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The map label for this gene is macB [H]

Identifier: 119947303

GI number: 119947303

Start: 4516160

End: 4517374

Strand: Reverse

Name: macB [H]

Synonym: Ping_3709

Alternate gene names: 119947303

Gene position: 4517374-4516160 (Counterclockwise)

Preceding gene: 119947304

Following gene: 119947302

Centisome position: 99.07

GC content: 47.41

Gene sequence:

>1215_bases
ATGAAAACGTCACTGCGTGATATTACCGTTTTTTCCTGGGGTGCTCTGAGCGGTTATCCGACCCGGACAATATTGATGTT
AACTGCGATGGCTATCGGGGTTGCCTCGGTCATTATGTTAACCGCTTTAGGGGAGGGTGCCCGGCGTTATGTCAGCAATG
AATTTAGCTCATTAGGTACCAATCTGGTGATTGTTTTTCCTGGTTATTCTGAAACATCAGGGCTTAATTCCGTTGCTATG
GTGGGGACAACTCCTCGTGATCTGACCCTTGATGATGCGCAGGCATTAACCCGTAACCTAAATATTCGCCGTATAGCGCC
GATCAATATCGGTTCAATTAATGCCAGTTTTCAGGGCCGATCACGTGAAGTACCCATTATTGGCAGTAACGCCGAGCTAT
TAAATATTCGCCATTGGCAACTGGCCCAGGGGCATTTTTTACCTGCCGGTGATTTAGATCGTGCTACTCCTGTTTGTGTG
ATTGGGCGTAATATAAAAGATCAACTATTTGCAGCACAAGCAGCGTTAGGTCAATGGATACGTCTGGGGGATCGGCGTTT
TCGGGTGATCGGCATTATGGCCTCAACAGGGCGGTCGATTGGTGTGGATGTACAGGATACTATTATTATTCCGGTGGCAT
CTGCGCAGCAGTTATTTAACAGCGCTTCACTGTTTCGTATTCTGCTGGAAGTTAAAACCCGTTCTGCCATCGAGTCAGTC
AAGCAATCCACTATCGAGCTGTTAAAAGAGCGTCATCAGGGCAAACGGGATGTGACCGTGATCACCCAGGATGCGGTACT
GAAAACCTTTGATCGTATATTAGGCGCACTAACTTATGCTATTGGCGGCATTGCGGCAATCAGCCTGGCTGTCGCCGGTA
TTTTAATTATGAATGTGATGCTGGTCGCCGTCTCTCAACGTACTGCAGAAATTGGTTTACTCAAAGCCTTAGGTGCACCT
TCGCGTCAGATTGTTTATTTGATTTTATTCGAAGCCATTATGTTATCGATCTTCGGCGCTGTGCTCGGTGTATTATTGGG
CGAACTGGGTTGTTTTGCTATCAGACTGGTTTTTCCTGCTTTGCCTGCCTATTCTCCGCTCTGGGCGGTATTGACTGCGG
TTGCTGTCAGTCTATTAGCCGGATTTATTTTTAGTTTACTGCCGGCACAACAAGCTGCGCGTCTGAATCCTGTTCTCGCC
CTGACGGGTAAATAG

Upstream 100 bases:

>100_bases
TTGTGACTCATGACAGCAATATTGGCGGGCGGGCAACGCGGCAATTAAAAATGGTTGATGGCCGTATTGAATCGGATCAG
CCTTTATCTCCGGCCTGCTT

Downstream 100 bases:

>100_bases
ATTATGCAGCTGCGCGACCTTCTACATTTAACCACTTCATCCCTGATTGCACATCGTCTGCGCAGTTTTTTATCTGCATT
AGGCATTGCAGTGGGCGTTG

Product: ABC transporter permease protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MKTSLRDITVFSWGALSGYPTRTILMLTAMAIGVASVIMLTALGEGARRYVSNEFSSLGTNLVIVFPGYSETSGLNSVAM
VGTTPRDLTLDDAQALTRNLNIRRIAPINIGSINASFQGRSREVPIIGSNAELLNIRHWQLAQGHFLPAGDLDRATPVCV
IGRNIKDQLFAAQAALGQWIRLGDRRFRVIGIMASTGRSIGVDVQDTIIIPVASAQQLFNSASLFRILLEVKTRSAIESV
KQSTIELLKERHQGKRDVTVITQDAVLKTFDRILGALTYAIGGIAAISLAVAGILIMNVMLVAVSQRTAEIGLLKALGAP
SRQIVYLILFEAIMLSIFGAVLGVLLGELGCFAIRLVFPALPAYSPLWAVLTAVAVSLLAGFIFSLLPAQQAARLNPVLA
LTGK

Sequences:

>Translated_404_residues
MKTSLRDITVFSWGALSGYPTRTILMLTAMAIGVASVIMLTALGEGARRYVSNEFSSLGTNLVIVFPGYSETSGLNSVAM
VGTTPRDLTLDDAQALTRNLNIRRIAPINIGSINASFQGRSREVPIIGSNAELLNIRHWQLAQGHFLPAGDLDRATPVCV
IGRNIKDQLFAAQAALGQWIRLGDRRFRVIGIMASTGRSIGVDVQDTIIIPVASAQQLFNSASLFRILLEVKTRSAIESV
KQSTIELLKERHQGKRDVTVITQDAVLKTFDRILGALTYAIGGIAAISLAVAGILIMNVMLVAVSQRTAEIGLLKALGAP
SRQIVYLILFEAIMLSIFGAVLGVLLGELGCFAIRLVFPALPAYSPLWAVLTAVAVSLLAGFIFSLLPAQQAARLNPVLA
LTGK
>Mature_404_residues
MKTSLRDITVFSWGALSGYPTRTILMLTAMAIGVASVIMLTALGEGARRYVSNEFSSLGTNLVIVFPGYSETSGLNSVAM
VGTTPRDLTLDDAQALTRNLNIRRIAPINIGSINASFQGRSREVPIIGSNAELLNIRHWQLAQGHFLPAGDLDRATPVCV
IGRNIKDQLFAAQAALGQWIRLGDRRFRVIGIMASTGRSIGVDVQDTIIIPVASAQQLFNSASLFRILLEVKTRSAIESV
KQSTIELLKERHQGKRDVTVITQDAVLKTFDRILGALTYAIGGIAAISLAVAGILIMNVMLVAVSQRTAEIGLLKALGAP
SRQIVYLILFEAIMLSIFGAVLGVLLGELGCFAIRLVFPALPAYSPLWAVLTAVAVSLLAGFIFSLLPAQQAARLNPVLA
LTGK

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=403, Percent_Identity=30.0248138957816, Blast_Score=144, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 43276; Mature: 43276

Theoretical pI: Translated: 10.56; Mature: 10.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTSLRDITVFSWGALSGYPTRTILMLTAMAIGVASVIMLTALGEGARRYVSNEFSSLGT
CCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCC
NLVIVFPGYSETSGLNSVAMVGTTPRDLTLDDAQALTRNLNIRRIAPINIGSINASFQGR
CEEEEECCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHCCCEEEEECEEECCCCCCCCCC
SREVPIIGSNAELLNIRHWQLAQGHFLPAGDLDRATPVCVIGRNIKDQLFAAQAALGQWI
CCCCCEECCCCCEEEEEEEEECCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHH
RLGDRRFRVIGIMASTGRSIGVDVQDTIIIPVASAQQLFNSASLFRILLEVKTRSAIESV
HHCCCEEEEEEEEECCCCEECCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KQSTIELLKERHQGKRDVTVITQDAVLKTFDRILGALTYAIGGIAAISLAVAGILIMNVM
HHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVAVSQRTAEIGLLKALGAPSRQIVYLILFEAIMLSIFGAVLGVLLGELGCFAIRLVFPA
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LPAYSPLWAVLTAVAVSLLAGFIFSLLPAQQAARLNPVLALTGK
CCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCEEEECCC
>Mature Secondary Structure
MKTSLRDITVFSWGALSGYPTRTILMLTAMAIGVASVIMLTALGEGARRYVSNEFSSLGT
CCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCC
NLVIVFPGYSETSGLNSVAMVGTTPRDLTLDDAQALTRNLNIRRIAPINIGSINASFQGR
CEEEEECCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHCCCEEEEECEEECCCCCCCCCC
SREVPIIGSNAELLNIRHWQLAQGHFLPAGDLDRATPVCVIGRNIKDQLFAAQAALGQWI
CCCCCEECCCCCEEEEEEEEECCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHH
RLGDRRFRVIGIMASTGRSIGVDVQDTIIIPVASAQQLFNSASLFRILLEVKTRSAIESV
HHCCCEEEEEEEEECCCCEECCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KQSTIELLKERHQGKRDVTVITQDAVLKTFDRILGALTYAIGGIAAISLAVAGILIMNVM
HHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVAVSQRTAEIGLLKALGAPSRQIVYLILFEAIMLSIFGAVLGVLLGELGCFAIRLVFPA
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LPAYSPLWAVLTAVAVSLLAGFIFSLLPAQQAARLNPVLALTGK
CCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 14500908 [H]