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The map label for this gene is fis

Identifier: 119946822

GI number: 119946822

Start: 3971885

End: 3972184

Strand: Direct

Name: fis

Synonym: Ping_3216

Alternate gene names: 119946822

Gene position: 3971885-3972184 (Clockwise)

Preceding gene: 119946821

Following gene: 119946823

Centisome position: 87.11

GC content: 40.33

Gene sequence:

>300_bases
ATGTTTGAACAAAAGATTTCGTCAGAAGCACTTACAACAACAACTAGTATTCCTGCTACAGGGCAAATAACTCAGCGACC
ACTTCGTGATTCGGTACGCCAAGCAGTGTCGGGTTATGTAGCGCAACTTAATGGTCAAGATCCAACTGAATTATATGAAC
TTGTTTTATCTGAAGTTGAAGCACCATTATTGGATATTATTATGCAGTATACTCGTGGTAATCAAACGCGTGCGGCAACT
ATGCTAGGCATTAACCGTGGTACATTACGCAAGAAACTGAAAAAATATGGCATGGGTTGA

Upstream 100 bases:

>100_bases
CAGTTAGGTCACTTTAAGCGACAATTCAATGCAATTGACTGCCCGTATGAGCAATTAAAAACATTAGAAACTTACTTAAA
TAAATAAAGAGTTAATAGCT

Downstream 100 bases:

>100_bases
TTTCTTCGCCATTATTTAATCGAAAAAGCGACTAAAAAGTCGCTTTTTTTATGCCTCGAATAAAAAGTTATTTGCCACTA
AGCTATCAGCTTGAACCTTT

Product: factor-for-inversion stimulation protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 99; Mature: 99

Protein sequence:

>99_residues
MFEQKISSEALTTTTSIPATGQITQRPLRDSVRQAVSGYVAQLNGQDPTELYELVLSEVEAPLLDIIMQYTRGNQTRAAT
MLGINRGTLRKKLKKYGMG

Sequences:

>Translated_99_residues
MFEQKISSEALTTTTSIPATGQITQRPLRDSVRQAVSGYVAQLNGQDPTELYELVLSEVEAPLLDIIMQYTRGNQTRAAT
MLGINRGTLRKKLKKYGMG
>Mature_99_residues
MFEQKISSEALTTTTSIPATGQITQRPLRDSVRQAVSGYVAQLNGQDPTELYELVLSEVEAPLLDIIMQYTRGNQTRAAT
MLGINRGTLRKKLKKYGMG

Specific function: Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters

COG id: COG2901

COG function: function code KL; Factor for inversion stimulation Fis, transcriptional activator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transcriptional regulatory fis family

Homologues:

Organism=Escherichia coli, GI1789661, Length=99, Percent_Identity=69.6969696969697, Blast_Score=150, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FIS_PSYIN (A1SZI8)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_944502.1
- ProteinModelPortal:   A1SZI8
- SMR:   A1SZI8
- STRING:   A1SZI8
- GeneID:   4624649
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_3216
- eggNOG:   COG2901
- HOGENOM:   HBG509520
- OMA:   EMVLCEV
- PhylomeDB:   A1SZI8
- BioCyc:   PING357804:PING_3216-MONOMER
- HAMAP:   MF_00166
- InterPro:   IPR005412
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- PIRSF:   PIRSF002097
- PRINTS:   PR01591
- PRINTS:   PR01590

Pfam domain/function: PF02954 HTH_8; SSF46689 Homeodomain_like

EC number: NA

Molecular weight: Translated: 10961; Mature: 10961

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFEQKISSEALTTTTSIPATGQITQRPLRDSVRQAVSGYVAQLNGQDPTELYELVLSEVE
CCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHC
APLLDIIMQYTRGNQTRAATMLGINRGTLRKKLKKYGMG
HHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MFEQKISSEALTTTTSIPATGQITQRPLRDSVRQAVSGYVAQLNGQDPTELYELVLSEVE
CCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHC
APLLDIIMQYTRGNQTRAATMLGINRGTLRKKLKKYGMG
HHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA