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The map label for this gene is zntR

Identifier: 120597374

GI number: 120597374

Start: 593960

End: 594430

Strand: Direct

Name: zntR

Synonym: Sputw3181_0543

Alternate gene names: 120597374

Gene position: 593960-594430 (Clockwise)

Preceding gene: 120597370

Following gene: 120597375

Centisome position: 12.61

GC content: 52.87

Gene sequence:

>471_bases
ATGTATCGAATTGGTGAGCTGGCCGATTTATGTGAGGTTAAGGCCGATACGCTGAGGTTTTACGAGAAGCACGGCCTACT
CGCGCCTTCGAGCCGCACTGAGTCTGGTTATCGCGTGTATACCGAGGCAGATGCTGCGCGGCTGCGTTTTATCCTGCGGG
CGAAGGCTGTGGGTTTTACCTTGAGTGAAATTAGCGAGCTGTTGTCTATCGATCTTGACAAGTCCAACTGGGCTTGTGCC
GATGTAAAAGGCATGGTCGACCTCAAGTTGGCGCAGGTGCAGGTTAAGATTGCCGAGTTACTGCATTTTCAAACCAGTTT
GCAGAGCCTGTCGGATGCCTGCTGTGGCGGGCCGCGTAGCGCCGAACACTGTTCGATTTTAGAAGCGCTGGAGTCGAGTA
CCGAGCGAGTACGCGTTGAGCATGATCATGGTGCAGATTGCACCACAACCCTAGAAAAGTCAGGGAATTAA

Upstream 100 bases:

>100_bases
TTAAAAATACCCCTTGACCTTGGAGTAGGCTCCAAGGTTTATACTCCGCCTATTGAGTTGAGATTGTTAACTTAAGGTCA
ACTTTGCAAAGGATAAAGCT

Downstream 100 bases:

>100_bases
TTATGTTACTGAAGAATTTTATCGATCTGTTTTTAGACTCTGCGCCTTGGTTGTTACTGGGCTTGATTTTGGCGGGGTTA
TTAAAAGTATTTGTGCCTAT

Product: zinc-responsive transcriptional regulator

Products: NA

Alternate protein names: Zn(II)-responsive regulator of zntA [H]

Number of amino acids: Translated: 156; Mature: 156

Protein sequence:

>156_residues
MYRIGELADLCEVKADTLRFYEKHGLLAPSSRTESGYRVYTEADAARLRFILRAKAVGFTLSEISELLSIDLDKSNWACA
DVKGMVDLKLAQVQVKIAELLHFQTSLQSLSDACCGGPRSAEHCSILEALESSTERVRVEHDHGADCTTTLEKSGN

Sequences:

>Translated_156_residues
MYRIGELADLCEVKADTLRFYEKHGLLAPSSRTESGYRVYTEADAARLRFILRAKAVGFTLSEISELLSIDLDKSNWACA
DVKGMVDLKLAQVQVKIAELLHFQTSLQSLSDACCGGPRSAEHCSILEALESSTERVRVEHDHGADCTTTLEKSGN
>Mature_156_residues
MYRIGELADLCEVKADTLRFYEKHGLLAPSSRTESGYRVYTEADAARLRFILRAKAVGFTLSEISELLSIDLDKSNWACA
DVKGMVDLKLAQVQVKIAELLHFQTSLQSLSDACCGGPRSAEHCSILEALESSTERVRVEHDHGADCTTTLEKSGN

Specific function: Zinc-responsive transcriptional regulator of zntA [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789687, Length=138, Percent_Identity=50.7246376811594, Blast_Score=144, Evalue=2e-36,
Organism=Escherichia coli, GI1786695, Length=127, Percent_Identity=34.6456692913386, Blast_Score=77, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358
- InterPro:   IPR011788 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 17195; Mature: 17195

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYRIGELADLCEVKADTLRFYEKHGLLAPSSRTESGYRVYTEADAARLRFILRAKAVGFT
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCC
LSEISELLSIDLDKSNWACADVKGMVDLKLAQVQVKIAELLHFQTSLQSLSDACCGGPRS
HHHHHHHHHCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
AEHCSILEALESSTERVRVEHDHGADCTTTLEKSGN
CHHHHHHHHHHCCHHEEEEECCCCCCCEEHHCCCCC
>Mature Secondary Structure
MYRIGELADLCEVKADTLRFYEKHGLLAPSSRTESGYRVYTEADAARLRFILRAKAVGFT
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCC
LSEISELLSIDLDKSNWACADVKGMVDLKLAQVQVKIAELLHFQTSLQSLSDACCGGPRS
HHHHHHHHHCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
AEHCSILEALESSTERVRVEHDHGADCTTTLEKSGN
CHHHHHHHHHHCCHHEEEEECCCCCCCEEHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]