Click here to switch to the map view.

The map label for this gene is coaD

Identifier: 120596893

GI number: 120596893

Start: 76556

End: 77047

Strand: Direct

Name: coaD

Synonym: Sputw3181_0060

Alternate gene names: 120596893

Gene position: 76556-77047 (Clockwise)

Preceding gene: 120596890

Following gene: 120596894

Centisome position: 1.63

GC content: 45.33

Gene sequence:

>492_bases
ATGCATACAAGAGCGATTTATCCAGGAACTTTCGATCCTATCACTAATGGTCATGTGGACTTGATAGAGCGTGCGGCTAA
ACTATTTAAACATGTGACTATTGGCATTGCGGCTAACCCTTCCAAGCAGCCTAGATTTACCCTTGAAGAGCGAGTTGAAT
TGGTCAATCGGGTAACTGCTCATTTGGATAATGTCGAGGTGGTGGGGTTTTCTGGGTTGCTAGTGGATTTTGCCAAGGAG
CAAAAGGCCAGTGTACTTGTGCGTGGGTTACGCGCGGTATCCGACTTTGAATATGAATTCCAATTAGCAAATATGAATCG
CAGATTGAGCCCTGATCTGGAAAGCGTGTTTTTAACGCCTGCCGAGGAAAACTCATTTATCTCTTCAACCTTAGTAAAGG
AAGTCGCTTTGCATGGTGGCGATGTGAGCCAGTTTGTTCACCCTGAAGTAACGGCTGCATTGGCGGCAAAGCTTAAGTTG
GTTAAACCTTAG

Upstream 100 bases:

>100_bases
AAAAATAATTGTATTCAACGGGTACACGTTGAGTCTGCGACGGATTGAAAGGGTGTTTTGGTGTCTTTAATGAATTATGA
CAGTGAGGATGTACTTTTCT

Downstream 100 bases:

>100_bases
ATTTTACCTGCGAACTAGATAGTTTTTACGTAGGAGTTTTGTGTTAACTTTGAGGCATTTTTGCCTTGTGATGATACTTA
AAAGGATGTTATGAAGGCTT

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT [H]

Number of amino acids: Translated: 163; Mature: 163

Protein sequence:

>163_residues
MHTRAIYPGTFDPITNGHVDLIERAAKLFKHVTIGIAANPSKQPRFTLEERVELVNRVTAHLDNVEVVGFSGLLVDFAKE
QKASVLVRGLRAVSDFEYEFQLANMNRRLSPDLESVFLTPAEENSFISSTLVKEVALHGGDVSQFVHPEVTAALAAKLKL
VKP

Sequences:

>Translated_163_residues
MHTRAIYPGTFDPITNGHVDLIERAAKLFKHVTIGIAANPSKQPRFTLEERVELVNRVTAHLDNVEVVGFSGLLVDFAKE
QKASVLVRGLRAVSDFEYEFQLANMNRRLSPDLESVFLTPAEENSFISSTLVKEVALHGGDVSQFVHPEVTAALAAKLKL
VKP
>Mature_163_residues
MHTRAIYPGTFDPITNGHVDLIERAAKLFKHVTIGIAANPSKQPRFTLEERVELVNRVTAHLDNVEVVGFSGLLVDFAKE
QKASVLVRGLRAVSDFEYEFQLANMNRRLSPDLESVFLTPAEENSFISSTLVKEVALHGGDVSQFVHPEVTAALAAKLKL
VKP

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate [H]

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family [H]

Homologues:

Organism=Escherichia coli, GI1790065, Length=158, Percent_Identity=66.4556962025316, Blast_Score=221, Evalue=2e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2 [H]

EC number: =2.7.7.3 [H]

Molecular weight: Translated: 18007; Mature: 18007

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTRAIYPGTFDPITNGHVDLIERAAKLFKHVTIGIAANPSKQPRFTLEERVELVNRVTA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHEEEECCCCCCCCCCHHHHHHHHHHHHH
HLDNVEVVGFSGLLVDFAKEQKASVLVRGLRAVSDFEYEFQLANMNRRLSPDLESVFLTP
HCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHEEECC
AEENSFISSTLVKEVALHGGDVSQFVHPEVTAALAAKLKLVKP
CCCCHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MHTRAIYPGTFDPITNGHVDLIERAAKLFKHVTIGIAANPSKQPRFTLEERVELVNRVTA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHEEEECCCCCCCCCCHHHHHHHHHHHHH
HLDNVEVVGFSGLLVDFAKEQKASVLVRGLRAVSDFEYEFQLANMNRRLSPDLESVFLTP
HCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHEEECC
AEENSFISSTLVKEVALHGGDVSQFVHPEVTAALAAKLKLVKP
CCCCHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA