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The map label for this gene is atpB

Identifier: 119947329

GI number: 119947329

Start: 4552528

End: 4553331

Strand: Reverse

Name: atpB

Synonym: Ping_3736

Alternate gene names: 119947329

Gene position: 4553331-4552528 (Counterclockwise)

Preceding gene: 119947330

Following gene: 119947328

Centisome position: 99.86

GC content: 37.56

Gene sequence:

>804_bases
GTGTTAACTTCTTCCGGGTATATCCAACATCATCTAACAAATGCACAAATGTGTACTGTTGATGGTAGCATTGCATTTAA
TTATGCTTGTGCTGATGCTGGATTTTGGACTTGGCACATTGACTCTCTCCTATTTTCAGTTGGCCTAGGTGTTCTATTCT
TGTTTGTTTTTTACAAGGTAGGGCAAAAAGCAACAACGGGTGTCCCCGGCAAACTCCAATGTGCAGTTGAAATGCTCATG
GAATTTGTTAGTAACGCGGTAAAAGATTCTTTTCACGGTCGTAGCCCTGTTATTGCACCATTAGCTCTGACCATATTCGT
TTGGATTTTACTAATGAATACGATGGATCTAATACCTGTTGACTTTATTCCTGAAGCCGCCAAACAAATATTAGGTGTTC
CTTACCTGAAAGTTGTACCAACAACGGATATGAATATTACTTTTGGATTATCATTAAGTGTATTTGCATTAATTGTTTTT
TACTCCATTAAGATCAAAGGAATTACAGGGTTTGTTAAAGAATTAACCCTACAACCTTTTAATCATTGGGCATTTATTCC
AGTTAACTTTATTTTGGAAACAATTGCTTTGATTGCGAAGCCGATATCTTTATCTCTTCGTTTGTTTGGTAATCTGTATG
CAGGTGAGTTGATCTTTATTCTAATTGCATTAATGCCTTGGTGGAGCCAAGCGGCACTTTCTGTGCCATGGGCAATATTC
CACATCCTGGTGATTGTGCTACAGGCCTTTATTTTTATGATGCTGACAATTGTTTACCTCAGTATGGCTCATGAAGATCA
TTAA

Upstream 100 bases:

>100_bases
TCTTTTTATATTTCATTTTTACTTTTAGTAGCATCTCAATGGTTAGCACCTTTCTTTTTTTACGATAATAATGGGATAAA
AAATGACCGCTAAAGATGAA

Downstream 100 bases:

>100_bases
ATTTTAATTAAACAATTTTACAAACTTTTAAATACTCGGAGAAAAAAATGGAAATTATTATCAGCTCTACGGCTATTGCT
GTTGCACTTATGATTGGTCT

Product: F0F1 ATP synthase subunit A

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F0 sector subunit a; F-ATPase subunit 6

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MLTSSGYIQHHLTNAQMCTVDGSIAFNYACADAGFWTWHIDSLLFSVGLGVLFLFVFYKVGQKATTGVPGKLQCAVEMLM
EFVSNAVKDSFHGRSPVIAPLALTIFVWILLMNTMDLIPVDFIPEAAKQILGVPYLKVVPTTDMNITFGLSLSVFALIVF
YSIKIKGITGFVKELTLQPFNHWAFIPVNFILETIALIAKPISLSLRLFGNLYAGELIFILIALMPWWSQAALSVPWAIF
HILVIVLQAFIFMMLTIVYLSMAHEDH

Sequences:

>Translated_267_residues
MLTSSGYIQHHLTNAQMCTVDGSIAFNYACADAGFWTWHIDSLLFSVGLGVLFLFVFYKVGQKATTGVPGKLQCAVEMLM
EFVSNAVKDSFHGRSPVIAPLALTIFVWILLMNTMDLIPVDFIPEAAKQILGVPYLKVVPTTDMNITFGLSLSVFALIVF
YSIKIKGITGFVKELTLQPFNHWAFIPVNFILETIALIAKPISLSLRLFGNLYAGELIFILIALMPWWSQAALSVPWAIF
HILVIVLQAFIFMMLTIVYLSMAHEDH
>Mature_267_residues
MLTSSGYIQHHLTNAQMCTVDGSIAFNYACADAGFWTWHIDSLLFSVGLGVLFLFVFYKVGQKATTGVPGKLQCAVEMLM
EFVSNAVKDSFHGRSPVIAPLALTIFVWILLMNTMDLIPVDFIPEAAKQILGVPYLKVVPTTDMNITFGLSLSVFALIVF
YSIKIKGITGFVKELTLQPFNHWAFIPVNFILETIALIAKPISLSLRLFGNLYAGELIFILIALMPWWSQAALSVPWAIF
HILVIVLQAFIFMMLTIVYLSMAHEDH

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family

Homologues:

Organism=Escherichia coli, GI1790176, Length=267, Percent_Identity=62.9213483146067, Blast_Score=325, Evalue=1e-90,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATP6_PSYIN (A1T0Z5)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_945009.1
- ProteinModelPortal:   A1T0Z5
- SMR:   A1T0Z5
- STRING:   A1T0Z5
- GeneID:   4624825
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_3736
- eggNOG:   COG0356
- HOGENOM:   HBG734175
- OMA:   AGELVFM
- PhylomeDB:   A1T0Z5
- ProtClustDB:   PRK05815
- BioCyc:   PING357804:PING_3736-MONOMER
- HAMAP:   MF_01393
- InterPro:   IPR000568
- InterPro:   IPR023011
- Gene3D:   G3DSA:1.20.120.220
- PANTHER:   PTHR11410
- PRINTS:   PR00123
- TIGRFAMs:   TIGR01131

Pfam domain/function: PF00119 ATP-synt_A; SSF81336 ATPase_F0_A

EC number: 3.6.3.14

Molecular weight: Translated: 29770; Mature: 29770

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: PS00449 ATPASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1bc419d8)-; HASH(0x1b7dd1a4)-; HASH(0x1b947664)-; HASH(0x1b196e08)-; HASH(0x15ef9830)-;

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTSSGYIQHHLTNAQMCTVDGSIAFNYACADAGFWTWHIDSLLFSVGLGVLFLFVFYKV
CCCCCCCHHHHCCCCEEEEECCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GQKATTGVPGKLQCAVEMLMEFVSNAVKDSFHGRSPVIAPLALTIFVWILLMNTMDLIPV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
DFIPEAAKQILGVPYLKVVPTTDMNITFGLSLSVFALIVFYSIKIKGITGFVKELTLQPF
HHHHHHHHHHHCCCCEEEECCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NHWAFIPVNFILETIALIAKPISLSLRLFGNLYAGELIFILIALMPWWSQAALSVPWAIF
CCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCHHHHH
HILVIVLQAFIFMMLTIVYLSMAHEDH
HHHHHHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure
MLTSSGYIQHHLTNAQMCTVDGSIAFNYACADAGFWTWHIDSLLFSVGLGVLFLFVFYKV
CCCCCCCHHHHCCCCEEEEECCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GQKATTGVPGKLQCAVEMLMEFVSNAVKDSFHGRSPVIAPLALTIFVWILLMNTMDLIPV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
DFIPEAAKQILGVPYLKVVPTTDMNITFGLSLSVFALIVFYSIKIKGITGFVKELTLQPF
HHHHHHHHHHHCCCCEEEECCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NHWAFIPVNFILETIALIAKPISLSLRLFGNLYAGELIFILIALMPWWSQAALSVPWAIF
CCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCHHHHH
HILVIVLQAFIFMMLTIVYLSMAHEDH
HHHHHHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA