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The map label for this gene is fabH [H]

Identifier: 120598458

GI number: 120598458

Start: 1878348

End: 1879469

Strand: Direct

Name: fabH [H]

Synonym: Sputw3181_1641

Alternate gene names: 120598458

Gene position: 1878348-1879469 (Clockwise)

Preceding gene: 120598457

Following gene: 120598460

Centisome position: 39.89

GC content: 46.35

Gene sequence:

>1122_bases
ATGAAACAGGTCGTTATTTCTGGGAGTGGCTTATTTACGCCGCCCTACAGTATTTCCAATGAAGCTTTGGTTGAAAGCTT
CAATGCCTATGTTGATATTTTCAATCTTGAAAATGCAGGCTTAATTGAACAAGGCCATGTTGCGGCCTTATCCTATTCAT
CAAGTGAGTTTATTGAAAAAGCATCTGGGATTAAGCACAGATATGTGATGGTGAAAGAGGGCATACTCGATCCTGAAATT
ATGATGCCGCTCATTCCTGAACGCAGTAGCGACGAGTTATCAATGCAGGCTGAAATAGGGGTTGAGGCGGCGCTGATGGC
GCTAAACAATGCCAATCTTAAGGCGGAGCAAATTGATCTTGTGATTGTTGCCTGTGCTTATACTCAGCGCGCTTATCCCG
CGATGGCGATTGAAATCCAACGCGCCCTTGGTACGCGGGGTTACGGTTACGATATGCAGGTGGCTTGTTCATCGGCGACC
TTTGCGATTGTTGCGGCTGCTAATGCGATTGCGACAGGTTCTGCCTCAAGAGTGCTAGTGATCAACCCCGAAATTTGCTC
GGCGCAGGTGAATTATCGCGACCGTGATAGCCATTTTATCTTTGGCGATGTGGCGACGGCCCTTGTACTTGAAGAGCAGA
GTTTAGTCGAGCCCAATAAAGGCTTTACGATTCTCTCAAGCCGTTGCTTCACCGATTACTCAAACAATATTCGCAGTAAT
TTTGGCTTTTTAAATCGCTGCGATCCGAGTTCGGCACATCAAGCCGACAAGTTATTCCACCAACAAGGGCGCAAAGTATT
TAAAGAACTCTTGCCGATGATTTATCAGCATTTGGATGAACATCTGGCCGAGCAAGCATTAACGCCACAGTCCTTCAAAC
GGTTGTGGTTGCACCAAGCTAACATCAATATGAACCAATTTGTGGTAAGAAAAATGCTTGGGGATGAGGTATCGCCGGAG
CAAGCGCCAGTGGTGTTAGATGAATATGCCAATACGGCATCGGCAGGTTCTGTGATTGCATTTCATAAATATTCCAGCGA
TTTTAAGGCTGGCGATTTAGGTCTATTAAGCTCCTTTGGTGCGGGTTACTCCATCGGCAGCGTGATCCTGCAAAAACGCT
AA

Upstream 100 bases:

>100_bases
GATTAGAGCAGCAAGCACAGCGTCAAGATGTGATGCCTGTGCTGACGAATGATCCTTCTACGTCTGCTCACCTTACAACA
AGCACCCGTTCGGAGCACCT

Downstream 100 bases:

>100_bases
ATTAATCTAGGAATAAGCAGATTGTTCTACAATTTTTTAATAAAAACAGCCTCATTTGAGGCTGTTTTTATTTTGTAGGG
ATTTGTTGCTTAAACTACTC

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MKQVVISGSGLFTPPYSISNEALVESFNAYVDIFNLENAGLIEQGHVAALSYSSSEFIEKASGIKHRYVMVKEGILDPEI
MMPLIPERSSDELSMQAEIGVEAALMALNNANLKAEQIDLVIVACAYTQRAYPAMAIEIQRALGTRGYGYDMQVACSSAT
FAIVAAANAIATGSASRVLVINPEICSAQVNYRDRDSHFIFGDVATALVLEEQSLVEPNKGFTILSSRCFTDYSNNIRSN
FGFLNRCDPSSAHQADKLFHQQGRKVFKELLPMIYQHLDEHLAEQALTPQSFKRLWLHQANINMNQFVVRKMLGDEVSPE
QAPVVLDEYANTASAGSVIAFHKYSSDFKAGDLGLLSSFGAGYSIGSVILQKR

Sequences:

>Translated_373_residues
MKQVVISGSGLFTPPYSISNEALVESFNAYVDIFNLENAGLIEQGHVAALSYSSSEFIEKASGIKHRYVMVKEGILDPEI
MMPLIPERSSDELSMQAEIGVEAALMALNNANLKAEQIDLVIVACAYTQRAYPAMAIEIQRALGTRGYGYDMQVACSSAT
FAIVAAANAIATGSASRVLVINPEICSAQVNYRDRDSHFIFGDVATALVLEEQSLVEPNKGFTILSSRCFTDYSNNIRSN
FGFLNRCDPSSAHQADKLFHQQGRKVFKELLPMIYQHLDEHLAEQALTPQSFKRLWLHQANINMNQFVVRKMLGDEVSPE
QAPVVLDEYANTASAGSVIAFHKYSSDFKAGDLGLLSSFGAGYSIGSVILQKR
>Mature_373_residues
MKQVVISGSGLFTPPYSISNEALVESFNAYVDIFNLENAGLIEQGHVAALSYSSSEFIEKASGIKHRYVMVKEGILDPEI
MMPLIPERSSDELSMQAEIGVEAALMALNNANLKAEQIDLVIVACAYTQRAYPAMAIEIQRALGTRGYGYDMQVACSSAT
FAIVAAANAIATGSASRVLVINPEICSAQVNYRDRDSHFIFGDVATALVLEEQSLVEPNKGFTILSSRCFTDYSNNIRSN
FGFLNRCDPSSAHQADKLFHQQGRKVFKELLPMIYQHLDEHLAEQALTPQSFKRLWLHQANINMNQFVVRKMLGDEVSPE
QAPVVLDEYANTASAGSVIAFHKYSSDFKAGDLGLLSSFGAGYSIGSVILQKR

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=318, Percent_Identity=27.9874213836478, Blast_Score=108, Evalue=5e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 40914; Mature: 40914

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQVVISGSGLFTPPYSISNEALVESFNAYVDIFNLENAGLIEQGHVAALSYSSSEFIEK
CCEEEEECCCCCCCCCCCCHHHHHHHHHHEEEEEECCCCCCCCCCCEEEEECCHHHHHHH
ASGIKHRYVMVKEGILDPEIMMPLIPERSSDELSMQAEIGVEAALMALNNANLKAEQIDL
HCCCCEEEEEEECCCCCHHHHHCCCCCCCCCCEEEEHHCCHHEEEEECCCCCCCHHHEEE
VIVACAYTQRAYPAMAIEIQRALGTRGYGYDMQVACSSATFAIVAAANAIATGSASRVLV
EEEEEEHHCCCCCHHHHHHHHHHCCCCCCCCEEEEECCCEEEEEEEHHHHCCCCCCEEEE
INPEICSAQVNYRDRDSHFIFGDVATALVLEEQSLVEPNKGFTILSSRCFTDYSNNIRSN
ECCCCCEEECCCCCCCCCEEEHHHHHHHHCCHHHHCCCCCCEEEEEHHHHHHHHCCHHHC
FGFLNRCDPSSAHQADKLFHQQGRKVFKELLPMIYQHLDEHLAEQALTPQSFKRLWLHQA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHC
NINMNQFVVRKMLGDEVSPEQAPVVLDEYANTASAGSVIAFHKYSSDFKAGDLGLLSSFG
CCCHHHHHHHHHHCCCCCCCCCCEEHHHHCCCCCCCCEEEEEECCCCCCCCCHHHHHHCC
AGYSIGSVILQKR
CCCCHHHHHEECC
>Mature Secondary Structure
MKQVVISGSGLFTPPYSISNEALVESFNAYVDIFNLENAGLIEQGHVAALSYSSSEFIEK
CCEEEEECCCCCCCCCCCCHHHHHHHHHHEEEEEECCCCCCCCCCCEEEEECCHHHHHHH
ASGIKHRYVMVKEGILDPEIMMPLIPERSSDELSMQAEIGVEAALMALNNANLKAEQIDL
HCCCCEEEEEEECCCCCHHHHHCCCCCCCCCCEEEEHHCCHHEEEEECCCCCCCHHHEEE
VIVACAYTQRAYPAMAIEIQRALGTRGYGYDMQVACSSATFAIVAAANAIATGSASRVLV
EEEEEEHHCCCCCHHHHHHHHHHCCCCCCCCEEEEECCCEEEEEEEHHHHCCCCCCEEEE
INPEICSAQVNYRDRDSHFIFGDVATALVLEEQSLVEPNKGFTILSSRCFTDYSNNIRSN
ECCCCCEEECCCCCCCCCEEEHHHHHHHHCCHHHHCCCCCCEEEEEHHHHHHHHCCHHHC
FGFLNRCDPSSAHQADKLFHQQGRKVFKELLPMIYQHLDEHLAEQALTPQSFKRLWLHQA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHC
NINMNQFVVRKMLGDEVSPEQAPVVLDEYANTASAGSVIAFHKYSSDFKAGDLGLLSSFG
CCCHHHHHHHHHHCCCCCCCCCCEEHHHHCCCCCCCCEEEEEECCCCCCCCCHHHHHHCC
AGYSIGSVILQKR
CCCCHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA