Click here to switch to the map view.

The map label for this gene is fbp [H]

Identifier: 120597383

GI number: 120597383

Start: 603486

End: 603821

Strand: Direct

Name: fbp [H]

Synonym: Sputw3181_0552

Alternate gene names: 120597383

Gene position: 603486-603821 (Clockwise)

Preceding gene: 120597381

Following gene: 120597384

Centisome position: 12.82

GC content: 43.45

Gene sequence:

>336_bases
ATGGCGGAATTAGAAGTAATAGATCTAGTCGTTGGTGAGGGTAAAGAGGCAGTAAAAGGTGCACTGATCACCACACAATA
CCGCGGCTTTTTAGAAGATGGCACTCAATTTGATTCGTCCTATGATCGTCGACAAGCATTTCAGTGTGTTATTGGTACTG
GCCGTGTTATTAAAGGTTGGGATCAAGGTATTATGGGCATGAAAATTGGGGGAAAACGTAAGTTGTTAGTACCTGCCCAC
CTTGCCTATGGTGAGCGTCAAGTGGGGGCACATATCAAACCTCATTCAAATCTTATTTTTGAAATCGAATTGCTTGAGGT
GCTAACGCGCGACTAA

Upstream 100 bases:

>100_bases
CTGCAATAGCGCCGACAACCGTGAGCGTCGATGATAAAATCCGGTGCCAAGTGACTATCGCGTAATCAATAAAATACGAA
AAAGAAAAGAGAGCGAAAAA

Downstream 100 bases:

>100_bases
AAGACACTTGATTCGTTAGTGTGGCAACGCTGAGGGAAATTGCTACTTTTGTTGTACACGCTTTCGATGTATTACTACAA
AGAGTGTTTTACACTGAAAT

Product: peptidylprolyl isomerase, FKBP-type

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase; PPIase; Rotamase [H]

Number of amino acids: Translated: 111; Mature: 110

Protein sequence:

>111_residues
MAELEVIDLVVGEGKEAVKGALITTQYRGFLEDGTQFDSSYDRRQAFQCVIGTGRVIKGWDQGIMGMKIGGKRKLLVPAH
LAYGERQVGAHIKPHSNLIFEIELLEVLTRD

Sequences:

>Translated_111_residues
MAELEVIDLVVGEGKEAVKGALITTQYRGFLEDGTQFDSSYDRRQAFQCVIGTGRVIKGWDQGIMGMKIGGKRKLLVPAH
LAYGERQVGAHIKPHSNLIFEIELLEVLTRD
>Mature_110_residues
AELEVIDLVVGEGKEAVKGALITTQYRGFLEDGTQFDSSYDRRQAFQCVIGTGRVIKGWDQGIMGMKIGGKRKLLVPAHL
AYGERQVGAHIKPHSNLIFEIELLEVLTRD

Specific function: PPIases accelerate the folding of proteins [H]

COG id: COG0545

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 1

Gene ontology:

Cell location: Cytoplasm And Periplasmic Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Homo sapiens, GI206725530, Length=92, Percent_Identity=51.0869565217391, Blast_Score=97, Evalue=3e-21,
Organism=Homo sapiens, GI17149844, Length=92, Percent_Identity=51.0869565217391, Blast_Score=97, Evalue=3e-21,
Organism=Homo sapiens, GI17149842, Length=92, Percent_Identity=51.0869565217391, Blast_Score=97, Evalue=3e-21,
Organism=Homo sapiens, GI192448443, Length=97, Percent_Identity=41.2371134020619, Blast_Score=88, Evalue=2e-18,
Organism=Homo sapiens, GI17149836, Length=105, Percent_Identity=37.1428571428571, Blast_Score=80, Evalue=4e-16,
Organism=Homo sapiens, GI4503725, Length=105, Percent_Identity=37.1428571428571, Blast_Score=80, Evalue=4e-16,
Organism=Homo sapiens, GI33469985, Length=99, Percent_Identity=43.4343434343434, Blast_Score=78, Evalue=1e-15,
Organism=Homo sapiens, GI8923659, Length=91, Percent_Identity=43.956043956044, Blast_Score=73, Evalue=4e-14,
Organism=Homo sapiens, GI4758380, Length=105, Percent_Identity=36.1904761904762, Blast_Score=71, Evalue=2e-13,
Organism=Homo sapiens, GI224809329, Length=102, Percent_Identity=40.1960784313725, Blast_Score=71, Evalue=2e-13,
Organism=Homo sapiens, GI224809327, Length=102, Percent_Identity=40.1960784313725, Blast_Score=71, Evalue=2e-13,
Organism=Homo sapiens, GI4758384, Length=102, Percent_Identity=40.1960784313725, Blast_Score=71, Evalue=2e-13,
Organism=Homo sapiens, GI224809331, Length=102, Percent_Identity=40.1960784313725, Blast_Score=71, Evalue=2e-13,
Organism=Homo sapiens, GI4503729, Length=101, Percent_Identity=39.6039603960396, Blast_Score=71, Evalue=2e-13,
Organism=Homo sapiens, GI150010552, Length=110, Percent_Identity=38.1818181818182, Blast_Score=70, Evalue=4e-13,
Organism=Homo sapiens, GI4503727, Length=97, Percent_Identity=36.0824742268041, Blast_Score=66, Evalue=6e-12,
Organism=Homo sapiens, GI206725547, Length=108, Percent_Identity=37.037037037037, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI87082390, Length=97, Percent_Identity=43.298969072165, Blast_Score=78, Evalue=1e-16,
Organism=Escherichia coli, GI1789745, Length=97, Percent_Identity=39.1752577319588, Blast_Score=61, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17540882, Length=93, Percent_Identity=44.0860215053763, Blast_Score=87, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71993519, Length=89, Percent_Identity=47.1910112359551, Blast_Score=84, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17561782, Length=109, Percent_Identity=38.5321100917431, Blast_Score=72, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17561778, Length=101, Percent_Identity=41.5841584158416, Blast_Score=66, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6324194, Length=97, Percent_Identity=49.4845360824742, Blast_Score=98, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6320727, Length=93, Percent_Identity=50.5376344086022, Blast_Score=97, Evalue=6e-22,
Organism=Saccharomyces cerevisiae, GI6323566, Length=100, Percent_Identity=38, Blast_Score=76, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6323482, Length=100, Percent_Identity=39, Blast_Score=75, Evalue=2e-15,
Organism=Drosophila melanogaster, GI281363946, Length=94, Percent_Identity=44.6808510638298, Blast_Score=94, Evalue=1e-20,
Organism=Drosophila melanogaster, GI17352457, Length=94, Percent_Identity=44.6808510638298, Blast_Score=94, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24655568, Length=105, Percent_Identity=41.9047619047619, Blast_Score=92, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24647110, Length=104, Percent_Identity=42.3076923076923, Blast_Score=91, Evalue=1e-19,
Organism=Drosophila melanogaster, GI21356629, Length=98, Percent_Identity=43.8775510204082, Blast_Score=83, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24583150, Length=95, Percent_Identity=40, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 12329; Mature: 12198

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAELEVIDLVVGEGKEAVKGALITTQYRGFLEDGTQFDSSYDRRQAFQCVIGTGRVIKGW
CCCEEEEEEEECCCHHHHHCEEEEHHHCCHHCCCCCCCCCCCHHHHHHEEECCCCEEECC
DQGIMGMKIGGKRKLLVPAHLAYGERQVGAHIKPHSNLIFEIELLEVLTRD
CCCEEEEEECCCEEEEEEHHHCCCCCCCCCEECCCCCEEEEEEEHHHHHCC
>Mature Secondary Structure 
AELEVIDLVVGEGKEAVKGALITTQYRGFLEDGTQFDSSYDRRQAFQCVIGTGRVIKGW
CCEEEEEEEECCCHHHHHCEEEEHHHCCHHCCCCCCCCCCCHHHHHHEEECCCCEEECC
DQGIMGMKIGGKRKLLVPAHLAYGERQVGAHIKPHSNLIFEIELLEVLTRD
CCCEEEEEECCCEEEEEEHHHCCCCCCCCCEECCCCCEEEEEEEHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]