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The map label for this gene is tsf

Identifier: 119946596

GI number: 119946596

Start: 3667808

End: 3668686

Strand: Reverse

Name: tsf

Synonym: Ping_2975

Alternate gene names: 119946596

Gene position: 3668686-3667808 (Counterclockwise)

Preceding gene: 119946597

Following gene: 119946595

Centisome position: 80.46

GC content: 40.84

Gene sequence:

>879_bases
ATGGCTATTACTGTAACAGCTAAGCAAGTTAAAGAACTTCGTGACCGTACTGCTGCGGGTATGATGGATTGTAAAAAAGC
ATTAGTTGAAGCTGAGGGCGACCTTGAGCTTGCAATTGAAAACATGCGTAAATCAGGTGCAGTTAAAGCCGCTAAAAAAG
CTGGCCGAGTTGCTGCTGAAGGTGTGATTTTAGCAAAAGTTGAGGGTAGTGTTGCCCTTCTTGCTGAAGTAAACTGTGAA
ACAGATTTTGTAGCAATGGATAAAAGCTTTCTTGCTTTTGCAAATAAAATTGCAGAAATCGCATTAGCCAATAAAGTGGC
TAGCGTGGAAGCTCTCAATGAATTAGCTTACGATGGTGATACTGTAGAAGTTGCTCGTGCTAATTTAGTGTCTAAAATTG
GTGAAAATATCTCTATTCGTCGTTTACATATCGTTGAAGGTGAAAACCTTGGTGCTTATGTACACAGTGGCAAAATTGGT
GTTATCTCTGTGCTTAAAGGTGGTGATGCAGATCTTTCTAAAGATATCGCAATGCACGTTGCTGCAGCTGCTCCTCAGTA
TGTTAAAGCTGAAGATGTACCTGCTGATGTTGTTGCTAAAGAGAAAGAGATTCAGCTTGCAATCGCAGTAGAAAGTGGTA
AACCTGAAGCTATTGCTGAAAAAATGGTTGCTGGCCGTATGGCTAAATTTTCTGGTGAAGTTAGCCTGACAAGTCAACCC
TTCATTAAAGATCCTTCTATCAAAGTTGCTAAGCTTCTTAAAGACGCTGGCGCTGAGGTTATCTCATTTATTCGTTTAGA
AGTGGGTGAAGGCATCGATAAGAAAGTTGAAGATTTTGCTGCTGAAGTTGCTGCGACAATGGCTGCTTCTGCTAAGTAA

Upstream 100 bases:

>100_bases
TTAGCCTTTTTGAGCTAAATATCTCTTATTAATCAGTCTATGATTGATTATTGGGGGGCTATTGCCCCCCCTTTTTAATT
GAAATAATAGGAATTCGACA

Downstream 100 bases:

>100_bases
TCAATTTCTCTAAATAAGACGCTTTGTTTATTGTCTTTGAAGAACCGCAGCTACGTCTGCGGTTCTTTTGCATTCAAAAT
AGGGTTTAATATTGTCTTTA

Product: translation elongation factor Ts

Products: NA

Alternate protein names: EF-Ts

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MAITVTAKQVKELRDRTAAGMMDCKKALVEAEGDLELAIENMRKSGAVKAAKKAGRVAAEGVILAKVEGSVALLAEVNCE
TDFVAMDKSFLAFANKIAEIALANKVASVEALNELAYDGDTVEVARANLVSKIGENISIRRLHIVEGENLGAYVHSGKIG
VISVLKGGDADLSKDIAMHVAAAAPQYVKAEDVPADVVAKEKEIQLAIAVESGKPEAIAEKMVAGRMAKFSGEVSLTSQP
FIKDPSIKVAKLLKDAGAEVISFIRLEVGEGIDKKVEDFAAEVAATMAASAK

Sequences:

>Translated_292_residues
MAITVTAKQVKELRDRTAAGMMDCKKALVEAEGDLELAIENMRKSGAVKAAKKAGRVAAEGVILAKVEGSVALLAEVNCE
TDFVAMDKSFLAFANKIAEIALANKVASVEALNELAYDGDTVEVARANLVSKIGENISIRRLHIVEGENLGAYVHSGKIG
VISVLKGGDADLSKDIAMHVAAAAPQYVKAEDVPADVVAKEKEIQLAIAVESGKPEAIAEKMVAGRMAKFSGEVSLTSQP
FIKDPSIKVAKLLKDAGAEVISFIRLEVGEGIDKKVEDFAAEVAATMAASAK
>Mature_291_residues
AITVTAKQVKELRDRTAAGMMDCKKALVEAEGDLELAIENMRKSGAVKAAKKAGRVAAEGVILAKVEGSVALLAEVNCET
DFVAMDKSFLAFANKIAEIALANKVASVEALNELAYDGDTVEVARANLVSKIGENISIRRLHIVEGENLGAYVHSGKIGV
ISVLKGGDADLSKDIAMHVAAAAPQYVKAEDVPADVVAKEKEIQLAIAVESGKPEAIAEKMVAGRMAKFSGEVSLTSQPF
IKDPSIKVAKLLKDAGAEVISFIRLEVGEGIDKKVEDFAAEVAATMAASAK

Specific function: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome

COG id: COG0264

COG function: function code J; Translation elongation factor Ts

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EF-Ts family

Homologues:

Organism=Homo sapiens, GI171846268, Length=296, Percent_Identity=26.0135135135135, Blast_Score=85, Evalue=7e-17,
Organism=Escherichia coli, GI1786366, Length=281, Percent_Identity=60.4982206405694, Blast_Score=329, Evalue=1e-91,
Organism=Caenorhabditis elegans, GI17561440, Length=292, Percent_Identity=26.3698630136986, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI19921466, Length=303, Percent_Identity=25.4125412541254, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: 2670 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1100 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 4173 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 14563 Molecules/Cell In: Growth Phase, Gluco

Swissprot (AC and ID): EFTS_PSYIN (A1SYW2)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_944276.1
- ProteinModelPortal:   A1SYW2
- SMR:   A1SYW2
- STRING:   A1SYW2
- GeneID:   4624779
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_2975
- eggNOG:   COG0264
- HOGENOM:   HBG713289
- OMA:   YLHGTRI
- PhylomeDB:   A1SYW2
- BioCyc:   PING357804:PING_2975-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00050
- InterPro:   IPR001816
- InterPro:   IPR014039
- InterPro:   IPR009060
- InterPro:   IPR000449
- Gene3D:   G3DSA:3.30.479.20
- PANTHER:   PTHR11741
- TIGRFAMs:   TIGR00116

Pfam domain/function: PF00889 EF_TS; PF00627 UBA; SSF54713 EF_TS; SSF46934 UBA_like

EC number: NA

Molecular weight: Translated: 30648; Mature: 30517

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS01126 EF_TS_1; PS01127 EF_TS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAITVTAKQVKELRDRTAAGMMDCKKALVEAEGDLELAIENMRKSGAVKAAKKAGRVAAE
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHCCCHHHC
GVILAKVEGSVALLAEVNCETDFVAMDKSFLAFANKIAEIALANKVASVEALNELAYDGD
CEEEEEECCCEEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
TVEVARANLVSKIGENISIRRLHIVEGENLGAYVHSGKIGVISVLKGGDADLSKDIAMHV
HHHHHHHHHHHHHCCCCEEEEEEEEECCCCCEEEECCCEEEEEEECCCCCCHHHHHHHHH
AAAAPQYVKAEDVPADVVAKEKEIQLAIAVESGKPEAIAEKMVAGRMAKFSGEVSLTSQP
HHCCCCCEECCCCCHHHHCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHCCCCEEECCCC
FIKDPSIKVAKLLKDAGAEVISFIRLEVGEGIDKKVEDFAAEVAATMAASAK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AITVTAKQVKELRDRTAAGMMDCKKALVEAEGDLELAIENMRKSGAVKAAKKAGRVAAE
EEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHCCCHHHC
GVILAKVEGSVALLAEVNCETDFVAMDKSFLAFANKIAEIALANKVASVEALNELAYDGD
CEEEEEECCCEEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
TVEVARANLVSKIGENISIRRLHIVEGENLGAYVHSGKIGVISVLKGGDADLSKDIAMHV
HHHHHHHHHHHHHCCCCEEEEEEEEECCCCCEEEECCCEEEEEEECCCCCCHHHHHHHHH
AAAAPQYVKAEDVPADVVAKEKEIQLAIAVESGKPEAIAEKMVAGRMAKFSGEVSLTSQP
HHCCCCCEECCCCCHHHHCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHCCCCEEECCCC
FIKDPSIKVAKLLKDAGAEVISFIRLEVGEGIDKKVEDFAAEVAATMAASAK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA