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The map label for this gene is cidA [H]

Identifier: 120597750

GI number: 120597750

Start: 1045477

End: 1045911

Strand: Direct

Name: cidA [H]

Synonym: Sputw3181_0920

Alternate gene names: 120597750

Gene position: 1045477-1045911 (Clockwise)

Preceding gene: 120597745

Following gene: 120597751

Centisome position: 22.2

GC content: 42.53

Gene sequence:

>435_bases
ATGTCATTCCTACAAGCCACAATATGTCGATGTCGTCATGGGGCTTTGCTGTTAATCCAAATCGGTCTCTTTTGTTTACT
GTCTCTTGCTTGTCATTGGTTTGCTATTTGGGCGCACTTACCCCTACCTGGCAGTGTACTAGGATTAGGTATCTTATTGA
TTTTACTTATATCAAAATTGATACCTGAGCGTGCTGTACAGCTTGGCGCTGCTTGGTTAATTGGTGAGCTATTACTGTTT
TTTATTCCACCTGTGATATCGGTTATCAAGTACGAAGGGCTGTTTGAGCAGTATGGTGTCAATATCATGTTTACGCTTGT
CATGGGGAGTATCTGTGTGATGGTGGGAACGGGCTTTGTTGTGGATAGAGTGTTTCGTTTTGAACGCCAGTTGAATATCA
AAAAGCATGCTCGTCGCCATGCTAAGGTTGTTTAG

Upstream 100 bases:

>100_bases
TCTTTAAATTCATGGATTACATTCTTAATATTCATTTTTTTTATTGAATAGACAAGCGGTAAAATGGTGTTATAGAAATT
TAGTGTTGATTGAGAACATC

Downstream 100 bases:

>100_bases
CCATGGCCGATTCAAAAGTGATGGATTTTCTAATGTCGCAAACCGTTTTAGCCTTAATCAGTTTATTGTTAACGGTATTT
TGTTACTACGGAGCTAAAAG

Product: LrgA family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 144; Mature: 143

Protein sequence:

>144_residues
MSFLQATICRCRHGALLLIQIGLFCLLSLACHWFAIWAHLPLPGSVLGLGILLILLISKLIPERAVQLGAAWLIGELLLF
FIPPVISVIKYEGLFEQYGVNIMFTLVMGSICVMVGTGFVVDRVFRFERQLNIKKHARRHAKVV

Sequences:

>Translated_144_residues
MSFLQATICRCRHGALLLIQIGLFCLLSLACHWFAIWAHLPLPGSVLGLGILLILLISKLIPERAVQLGAAWLIGELLLF
FIPPVISVIKYEGLFEQYGVNIMFTLVMGSICVMVGTGFVVDRVFRFERQLNIKKHARRHAKVV
>Mature_143_residues
SFLQATICRCRHGALLLIQIGLFCLLSLACHWFAIWAHLPLPGSVLGLGILLILLISKLIPERAVQLGAAWLIGELLLFF
IPPVISVIKYEGLFEQYGVNIMFTLVMGSICVMVGTGFVVDRVFRFERQLNIKKHARRHAKVV

Specific function: Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. W

COG id: COG1380

COG function: function code R; Putative effector of murein hydrolase LrgA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CidA/LrgA family. CidA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005538 [H]

Pfam domain/function: PF03788 LrgA [H]

EC number: NA

Molecular weight: Translated: 16143; Mature: 16012

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFLQATICRCRHGALLLIQIGLFCLLSLACHWFAIWAHLPLPGSVLGLGILLILLISKL
CCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
IPERAVQLGAAWLIGELLLFFIPPVISVIKYEGLFEQYGVNIMFTLVMGSICVMVGTGFV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
VDRVFRFERQLNIKKHARRHAKVV
HHHHHHHHHHCCHHHHHHHHHCCC
>Mature Secondary Structure 
SFLQATICRCRHGALLLIQIGLFCLLSLACHWFAIWAHLPLPGSVLGLGILLILLISKL
CHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
IPERAVQLGAAWLIGELLLFFIPPVISVIKYEGLFEQYGVNIMFTLVMGSICVMVGTGFV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
VDRVFRFERQLNIKKHARRHAKVV
HHHHHHHHHHCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA