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The map label for this gene is fbp

Identifier: 119947157

GI number: 119947157

Start: 4373166

End: 4374179

Strand: Direct

Name: fbp

Synonym: Ping_3555

Alternate gene names: 119947157

Gene position: 4373166-4374179 (Clockwise)

Preceding gene: 119947156

Following gene: 119947159

Centisome position: 95.91

GC content: 40.43

Gene sequence:

>1014_bases
ATGATTACGCTCGGTGAATACATTATTAAAAAGCAGCATGAATCTCCAGAGGCGACAGGAGAATTATCATCTATATTAGG
CGCAATTCGGTTAGCGACCAAAGTTGTTAATAGAGACATAAATAAAGCTGGATTAGTTGATATTATTGGCGCAACGGGTG
TGGAAAATGTGCAGGGTGAAGTCCAGCAAAAAATGGATTTATACGCTAATGACGTTTTTAAAGCGGCATTAGAAGCGCGT
GGTGAAGTTTGTGGTGTGGCATCCGAGGAAGAAGATGAGTTTGTTTCCTTTAATGATCAACGCTGTATAAACAGTAAATA
TGTTGTATTGATGGATCCGCTGGACGGCTCTTCAAATATTGATGTTAATGTATCGGTTGGAACCATTTTCTCCATTTATC
GCCGTATTAGCGAGCCGGGCAAGCCAGCAATCTTAGAAGACTTCCTACAACCAGGAACTGAACAGGTTGCCGCCGGATAT
GTTATATACGGTTCGTCAACTATGTTAGTTTATACAACTGGATATGGTACACACGGCTTTACCTGCGATCCTTCACTGGG
TACTTTTTACCTTTCACATGAAAATATGAAAATTCCAGATAACGGTTCAATTTACTCGATCAATGAAGGTAACTATCTGA
AGTTTCCACAGGGTGTAAAAAAATATTTAAAATACTGTCAAGAAATTGATGGCCCAACAAACCGCCCTTACACATCTCGT
TATATTGGTTCTTTAGTTTCTGATTTTCACCGAAATTTGCTTAAGGGCGGCATTTACATCTACCCTTCTACGGCCTCCGC
ACCAAAAGGTAAGCTAAGATTATTATACGAATGTAACCCGATGGCATTTATAATGGAACAGGCTGGCGGAAGAGCAACCG
ATGGTTTTAACCGCCGCATTATGGAGCTAACACCAACCGAGTTGCACCAGCGAGTGCCATTTTTCTGTGGTAGTTCTAAA
ATGGTCGATAAAGTAGAAGCAATGATGGAAGAGTATTCTTCAGAAGAAAAATAA

Upstream 100 bases:

>100_bases
CAATATTGATGTTAGCTAACATTAATCAATATTAAATCATGTTAATTTTGTACACACGATAACGTTTTGCAGATAATAGA
TCTGGATAAAGGAATATGGA

Downstream 100 bases:

>100_bases
AATCGTTTAACTTTATTCACTTTATACAGATAAAAAAACCGCTCAATGAGCGGTTTTTTTTAATACCAATCCCACTAATT
GGGTGATCTGTTTAGGCGCC

Product: fructose-1,6-bisphosphatase

Products: NA

Alternate protein names: FBPase class 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MITLGEYIIKKQHESPEATGELSSILGAIRLATKVVNRDINKAGLVDIIGATGVENVQGEVQQKMDLYANDVFKAALEAR
GEVCGVASEEEDEFVSFNDQRCINSKYVVLMDPLDGSSNIDVNVSVGTIFSIYRRISEPGKPAILEDFLQPGTEQVAAGY
VIYGSSTMLVYTTGYGTHGFTCDPSLGTFYLSHENMKIPDNGSIYSINEGNYLKFPQGVKKYLKYCQEIDGPTNRPYTSR
YIGSLVSDFHRNLLKGGIYIYPSTASAPKGKLRLLYECNPMAFIMEQAGGRATDGFNRRIMELTPTELHQRVPFFCGSSK
MVDKVEAMMEEYSSEEK

Sequences:

>Translated_337_residues
MITLGEYIIKKQHESPEATGELSSILGAIRLATKVVNRDINKAGLVDIIGATGVENVQGEVQQKMDLYANDVFKAALEAR
GEVCGVASEEEDEFVSFNDQRCINSKYVVLMDPLDGSSNIDVNVSVGTIFSIYRRISEPGKPAILEDFLQPGTEQVAAGY
VIYGSSTMLVYTTGYGTHGFTCDPSLGTFYLSHENMKIPDNGSIYSINEGNYLKFPQGVKKYLKYCQEIDGPTNRPYTSR
YIGSLVSDFHRNLLKGGIYIYPSTASAPKGKLRLLYECNPMAFIMEQAGGRATDGFNRRIMELTPTELHQRVPFFCGSSK
MVDKVEAMMEEYSSEEK
>Mature_337_residues
MITLGEYIIKKQHESPEATGELSSILGAIRLATKVVNRDINKAGLVDIIGATGVENVQGEVQQKMDLYANDVFKAALEAR
GEVCGVASEEEDEFVSFNDQRCINSKYVVLMDPLDGSSNIDVNVSVGTIFSIYRRISEPGKPAILEDFLQPGTEQVAAGY
VIYGSSTMLVYTTGYGTHGFTCDPSLGTFYLSHENMKIPDNGSIYSINEGNYLKFPQGVKKYLKYCQEIDGPTNRPYTSR
YIGSLVSDFHRNLLKGGIYIYPSTASAPKGKLRLLYECNPMAFIMEQAGGRATDGFNRRIMELTPTELHQRVPFFCGSSK
MVDKVEAMMEEYSSEEK

Specific function: INVOLVED IN SEVERAL METABOLIC PATHWAYS. IN E.COLI AND YEAST IT IS NECESSARY FOR GROWTH ON SUBSTANCES SUCH AS GLYCEROL, SUCCINATE AND ACETATE. [C]

COG id: COG0158

COG function: function code G; Fructose-1,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 1 family

Homologues:

Organism=Homo sapiens, GI189083692, Length=335, Percent_Identity=41.1940298507463, Blast_Score=248, Evalue=5e-66,
Organism=Homo sapiens, GI16579888, Length=335, Percent_Identity=41.1940298507463, Blast_Score=248, Evalue=5e-66,
Organism=Homo sapiens, GI22907028, Length=325, Percent_Identity=42.1538461538462, Blast_Score=246, Evalue=3e-65,
Organism=Escherichia coli, GI1790679, Length=332, Percent_Identity=69.2771084337349, Blast_Score=480, Evalue=1e-137,
Organism=Caenorhabditis elegans, GI17508131, Length=333, Percent_Identity=45.6456456456456, Blast_Score=306, Evalue=8e-84,
Organism=Saccharomyces cerevisiae, GI6323409, Length=325, Percent_Identity=42.7692307692308, Blast_Score=276, Evalue=4e-75,
Organism=Drosophila melanogaster, GI45550998, Length=329, Percent_Identity=43.7689969604863, Blast_Score=278, Evalue=5e-75,
Organism=Drosophila melanogaster, GI19921562, Length=329, Percent_Identity=43.7689969604863, Blast_Score=277, Evalue=8e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): F16PA_PSYIN (A1T0H3)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_944837.1
- ProteinModelPortal:   A1T0H3
- SMR:   A1T0H3
- STRING:   A1T0H3
- GeneID:   4625179
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_3555
- eggNOG:   COG0158
- HOGENOM:   HBG731261
- OMA:   TCLLVSE
- PhylomeDB:   A1T0H3
- ProtClustDB:   PRK09293
- BioCyc:   PING357804:PING_3555-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01855
- InterPro:   IPR000146
- InterPro:   IPR020548
- PANTHER:   PTHR11556
- PRINTS:   PR00115

Pfam domain/function: PF00316 FBPase

EC number: =3.1.3.11

Molecular weight: Translated: 37336; Mature: 37336

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS00124 FBPASE

Important sites: BINDING 208-208 BINDING 241-241 BINDING 271-271

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITLGEYIIKKQHESPEATGELSSILGAIRLATKVVNRDINKAGLVDIIGATGVENVQGE
CCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHH
VQQKMDLYANDVFKAALEARGEVCGVASEEEDEFVSFNDQRCINSKYVVLMDPLDGSSNI
HHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCEECCCCEEEEECCCCCCCCE
DVNVSVGTIFSIYRRISEPGKPAILEDFLQPGTEQVAAGYVIYGSSTMLVYTTGYGTHGF
EEEEEHHHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHCCEEEECCCEEEEEEECCCCCCE
TCDPSLGTFYLSHENMKIPDNGSIYSINEGNYLKFPQGVKKYLKYCQEIDGPTNRPYTSR
EECCCCCEEEEECCCEECCCCCCEEEECCCCEEECCHHHHHHHHHHHHCCCCCCCCHHHH
YIGSLVSDFHRNLLKGGIYIYPSTASAPKGKLRLLYECNPMAFIMEQAGGRATDGFNRRI
HHHHHHHHHHHHHHHCCEEEEECCCCCCCCCEEEEEECCCHHHHHHHCCCCCCCCCCCEE
MELTPTELHQRVPFFCGSSKMVDKVEAMMEEYSSEEK
EECCHHHHHHCCCEEECCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MITLGEYIIKKQHESPEATGELSSILGAIRLATKVVNRDINKAGLVDIIGATGVENVQGE
CCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHH
VQQKMDLYANDVFKAALEARGEVCGVASEEEDEFVSFNDQRCINSKYVVLMDPLDGSSNI
HHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCEECCCCEEEEECCCCCCCCE
DVNVSVGTIFSIYRRISEPGKPAILEDFLQPGTEQVAAGYVIYGSSTMLVYTTGYGTHGF
EEEEEHHHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHCCEEEECCCEEEEEEECCCCCCE
TCDPSLGTFYLSHENMKIPDNGSIYSINEGNYLKFPQGVKKYLKYCQEIDGPTNRPYTSR
EECCCCCEEEEECCCEECCCCCCEEEECCCCEEECCHHHHHHHHHHHHCCCCCCCCHHHH
YIGSLVSDFHRNLLKGGIYIYPSTASAPKGKLRLLYECNPMAFIMEQAGGRATDGFNRRI
HHHHHHHHHHHHHHHCCEEEEECCCCCCCCCEEEEEECCCHHHHHHHCCCCCCCCCCCEE
MELTPTELHQRVPFFCGSSKMVDKVEAMMEEYSSEEK
EECCHHHHHHCCCEEECCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA