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The map label for this gene is rnhB

Identifier: 119946583

GI number: 119946583

Start: 3654504

End: 3655118

Strand: Reverse

Name: rnhB

Synonym: Ping_2962

Alternate gene names: 119946583

Gene position: 3655118-3654504 (Counterclockwise)

Preceding gene: 119946584

Following gene: 119946582

Centisome position: 80.16

GC content: 43.74

Gene sequence:

>615_bases
ATGAGTAAATTGAAAATTGACTTTCCAGCTGTTGTGTATCCCGATTTTACTTTGATTGCCGGTGTTGATGAGGTGGGTCG
AGGTCCCTTAGTCGGCGATGTGGTGACCGCCTGTGTTATTCTGGATGCCAATAATCCTATATCGGGTTTAGCCGATTCTA
AAAAACTTAGTGAAAAGAAACTGGCACTGTTGTTTGATGAGATCCAGGAAAAAGCCTTGTTTGTTGCCGTGGGCCGCGCC
TCTCCTGTGGAAATAGATGCGCTTAATATTTTGCATGCGACTATGCTTGCGATGCAGCGTGCGGTTGATAATCTAAGCAT
TTCCCCGGAATTTGTCTTTATTGACGGCAACCGTTGTCCTCAATTGAGCATGCCCTGTGAAAGTGTTGTGAAGGGCGATG
CGCGTGTTGCCGAAATAAGTGCCGCATCTATTATTGCGAAGGTCACCCGAGATCGGGAAATGTGTGAACTAGATAAACAA
TATCCACACTATGGATTTGCTAAGCATAAAGGCTATCCTACCAAAGCGCATTTTGCAGCAATTGAAAAACACGGTGTTAC
CCCTGAATATCGTAAAAGTTTTAAACCCGTTAAAAAAGTACTGGGTTTGTTATAA

Upstream 100 bases:

>100_bases
CCTGCACAAGTTGATTCGTTGCGATGCTGATCGGCAAGCAGCCCAGGCTGTGGTTGATGTGTTAAATAATAAAAAATAAT
AAATAGTAATAGAGCATAAT

Downstream 100 bases:

>100_bases
TGGTCAATTGAAGCAAAATAAGATCAGTGTATATTGTTAAATTTTTAAGCCGTTAAATACCTGCGGGTAGGTTATCTGAA
TAATAGTAAAGTTATAAAAT

Product: ribonuclease H

Products: NA

Alternate protein names: RNase HII

Number of amino acids: Translated: 204; Mature: 203

Protein sequence:

>204_residues
MSKLKIDFPAVVYPDFTLIAGVDEVGRGPLVGDVVTACVILDANNPISGLADSKKLSEKKLALLFDEIQEKALFVAVGRA
SPVEIDALNILHATMLAMQRAVDNLSISPEFVFIDGNRCPQLSMPCESVVKGDARVAEISAASIIAKVTRDREMCELDKQ
YPHYGFAKHKGYPTKAHFAAIEKHGVTPEYRKSFKPVKKVLGLL

Sequences:

>Translated_204_residues
MSKLKIDFPAVVYPDFTLIAGVDEVGRGPLVGDVVTACVILDANNPISGLADSKKLSEKKLALLFDEIQEKALFVAVGRA
SPVEIDALNILHATMLAMQRAVDNLSISPEFVFIDGNRCPQLSMPCESVVKGDARVAEISAASIIAKVTRDREMCELDKQ
YPHYGFAKHKGYPTKAHFAAIEKHGVTPEYRKSFKPVKKVLGLL
>Mature_203_residues
SKLKIDFPAVVYPDFTLIAGVDEVGRGPLVGDVVTACVILDANNPISGLADSKKLSEKKLALLFDEIQEKALFVAVGRAS
PVEIDALNILHATMLAMQRAVDNLSISPEFVFIDGNRCPQLSMPCESVVKGDARVAEISAASIIAKVTRDREMCELDKQY
PHYGFAKHKGYPTKAHFAAIEKHGVTPEYRKSFKPVKKVLGLL

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids

COG id: COG0164

COG function: function code L; Ribonuclease HII

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family

Homologues:

Organism=Escherichia coli, GI1786380, Length=192, Percent_Identity=67.1875, Blast_Score=265, Evalue=2e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNH2_PSYIN (A1SYU9)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_944263.1
- ProteinModelPortal:   A1SYU9
- SMR:   A1SYU9
- STRING:   A1SYU9
- GeneID:   4623478
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_2962
- eggNOG:   COG0164
- HOGENOM:   HBG584843
- OMA:   RLGPTPI
- PhylomeDB:   A1SYU9
- BioCyc:   PING357804:PING_2962-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00052_B
- InterPro:   IPR022898
- InterPro:   IPR001352
- InterPro:   IPR012337
- PANTHER:   PTHR10954

Pfam domain/function: PF01351 RNase_HII; SSF53098 RNaseH_fold

EC number: =3.1.26.4

Molecular weight: Translated: 22267; Mature: 22136

Theoretical pI: Translated: 7.97; Mature: 7.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKLKIDFPAVVYPDFTLIAGVDEVGRGPLVGDVVTACVILDANNPISGLADSKKLSEKK
CCCEECCCCEEECCCCCEEECCHHHCCCCCHHHHHHEEEEEECCCCCCCCCCHHHHHHHH
LALLFDEIQEKALFVAVGRASPVEIDALNILHATMLAMQRAVDNLSISPEFVFIDGNRCP
HHHHHHHHHHCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCC
QLSMPCESVVKGDARVAEISAASIIAKVTRDREMCELDKQYPHYGFAKHKGYPTKAHFAA
CCCCCHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHCCCCCCHHHHHH
IEKHGVTPEYRKSFKPVKKVLGLL
HHHCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SKLKIDFPAVVYPDFTLIAGVDEVGRGPLVGDVVTACVILDANNPISGLADSKKLSEKK
CCEECCCCEEECCCCCEEECCHHHCCCCCHHHHHHEEEEEECCCCCCCCCCHHHHHHHH
LALLFDEIQEKALFVAVGRASPVEIDALNILHATMLAMQRAVDNLSISPEFVFIDGNRCP
HHHHHHHHHHCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCC
QLSMPCESVVKGDARVAEISAASIIAKVTRDREMCELDKQYPHYGFAKHKGYPTKAHFAA
CCCCCHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHCCCCCCHHHHHH
IEKHGVTPEYRKSFKPVKKVLGLL
HHHCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA