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The map label for this gene is ald2 [H]

Identifier: 119947207

GI number: 119947207

Start: 4419589

End: 4420704

Strand: Direct

Name: ald2 [H]

Synonym: Ping_3605

Alternate gene names: 119947207

Gene position: 4419589-4420704 (Clockwise)

Preceding gene: 119947206

Following gene: 119947210

Centisome position: 96.93

GC content: 41.22

Gene sequence:

>1116_bases
ATGATTGTTGGCGTCCCTAAAGAAATTAAAAACCACGAATATCGTGTAGGTATGGTTCCAGGTAGCGTACGTGAATTAAC
CAATCATGGGCATCAGGTTATTGTTGAGACAAATGCCGGTTTAGGCATAGGTTTCAGTGATCAGGACTACATTAATGTTG
GTGCATCAATACAAAAAAATGCGGCAGAAGTCTTCGCCAGCGCTGACATGATAGTTAAGGTAAAAGAACCTCAAGCAGTT
GAACGTGCTATGTTGCGTGAAGGACAAATTTTATTTACTTACCTTCACTTGGCACCTGATCTTCCGCAAACTGAAGATTT
GATTAAATCAAAAGCAATTTGTATTGCCTATGAAACAGTTACTGACAATCAAGGTGGTTTACCTCTTTTAGCCCCAATGT
CAGAGGTTGCGGGACGCATGTCAATTCAAGCAGGTGCCCAAGCTCTTGAAAAATCAAATGCAGGCCGTGGTATGTTATTA
GGTGGTGTTCCTGGTGTTGCTCCTGCCAAGGTCGTCATTATTGGTGGCGGAATGGTTGGTAATAATGCAGCACAAATGGC
CGTAGGCATGGGTGCTGAAGTGGTTATTCTAGATCGTAATGTTAATGTGTTACGTCGTCTTGATGCGCAGTTTGGTAATA
AAATAAAAACGGTCTATTCAACAGCGGAAGCGCTTGAAGAACATGTTCTTGAAGCCGATTTAGTAATTGGCGGAGTACTG
GTTGCCGGCGCAGCTGCCCCTAAATTAGTTACAGCTGAACATATTAAAAACATGAAAGCGGGCTCTGCTATTGTTGATGT
TGCAATTGATCAAGGTGGCTGTATTGCTACGTCAAAAGCAACAACACACGCAGATCCAACCTTTATTGTTGATGATGTAG
TGCACTACTGTGTTGCTAATATGCCCGGTGCTGTTCCACTGACATCAACCTTTGCATTGAATAATGCAACACTGCCCTTT
ATTATAAATCTTGCTAATAAAGGTTATAAAGAAGCTTTATTAAGTGACCAGAATTTCTTAAATGGCCTAAATGTTATCAA
TGGTAAGATAACTTGTGCCAGCGTGGCAGAAAACTTAGGATTTGAGTTTGTTGATCCTAAAGTCGCATTAGCATAA

Upstream 100 bases:

>100_bases
ATAAAACTACAAAGGCAAAAAAACTTAGTAGCACAATCTAGATAAAGACCTTTAAACTAGGTTTAAATATTTATTAAATC
AAACCATAACGGAGTGTATT

Downstream 100 bases:

>100_bases
CCTTTATTGAGCGCCTCCATGAGGTGGCGCTTTTTCTGCATTAGCATTTTATGATCAACTGGCTATTTACCTTAACCTCT
TCCATTACCACATAAGTCCG

Product: alanine dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 371; Mature: 371

Protein sequence:

>371_residues
MIVGVPKEIKNHEYRVGMVPGSVRELTNHGHQVIVETNAGLGIGFSDQDYINVGASIQKNAAEVFASADMIVKVKEPQAV
ERAMLREGQILFTYLHLAPDLPQTEDLIKSKAICIAYETVTDNQGGLPLLAPMSEVAGRMSIQAGAQALEKSNAGRGMLL
GGVPGVAPAKVVIIGGGMVGNNAAQMAVGMGAEVVILDRNVNVLRRLDAQFGNKIKTVYSTAEALEEHVLEADLVIGGVL
VAGAAAPKLVTAEHIKNMKAGSAIVDVAIDQGGCIATSKATTHADPTFIVDDVVHYCVANMPGAVPLTSTFALNNATLPF
IINLANKGYKEALLSDQNFLNGLNVINGKITCASVAENLGFEFVDPKVALA

Sequences:

>Translated_371_residues
MIVGVPKEIKNHEYRVGMVPGSVRELTNHGHQVIVETNAGLGIGFSDQDYINVGASIQKNAAEVFASADMIVKVKEPQAV
ERAMLREGQILFTYLHLAPDLPQTEDLIKSKAICIAYETVTDNQGGLPLLAPMSEVAGRMSIQAGAQALEKSNAGRGMLL
GGVPGVAPAKVVIIGGGMVGNNAAQMAVGMGAEVVILDRNVNVLRRLDAQFGNKIKTVYSTAEALEEHVLEADLVIGGVL
VAGAAAPKLVTAEHIKNMKAGSAIVDVAIDQGGCIATSKATTHADPTFIVDDVVHYCVANMPGAVPLTSTFALNNATLPF
IINLANKGYKEALLSDQNFLNGLNVINGKITCASVAENLGFEFVDPKVALA
>Mature_371_residues
MIVGVPKEIKNHEYRVGMVPGSVRELTNHGHQVIVETNAGLGIGFSDQDYINVGASIQKNAAEVFASADMIVKVKEPQAV
ERAMLREGQILFTYLHLAPDLPQTEDLIKSKAICIAYETVTDNQGGLPLLAPMSEVAGRMSIQAGAQALEKSNAGRGMLL
GGVPGVAPAKVVIIGGGMVGNNAAQMAVGMGAEVVILDRNVNVLRRLDAQFGNKIKTVYSTAEALEEHVLEADLVIGGVL
VAGAAAPKLVTAEHIKNMKAGSAIVDVAIDQGGCIATSKATTHADPTFIVDDVVHYCVANMPGAVPLTSTFALNNATLPF
IINLANKGYKEALLSDQNFLNGLNVINGKITCASVAENLGFEFVDPKVALA

Specific function: May play a role in cell wall synthesis as L-alanine is an important constituent of the peptidoglycan layer [H]

COG id: COG0686

COG function: function code E; Alanine dehydrogenase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AlaDH/PNT family [H]

Homologues:

Organism=Homo sapiens, GI122939155, Length=347, Percent_Identity=29.971181556196, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI122939153, Length=347, Percent_Identity=29.971181556196, Blast_Score=114, Evalue=1e-25,
Organism=Escherichia coli, GI1787887, Length=333, Percent_Identity=29.4294294294294, Blast_Score=106, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17550456, Length=344, Percent_Identity=30.2325581395349, Blast_Score=132, Evalue=3e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007698
- InterPro:   IPR008142
- InterPro:   IPR008143
- InterPro:   IPR007886
- InterPro:   IPR008141 [H]

Pfam domain/function: PF01262 AlaDh_PNT_C; PF05222 AlaDh_PNT_N [H]

EC number: =1.4.1.1 [H]

Molecular weight: Translated: 38888; Mature: 38888

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: PS00837 ALADH_PNT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVGVPKEIKNHEYRVGMVPGSVRELTNHGHQVIVETNAGLGIGFSDQDYINVGASIQKN
CCCCCCHHHCCCCEEEEECCCHHHHHHCCCCEEEEECCCCEECCCCCCCCEEECCCHHHH
AAEVFASADMIVKVKEPQAVERAMLREGQILFTYLHLAPDLPQTEDLIKSKAICIAYETV
HHHHHHCCCEEEEECCCHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHCCEEEEEEEEE
TDNQGGLPLLAPMSEVAGRMSIQAGAQALEKSNAGRGMLLGGVPGVAPAKVVIIGGGMVG
ECCCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEEECCEEC
NNAAQMAVGMGAEVVILDRNVNVLRRLDAQFGNKIKTVYSTAEALEEHVLEADLVIGGVL
CCHHHHHCCCCCEEEEEECCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAGAAAPKLVTAEHIKNMKAGSAIVDVAIDQGGCIATSKATTHADPTFIVDDVVHYCVAN
HHCCCCCCEEEHHHHHCCCCCCEEEEEEECCCCEEEECCCCCCCCCCHHHHHHHHHHHHC
MPGAVPLTSTFALNNATLPFIINLANKGYKEALLSDQNFLNGLNVINGKITCASVAENLG
CCCCCCCEEEEEECCCCCEEEEEECCCCHHHHHHCCHHHHCCCEEECCEEEHHHHHHHCC
FEFVDPKVALA
CEEECCCEECC
>Mature Secondary Structure
MIVGVPKEIKNHEYRVGMVPGSVRELTNHGHQVIVETNAGLGIGFSDQDYINVGASIQKN
CCCCCCHHHCCCCEEEEECCCHHHHHHCCCCEEEEECCCCEECCCCCCCCEEECCCHHHH
AAEVFASADMIVKVKEPQAVERAMLREGQILFTYLHLAPDLPQTEDLIKSKAICIAYETV
HHHHHHCCCEEEEECCCHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHCCEEEEEEEEE
TDNQGGLPLLAPMSEVAGRMSIQAGAQALEKSNAGRGMLLGGVPGVAPAKVVIIGGGMVG
ECCCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEEECCEEC
NNAAQMAVGMGAEVVILDRNVNVLRRLDAQFGNKIKTVYSTAEALEEHVLEADLVIGGVL
CCHHHHHCCCCCEEEEEECCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAGAAAPKLVTAEHIKNMKAGSAIVDVAIDQGGCIATSKATTHADPTFIVDDVVHYCVAN
HHCCCCCCEEEHHHHHCCCCCCEEEEEEECCCCEEEECCCCCCCCCCHHHHHHHHHHHHC
MPGAVPLTSTFALNNATLPFIINLANKGYKEALLSDQNFLNGLNVINGKITCASVAENLG
CCCCCCCEEEEEECCCCCEEEEEECCCCHHHHHHCCHHHHCCCEEECCEEEHHHHHHHCC
FEFVDPKVALA
CEEECCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA