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The map label for this gene is fecD [H]

Identifier: 119946948

GI number: 119946948

Start: 4131597

End: 4132634

Strand: Direct

Name: fecD [H]

Synonym: Ping_3342

Alternate gene names: 119946948

Gene position: 4131597-4132634 (Clockwise)

Preceding gene: 119946947

Following gene: 119946949

Centisome position: 90.61

GC content: 46.05

Gene sequence:

>1038_bases
ATGTTCACTAATTTAACCACCATCCGCTTAGTATTATTACTGTTAATGCTGCTGGTTATCGCTCTGACTGTCTTAGGGGT
GTTACAAGGCCCTGCTGATATTTCATTAAGTCATATTGGTACTATCTTCAAACAGGCTCTGTTTACTGCGCCAGGCAGTG
ATATTGCCAACTGGCAGCACAGCGTTATTATGGATATTCGTTTACCGCGCGTTATTATTGCCCTGTTTGCCGGTGCAAGT
TTAGCGTTATGCGGACTGGTCATGCAGGGAATGTTCCGTAATCCTCTGGCCTCCCCTTCCGTATTAGGTGTTTCATCGGG
TGCCTCATTAGGCGCTGTGATCGCTATTTATCTTGGTTTTTCCCTTATTTCCGCCTGGGCCATTCCACTGTTTGCTTTTA
TTGGTGCCGGAGTCTCGTTAAGCATTGTTTACCGCGTGGCCTCCAGCAGAGGACAAACGAATATCGCTACCCTGCTGCTT
TCAGGCGTTGCCATCAGCGCACTTAATGTCGCCGCCACCTCATTATTACTGGCTTTATCCCTGAGTAATTGGGATGTCGC
ACGAATGATTATTTATTGGACCATGGGCGGACTTGATGGGCGCACCTGGGATCATGTGCTTATTATTCTGCCGATTGTCC
TGAGCGGATTTGTATTACTGCTATTTTATAGCAAACAATTAGATCTATTATTGTTAGGTGAGCAGCATGCTCTCTCGGTC
GGTGTTGATGTACGCAAAACGCGCCTCAATCTTTTAATTATCAGCAGCGCGATGGTGGGAGCATCGGTTTCAGTGGTCGG
CGGAATCGGCTTTATCGGCTTGGTTGTACCGCATATTTTACGTTTATTATTAGGCCCCGCACACCGTTATCTGTTACCCG
CCTGTTTATTTGGCGGAGCAATTACGCTGCTTGGCGCAGATCTGTTTTTAAACAGTTTTTTTAGTGAGCAGGCTATTCCA
CTGGGTGTGGTGACGGCTGCGTTAGGAGCACCTTTCTTTCTATTTCTTTTAATCAAACAACGTTTTGTTTTAAGTTAG

Upstream 100 bases:

>100_bases
GGTACCTGGCTCAGAAGTGTTTCCCAGCACCGGATCAAAGGTGTTGAAGCAATAGCTCAACTGCTGCATCCAGCAATAGA
AAGTTACCCTGAGAAAATCA

Downstream 100 bases:

>100_bases
TGGAGCCTTATTTATGTCGCCTTTAAGTTGTACCAAGCTCGCTTTCTCCTATGATAAAAAACCGTTATTAACGGATATTA
ATTTAGACTTTAAAACCGGC

Product: iron(III) dicitrate transport system permease protein FecD

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MFTNLTTIRLVLLLLMLLVIALTVLGVLQGPADISLSHIGTIFKQALFTAPGSDIANWQHSVIMDIRLPRVIIALFAGAS
LALCGLVMQGMFRNPLASPSVLGVSSGASLGAVIAIYLGFSLISAWAIPLFAFIGAGVSLSIVYRVASSRGQTNIATLLL
SGVAISALNVAATSLLLALSLSNWDVARMIIYWTMGGLDGRTWDHVLIILPIVLSGFVLLLFYSKQLDLLLLGEQHALSV
GVDVRKTRLNLLIISSAMVGASVSVVGGIGFIGLVVPHILRLLLGPAHRYLLPACLFGGAITLLGADLFLNSFFSEQAIP
LGVVTAALGAPFFLFLLIKQRFVLS

Sequences:

>Translated_345_residues
MFTNLTTIRLVLLLLMLLVIALTVLGVLQGPADISLSHIGTIFKQALFTAPGSDIANWQHSVIMDIRLPRVIIALFAGAS
LALCGLVMQGMFRNPLASPSVLGVSSGASLGAVIAIYLGFSLISAWAIPLFAFIGAGVSLSIVYRVASSRGQTNIATLLL
SGVAISALNVAATSLLLALSLSNWDVARMIIYWTMGGLDGRTWDHVLIILPIVLSGFVLLLFYSKQLDLLLLGEQHALSV
GVDVRKTRLNLLIISSAMVGASVSVVGGIGFIGLVVPHILRLLLGPAHRYLLPACLFGGAITLLGADLFLNSFFSEQAIP
LGVVTAALGAPFFLFLLIKQRFVLS
>Mature_345_residues
MFTNLTTIRLVLLLLMLLVIALTVLGVLQGPADISLSHIGTIFKQALFTAPGSDIANWQHSVIMDIRLPRVIIALFAGAS
LALCGLVMQGMFRNPLASPSVLGVSSGASLGAVIAIYLGFSLISAWAIPLFAFIGAGVSLSIVYRVASSRGQTNIATLLL
SGVAISALNVAATSLLLALSLSNWDVARMIIYWTMGGLDGRTWDHVLIILPIVLSGFVLLLFYSKQLDLLLLGEQHALSV
GVDVRKTRLNLLIISSAMVGASVSVVGGIGFIGLVVPHILRLLLGPAHRYLLPACLFGGAITLLGADLFLNSFFSEQAIP
LGVVTAALGAPFFLFLLIKQRFVLS

Specific function: Part of the binding-protein-dependent transport system for hemin; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=292, Percent_Identity=39.7260273972603, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI1788004, Length=295, Percent_Identity=39.6610169491525, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1790741, Length=282, Percent_Identity=34.7517730496454, Blast_Score=128, Evalue=6e-31,
Organism=Escherichia coli, GI1786805, Length=282, Percent_Identity=36.1702127659575, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1786804, Length=334, Percent_Identity=32.9341317365269, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1786347, Length=302, Percent_Identity=31.4569536423841, Blast_Score=107, Evalue=9e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 36484; Mature: 36484

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTNLTTIRLVLLLLMLLVIALTVLGVLQGPADISLSHIGTIFKQALFTAPGSDIANWQH
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCHHCCCCH
SVIMDIRLPRVIIALFAGASLALCGLVMQGMFRNPLASPSVLGVSSGASLGAVIAIYLGF
HHEEEHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHHH
SLISAWAIPLFAFIGAGVSLSIVYRVASSRGQTNIATLLLSGVAISALNVAATSLLLALS
HHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSNWDVARMIIYWTMGGLDGRTWDHVLIILPIVLSGFVLLLFYSKQLDLLLLGEQHALSV
CCCCHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHEEE
GVDVRKTRLNLLIISSAMVGASVSVVGGIGFIGLVVPHILRLLLGPAHRYLLPACLFGGA
CCCHHHHHEEEEEEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
ITLLGADLFLNSFFSEQAIPLGVVTAALGAPFFLFLLIKQRFVLS
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFTNLTTIRLVLLLLMLLVIALTVLGVLQGPADISLSHIGTIFKQALFTAPGSDIANWQH
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCHHCCCCH
SVIMDIRLPRVIIALFAGASLALCGLVMQGMFRNPLASPSVLGVSSGASLGAVIAIYLGF
HHEEEHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHHH
SLISAWAIPLFAFIGAGVSLSIVYRVASSRGQTNIATLLLSGVAISALNVAATSLLLALS
HHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSNWDVARMIIYWTMGGLDGRTWDHVLIILPIVLSGFVLLLFYSKQLDLLLLGEQHALSV
CCCCHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHEEE
GVDVRKTRLNLLIISSAMVGASVSVVGGIGFIGLVVPHILRLLLGPAHRYLLPACLFGGA
CCCHHHHHEEEEEEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
ITLLGADLFLNSFFSEQAIPLGVVTAALGAPFFLFLLIKQRFVLS
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9026634; 11586360; 12142430 [H]