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The map label for this gene is prmA [H]

Identifier: 119946820

GI number: 119946820

Start: 3969390

End: 3970325

Strand: Direct

Name: prmA [H]

Synonym: Ping_3214

Alternate gene names: 119946820

Gene position: 3969390-3970325 (Clockwise)

Preceding gene: 119946819

Following gene: 119946821

Centisome position: 87.06

GC content: 41.24

Gene sequence:

>936_bases
ATGCTTAGTCTCATTATTATAACCATCTTAAAAAAGGAAAAAATCATGCCTTGGATACAATTAAAGTTAAATGCAACTGC
CAAAAATGCAGAAAACATAGGTGAACTGTTAATGGAAAATGGTGCATTATCGGTCACCTTTACCGATGCACAGGATGTCC
CTATTTTTGAGCCTGCACCAGGTGAAACGCGTCTTTGGGGTAATACAGATATTACCGGTCTTTATGAAGCAGAAACGAAT
ATGTTACCCATACTTGAGCAATTACGTAACAGTCCACTTTTAAGCAGTGATTTTTCCCACAAAATTGAAGCGCTGGAGGA
CAAAGACTGGGAACGTGAATGGATGGATAAATTCCACCCGATGAAATTTGGTCAACGTTTATGGATCTGCCCAAGCTGGA
AGCCCGTACCCGATGAAAACGCTATCAATGTCATGCTTGATCCCGGGCTTGCATTTGGTACAGGTACACACCCCACCACC
GCTTTATGTTTGACCTGGTTAGACAGCCTGGATTTACAAGATAAAGTGGTTATCGATTTTGGTTGTGGCTCCGGAATTTT
AGCCATTGCAGCCTTAAAATTAGGTGCTAAAAGAGTGATTGGTATTGATCTTGATCCCCAGGCAATTACGGCTAGCCGCG
ATAATGCGCAACGTAACAATGTGTCAGATCAACTTGAATTATATTTACCAGCTGATTTACCCGAAGGTATTTTCGCCGAT
GTTTTAGTTGCGAATATTCTTGCAGGCCCGCTTCGTGAACTATCAACAAATATTGAATCCTTAGTAAAAAGCAACGGATC
ACTTGCATTATCAGGTATTCTAGAGCAACAAGCAGATGAATTGATTGAAGTTTACGGACAGTGGTTCACCATGGAGAAAG
CAACGATTAAAGAAGAGTGGGCAAGACTTTCTGGGATCAAAAATATCGCCAGCTAA

Upstream 100 bases:

>100_bases
TGAGATTCTTGCTTAAATCTACAACATCAGCTGTTCTGGATACACTAAAACCGCACTCACATGAATTAACTGCTCAACCT
TCTTCGCAGGGTTAGCGCTT

Downstream 100 bases:

>100_bases
TCTACGGTAAAGGTAATAAAAATAAAGACCAATCAGTAAGGCTATTTGATATCAAAATATCACCAACCTGCTGCAGAGTT
AACAATAACAATCACTAAAT

Product: methyltransferase of 50S ribosomal subunit protein L11

Products: NA

Alternate protein names: L11 Mtase [H]

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MLSLIIITILKKEKIMPWIQLKLNATAKNAENIGELLMENGALSVTFTDAQDVPIFEPAPGETRLWGNTDITGLYEAETN
MLPILEQLRNSPLLSSDFSHKIEALEDKDWEREWMDKFHPMKFGQRLWICPSWKPVPDENAINVMLDPGLAFGTGTHPTT
ALCLTWLDSLDLQDKVVIDFGCGSGILAIAALKLGAKRVIGIDLDPQAITASRDNAQRNNVSDQLELYLPADLPEGIFAD
VLVANILAGPLRELSTNIESLVKSNGSLALSGILEQQADELIEVYGQWFTMEKATIKEEWARLSGIKNIAS

Sequences:

>Translated_311_residues
MLSLIIITILKKEKIMPWIQLKLNATAKNAENIGELLMENGALSVTFTDAQDVPIFEPAPGETRLWGNTDITGLYEAETN
MLPILEQLRNSPLLSSDFSHKIEALEDKDWEREWMDKFHPMKFGQRLWICPSWKPVPDENAINVMLDPGLAFGTGTHPTT
ALCLTWLDSLDLQDKVVIDFGCGSGILAIAALKLGAKRVIGIDLDPQAITASRDNAQRNNVSDQLELYLPADLPEGIFAD
VLVANILAGPLRELSTNIESLVKSNGSLALSGILEQQADELIEVYGQWFTMEKATIKEEWARLSGIKNIAS
>Mature_311_residues
MLSLIIITILKKEKIMPWIQLKLNATAKNAENIGELLMENGALSVTFTDAQDVPIFEPAPGETRLWGNTDITGLYEAETN
MLPILEQLRNSPLLSSDFSHKIEALEDKDWEREWMDKFHPMKFGQRLWICPSWKPVPDENAINVMLDPGLAFGTGTHPTT
ALCLTWLDSLDLQDKVVIDFGCGSGILAIAALKLGAKRVIGIDLDPQAITASRDNAQRNNVSDQLELYLPADLPEGIFAD
VLVANILAGPLRELSTNIESLVKSNGSLALSGILEQQADELIEVYGQWFTMEKATIKEEWARLSGIKNIAS

Specific function: Methylates ribosomal protein L11 [H]

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family [H]

Homologues:

Organism=Escherichia coli, GI2367208, Length=293, Percent_Identity=68.6006825938567, Blast_Score=390, Evalue=1e-110,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010456
- InterPro:   IPR004498 [H]

Pfam domain/function: PF06325 PrmA [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 34397; Mature: 34397

Theoretical pI: Translated: 4.31; Mature: 4.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSLIIITILKKEKIMPWIQLKLNATAKNAENIGELLMENGALSVTFTDAQDVPIFEPAP
CHHEEEEEEHHHHHCCCEEEEEEECCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCC
GETRLWGNTDITGLYEAETNMLPILEQLRNSPLLSSDFSHKIEALEDKDWEREWMDKFHP
CCCEECCCCCCCEEEECCCCHHHHHHHHCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHCC
MKFGQRLWICPSWKPVPDENAINVMLDPGLAFGTGTHPTTALCLTWLDSLDLQDKVVIDF
HHHCCEEEECCCCCCCCCCCCEEEEECCCEEECCCCCHHHHHHHHHHHCCCCCCEEEEEE
GCGSGILAIAALKLGAKRVIGIDLDPQAITASRDNAQRNNVSDQLELYLPADLPEGIFAD
CCCCHHHHHHHHHHCCCEEEEECCCCCCEECCCCCCHHCCCCCEEEEEECCCCCCHHHHH
VLVANILAGPLRELSTNIESLVKSNGSLALSGILEQQADELIEVYGQWFTMEKATIKEEW
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHEEHHHHHHHHH
ARLSGIKNIAS
HHHHHHHHHCC
>Mature Secondary Structure
MLSLIIITILKKEKIMPWIQLKLNATAKNAENIGELLMENGALSVTFTDAQDVPIFEPAP
CHHEEEEEEHHHHHCCCEEEEEEECCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCC
GETRLWGNTDITGLYEAETNMLPILEQLRNSPLLSSDFSHKIEALEDKDWEREWMDKFHP
CCCEECCCCCCCEEEECCCCHHHHHHHHCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHCC
MKFGQRLWICPSWKPVPDENAINVMLDPGLAFGTGTHPTTALCLTWLDSLDLQDKVVIDF
HHHCCEEEECCCCCCCCCCCCEEEEECCCEEECCCCCHHHHHHHHHHHCCCCCCEEEEEE
GCGSGILAIAALKLGAKRVIGIDLDPQAITASRDNAQRNNVSDQLELYLPADLPEGIFAD
CCCCHHHHHHHHHHCCCEEEEECCCCCCEECCCCCCHHCCCCCEEEEEECCCCCCHHHHH
VLVANILAGPLRELSTNIESLVKSNGSLALSGILEQQADELIEVYGQWFTMEKATIKEEW
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHEEHHHHHHHHH
ARLSGIKNIAS
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA