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The map label for this gene is yhcW [H]

Identifier: 119947130

GI number: 119947130

Start: 4346685

End: 4347353

Strand: Direct

Name: yhcW [H]

Synonym: Ping_3528

Alternate gene names: 119947130

Gene position: 4346685-4347353 (Clockwise)

Preceding gene: 119947129

Following gene: 119947132

Centisome position: 95.33

GC content: 44.39

Gene sequence:

>669_bases
ATGAATTATCAAGCAGCAGTTTTTGATATGGACGGTTTATTATTGGATACCGAAAGAGTATGCCAAAAGGCATTTCAGGA
TGCCTGCCGTCACTTGTCGTTACCCATATTAAATGAGACTTATTTAAAAATAATCGGCACTAACGCCTTAAGTATCAAAA
AGATTATTACCGCAGGTTATGGCCCTGAGCTTGATTATGAGAGTTTGCGCGTTGAGTGGATGAAACGTTACCATGCGGTG
GTTGATTTCCAGGCCATTCCCGTTAAGGAGGGGGTCATTGCTTTACTCGACTGGTTACAAGAGCAGTCCATTCCGATGGC
GGTTGCCACCTCAAGCGAGAAGGACGTCGCATTAACTAAATTAAAATTATCTGGGTTAGAGGGGTATTTTCAGCAGTTAA
GCACCGGATGTGAAGTCACTCACAGTAAACCTCACCCGGAGATATTTTTACTGGCGGCAAAACGCTTAAATACCGATCCC
ACGGCTTGTTTGGCTTTTGAAGACTCAAATCATGGTGTTCGGGCAGCCGTGAATGCTGGCATGCATGTTTTTCAGGTGCC
GGATCTGGTTACTCCCTGCCCAGAAACGCTGGCTTTAGGGCATCAAGTTAAGCCTTCATTAAGTGATGTTTTGTCCCGTC
TGCAAAATGCTCAGCAAGAAAATCAATAA

Upstream 100 bases:

>100_bases
CACTAGGAAAAAAGATGAACTATCAAGCAGCAGTCTTTGACCGGGAACCGTTTATATTGTCATTCCAACTGCTTAAACTA
ATCAATCACTAGGAAAAAAG

Downstream 100 bases:

>100_bases
GCAAACGAATTTTTGGGGATAAATAACGATTTTGCGGGTAAACCGCCCATATCCCCTCCTCAGCAACCCGGACATTGTTT
AATAAAGAAATTAATTTGCC

Product: HAD family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MNYQAAVFDMDGLLLDTERVCQKAFQDACRHLSLPILNETYLKIIGTNALSIKKIITAGYGPELDYESLRVEWMKRYHAV
VDFQAIPVKEGVIALLDWLQEQSIPMAVATSSEKDVALTKLKLSGLEGYFQQLSTGCEVTHSKPHPEIFLLAAKRLNTDP
TACLAFEDSNHGVRAAVNAGMHVFQVPDLVTPCPETLALGHQVKPSLSDVLSRLQNAQQENQ

Sequences:

>Translated_222_residues
MNYQAAVFDMDGLLLDTERVCQKAFQDACRHLSLPILNETYLKIIGTNALSIKKIITAGYGPELDYESLRVEWMKRYHAV
VDFQAIPVKEGVIALLDWLQEQSIPMAVATSSEKDVALTKLKLSGLEGYFQQLSTGCEVTHSKPHPEIFLLAAKRLNTDP
TACLAFEDSNHGVRAAVNAGMHVFQVPDLVTPCPETLALGHQVKPSLSDVLSRLQNAQQENQ
>Mature_222_residues
MNYQAAVFDMDGLLLDTERVCQKAFQDACRHLSLPILNETYLKIIGTNALSIKKIITAGYGPELDYESLRVEWMKRYHAV
VDFQAIPVKEGVIALLDWLQEQSIPMAVATSSEKDVALTKLKLSGLEGYFQQLSTGCEVTHSKPHPEIFLLAAKRLNTDP
TACLAFEDSNHGVRAAVNAGMHVFQVPDLVTPCPETLALGHQVKPSLSDVLSRLQNAQQENQ

Specific function: Unknown

COG id: COG0637

COG function: function code R; Predicted phosphatase/phosphohexomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Homo sapiens, GI197382691, Length=189, Percent_Identity=36.5079365079365, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI207113149, Length=212, Percent_Identity=32.5471698113208, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI296011030, Length=221, Percent_Identity=31.6742081447964, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI296011028, Length=159, Percent_Identity=33.3333333333333, Blast_Score=68, Evalue=7e-12,
Organism=Escherichia coli, GI1789046, Length=187, Percent_Identity=32.0855614973262, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1788021, Length=197, Percent_Identity=30.4568527918782, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787576, Length=212, Percent_Identity=29.7169811320755, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI87082080, Length=188, Percent_Identity=30.3191489361702, Blast_Score=67, Evalue=6e-13,
Organism=Escherichia coli, GI1790151, Length=189, Percent_Identity=26.984126984127, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17554716, Length=242, Percent_Identity=28.099173553719, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI116008157, Length=190, Percent_Identity=36.3157894736842, Blast_Score=100, Evalue=6e-22,
Organism=Drosophila melanogaster, GI17137324, Length=188, Percent_Identity=33.5106382978723, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI20129151, Length=201, Percent_Identity=30.8457711442786, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: NA

Molecular weight: Translated: 24577; Mature: 24577

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYQAAVFDMDGLLLDTERVCQKAFQDACRHLSLPILNETYLKIIGTNALSIKKIITAGY
CCCCEEEEECCCEEECHHHHHHHHHHHHHHHCCCCCCCHHEEEEECCCCHHHHHHHHCCC
GPELDYESLRVEWMKRYHAVVDFQAIPVKEGVIALLDWLQEQSIPMAVATSSEKDVALTK
CCCCCHHHHHHHHHHHHHHHHCEEECCHHHHHHHHHHHHHHCCCCEEEECCCCCCEEEHH
LKLSGLEGYFQQLSTGCEVTHSKPHPEIFLLAAKRLNTDPTACLAFEDSNHGVRAAVNAG
HHHHHHHHHHHHHHCCCEECCCCCCCCEEEEEEHHCCCCCCEEEEEECCCCCEEEHHHCC
MHVFQVPDLVTPCPETLALGHQVKPSLSDVLSRLQNAQQENQ
EEEEECCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNYQAAVFDMDGLLLDTERVCQKAFQDACRHLSLPILNETYLKIIGTNALSIKKIITAGY
CCCCEEEEECCCEEECHHHHHHHHHHHHHHHCCCCCCCHHEEEEECCCCHHHHHHHHCCC
GPELDYESLRVEWMKRYHAVVDFQAIPVKEGVIALLDWLQEQSIPMAVATSSEKDVALTK
CCCCCHHHHHHHHHHHHHHHHCEEECCHHHHHHHHHHHHHHCCCCEEEECCCCCCEEEHH
LKLSGLEGYFQQLSTGCEVTHSKPHPEIFLLAAKRLNTDPTACLAFEDSNHGVRAAVNAG
HHHHHHHHHHHHHHCCCEECCCCCCCCEEEEEEHHCCCCCCEEEEEECCCCCEEEHHHCC
MHVFQVPDLVTPCPETLALGHQVKPSLSDVLSRLQNAQQENQ
EEEEECCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]