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The map label for this gene is atpD2

Identifier: 119947323

GI number: 119947323

Start: 4547272

End: 4548669

Strand: Reverse

Name: atpD2

Synonym: Ping_3730

Alternate gene names: 119947323

Gene position: 4548669-4547272 (Counterclockwise)

Preceding gene: 119947324

Following gene: 119947322

Centisome position: 99.76

GC content: 43.13

Gene sequence:

>1398_bases
ATGAGTACAGGTAAAATCATTCAGGTTATCGGTGCTGTTGTGGATGTTGAATTCCCACAAGAAACTGTGCCGAATATATA
CAGTGCATTGATCGTGACTGCAAAGAATCTAACCATGGAAGTTCAGCAACAAATTGGCGGCGGCGTTGTACGTTGTATCG
CTATGGGTGCTTCTGATGGTTTAAGTCGCGGTTTAGATGTCACTGATACAGGTAAACCAATTACAGTACCCGTTGGTACG
GCAACGTTAGGCCGAATCATGAATGTACTGGGCGAGCCTATTGATATGTGTGGTGAAATTGGTGCAACTGAGCATTATGG
AATTCACCGCGAAGCCCCTACATACGAAGAGCAATCAGCTTCTGTCGCTACACTAGAAGTAGGTATTAAAGTTATAGACT
TAATATGCCCATTCTCTAAAGGTGGTAAAATCGGCCTATTTGGCGGTGCGGGTGTTGGTAAAACAGTTAACATGATGGAA
CTTATCAATAATATCGCTTTAAAACATTCAGGTTTGTCTGTTTTTGCCGGTGTTGGTGAGCGTACTCGTGAAGGTAACGA
TTTCTACTTTGAAATGCAGGAAGCCGGTGTTGTTAACGTTGAAAAACCTGAGTTATCAAAAGTAGCGATGGTTTACGGTC
AAATGAATGAGCCACCAGGAAACCGTTTACGTGTTGCCCTGACTGGTTTAACTATGGCTGAACGTTTCCGTGATGAAGGT
AAAGACGTGTTATTATTTATTGATAATATATATCGTTATACCCTTGCAGGAACTGAAGTATCTGCGTTATTAGGCCGTAT
GCCTTCTGCTGTTGGTTATCAACCAACACTTGCGGAAGAGATGGGTGTTCTGCAAGAACGTATTACTTCAACTAAGACGG
GTTCTATTACATCAATTCAGGCGGTATATGTACCTGCAGATGATTTAACGGATCCGGCTCCGGCAACAACCTTTGCTCAC
TTAGACGCAACAGTTGTACTTAACCGTAGCATCGCATCAATGGGTTTATACCCGGCGATCGATCCCTTAGATTCTACCTC
TCGTCAACTTGATCCATTAGTTGTTGGCCAAGAGCACTATGATATCGCACGTGGCGTACAGGGCACCCTGCAACGTTATA
AAGAGCTGAAAGATATTATTGCGATTCTGGGTATGGATGAATTATCTGAAGACGATAAACTGGTCGTATCTCGCGCACGT
AAAATCGGCAATTTCTTAACTCAGGCTTATCACGTAGCAGAAGTATTTACTGGTGATCCGGGGATGTACGTACCACTTAA
AGACACATTAGCTGGCTTTAAAGGGTTACTCGCTGGGGATTATGATGATCTTCCTGAGCAAGCGTTCCTATACATAGGCG
CGATTGAAGAAGCTGTTGAAAAAGCGAAAAAGATGTAA

Upstream 100 bases:

>100_bases
CCAATAAAGCACGTCAATCTGCAATTACTCAGGAACTTTCTGAGATTTGTAGTGGTGCGGCTGCGGTATAAGCAGATTAA
CAAATTTTAGAGGATCAGAG

Downstream 100 bases:

>100_bases
TAGCTGGAGATAACTATGACTAAAGCAATGACTACACATTTAGATGTTGTAAGTGCTGAAGAATCTCTTTTTTCTGGGCG
CGTTTCACATCTGCAAGTTT

Product: F0F1 ATP synthase subunit beta

Products: NA

Alternate protein names: ATP synthase F1 sector subunit beta 2; F-ATPase subunit beta 2

Number of amino acids: Translated: 465; Mature: 464

Protein sequence:

>465_residues
MSTGKIIQVIGAVVDVEFPQETVPNIYSALIVTAKNLTMEVQQQIGGGVVRCIAMGASDGLSRGLDVTDTGKPITVPVGT
ATLGRIMNVLGEPIDMCGEIGATEHYGIHREAPTYEEQSASVATLEVGIKVIDLICPFSKGGKIGLFGGAGVGKTVNMME
LINNIALKHSGLSVFAGVGERTREGNDFYFEMQEAGVVNVEKPELSKVAMVYGQMNEPPGNRLRVALTGLTMAERFRDEG
KDVLLFIDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSIQAVYVPADDLTDPAPATTFAH
LDATVVLNRSIASMGLYPAIDPLDSTSRQLDPLVVGQEHYDIARGVQGTLQRYKELKDIIAILGMDELSEDDKLVVSRAR
KIGNFLTQAYHVAEVFTGDPGMYVPLKDTLAGFKGLLAGDYDDLPEQAFLYIGAIEEAVEKAKKM

Sequences:

>Translated_465_residues
MSTGKIIQVIGAVVDVEFPQETVPNIYSALIVTAKNLTMEVQQQIGGGVVRCIAMGASDGLSRGLDVTDTGKPITVPVGT
ATLGRIMNVLGEPIDMCGEIGATEHYGIHREAPTYEEQSASVATLEVGIKVIDLICPFSKGGKIGLFGGAGVGKTVNMME
LINNIALKHSGLSVFAGVGERTREGNDFYFEMQEAGVVNVEKPELSKVAMVYGQMNEPPGNRLRVALTGLTMAERFRDEG
KDVLLFIDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSIQAVYVPADDLTDPAPATTFAH
LDATVVLNRSIASMGLYPAIDPLDSTSRQLDPLVVGQEHYDIARGVQGTLQRYKELKDIIAILGMDELSEDDKLVVSRAR
KIGNFLTQAYHVAEVFTGDPGMYVPLKDTLAGFKGLLAGDYDDLPEQAFLYIGAIEEAVEKAKKM
>Mature_464_residues
STGKIIQVIGAVVDVEFPQETVPNIYSALIVTAKNLTMEVQQQIGGGVVRCIAMGASDGLSRGLDVTDTGKPITVPVGTA
TLGRIMNVLGEPIDMCGEIGATEHYGIHREAPTYEEQSASVATLEVGIKVIDLICPFSKGGKIGLFGGAGVGKTVNMMEL
INNIALKHSGLSVFAGVGERTREGNDFYFEMQEAGVVNVEKPELSKVAMVYGQMNEPPGNRLRVALTGLTMAERFRDEGK
DVLLFIDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSIQAVYVPADDLTDPAPATTFAHL
DATVVLNRSIASMGLYPAIDPLDSTSRQLDPLVVGQEHYDIARGVQGTLQRYKELKDIIAILGMDELSEDDKLVVSRARK
IGNFLTQAYHVAEVFTGDPGMYVPLKDTLAGFKGLLAGDYDDLPEQAFLYIGAIEEAVEKAKKM

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits

COG id: COG0055

COG function: function code C; F0F1-type ATP synthase, beta subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI32189394, Length=467, Percent_Identity=67.4518201284797, Blast_Score=621, Evalue=1e-178,
Organism=Homo sapiens, GI19913424, Length=321, Percent_Identity=27.1028037383178, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI19913428, Length=367, Percent_Identity=24.2506811989101, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI19913426, Length=367, Percent_Identity=23.7057220708447, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI50345984, Length=310, Percent_Identity=23.5483870967742, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI4757810, Length=310, Percent_Identity=23.5483870967742, Blast_Score=79, Evalue=1e-14,
Organism=Escherichia coli, GI1790170, Length=467, Percent_Identity=78.372591006424, Blast_Score=749, Evalue=0.0,
Organism=Escherichia coli, GI1788251, Length=312, Percent_Identity=29.8076923076923, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1790172, Length=347, Percent_Identity=25.3602305475504, Blast_Score=105, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI25144756, Length=467, Percent_Identity=65.0963597430407, Blast_Score=600, Evalue=1e-172,
Organism=Caenorhabditis elegans, GI17565854, Length=310, Percent_Identity=29.0322580645161, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17510931, Length=361, Percent_Identity=24.9307479224377, Blast_Score=98, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17570191, Length=359, Percent_Identity=24.7910863509749, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71988080, Length=374, Percent_Identity=22.9946524064171, Blast_Score=87, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71988063, Length=374, Percent_Identity=22.9946524064171, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI71988074, Length=437, Percent_Identity=21.5102974828375, Blast_Score=70, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6322581, Length=460, Percent_Identity=66.304347826087, Blast_Score=605, Evalue=1e-174,
Organism=Saccharomyces cerevisiae, GI6319603, Length=385, Percent_Identity=25.7142857142857, Blast_Score=96, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6319370, Length=380, Percent_Identity=24.7368421052632, Blast_Score=85, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6320016, Length=294, Percent_Identity=25.1700680272109, Blast_Score=84, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24638766, Length=466, Percent_Identity=66.0944206008584, Blast_Score=609, Evalue=1e-174,
Organism=Drosophila melanogaster, GI28574560, Length=466, Percent_Identity=62.6609442060086, Blast_Score=574, Evalue=1e-164,
Organism=Drosophila melanogaster, GI20129479, Length=346, Percent_Identity=24.8554913294798, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24583992, Length=334, Percent_Identity=27.5449101796407, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24583988, Length=334, Percent_Identity=27.5449101796407, Blast_Score=105, Evalue=8e-23,
Organism=Drosophila melanogaster, GI24583986, Length=334, Percent_Identity=27.5449101796407, Blast_Score=105, Evalue=8e-23,
Organism=Drosophila melanogaster, GI24583984, Length=334, Percent_Identity=27.5449101796407, Blast_Score=105, Evalue=8e-23,
Organism=Drosophila melanogaster, GI281361666, Length=368, Percent_Identity=25, Blast_Score=96, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24646341, Length=368, Percent_Identity=25, Blast_Score=96, Evalue=6e-20,
Organism=Drosophila melanogaster, GI17136796, Length=368, Percent_Identity=25, Blast_Score=96, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24638768, Length=92, Percent_Identity=52.1739130434783, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24658560, Length=374, Percent_Identity=22.192513368984, Blast_Score=80, Evalue=3e-15,

Paralogues:

None

Copy number: 10836 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPB2_PSYIN (A1T0Y9)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_945003.1
- ProteinModelPortal:   A1T0Y9
- SMR:   A1T0Y9
- STRING:   A1T0Y9
- GeneID:   4624879
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_3730
- eggNOG:   COG0055
- HOGENOM:   HBG565875
- OMA:   IGQEHYD
- PhylomeDB:   A1T0Y9
- ProtClustDB:   PRK09280
- BioCyc:   PING357804:PING_3730-MONOMER
- HAMAP:   MF_01347
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR005722
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF8
- SMART:   SM00382
- TIGRFAMs:   TIGR01039

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 49973; Mature: 49842

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTGKIIQVIGAVVDVEFPQETVPNIYSALIVTAKNLTMEVQQQIGGGVVRCIAMGASDG
CCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHEEECCCCH
LSRGLDVTDTGKPITVPVGTATLGRIMNVLGEPIDMCGEIGATEHYGIHREAPTYEEQSA
HHCCCCCCCCCCEEEEECCHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCCCCCCC
SVATLEVGIKVIDLICPFSKGGKIGLFGGAGVGKTVNMMELINNIALKHSGLSVFAGVGE
CEEEHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEECCCC
RTREGNDFYFEMQEAGVVNVEKPELSKVAMVYGQMNEPPGNRLRVALTGLTMAERFRDEG
CCCCCCCEEEEEECCCEEECCCCCHHHHHHHHCCCCCCCCCEEEEEEECHHHHHHHHHCC
KDVLLFIDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSIQ
CEEEEEEECHHHEEECCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEE
AVYVPADDLTDPAPATTFAHLDATVVLNRSIASMGLYPAIDPLDSTSRQLDPLVVGQEHY
EEEECCCCCCCCCCCCCHHHCCEEEEEECHHHHCCCCCCCCCCCCCHHHCCCEEECCCHH
DIARGVQGTLQRYKELKDIIAILGMDELSEDDKLVVSRARKIGNFLTQAYHVAEVFTGDP
HHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCC
GMYVPLKDTLAGFKGLLAGDYDDLPEQAFLYIGAIEEAVEKAKKM
CEEEEHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
STGKIIQVIGAVVDVEFPQETVPNIYSALIVTAKNLTMEVQQQIGGGVVRCIAMGASDG
CCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHEEECCCCH
LSRGLDVTDTGKPITVPVGTATLGRIMNVLGEPIDMCGEIGATEHYGIHREAPTYEEQSA
HHCCCCCCCCCCEEEEECCHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCCCCCCC
SVATLEVGIKVIDLICPFSKGGKIGLFGGAGVGKTVNMMELINNIALKHSGLSVFAGVGE
CEEEHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEECCCC
RTREGNDFYFEMQEAGVVNVEKPELSKVAMVYGQMNEPPGNRLRVALTGLTMAERFRDEG
CCCCCCCEEEEEECCCEEECCCCCHHHHHHHHCCCCCCCCCEEEEEEECHHHHHHHHHCC
KDVLLFIDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSIQ
CEEEEEEECHHHEEECCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEE
AVYVPADDLTDPAPATTFAHLDATVVLNRSIASMGLYPAIDPLDSTSRQLDPLVVGQEHY
EEEECCCCCCCCCCCCCHHHCCEEEEEECHHHHCCCCCCCCCCCCCHHHCCCEEECCCHH
DIARGVQGTLQRYKELKDIIAILGMDELSEDDKLVVSRARKIGNFLTQAYHVAEVFTGDP
HHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCC
GMYVPLKDTLAGFKGLLAGDYDDLPEQAFLYIGAIEEAVEKAKKM
CEEEEHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA