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The map label for this gene is aaeR [H]

Identifier: 119946957

GI number: 119946957

Start: 4141062

End: 4141982

Strand: Direct

Name: aaeR [H]

Synonym: Ping_3351

Alternate gene names: 119946957

Gene position: 4141062-4141982 (Clockwise)

Preceding gene: 119946952

Following gene: 119946959

Centisome position: 90.82

GC content: 43.76

Gene sequence:

>921_bases
ATGGATATTTCATTTGAGCAACTCAAAAGTATGATTGTCTTTGCCCGGGTAGTAGAGCAGGGCAGTTTAAGCGCCGCGGC
CAAACATATTGGTTTATCACGTGCCGTGGTGAGTTATCACATTAAAAAGCTCGAAACCCATTTAGCCATTAAACTGCTTA
ATCGCTCCACGCGATCTATTACCTTAACGGAGGCGGGTTCACAATATTACCAACGCTGCAGGGTTATTGCCGAACAGGCT
TCAGCTGCCCACCAGCAGATTGAAAATTTAAAAAATGAACCTGAAGGTCTGTTAAAAATAACCTGTCCGGTCAATCTGGG
TCTGCAAATCATCGTCCCGGCATTAAATGCTTTTCGAAAGCTTTACCCTAAAATCGATCTGGATCTGAAACTCACCGATG
AAGTGGTTAATGTTATTAAGGAGGGAATCGATCTTGCCGTTCGTGGCGCACCCTTACCAGATTCCGGTTTGCAGGCCAGT
AAACTCTTCAGTCTAAGCACCTGTTTATGCGGCGCCCCCGCGTATTTTAAAAAGCATGGTTATCCAACCTCCCCTGCTCA
GTTAACTGCCCATGAGTGGGTTATTTACAAACTCACATCCAGTACGATCGAGTTAAGCAAAGGTAATAGATCCTTTAGTA
TTAAAGTCAAAGGGGGGATCAGTACTAATAATGCAGCAGCGCGCACCGCTTTTGTTGAAGGTGGCCATGGGTTAGGCCGT
ATTCCAACTTATGATGCCTGGCCAAAAATACAGGCAGGCACCTTGGAATCAATTCTTGGTGAATACCAGCTTAATGATAT
TGATCTTTATGGGGTATTTCCATCCGGTGGAGCAGAATCTAAAAAACTGCGCTTATTAATTGATTATTTGAAAACTTTTT
TCGGTCAGTACAAGGATCTGGCTCAGGGTCTTAAATTGTAA

Upstream 100 bases:

>100_bases
AGTGTATGCCGGTATAGGAATTTTAACAATGCAGACATAACTGACATCATTGTTACAATAATTGATACAATAGATAAATA
TTTAGCTATAGAGAGAAATA

Downstream 100 bases:

>100_bases
AGGGTGACTTATAATAAATCCGATGCTCTTATCATTTATTATTTATTATTTGAAAAACAGTTTCAGCTATCTTTGCTTTT
ATCATCTATAACATTGTTAC

Product: transcriptional regulator, substrate-binding, LysR family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MDISFEQLKSMIVFARVVEQGSLSAAAKHIGLSRAVVSYHIKKLETHLAIKLLNRSTRSITLTEAGSQYYQRCRVIAEQA
SAAHQQIENLKNEPEGLLKITCPVNLGLQIIVPALNAFRKLYPKIDLDLKLTDEVVNVIKEGIDLAVRGAPLPDSGLQAS
KLFSLSTCLCGAPAYFKKHGYPTSPAQLTAHEWVIYKLTSSTIELSKGNRSFSIKVKGGISTNNAAARTAFVEGGHGLGR
IPTYDAWPKIQAGTLESILGEYQLNDIDLYGVFPSGGAESKKLRLLIDYLKTFFGQYKDLAQGLKL

Sequences:

>Translated_306_residues
MDISFEQLKSMIVFARVVEQGSLSAAAKHIGLSRAVVSYHIKKLETHLAIKLLNRSTRSITLTEAGSQYYQRCRVIAEQA
SAAHQQIENLKNEPEGLLKITCPVNLGLQIIVPALNAFRKLYPKIDLDLKLTDEVVNVIKEGIDLAVRGAPLPDSGLQAS
KLFSLSTCLCGAPAYFKKHGYPTSPAQLTAHEWVIYKLTSSTIELSKGNRSFSIKVKGGISTNNAAARTAFVEGGHGLGR
IPTYDAWPKIQAGTLESILGEYQLNDIDLYGVFPSGGAESKKLRLLIDYLKTFFGQYKDLAQGLKL
>Mature_306_residues
MDISFEQLKSMIVFARVVEQGSLSAAAKHIGLSRAVVSYHIKKLETHLAIKLLNRSTRSITLTEAGSQYYQRCRVIAEQA
SAAHQQIENLKNEPEGLLKITCPVNLGLQIIVPALNAFRKLYPKIDLDLKLTDEVVNVIKEGIDLAVRGAPLPDSGLQAS
KLFSLSTCLCGAPAYFKKHGYPTSPAQLTAHEWVIYKLTSSTIELSKGNRSFSIKVKGGISTNNAAARTAFVEGGHGLGR
IPTYDAWPKIQAGTLESILGEYQLNDIDLYGVFPSGGAESKKLRLLIDYLKTFFGQYKDLAQGLKL

Specific function: Activates transcription of the aaeXAB operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=302, Percent_Identity=31.7880794701987, Blast_Score=165, Evalue=4e-42,
Organism=Escherichia coli, GI1786401, Length=287, Percent_Identity=31.0104529616725, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI1789440, Length=292, Percent_Identity=30.4794520547945, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI145693193, Length=299, Percent_Identity=28.7625418060201, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI87081978, Length=293, Percent_Identity=28.6689419795222, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1787128, Length=286, Percent_Identity=27.6223776223776, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1787589, Length=291, Percent_Identity=26.1168384879725, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1788706, Length=294, Percent_Identity=24.4897959183673, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789173, Length=184, Percent_Identity=26.0869565217391, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1788481, Length=293, Percent_Identity=24.5733788395904, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1788748, Length=167, Percent_Identity=28.1437125748503, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790262, Length=233, Percent_Identity=26.1802575107296, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1787601, Length=128, Percent_Identity=26.5625, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1786508, Length=217, Percent_Identity=26.2672811059908, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI145693105, Length=250, Percent_Identity=22.4, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33507; Mature: 33507

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDISFEQLKSMIVFARVVEQGSLSAAAKHIGLSRAVVSYHIKKLETHLAIKLLNRSTRSI
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
TLTEAGSQYYQRCRVIAEQASAAHQQIENLKNEPEGLLKITCPVNLGLQIIVPALNAFRK
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHH
LYPKIDLDLKLTDEVVNVIKEGIDLAVRGAPLPDSGLQASKLFSLSTCLCGAPAYFKKHG
HCCCCCCCEEEHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCHHHHHCC
YPTSPAQLTAHEWVIYKLTSSTIELSKGNRSFSIKVKGGISTNNAAARTAFVEGGHGLGR
CCCCCCCEECCEEEEEEEECCEEEEECCCEEEEEEEECCCCCCCCHHHEEEEECCCCCCC
IPTYDAWPKIQAGTLESILGEYQLNDIDLYGVFPSGGAESKKLRLLIDYLKTFFGQYKDL
CCCCCCCCCCCCCCHHHHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHH
AQGLKL
HHHCCC
>Mature Secondary Structure
MDISFEQLKSMIVFARVVEQGSLSAAAKHIGLSRAVVSYHIKKLETHLAIKLLNRSTRSI
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
TLTEAGSQYYQRCRVIAEQASAAHQQIENLKNEPEGLLKITCPVNLGLQIIVPALNAFRK
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHH
LYPKIDLDLKLTDEVVNVIKEGIDLAVRGAPLPDSGLQASKLFSLSTCLCGAPAYFKKHG
HCCCCCCCEEEHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCHHHHHCC
YPTSPAQLTAHEWVIYKLTSSTIELSKGNRSFSIKVKGGISTNNAAARTAFVEGGHGLGR
CCCCCCCEECCEEEEEEEECCEEEEECCCEEEEEEEECCCCCCCCHHHEEEEECCCCCCC
IPTYDAWPKIQAGTLESILGEYQLNDIDLYGVFPSGGAESKKLRLLIDYLKTFFGQYKDL
CCCCCCCCCCCCCCHHHHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHH
AQGLKL
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]