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The map label for this gene is htxE [H]

Identifier: 119947289

GI number: 119947289

Start: 4501966

End: 4502973

Strand: Reverse

Name: htxE [H]

Synonym: Ping_3693

Alternate gene names: 119947289

Gene position: 4502973-4501966 (Counterclockwise)

Preceding gene: 119947290

Following gene: 119947288

Centisome position: 98.76

GC content: 40.67

Gene sequence:

>1008_bases
ATGAATAAAAACACTCAAAACCATATAAAACGTGATCACAGTCAATGGCAAACCTATCAAGCTATCACGCCAAAAACTGT
CCTGTTTTTATTTTTAGCCTTTGTGCTCTTAGCTTGGTCTGGGCAGAATACCGAAATGGATAAAGCTGCAATTGAAACTA
GTAAGGCCGTTCTGTCTGCAGTTGGTATTGGTGATTCTGAGGTGTTAAATGGCGTGTCTAAATTTGCCAGTCAGGCTTTT
CCAATTCAATTGCAAACACGGACTGAATTAAGCCGTATTGAAGGGCTAGATTTGCAACACTTACCTTGGCTCTCTTATAT
TAAAGAAGGCGTTTCTCGTGAATATTATATAGATACTGATACTTGGACAGAAGAAAAAGCGCAATACTTAATTGAACCCC
TTGGCTACTTAAAAAAAGTGTTGTGGATGATGTGGGAAACGATTGAAATGGGCTTCTGGGGAACCATTATTTCGATTGTT
ATTTCTTTGCCATTAGGTATTTTAGCGGCTCGTAACTACTCTCCACACCCTATTGTATATCATGTCGCACGTGCCTGGCT
AAGTTTTCACCGTTCAATGCCTGAACTGATTGTGGCTTTATTTTTAGTGCTTATCTATGGTTTTGGCCCGATTGCAGGTG
TGTTGGCCCTGGCGATTCATACCTCGGGGGTCTTAGGTAAATTCTTTGCCGATGAGATTGAAAATGCTGCTAAAGGCCCG
CAAATGGCACTGAGTTCAGCAGGTGCTAATGCAATTAAAGTCTTGCGTTATGCCGTCTTTCCTCAAGTTTTACCCGCTTG
GATTGCCTCTGTTCAATATATCTTTGAGCGTAATATCCGTACTGCAACTGTACTCGGCATTGTCGGTGCAGGCGGTATTG
GTATGGAGCTAAAAGGCCGTTGGGATATATTCGATTATGACTATGTTGCCACTATTTTATTAATTGTTTTTATTACTGTT
GTAGTGCTTGAGTTTTTCTCACAGAAACTGCGTAAGAAAACACTTTAA

Upstream 100 bases:

>100_bases
CCATTGAACGCGAAAATTTAGACAAACAACACAGTCAGTCCTCTGAAACTATTAAAGAGCCAGCACAACCAAGGATCGTT
AAAATGAAGGAGGCCAGCGC

Downstream 100 bases:

>100_bases
AGGGAATCTTAAATGAATAAAACTTGTCGAAAAATACCACGAAGTGCATGGATTAGAGCCTTAAAACTGGTGCCCGTAGA
TGAAATTAAAGCGCTAATTG

Product: ABC phosphonate transporter inner membrane protein

Products: 3-phospho-serine [Cytoplasm]; phosphite [Cytoplasm]; ADP; phosphate [Cytoplasm]; alkylphosphonate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MNKNTQNHIKRDHSQWQTYQAITPKTVLFLFLAFVLLAWSGQNTEMDKAAIETSKAVLSAVGIGDSEVLNGVSKFASQAF
PIQLQTRTELSRIEGLDLQHLPWLSYIKEGVSREYYIDTDTWTEEKAQYLIEPLGYLKKVLWMMWETIEMGFWGTIISIV
ISLPLGILAARNYSPHPIVYHVARAWLSFHRSMPELIVALFLVLIYGFGPIAGVLALAIHTSGVLGKFFADEIENAAKGP
QMALSSAGANAIKVLRYAVFPQVLPAWIASVQYIFERNIRTATVLGIVGAGGIGMELKGRWDIFDYDYVATILLIVFITV
VVLEFFSQKLRKKTL

Sequences:

>Translated_335_residues
MNKNTQNHIKRDHSQWQTYQAITPKTVLFLFLAFVLLAWSGQNTEMDKAAIETSKAVLSAVGIGDSEVLNGVSKFASQAF
PIQLQTRTELSRIEGLDLQHLPWLSYIKEGVSREYYIDTDTWTEEKAQYLIEPLGYLKKVLWMMWETIEMGFWGTIISIV
ISLPLGILAARNYSPHPIVYHVARAWLSFHRSMPELIVALFLVLIYGFGPIAGVLALAIHTSGVLGKFFADEIENAAKGP
QMALSSAGANAIKVLRYAVFPQVLPAWIASVQYIFERNIRTATVLGIVGAGGIGMELKGRWDIFDYDYVATILLIVFITV
VVLEFFSQKLRKKTL
>Mature_335_residues
MNKNTQNHIKRDHSQWQTYQAITPKTVLFLFLAFVLLAWSGQNTEMDKAAIETSKAVLSAVGIGDSEVLNGVSKFASQAF
PIQLQTRTELSRIEGLDLQHLPWLSYIKEGVSREYYIDTDTWTEEKAQYLIEPLGYLKKVLWMMWETIEMGFWGTIISIV
ISLPLGILAARNYSPHPIVYHVARAWLSFHRSMPELIVALFLVLIYGFGPIAGVLALAIHTSGVLGKFFADEIENAAKGP
QMALSSAGANAIKVLRYAVFPQVLPAWIASVQYIFERNIRTATVLGIVGAGGIGMELKGRWDIFDYDYVATILLIVFITV
VVLEFFSQKLRKKTL

Specific function: Probably forms part of a binding-protein-dependent hypophosphite transporter [H]

COG id: COG3639

COG function: function code P; ABC-type phosphate/phosphonate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 37591; Mature: 37591

Theoretical pI: Translated: 8.62; Mature: 8.62

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKNTQNHIKRDHSQWQTYQAITPKTVLFLFLAFVLLAWSGQNTEMDKAAIETSKAVLSA
CCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
VGIGDSEVLNGVSKFASQAFPIQLQTRTELSRIEGLDLQHLPWLSYIKEGVSREYYIDTD
HCCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCCCHHHHHHHCCCCCEEECCC
TWTEEKAQYLIEPLGYLKKVLWMMWETIEMGFWGTIISIVISLPLGILAARNYSPHPIVY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
HVARAWLSFHRSMPELIVALFLVLIYGFGPIAGVLALAIHTSGVLGKFFADEIENAAKGP
HHHHHHHHHHHCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
QMALSSAGANAIKVLRYAVFPQVLPAWIASVQYIFERNIRTATVLGIVGAGGIGMELKGR
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCEECCC
WDIFDYDYVATILLIVFITVVVLEFFSQKLRKKTL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNKNTQNHIKRDHSQWQTYQAITPKTVLFLFLAFVLLAWSGQNTEMDKAAIETSKAVLSA
CCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
VGIGDSEVLNGVSKFASQAFPIQLQTRTELSRIEGLDLQHLPWLSYIKEGVSREYYIDTD
HCCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCCCHHHHHHHCCCCCEEECCC
TWTEEKAQYLIEPLGYLKKVLWMMWETIEMGFWGTIISIVISLPLGILAARNYSPHPIVY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
HVARAWLSFHRSMPELIVALFLVLIYGFGPIAGVLALAIHTSGVLGKFFADEIENAAKGP
HHHHHHHHHHHCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
QMALSSAGANAIKVLRYAVFPQVLPAWIASVQYIFERNIRTATVLGIVGAGGIGMELKGR
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCEECCC
WDIFDYDYVATILLIVFITVVVLEFFSQKLRKKTL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; 3-phospho-serine [Periplasm]; phosphite [Periplasm]; H2O; phosphate [Periplasm]; alkylphosphonate [Periplasm] [C]

Specific reaction: H2O + ATP + 3-phospho-serine [Periplasm] = ADP + phosphate + 3-phospho-serine [Cytoplasm] ATP + phosphite [Periplasm] + H2O = phosphite [Cytoplasm] + ADP + phosphate phosphate [Periplasm] + ATP + H2O = ADP + phosphate [Cytoplasm] + phosphate [Cytoplasm] A

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9791102 [H]