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The map label for this gene is bioC [H]

Identifier: 120598482

GI number: 120598482

Start: 1919217

End: 1920026

Strand: Direct

Name: bioC [H]

Synonym: Sputw3181_1665

Alternate gene names: 120598482

Gene position: 1919217-1920026 (Clockwise)

Preceding gene: 120598481

Following gene: 120598483

Centisome position: 40.76

GC content: 45.8

Gene sequence:

>810_bases
ATGAACCAAATCAAGTCGAGTGAGCTTAGCTATGCAGGGGATATCCAAGTTCCGTCGATTGCGGAGCGTTTTTCCGCTGC
CGCCCATCACTATCAAGATCATAACAAGTTACAGCGACTGAGTGCCGCGAGTTTACTGGACGGTTTTATTGCTACTGGCA
ATCTTTTAGATATTGGCGCAGGACCAGGAACTCGGTTTGAATTTCCACAAGCGGCAATCTCTAAGCCGAAGGTTTTTGCG
CTAGATATTGCCTTGGGGATGCTGAAAAAACTGAAGCAGACTTATCCTCATTACCAAAGTATTTGTGCTGATGCCGCGCA
ATTACCTTTGGGTGAGGGTACTATGGATAGCATCTACTCCAATCTTGCATTGCAATGGTGTGCGGATTTTCCGGCTGTGG
TTGCCGAAATGGCGCGGGTGCTAAGGCCAAATGGTGAATGCCATTTGGCGATTGTTGCCGATGGTAGCCTTAATGAATTG
TCAGCATTAGGCCTACGAGTCAATGCTTTTTCTCCTATGGATGAGTTAATCGGTGCTTTTGATTCTGAGAAATGGCAACT
ATCCAAGGTTACATTAGTCCCAATGACAGTACATTTTGACACACTTAAAGCACTGCTTTATTCCATTAAAGGGGTTGGCG
CTTCTGTTCAATCTTACCGTGTTAGCGCATTGCCACATGGTGAAATACTTAAGCTTCGCGGCCGCAAAGATTGGCAGGAT
CTCATCTTACATGCTGAAATGTTGCGCCAACCGCAAGGCTTACCTCTGACTTATCAAATTGCACAAATTCGTGCGCGTCG
ATTAGGTTAA

Upstream 100 bases:

>100_bases
GTCGTTTATGACAAAAGTCCATTATTCATGCTGACTTTGGACTGTACCAATATGAGTATCGTGAGTGAATGCAGATTGTA
AAAACAGAATGTGAGTTGTT

Downstream 100 bases:

>100_bases
CCGAATCGGATAACGGGGTAGTTTAATAAAGGATCTAATATGTTTTTTGTAACAGGAACAGATACCGACAGCGGTAAGAC
CTTGGTTTCATCGGCATTAT

Product: biotin biosynthesis protein BioC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MNQIKSSELSYAGDIQVPSIAERFSAAAHHYQDHNKLQRLSAASLLDGFIATGNLLDIGAGPGTRFEFPQAAISKPKVFA
LDIALGMLKKLKQTYPHYQSICADAAQLPLGEGTMDSIYSNLALQWCADFPAVVAEMARVLRPNGECHLAIVADGSLNEL
SALGLRVNAFSPMDELIGAFDSEKWQLSKVTLVPMTVHFDTLKALLYSIKGVGASVQSYRVSALPHGEILKLRGRKDWQD
LILHAEMLRQPQGLPLTYQIAQIRARRLG

Sequences:

>Translated_269_residues
MNQIKSSELSYAGDIQVPSIAERFSAAAHHYQDHNKLQRLSAASLLDGFIATGNLLDIGAGPGTRFEFPQAAISKPKVFA
LDIALGMLKKLKQTYPHYQSICADAAQLPLGEGTMDSIYSNLALQWCADFPAVVAEMARVLRPNGECHLAIVADGSLNEL
SALGLRVNAFSPMDELIGAFDSEKWQLSKVTLVPMTVHFDTLKALLYSIKGVGASVQSYRVSALPHGEILKLRGRKDWQD
LILHAEMLRQPQGLPLTYQIAQIRARRLG
>Mature_269_residues
MNQIKSSELSYAGDIQVPSIAERFSAAAHHYQDHNKLQRLSAASLLDGFIATGNLLDIGAGPGTRFEFPQAAISKPKVFA
LDIALGMLKKLKQTYPHYQSICADAAQLPLGEGTMDSIYSNLALQWCADFPAVVAEMARVLRPNGECHLAIVADGSLNEL
SALGLRVNAFSPMDELIGAFDSEKWQLSKVTLVPMTVHFDTLKALLYSIKGVGASVQSYRVSALPHGEILKLRGRKDWQD
LILHAEMLRQPQGLPLTYQIAQIRARRLG

Specific function: BioC is involved in an early, but chemically unexplored, step in the conversion of pimelic acid to biotin [H]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily [H]

Homologues:

Organism=Escherichia coli, GI1786994, Length=196, Percent_Identity=33.6734693877551, Blast_Score=91, Evalue=9e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011814
- InterPro:   IPR013216 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: NA

Molecular weight: Translated: 29453; Mature: 29453

Theoretical pI: Translated: 8.10; Mature: 8.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQIKSSELSYAGDIQVPSIAERFSAAAHHYQDHNKLQRLSAASLLDGFIATGNLLDIGA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECC
GPGTRFEFPQAAISKPKVFALDIALGMLKKLKQTYPHYQSICADAAQLPLGEGTMDSIYS
CCCCCCCCCHHHHCCCCEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHH
NLALQWCADFPAVVAEMARVLRPNGECHLAIVADGSLNELSALGLRVNAFSPMDELIGAF
HHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHCEEEECCCCHHHHHHCC
DSEKWQLSKVTLVPMTVHFDTLKALLYSIKGVGASVQSYRVSALPHGEILKLRGRKDWQD
CCCCEEEEEEEEEEEEECHHHHHHHHHHHHCCCCCHHHEEEECCCCCCEEEECCCCCHHH
LILHAEMLRQPQGLPLTYQIAQIRARRLG
HHHHHHHHCCCCCCCEEHHHHHHHHHHCC
>Mature Secondary Structure
MNQIKSSELSYAGDIQVPSIAERFSAAAHHYQDHNKLQRLSAASLLDGFIATGNLLDIGA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECC
GPGTRFEFPQAAISKPKVFALDIALGMLKKLKQTYPHYQSICADAAQLPLGEGTMDSIYS
CCCCCCCCCHHHHCCCCEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHH
NLALQWCADFPAVVAEMARVLRPNGECHLAIVADGSLNELSALGLRVNAFSPMDELIGAF
HHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHCEEEECCCCHHHHHHCC
DSEKWQLSKVTLVPMTVHFDTLKALLYSIKGVGASVQSYRVSALPHGEILKLRGRKDWQD
CCCCEEEEEEEEEEEEECHHHHHHHHHHHHCCCCCHHHEEEECCCCCCEEEECCCCCHHH
LILHAEMLRQPQGLPLTYQIAQIRARRLG
HHHHHHHHCCCCCCCEEHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9063571 [H]