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The map label for this gene is atpA2

Identifier: 119947325

GI number: 119947325

Start: 4549615

End: 4551156

Strand: Reverse

Name: atpA2

Synonym: Ping_3732

Alternate gene names: 119947325

Gene position: 4551156-4549615 (Counterclockwise)

Preceding gene: 119947326

Following gene: 119947324

Centisome position: 99.81

GC content: 41.83

Gene sequence:

>1542_bases
ATGCAACTGAATTCCACTGAAATCAGCGACCTTATCAAGCAGCGAATTGGAAAATTCGAGGCAGTAAGTGAAGCTCGTAA
TGAAGGTACAATCGTTTCCGTAAGCGATGGTATTGTTCGTATCAATGGCCTTGCTGAATGTATGCAGGGTGAGATGATTG
AGCTACCAAATGGTGGCTTTGCGATGGCACTTAACCTTGAGCGTGACTCTGTTGGTGCAGTAGTAATGGGACCTTTCCGT
GATCTTCGTGAAGGTCAAAAGGTTAAATCAACTGGACGTATTCTTGAAGTGCCAGTAGGTAAAGGTTTGTTAGGTCGTGT
TGTAAACACACTTGGCGCACCCATTGATGGTAAAGGCCCGATTGAAAATGACGGTTATTCTCCTATTGAAGTAATAGCAC
CTGGCGTAATCGATCGTAAATCTGTTGATCAACCAGTACAAACTGGCTGGAAGTCAATCGATTCAATGGTTCCAATTGGT
CGTGGCCAACGTGAATTAATCATTGGTGACCGTCAAGTTGGTAAAACGGCTATTGCAATCGATGCAATCATTAACCAAAA
ACACACCGGATTATTTTCAATCTATGTTGCGATTGGTCAGAAAGCATCAACCATTGCAAATGTGGTAAATAAACTTGAAG
AGCATGGCGCATTAGAAAATACTATTGTTGTTGTTGCTTCTGCATCTGAAACCGCTGCGCTGCAATACCTGGCTCCTTAT
GCAGGTTGTTCTATGGGTGAATACTTCCGTGACCGTGGTGAAGATGCATTGATCGTATATGATGATTTGTCTAAACAAGC
TGTTGCTTATCGTCAAATTTCACTGCTGCTTAAACGTCCGCCTGGTCGTGAAGCATACCCTGGTGATGTTTTCTACCTTC
ACTCTCGTCTTCTTGAACGTGCATCTCGTGTAAGCGCTGCTTACGTTGAGGCCTTTACTAAAGGTGCAGTGAAAGGTAAA
ACCGGTTCTTTAACTGCGTTACCTATCATTGAAACACAAGGTGGCGATGTATCAGCATTTGTACCTACTAACGTAATATC
TATTACTGACGGTCAGATATTTTTAACAACTGAGCTATTTAATAGTGGTATTCGTCCTGCGGTTGATCCTGGTATTTCAG
TATCACGTGTTGGTGGTTCTGCGCAATGTAAAGTGATCAAAAAGCTAGCGGGTGGTATTCGTACCGCACTGGCTCAATAC
CGTGAATTAGCGGCGTTTGCACAGTTTGCTTCGGATCTTGATGAAACAACACGTAAACAGCTTGACCACGGTAAGAAAGT
AACTGAATTAATGAAGCAAAAACAATATGCTCCAATGTCAGTTGCTGAACAAGCGTTATCACTGTTTTCAGCAGAGAAAG
GTTATCTAACTGATGTTGATGTTGAAAAAGTATTAGACTTTGAATCATCTCTGATCTCTTATGCTAAAACTGAGCATGCT
GAATTCTATGCTCAACTTAATGAAACCGGTGATTACAGCAAAGAAATTGAAGGTCAATTCCATGCTATATTGGAAACTTT
CAAAGCGACGCAAACCTGGTAA

Upstream 100 bases:

>100_bases
CGGAATGGTAGTTACTGTGGGTGACTTAGTGATTGATAGCTCTGCTAAAGGTCAACTAGGTCGATTATCTAATACTTTAC
AATCTTAATGGGAAATTGGC

Downstream 100 bases:

>100_bases
TTAGTTAACTACTTAAACGGTTAATTAATCATTAATTAGGAGCTAGAGAATGGCCGGCGATAAAGAAATTAGAAATAAGA
TCGCGAGTGTTAAAAACACT

Product: ATP synthase F1, alpha subunit

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha 2; F-ATPase subunit alpha 2

Number of amino acids: Translated: 513; Mature: 513

Protein sequence:

>513_residues
MQLNSTEISDLIKQRIGKFEAVSEARNEGTIVSVSDGIVRINGLAECMQGEMIELPNGGFAMALNLERDSVGAVVMGPFR
DLREGQKVKSTGRILEVPVGKGLLGRVVNTLGAPIDGKGPIENDGYSPIEVIAPGVIDRKSVDQPVQTGWKSIDSMVPIG
RGQRELIIGDRQVGKTAIAIDAIINQKHTGLFSIYVAIGQKASTIANVVNKLEEHGALENTIVVVASASETAALQYLAPY
AGCSMGEYFRDRGEDALIVYDDLSKQAVAYRQISLLLKRPPGREAYPGDVFYLHSRLLERASRVSAAYVEAFTKGAVKGK
TGSLTALPIIETQGGDVSAFVPTNVISITDGQIFLTTELFNSGIRPAVDPGISVSRVGGSAQCKVIKKLAGGIRTALAQY
RELAAFAQFASDLDETTRKQLDHGKKVTELMKQKQYAPMSVAEQALSLFSAEKGYLTDVDVEKVLDFESSLISYAKTEHA
EFYAQLNETGDYSKEIEGQFHAILETFKATQTW

Sequences:

>Translated_513_residues
MQLNSTEISDLIKQRIGKFEAVSEARNEGTIVSVSDGIVRINGLAECMQGEMIELPNGGFAMALNLERDSVGAVVMGPFR
DLREGQKVKSTGRILEVPVGKGLLGRVVNTLGAPIDGKGPIENDGYSPIEVIAPGVIDRKSVDQPVQTGWKSIDSMVPIG
RGQRELIIGDRQVGKTAIAIDAIINQKHTGLFSIYVAIGQKASTIANVVNKLEEHGALENTIVVVASASETAALQYLAPY
AGCSMGEYFRDRGEDALIVYDDLSKQAVAYRQISLLLKRPPGREAYPGDVFYLHSRLLERASRVSAAYVEAFTKGAVKGK
TGSLTALPIIETQGGDVSAFVPTNVISITDGQIFLTTELFNSGIRPAVDPGISVSRVGGSAQCKVIKKLAGGIRTALAQY
RELAAFAQFASDLDETTRKQLDHGKKVTELMKQKQYAPMSVAEQALSLFSAEKGYLTDVDVEKVLDFESSLISYAKTEHA
EFYAQLNETGDYSKEIEGQFHAILETFKATQTW
>Mature_513_residues
MQLNSTEISDLIKQRIGKFEAVSEARNEGTIVSVSDGIVRINGLAECMQGEMIELPNGGFAMALNLERDSVGAVVMGPFR
DLREGQKVKSTGRILEVPVGKGLLGRVVNTLGAPIDGKGPIENDGYSPIEVIAPGVIDRKSVDQPVQTGWKSIDSMVPIG
RGQRELIIGDRQVGKTAIAIDAIINQKHTGLFSIYVAIGQKASTIANVVNKLEEHGALENTIVVVASASETAALQYLAPY
AGCSMGEYFRDRGEDALIVYDDLSKQAVAYRQISLLLKRPPGREAYPGDVFYLHSRLLERASRVSAAYVEAFTKGAVKGK
TGSLTALPIIETQGGDVSAFVPTNVISITDGQIFLTTELFNSGIRPAVDPGISVSRVGGSAQCKVIKKLAGGIRTALAQY
RELAAFAQFASDLDETTRKQLDHGKKVTELMKQKQYAPMSVAEQALSLFSAEKGYLTDVDVEKVLDFESSLISYAKTEHA
EFYAQLNETGDYSKEIEGQFHAILETFKATQTW

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI50345984, Length=513, Percent_Identity=53.411306042885, Blast_Score=545, Evalue=1e-155,
Organism=Homo sapiens, GI4757810, Length=513, Percent_Identity=53.411306042885, Blast_Score=545, Evalue=1e-155,
Organism=Homo sapiens, GI32189394, Length=438, Percent_Identity=25.7990867579909, Blast_Score=122, Evalue=9e-28,
Organism=Homo sapiens, GI19913428, Length=315, Percent_Identity=27.3015873015873, Blast_Score=109, Evalue=5e-24,
Organism=Homo sapiens, GI19913426, Length=314, Percent_Identity=27.0700636942675, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI19913424, Length=334, Percent_Identity=24.5508982035928, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1790172, Length=513, Percent_Identity=78.9473684210526, Blast_Score=858, Evalue=0.0,
Organism=Escherichia coli, GI1790170, Length=404, Percent_Identity=26.980198019802, Blast_Score=131, Evalue=1e-31,
Organism=Escherichia coli, GI1788251, Length=387, Percent_Identity=24.8062015503876, Blast_Score=103, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71988063, Length=515, Percent_Identity=54.1747572815534, Blast_Score=555, Evalue=1e-158,
Organism=Caenorhabditis elegans, GI71988080, Length=515, Percent_Identity=54.1747572815534, Blast_Score=554, Evalue=1e-158,
Organism=Caenorhabditis elegans, GI71988074, Length=513, Percent_Identity=50.4873294346979, Blast_Score=501, Evalue=1e-142,
Organism=Caenorhabditis elegans, GI17510931, Length=373, Percent_Identity=27.3458445040214, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI25144756, Length=438, Percent_Identity=24.4292237442922, Blast_Score=115, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17570191, Length=303, Percent_Identity=27.7227722772277, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=58, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17565854, Length=254, Percent_Identity=25.5905511811024, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319370, Length=513, Percent_Identity=53.9961013645224, Blast_Score=563, Evalue=1e-161,
Organism=Saccharomyces cerevisiae, GI6322581, Length=404, Percent_Identity=26.2376237623762, Blast_Score=124, Evalue=5e-29,
Organism=Saccharomyces cerevisiae, GI6319603, Length=312, Percent_Identity=29.4871794871795, Blast_Score=115, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24658560, Length=514, Percent_Identity=53.1128404669261, Blast_Score=540, Evalue=1e-154,
Organism=Drosophila melanogaster, GI24638766, Length=439, Percent_Identity=26.1958997722096, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI281361666, Length=306, Percent_Identity=29.0849673202614, Blast_Score=119, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24646341, Length=306, Percent_Identity=29.0849673202614, Blast_Score=119, Evalue=6e-27,
Organism=Drosophila melanogaster, GI17136796, Length=306, Percent_Identity=29.0849673202614, Blast_Score=119, Evalue=6e-27,
Organism=Drosophila melanogaster, GI28574560, Length=436, Percent_Identity=27.2935779816514, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24583992, Length=326, Percent_Identity=24.8466257668712, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24583988, Length=255, Percent_Identity=26.6666666666667, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24583986, Length=255, Percent_Identity=26.6666666666667, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24583984, Length=255, Percent_Identity=26.6666666666667, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI20129479, Length=239, Percent_Identity=27.6150627615063, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPA2_PSYIN (A1T0Z1)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_945005.1
- ProteinModelPortal:   A1T0Z1
- SMR:   A1T0Z1
- STRING:   A1T0Z1
- GeneID:   4624881
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_3732
- eggNOG:   COG0056
- HOGENOM:   HBG565875
- OMA:   EMALTLW
- PhylomeDB:   A1T0Z1
- BioCyc:   PING357804:PING_3732-MONOMER
- HAMAP:   MF_01346
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF3
- TIGRFAMs:   TIGR00962

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 55473; Mature: 55473

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLNSTEISDLIKQRIGKFEAVSEARNEGTIVSVSDGIVRINGLAECMQGEMIELPNGGF
CCCCHHHHHHHHHHHHCHHHHHHHHCCCCCEEEECCCEEEECCHHHHHCCCEEECCCCCE
AMALNLERDSVGAVVMGPFRDLREGQKVKSTGRILEVPVGKGLLGRVVNTLGAPIDGKGP
EEEEEECCCCCCEEEECCHHHHHCCHHHHHCCCEEEECCCCCHHHHHHHHHCCCCCCCCC
IENDGYSPIEVIAPGVIDRKSVDQPVQTGWKSIDSMVPIGRGQRELIIGDRQVGKTAIAI
CCCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEECCCHHCCHHHHH
DAIINQKHTGLFSIYVAIGQKASTIANVVNKLEEHGALENTIVVVASASETAALQYLAPY
HHHHCCCCCCCEEEEEHHCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHH
AGCSMGEYFRDRGEDALIVYDDLSKQAVAYRQISLLLKRPPGREAYPGDVFYLHSRLLER
CCCCHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
ASRVSAAYVEAFTKGAVKGKTGSLTALPIIETQGGDVSAFVPTNVISITDGQIFLTTELF
HHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCCEEEEHHHH
NSGIRPAVDPGISVSRVGGSAQCKVIKKLAGGIRTALAQYRELAAFAQFASDLDETTRKQ
HCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDHGKKVTELMKQKQYAPMSVAEQALSLFSAEKGYLTDVDVEKVLDFESSLISYAKTEHA
HHCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
EFYAQLNETGDYSKEIEGQFHAILETFKATQTW
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQLNSTEISDLIKQRIGKFEAVSEARNEGTIVSVSDGIVRINGLAECMQGEMIELPNGGF
CCCCHHHHHHHHHHHHCHHHHHHHHCCCCCEEEECCCEEEECCHHHHHCCCEEECCCCCE
AMALNLERDSVGAVVMGPFRDLREGQKVKSTGRILEVPVGKGLLGRVVNTLGAPIDGKGP
EEEEEECCCCCCEEEECCHHHHHCCHHHHHCCCEEEECCCCCHHHHHHHHHCCCCCCCCC
IENDGYSPIEVIAPGVIDRKSVDQPVQTGWKSIDSMVPIGRGQRELIIGDRQVGKTAIAI
CCCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEECCCHHCCHHHHH
DAIINQKHTGLFSIYVAIGQKASTIANVVNKLEEHGALENTIVVVASASETAALQYLAPY
HHHHCCCCCCCEEEEEHHCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHH
AGCSMGEYFRDRGEDALIVYDDLSKQAVAYRQISLLLKRPPGREAYPGDVFYLHSRLLER
CCCCHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
ASRVSAAYVEAFTKGAVKGKTGSLTALPIIETQGGDVSAFVPTNVISITDGQIFLTTELF
HHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCCEEEEHHHH
NSGIRPAVDPGISVSRVGGSAQCKVIKKLAGGIRTALAQYRELAAFAQFASDLDETTRKQ
HCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDHGKKVTELMKQKQYAPMSVAEQALSLFSAEKGYLTDVDVEKVLDFESSLISYAKTEHA
HHCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
EFYAQLNETGDYSKEIEGQFHAILETFKATQTW
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA