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The map label for this gene is kdpE [H]

Identifier: 120597698

GI number: 120597698

Start: 981362

End: 982045

Strand: Direct

Name: kdpE [H]

Synonym: Sputw3181_0868

Alternate gene names: 120597698

Gene position: 981362-982045 (Clockwise)

Preceding gene: 120597697

Following gene: 120597700

Centisome position: 20.84

GC content: 44.88

Gene sequence:

>684_bases
GTGGCAATAAAAATCGTGGTTATCGATGATGAGACCCAAATACGCCGCATGTTGCGGATTGCACTCGCCAGTGAAGGTTA
TGATGTTACTGAGGCAGAAAATGGTCAGCAAGGACTCTCAGCTGTCGCTCGCCAGCAACCTGAATTAGTGATTTTGGATT
TAGGCTTGCCGGATATGGAAGGCCATCAAGTGCTACAGGAGTTACGGGGATGGTCCGATGTTGCTGTGATTGTATTGTCG
GTTCGCAATCAAGATAAGGAAAAAGTCGCAGCATTAGATGCAGGCGCGCAGGATTATGTAACTAAACCCTTTAGTGTGGA
AGAGTTACTGGCAAGGGTGCGGGCAATTTTAAGGGACCATATCAAACCTGAAAAATTACCCATATTAGATGATGGTAAGT
TGCAGATTGATTTAAGTCGTAGGTTAGTGAAAGTTGATAACCAAGTTATCGAACTCACACCCAAGGAATACGCGGTATTG
TCTAAATTGGCGTCGTCACCTAACTGCGTTGTTACTCAGACTCAGCTACTAAAGGAAATTTGGGGGCCAGCCCACACAGA
AGACACACATTATCTACGAATTGTGGTCAGTCACTTAAGGCAAAAATTAGGCGATTCCCCGAGTGAGCCTCAGTATATGC
GGACTGAACCTGGTGTCGGTTATCGTTTATATTTTGAGCTATAG

Upstream 100 bases:

>100_bases
GGCACTCGTTTTGAAGTTGAATTGCCGTTAGACTACCCTGTTCCTGGCTAATCATTTTTAGTCAAAATATCCTTACTAAA
CCACAGAATGGACTAGAGAC

Downstream 100 bases:

>100_bases
GTTATAGATATATTTTTACTTTGAACCTTAAGTGCTGCGGCTCATTTCGATTAATCGACTGTAGGTTCTGCGAAATTCGA
AACTAAGCGCGCCACCTTGG

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MAIKIVVIDDETQIRRMLRIALASEGYDVTEAENGQQGLSAVARQQPELVILDLGLPDMEGHQVLQELRGWSDVAVIVLS
VRNQDKEKVAALDAGAQDYVTKPFSVEELLARVRAILRDHIKPEKLPILDDGKLQIDLSRRLVKVDNQVIELTPKEYAVL
SKLASSPNCVVTQTQLLKEIWGPAHTEDTHYLRIVVSHLRQKLGDSPSEPQYMRTEPGVGYRLYFEL

Sequences:

>Translated_227_residues
MAIKIVVIDDETQIRRMLRIALASEGYDVTEAENGQQGLSAVARQQPELVILDLGLPDMEGHQVLQELRGWSDVAVIVLS
VRNQDKEKVAALDAGAQDYVTKPFSVEELLARVRAILRDHIKPEKLPILDDGKLQIDLSRRLVKVDNQVIELTPKEYAVL
SKLASSPNCVVTQTQLLKEIWGPAHTEDTHYLRIVVSHLRQKLGDSPSEPQYMRTEPGVGYRLYFEL
>Mature_226_residues
AIKIVVIDDETQIRRMLRIALASEGYDVTEAENGQQGLSAVARQQPELVILDLGLPDMEGHQVLQELRGWSDVAVIVLSV
RNQDKEKVAALDAGAQDYVTKPFSVEELLARVRAILRDHIKPEKLPILDDGKLQIDLSRRLVKVDNQVIELTPKEYAVLS
KLASSPNCVVTQTQLLKEIWGPAHTEDTHYLRIVVSHLRQKLGDSPSEPQYMRTEPGVGYRLYFEL

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=223, Percent_Identity=45.2914798206278, Blast_Score=203, Evalue=9e-54,
Organism=Escherichia coli, GI87082012, Length=221, Percent_Identity=36.1990950226244, Blast_Score=130, Evalue=6e-32,
Organism=Escherichia coli, GI1790552, Length=225, Percent_Identity=36, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1787375, Length=228, Percent_Identity=31.5789473684211, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=29.9559471365639, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1786599, Length=230, Percent_Identity=31.7391304347826, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI1788394, Length=221, Percent_Identity=30.316742081448, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1786784, Length=225, Percent_Identity=31.1111111111111, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1790863, Length=232, Percent_Identity=28.0172413793103, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1789402, Length=225, Percent_Identity=29.3333333333333, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI2367329, Length=225, Percent_Identity=32, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1790860, Length=224, Percent_Identity=32.1428571428571, Blast_Score=98, Evalue=4e-22,
Organism=Escherichia coli, GI1787229, Length=230, Percent_Identity=27.8260869565217, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI145693140, Length=231, Percent_Identity=27.7056277056277, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=37.3831775700935, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1790299, Length=125, Percent_Identity=33.6, Blast_Score=68, Evalue=4e-13,
Organism=Escherichia coli, GI1788191, Length=119, Percent_Identity=31.0924369747899, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25557; Mature: 25426

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIKIVVIDDETQIRRMLRIALASEGYDVTEAENGQQGLSAVARQQPELVILDLGLPDME
CEEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCC
GHQVLQELRGWSDVAVIVLSVRNQDKEKVAALDAGAQDYVTKPFSVEELLARVRAILRDH
HHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHCCCCHHHCCCCCCHHHHHHHHHHHHHHC
IKPEKLPILDDGKLQIDLSRRLVKVDNQVIELTPKEYAVLSKLASSPNCVVTQTQLLKEI
CCCCCCCEECCCEEEEHHHHHHHHHCCEEEEECCHHHHHHHHHHCCCCEEEEHHHHHHHH
WGPAHTEDTHYLRIVVSHLRQKLGDSPSEPQYMRTEPGVGYRLYFEL
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCEEEEEEC
>Mature Secondary Structure 
AIKIVVIDDETQIRRMLRIALASEGYDVTEAENGQQGLSAVARQQPELVILDLGLPDME
EEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCC
GHQVLQELRGWSDVAVIVLSVRNQDKEKVAALDAGAQDYVTKPFSVEELLARVRAILRDH
HHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHCCCCHHHCCCCCCHHHHHHHHHHHHHHC
IKPEKLPILDDGKLQIDLSRRLVKVDNQVIELTPKEYAVLSKLASSPNCVVTQTQLLKEI
CCCCCCCEECCCEEEEHHHHHHHHHCCEEEEECCHHHHHHHHHHCCCCEEEEHHHHHHHH
WGPAHTEDTHYLRIVVSHLRQKLGDSPSEPQYMRTEPGVGYRLYFEL
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1532388; 8905232; 9278503 [H]