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The map label for this gene is tolC [H]

Identifier: 119946965

GI number: 119946965

Start: 4151835

End: 4153169

Strand: Direct

Name: tolC [H]

Synonym: Ping_3360

Alternate gene names: 119946965

Gene position: 4151835-4153169 (Clockwise)

Preceding gene: 119946959

Following gene: 119946967

Centisome position: 91.06

GC content: 38.5

Gene sequence:

>1335_bases
ATGGCCATAAAAAAATTTACTCTCGCGGCATTGTTTGCCGTGACTAGCTACAGTTACTCTGTTCAAGCTGATACGTTATT
ACAAGTTTACCAAACCGCCAAAATCAAAGATCCTATTATCCTCAAAAGCAAAGCGCAGTATGATGCCTATTTAGAAAAAG
TAACACAAGCAAATGCCGCATTATTACCACAAATAGGCTTTGGACTGGAAACAAATTATACCAATTACAATAATGATAAT
TTAAGTAATTCAAACGTTGGGGCCAATATTGGATTAAGCCAATCACTTTATAATGGTTCACATTGGCAACAATTAAGCAT
TGCTGAAAAACAAGCAACACAATATGCCAGCATTTATGGTTTAGCTGCGCAGGATTTATTATTTAGAGCCTCAACGGCTT
ACTTTAATGTCTTACGTGCAGATGAAGCGGTAAAATCAATTAAAGCAAATAAACGCGCGGTTGAACGCCAACTTGAACAG
ACTAAACAGCGTTTTGAAGTGGGTTTAATTGCGATCACCGATGTACATGAAGCACAAGCTGCCTACGACAGAACAACAGC
CGATGAAATTATTGCAGAAAATAATCTAGCTAATACTTATTATGCATTGCGCGAATTAACCGGGGAAGATGTCCTCAAGG
TGTCGTATTTAAATACGAACACTTTTAGCGCACAGAAAATTGAAGGTGGTGTGTCTCTCTGGCGCAGCAAAGCATTAGAG
TACAACTTAGCCTTGCATAGCAAACGCATTGTTAAAGAATTGGCTAAAATGCAAATCGATTTAGCCAAAACTGGCCATAA
ACCCACCTTAGATTTAACCGCTGGAGTAGGTTACAAAAACACATCCTATGATAATAGTAGCGTTAGTGATACAGACATTA
GTAACGGCACTATCGGACTAAGCTTAAATGTGCCGATTTACACCGGGGGCAGTATTAACTCACAGGTCAAACAAGCACAA
TATAATTATGTTTATGCCAGTGAAGATTTAGTACAAACATTCCGTAGCACAGAAGCACAGATCAATAGAGGTTATAACAA
TGTTGGCGCATCAATCAGCTCTCTTCGTGCTTATGAACAAACAGTGCTCTCTTCACGCAGTGCCCTGGATGCAACAAAAG
CGGGTTTTGAAGTGGGTACACGTACTATCGTTGATGTATTAGATGCGACACGCGCGTTATACGAATCTGAAAATCTATTA
GCTAATGCACGTTATGACTATATTATCAATATGTTACAGCTTAAACTTTCTGCAGGTACTCTGGCCGAACAAGATATTAT
CGATATTTCTAACAATTTAATTGAAGTCGATCCAACAGTGTTGGAAAAATATTAA

Upstream 100 bases:

>100_bases
TTTTTTATTCCTTAGCAAAACACCTAACCTGGATGTTTTATATTACACTTAATCTGTCACTAAATTTGAAGCAGCTCGCA
CACTCATAGGATTTATTAAC

Downstream 100 bases:

>100_bases
AGGCCGCTCATTTATCTCTAAAATTTGCTTAATGCCATAAACTGAATTTTAAAAATCAAATTTCAAAAAAAATCTAGTCA
AAAAGGGAGACAATCTGCCT

Product: type I secretion outer membrane protein, TolC family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 444; Mature: 443

Protein sequence:

>444_residues
MAIKKFTLAALFAVTSYSYSVQADTLLQVYQTAKIKDPIILKSKAQYDAYLEKVTQANAALLPQIGFGLETNYTNYNNDN
LSNSNVGANIGLSQSLYNGSHWQQLSIAEKQATQYASIYGLAAQDLLFRASTAYFNVLRADEAVKSIKANKRAVERQLEQ
TKQRFEVGLIAITDVHEAQAAYDRTTADEIIAENNLANTYYALRELTGEDVLKVSYLNTNTFSAQKIEGGVSLWRSKALE
YNLALHSKRIVKELAKMQIDLAKTGHKPTLDLTAGVGYKNTSYDNSSVSDTDISNGTIGLSLNVPIYTGGSINSQVKQAQ
YNYVYASEDLVQTFRSTEAQINRGYNNVGASISSLRAYEQTVLSSRSALDATKAGFEVGTRTIVDVLDATRALYESENLL
ANARYDYIINMLQLKLSAGTLAEQDIIDISNNLIEVDPTVLEKY

Sequences:

>Translated_444_residues
MAIKKFTLAALFAVTSYSYSVQADTLLQVYQTAKIKDPIILKSKAQYDAYLEKVTQANAALLPQIGFGLETNYTNYNNDN
LSNSNVGANIGLSQSLYNGSHWQQLSIAEKQATQYASIYGLAAQDLLFRASTAYFNVLRADEAVKSIKANKRAVERQLEQ
TKQRFEVGLIAITDVHEAQAAYDRTTADEIIAENNLANTYYALRELTGEDVLKVSYLNTNTFSAQKIEGGVSLWRSKALE
YNLALHSKRIVKELAKMQIDLAKTGHKPTLDLTAGVGYKNTSYDNSSVSDTDISNGTIGLSLNVPIYTGGSINSQVKQAQ
YNYVYASEDLVQTFRSTEAQINRGYNNVGASISSLRAYEQTVLSSRSALDATKAGFEVGTRTIVDVLDATRALYESENLL
ANARYDYIINMLQLKLSAGTLAEQDIIDISNNLIEVDPTVLEKY
>Mature_443_residues
AIKKFTLAALFAVTSYSYSVQADTLLQVYQTAKIKDPIILKSKAQYDAYLEKVTQANAALLPQIGFGLETNYTNYNNDNL
SNSNVGANIGLSQSLYNGSHWQQLSIAEKQATQYASIYGLAAQDLLFRASTAYFNVLRADEAVKSIKANKRAVERQLEQT
KQRFEVGLIAITDVHEAQAAYDRTTADEIIAENNLANTYYALRELTGEDVLKVSYLNTNTFSAQKIEGGVSLWRSKALEY
NLALHSKRIVKELAKMQIDLAKTGHKPTLDLTAGVGYKNTSYDNSSVSDTDISNGTIGLSLNVPIYTGGSINSQVKQAQY
NYVYASEDLVQTFRSTEAQINRGYNNVGASISSLRAYEQTVLSSRSALDATKAGFEVGTRTIVDVLDATRALYESENLLA
NARYDYIINMLQLKLSAGTLAEQDIIDISNNLIEVDPTVLEKY

Specific function: May be specialized for signal sequence independent, extracellular secretion in Gram-negative bacteria [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI87082199, Length=422, Percent_Identity=45.4976303317536, Blast_Score=343, Evalue=1e-95,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 240 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010130 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 48972; Mature: 48841

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIKKFTLAALFAVTSYSYSVQADTLLQVYQTAKIKDPIILKSKAQYDAYLEKVTQANAA
CCCHHHHHHHHHHHHHCCCEECHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHCCHH
LLPQIGFGLETNYTNYNNDNLSNSNVGANIGLSQSLYNGSHWQQLSIAEKQATQYASIYG
HCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHH
LAAQDLLFRASTAYFNVLRADEAVKSIKANKRAVERQLEQTKQRFEVGLIAITDVHEAQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCHHHHH
AYDRTTADEIIAENNLANTYYALRELTGEDVLKVSYLNTNTFSAQKIEGGVSLWRSKALE
HHCCCCHHHHHHCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHH
YNLALHSKRIVKELAKMQIDLAKTGHKPTLDLTAGVGYKNTSYDNSSVSDTDISNGTIGL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEEE
SLNVPIYTGGSINSQVKQAQYNYVYASEDLVQTFRSTEAQINRGYNNVGASISSLRAYEQ
EEECEEEECCCCHHHHHHHHCCEEEECHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHH
TVLSSRSALDATKAGFEVGTRTIVDVLDATRALYESENLLANARYDYIINMLQLKLSAGT
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHCCCCC
LAEQDIIDISNNLIEVDPTVLEKY
CCHHHHHHHCCCEEEECHHHHCCC
>Mature Secondary Structure 
AIKKFTLAALFAVTSYSYSVQADTLLQVYQTAKIKDPIILKSKAQYDAYLEKVTQANAA
CCHHHHHHHHHHHHHCCCEECHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHCCHH
LLPQIGFGLETNYTNYNNDNLSNSNVGANIGLSQSLYNGSHWQQLSIAEKQATQYASIYG
HCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHH
LAAQDLLFRASTAYFNVLRADEAVKSIKANKRAVERQLEQTKQRFEVGLIAITDVHEAQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCHHHHH
AYDRTTADEIIAENNLANTYYALRELTGEDVLKVSYLNTNTFSAQKIEGGVSLWRSKALE
HHCCCCHHHHHHCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHH
YNLALHSKRIVKELAKMQIDLAKTGHKPTLDLTAGVGYKNTSYDNSSVSDTDISNGTIGL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEEE
SLNVPIYTGGSINSQVKQAQYNYVYASEDLVQTFRSTEAQINRGYNNVGASISSLRAYEQ
EEECEEEECCCCHHHHHHHHCCEEEECHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHH
TVLSSRSALDATKAGFEVGTRTIVDVLDATRALYESENLLANARYDYIINMLQLKLSAGT
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHCCCCC
LAEQDIIDISNNLIEVDPTVLEKY
CCHHHHHHHCCCEEEECHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]