTGCTTATATCTACGAAAATCGTCACCTCACCGTGGCAGAAATCAGTATACAAGACAGTATTCCCACGTCGAC
CATTTGGTTAGATCTTTATAAACCTGATGATGCAGAGCGAGAATGGTTAAGTCATTTTTCCGTTGAAGAAGTCCCTGATG
AAGAAGATATTAATGAGATTGAGGCGTCGGCGCGTTTTTATCAAAATAGCGATGGGCTTCATATCAACTCTCTGTTTCCA
CAACGTGTAGGCCAAGACGTCCGCGGTGTAAACGTCTCATTTAATTTACGCAGCAATTTTTTGCTGACTATCCGTGAAGA
AGATGTAGGACTTATCCGCTTATTACGTAACTACCTACGTTTAGGTCGACTTGAGGTTTCTACTCCACAGGAGTTGTTCC
TCGAGCTTTTTAATCTCAAAGTGGACTACCTTTCAGATTTAATTGAAGACGTATATACCGTATTGGAAAATGTCGGTGAG
CAAGTATTTGATAACGATCAACTTGATAGCGTGTTCAAACTGATCACCTTGCAAGAAGACTCCAATGGAAAAATTCGTCT
AAGTTTGCTCGATACTCAGCGTTCACTGCGTTATATGCAGCGTTACTACCGTGGACAATTGTCCGATGAGCATCTTAAAG
ATCTGCGGGAAATGTTGTCAGATATCGAGTCACTGATGCCCCATAGCCAGTTTATTTTCGATAAATTAAACTTTTTGCTT
GATGCGGCGATGGGTTTTAGTGGATTACAACAAAATAAAATCATCAAAATATTCTCGGTTGCGGCAGTGGTATTCCTGCC
TCCGACGCTCATTGCCAGTAGCTATGGAATGAACTTTAGCAGTATGCCGGAGCTTGAGTGGCAGTATGGTTATCCAATGG
CAATAGTAATGATGTTAGCTAGTGCGGCAGGCACTTACTTTTTCTTTAAACGTAAACACTGGTTATAA

Upstream 100 bases:

>100_bases
TATGCATCTTTTCATTGCTAACTTATGCGGTAAACTAGCGACAATTTTTTAGCCTGCACTTAAGTGGCCTTTTCGCTTAG
GTTTTGTTTCAGGAGGACAA

Downstream 100 bases:

>100_bases
CACTAGGTCAGATTATTGAGACAAAGCCGAATAGTTAATTCGGCTTTTTTTATGACAGGTTACTTACGGCTATCGCCACC
AAAATAGTAACTGACACGCT

Product: magnesium and cobalt transport protein CorA

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MITAYIYENRHLTVAEISIQDSIPTSTIWLDLYKPDDAEREWLSHFSVEEVPDEEDINEIEASARFYQNSDGLHINSLFP
QRVGQDVRGVNVSFNLRSNFLLTIREEDVGLIRLLRNYLRLGRLEVSTPQELFLELFNLKVDYLSDLIEDVYTVLENVGE
QVFDNDQLDSVFKLITLQEDSNGKIRLSLLDTQRSLRYMQRYYRGQLSDEHLKDLREMLSDIESLMPHSQFIFDKLNFLL
DAAMGFSGLQQNKIIKIFSVAAVVFLPPTLIASSYGMNFSSMPELEWQYGYPMAIVMMLASAAGTYFFFKRKHWL

Sequences:

>Translated_315_residues
MITAYIYENRHLTVAEISIQDSIPTSTIWLDLYKPDDAEREWLSHFSVEEVPDEEDINEIEASARFYQNSDGLHINSLFP
QRVGQDVRGVNVSFNLRSNFLLTIREEDVGLIRLLRNYLRLGRLEVSTPQELFLELFNLKVDYLSDLIEDVYTVLENVGE
QVFDNDQLDSVFKLITLQEDSNGKIRLSLLDTQRSLRYMQRYYRGQLSDEHLKDLREMLSDIESLMPHSQFIFDKLNFLL
DAAMGFSGLQQNKIIKIFSVAAVVFLPPTLIASSYGMNFSSMPELEWQYGYPMAIVMMLASAAGTYFFFKRKHWL
>Mature_315_residues
MITAYIYENRHLTVAEISIQDSIPTSTIWLDLYKPDDAEREWLSHFSVEEVPDEEDINEIEASARFYQNSDGLHINSLFP
QRVGQDVRGVNVSFNLRSNFLLTIREEDVGLIRLLRNYLRLGRLEVSTPQELFLELFNLKVDYLSDLIEDVYTVLENVGE
QVFDNDQLDSVFKLITLQEDSNGKIRLSLLDTQRSLRYMQRYYRGQLSDEHLKDLREMLSDIESLMPHSQFIFDKLNFLL
DAAMGFSGLQQNKIIKIFSVAAVVFLPPTLIASSYGMNFSSMPELEWQYGYPMAIVMMLASAAGTYFFFKRKHWL

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=320, Percent_Identity=42.1875, Blast_Score=253, Evalue=9e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 36633; Mature: 36633

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITAYIYENRHLTVAEISIQDSIPTSTIWLDLYKPDDAEREWLSHFSVEEVPDEEDINEI
CEEEEEEECCEEEEEEEEECCCCCCEEEEEEEECCCCHHHHHHHHCCHHCCCCCCHHHHH
EASARFYQNSDGLHINSLFPQRVGQDVRGVNVSFNLRSNFLLTIREEDVGLIRLLRNYLR
HHHHHHHCCCCCEEEECCCHHHHCCCCCCCEEEEEECCCEEEEEECCCHHHHHHHHHHHH
LGRLEVSTPQELFLELFNLKVDYLSDLIEDVYTVLENVGEQVFDNDQLDSVFKLITLQED
HCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHEEEEC
SNGKIRLSLLDTQRSLRYMQRYYRGQLSDEHLKDLREMLSDIESLMPHSQFIFDKLNFLL
CCCEEEEEEECHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
DAAMGFSGLQQNKIIKIFSVAAVVFLPPTLIASSYGMNFSSMPELEWQYGYPMAIVMMLA
HHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHH
SAAGTYFFFKRKHWL
HHCCCEEEEECCCCC
>Mature Secondary Structure
MITAYIYENRHLTVAEISIQDSIPTSTIWLDLYKPDDAEREWLSHFSVEEVPDEEDINEI
CEEEEEEECCEEEEEEEEECCCCCCEEEEEEEECCCCHHHHHHHHCCHHCCCCCCHHHHH
EASARFYQNSDGLHINSLFPQRVGQDVRGVNVSFNLRSNFLLTIREEDVGLIRLLRNYLR
HHHHHHHCCCCCEEEECCCHHHHCCCCCCCEEEEEECCCEEEEEECCCHHHHHHHHHHHH
LGRLEVSTPQELFLELFNLKVDYLSDLIEDVYTVLENVGEQVFDNDQLDSVFKLITLQED
HCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHEEEEC
SNGKIRLSLLDTQRSLRYMQRYYRGQLSDEHLKDLREMLSDIESLMPHSQFIFDKLNFLL
CCCEEEEEEECHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
DAAMGFSGLQQNKIIKIFSVAAVVFLPPTLIASSYGMNFSSMPELEWQYGYPMAIVMMLA
HHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHH
SAAGTYFFFKRKHWL
HHCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA